Reviewing a Role for the Gut Microbiome in Degenerative Aging
There is a growing interest in the manipulation of the gut microbiome. Changes in the balance of microbial populations occur with age, leading to an increase in harmful, inflammatory species at the expense of species that produce beneficial metabolites. Animal studies have demonstrated that even radical changes in the microbiome from a one-time procedure, such as that produced by fecal microbiota transplant from a young individual, can be sustained over time, rejuvenating the balance of microbial populations and improving health as a result. As yet there seems to be little enthusiasm or funding to run clinical trials in ol...
Source: Fight Aging! - June 6, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
What is intelligence: A psycho-physiological paradigm article
Conclusion: More elaborate understanding of brain may help the world embrace its diversity and coexist joyfully through mutual cooperation. Based on initial findings of a preliminary paradigm, further detailed genetic studies may be integrated to establish whether intelligence is constitutional or modifiable. This is the full abstract presented at the American Physiology Summit 2023 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.****************************************** Kevin S. McGrew,...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - June 4, 2023 Category: Neuroscience Source Type: blogs
Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation.
Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field
https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/
Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred yea...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How the Arts transform our Brains, Bodies, and Minds
One of my favorite sayings comes from David Thoreau: “My life has been the poem I would have writ / But I could not both live and utter it.” It speaks to the way that life and art are intertwined, and how we gain so much from living life with a sense of beauty and aesthetics in mind.
There are many ways art infuses my own life—from singing and playing guitar to reading novels and attending plays, which all help to improve my mood and enhance my sense of wonder with the world. Probably, neuroaesthetics many of you feel the same way. Some of you may have felt you’ve even been saved by art.
Now, a new book, Your Brai...
Source: SharpBrains - May 31, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning art neuroaesthetics Your Brain on Art Source Type: blogs
The power of being present
I’ve been listening to Prof Kevin Vowles recently, as he presents his approach to pain using ACT. He made an important point about mindfulness that resonated with me: it’s that when learning to be fully present, it’s not how long we stray from our point of focus, nor even how many times we come back, the learning is that we can come back. Again and again and again.
There are arguments about what mindfulness is, and I’m certain these will continue, but for the purposes of this post and for people just learning mindfulness, I’m defining it as the deliberate practice of attending to a focus (t...
Source: HealthSkills Weblog - May 28, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Chronic pain Coping strategies Professional topics Research hypnosis mindfulness Therapeutic approaches Source Type: blogs
Soft Robotic Electrode Enables Minimally Invasive Placement
Researchers at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have developed a soft robotic electrode, that can be advanced through a small hole in the skull and then opened into a series of spiral arms, to provide electrocorticography measurements from a relatively large area of the brain surface. The technology could prove very useful for brain surgeons who wish to map regions of the brain that may be triggering epileptic seizures and then target these lesions surgically. Reducing the area of the skull that is removed during surgery helps to speed patient recovery and reduce the trauma associated with s...
Source: Medgadget - May 23, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Neurology Neurosurgery EPFL Source Type: blogs
Final week to nominate teachers for the $1M Global Teacher Prize 2023
Dear friends,
We hope you are doing well.
There is now less than one week to go until applications and nominations close for the Global Teacher Prize, and we wanted to ask you to help us spread the word. The Global Teacher Prize serves to underline the importance of educators and the fact that, throughout the world, their efforts deserve to be recognised and celebrated. It seeks to acknowledge the impact of the very best teachers – not only on their students but on the communities around them.
Teachers applying for the Global Teacher Prize will be assessed on teaching practices, how they innovate to address local challen...
Source: SharpBrains - May 22, 2023 Category: Neuroscience Authors: The Varkey Foundation Tags: Education & Lifelong Learning Global Teacher Prize teachers Varkey Foundation Source Type: blogs
Fight Aging! Newsletter, May 22nd 2023
Conclusions to be Drawn
A High Fat Diet Accelerates Atherosclerosis Less Directly than One Might Suspect
How to Construct Measures of Biological Age
A Long-Term Comparison of Metformin in Diabetics with Non-Diabetic Controls
In Search of Distinctive Features of the Gut Microbiome in Long-Lived Individuals
Greater Fitness in Humans Implies a Younger Epigenome and Transcriptome
Intestinal Barrier Dysfunction as a Feature of Aging in Many Species
NAFLD as an Age-Related Condition
Towards Sensory Hair Cell Regeneration in the Inner Ear
Raised Leve...
Source: Fight Aging! - May 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Smartphone-based cognitive behavioral therapy found to significantly decrease insomnia, substantially outperforming sleep education
This study was a single-blinded RCT conducted from March 2021 to January 2022, with screening and randomization conducted at Peking University First Hospital in China. Following eligibility assessment, eligible participants were enrolled and allocated 1:1 to DCBT‑I or sleep education groups, and data were evaluated from January to February 2022. A total of 82 participants were included in the study, with 41 randomized to sleep education and 41 randomized to DCBT‑I.
The DCBT‑I group significantly outperformed the control group in improved insomnia severity and subjective sleep quality, demonstrating the intervention...
Source: SharpBrains - May 17, 2023 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Chinese cognitive-behavioral-therapy DCBT-I digital cognitive behavioral therapy for insomnia insomnia severity randomized clinical trial sleep education Source Type: blogs
The 21st century engram - Robins - WIREs Cognitive Science - Wiley Online Library
The 21st century engram - Robins - WIREs Cognitive Science - Wiley Online Library https://wires.onlinelibrary.wiley.com/doi/10.1002/wcs.1653Socioeconomic status (SES) is associated with children ' s brain and behavioral development. Several theories propose that early experiences of adversity or low SES can alter the pace of neurodevelopment during childhood and adolescence. These theories make contrasting predictions about whether adverse experiences and low SES are associated with accelerated or delayed neurodevelopment. We contextualize these predictions within the context of normative development of cortica...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - May 13, 2023 Category: Neuroscience Source Type: blogs
Childhood socioeconomic status and the pace of structural neurodevelopment: accelerated, delayed, or simply different?: Trends in Cognitive Sciences
Childhood socioeconomic status and the pace of structural neurodevelopment: accelerated, delayed, or simply different?: Trends in Cognitive Sciences https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(23)00073-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1364661323000736%3Fshowall%3DtrueSocioeconomic status (SES) is associated with children ' s brain and behavioral development. Several theories propose that early experiences of adversity or low SES can alter the pace of neurodevelopment during childhood and adolescence. These theories make contrasting predictions about w...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - May 13, 2023 Category: Neuroscience Source Type: blogs
Unlocking the science of memory: How to remember better and forget less [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join us as we sit down with neurologist Andrew Budson, co-author of the book Why We Forget and How To Remember Better: The Science Behind Memory. Andrew shares his personal journey into the field of neurology and his passion for understanding the inner workings
Read more…
Unlocking the science of memory: How to remember better and forget less [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 10, 2023 Category: General Medicine Authors: The Podcast by KevinMD Tags: Podcast Neurology Source Type: blogs
Should doctors prescribe lecanemab (Leqembi) to women? The answer, given available evidence, is probably No
This article is an edited combination of two previous blog posts by him at www.skin2neuron.org.
News in Context:
CMS: anti-amyloid drug Leqembi (lecanemab) doesn’t meet the “reasonable and necessary” standard required for wider Medicare coverage
The post Should doctors prescribe lecanemab (Leqembi) to women? The answer, given available evidence, is probably No appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - May 10, 2023 Category: Neuroscience Authors: Prof. Michael Valenzuela Tags: Brain/ Mental Health amyloid amyloid antibodies amyloid removal CLARITY trial Clinical Dementia Rating immunotherapy lecanemab Leqembi women Source Type: blogs
I'm thinking about moving this blog...
...to another platform. Hi, it ' s been a while. I haven ' t written anything this year. My last post was December 31, 2022.The main reason is that I ' ve had to deal with more loss and grief in my life. Someone close to me was diagnosed with cancer, endured months of radiation and chemotherapy, and died anyway.1 I ' ve also had some deflating garbage to wade through at work. My enthusiasm for doing anything has been rather low.Besides all that, Blogger is aterrible platform for blogging. The interface changed a while a back and ever since then, composing in the little box has been unpleasant. It takes forever t...
Source: The Neurocritic - May 9, 2023 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
Deep Elaboration & Other Stories of Teaching Anatomy & Physiology | TAPP 136
In Episode 136, host Kevin Patton looks at theeffects of tattoos on sweat glands, we discussaural diversity and how we can accommodate it, and we explore how to use the process ofdeep elaboration in our course to help challenged learners develop stronger and more useful memories.00:00 | Introduction00:47 | Tattoos May Impair Sweating05:37 | Sponsored by AAA06:41 | Aural Diversity. It ' s a Thing.22:36 | Sponsored by HAPI24:03 | Deep Elaboration34:22 | Sponsored by HAPS35:29 | Deeper Elaboration47:53 | Staying Connected ★ If you cannot see or activate the audio player, go to:theAPprofessor.org/podcast-...
Source: The A and P Professor - May 9, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs
