< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
High efficient COVID-19 waste co-pyrolysis char/TiO < sub > 2 < /sub > nanocomposite for photocatalytic reduction of Cr(VI) under visible light
This study investigates the effects of Biochar/titania photocatalyst preparation, characterization, and its photoreduction of Cr(VI). The morphological and functional modifications in the catalyst were identified using X-Ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy, ultraviolet spectrophotometer, surface area analysis, and Raman spectrophotometer, respectively. The influencing parameters, namely, pH, photocatalyst dosage, initial pollutant concentration, and visible light irradiation time, have been investigated. The findings reveal that the Cr(VI) reduction by the photocatalyst wa...
Source: Environmental Science and Pollution Research International - August 16, 2023 Category: Environmental Health Authors: Tamilarasan Nallaselvam Sakthivel Rajamohan Balaji Kalaiarasu Anh Tuan Hoang Source Type: research
Enhanced immune responses in dexamethasone immunosuppressed male rats supplemented with herbal extracts, chitosan nanoparticles, and their conjugates
Int J Biol Macromol. 2023 Aug 11:126170. doi: 10.1016/j.ijbiomac.2023.126170. Online ahead of print.ABSTRACTNowadays, the world is challenged with highly contagious diseases, one of their preliminary virulence mechanisms is the suppression of innate immunity. Therefore, promoting natural immunity is a good precautionary strategy. we investigated and compared the effects of several natural herbal extracts -Moringa oleifera, Ziziphus spina christi, and Saussurea costus, and chitosan nanoparticles (CS NPs)- as well as conjugated extracts with CS NPs on the immunological parameters of dexamethasone immunosuppressed (IS) male r...
Source: Cancer Control - August 13, 2023 Category: Cancer & Oncology Authors: Selvia S Milad Sara E Ali Mahmoud Z Attia Marwa S Khattab Eman S El-Ashaal Hisham A Elshoky Afaf M Azouz Source Type: research
Enhanced immune responses in dexamethasone immunosuppressed male rats supplemented with herbal extracts, chitosan nanoparticles, and their conjugates
Int J Biol Macromol. 2023 Aug 11:126170. doi: 10.1016/j.ijbiomac.2023.126170. Online ahead of print.ABSTRACTNowadays, the world is challenged with highly contagious diseases, one of their preliminary virulence mechanisms is the suppression of innate immunity. Therefore, promoting natural immunity is a good precautionary strategy. we investigated and compared the effects of several natural herbal extracts -Moringa oleifera, Ziziphus spina christi, and Saussurea costus, and chitosan nanoparticles (CS NPs)- as well as conjugated extracts with CS NPs on the immunological parameters of dexamethasone immunosuppressed (IS) male r...
Source: International Journal of Biological Macromolecules - August 13, 2023 Category: Biochemistry Authors: Selvia S Milad Sara E Ali Mahmoud Z Attia Marwa S Khattab Eman S El-Ashaal Hisham A Elshoky Afaf M Azouz Source Type: research
Identification of allergens in Artocarpus heterophyllus, Moringa oleifera, Trianthema portulacastrum and Syzygium samarangense
This study ... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - August 11, 2023 Category: Allergy & Immunology Authors: Janitha Iddagoda, Peshala Gunasekara, Shiroma Handunnetti, Chandima Jeewandara, Chandima Karunatilake, Gathsaurie Neelika Malavige, Rajiva de Silva and Dhanushka Dasanayake Tags: Research Source Type: research
Emission study on a direct injection diesel engine powered with blends of Moringa oleifera biodiesel ‐diesel
AbstractThe current investigation uses biodiesel extracted fromMoringa oleifera seeds in a diesel engine.M. oleifera biodiesel is prepared via conventional transesterification with standard conditions (60 °C reaction temperature, 120 min reaction time, 1% by wt. catalyst, and 7.5:1 molar ratio). The test engine is a single-cylinder air-cooled naturally aspirated direct injection diesel engine. The test engine for experimentation is operated at 100% load with different engine speeds ranging from 100 0 to 2400 rpm. Emissions characteristics were analyzed at different engine speeds. Results were interesting as the MB10 ble...
Source: Environmental Quality Management - August 10, 2023 Category: Environmental Health Authors: Harish Venu,
Prabhu Appavu,
Venkatesan Krishnan,
Jayaprabakar Jayaraman,
Mudhu Krishnan Manimuthu,
Sudhakar Kosinapogu,
Dhana Raju Vallapudi Tags: RESEARCH ARTICLE Source Type: research
Kaempferol from Moringa oleifera demonstrated potent antivenom activities via inhibition of metalloproteinase and attenuation of Bitis arietans venom-induced toxicities
Toxicon. 2023 Aug 7:107242. doi: 10.1016/j.toxicon.2023.107242. Online ahead of print.ABSTRACTBitis arietans venom (BAV) can induce severe pathophysiological disorders after envenoming. However, studies have shown that the Moringa oleifera fraction is effective against BAV toxicities and contains bioactive compounds with significant antivenom potency. This research aimed to identify the main active antivenom compound in the M. oleifera fraction responsible for neutralizing the toxicities induced by BAV. The compounds identified from M. oleifera fraction were docked in silico against the catalytic site of the Snake Venom Me...
Source: Toxicon - August 9, 2023 Category: Toxicology Authors: Babafemi Siji Ajisebiola Johnson Olaleye Oladele Akindele Oluwatosin Adeyi Source Type: research
Kaempferol from Moringa oleifera demonstrated potent antivenom activities via inhibition of metalloproteinase and attenuation of Bitis arietans venom-induced toxicities
Toxicon. 2023 Aug 7:107242. doi: 10.1016/j.toxicon.2023.107242. Online ahead of print.ABSTRACTBitis arietans venom (BAV) can induce severe pathophysiological disorders after envenoming. However, studies have shown that the Moringa oleifera fraction is effective against BAV toxicities and contains bioactive compounds with significant antivenom potency. This research aimed to identify the main active antivenom compound in the M. oleifera fraction responsible for neutralizing the toxicities induced by BAV. The compounds identified from M. oleifera fraction were docked in silico against the catalytic site of the Snake Venom Me...
Source: Toxicon - August 9, 2023 Category: Toxicology Authors: Babafemi Siji Ajisebiola Johnson Olaleye Oladele Akindele Oluwatosin Adeyi Source Type: research
Molecules, Vol. 28, Pages 5867: Suppression of Inflamm-Aging by Moringa oleifera and Zingiber officinale Roscoe in the Prevention of Degenerative Diseases: A Review of Current Evidence
pol
Inflammation or inflamm-aging is a chronic low-grade inflammation that contributes to numerous types of degenerative diseases among the elderly and might be impeded by introducing an anti-inflammatory agent like Moringa oleifera Lam (moringa) and Zingiber officinale Roscoe (ginger). Therefore, this paper aims to review the role of moringa and ginger in suppressing inflamm-aging to prevent degenerative diseases. Various peer-reviewed publications were searched and downloaded using the reputed search engine &ldquo;Pubmed&rdquo; and &ldquo;Google Scholar&rdquo;. These materials were rev...
Source: Molecules - August 3, 2023 Category: Chemistry Authors: Nur Fatin Nabilah Mohd Sahardi Suzana Makpol Tags: Review Source Type: research
Neuroprotective and antioxidant potential of Moringa oleifera leaf extract in a murine model of Parkinson's disease
Background: Parkinson ’s disease (PD) is a neurodegenerative disorder characterized by the development of rigidity, resting tremors and postural instability. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - August 1, 2023 Category: Neurology Authors: A. Kumar Source Type: research
Lipid profiles and production performance responses of laying hens to dietary Moringa oleifera leaf meal: systematic review and meta-analysis
In conclusion, the results of this m eta-analysis suggest that inclusion of MLM in the diet of laying hens improved feed conversion ratio, aspects of egg quality and blood/yolk cholesterol concentrations in laying hens at a reduced feed intake. (Source: Tropical Animal Health and Production)
Source: Tropical Animal Health and Production - July 27, 2023 Category: Veterinary Research Source Type: research
Moringa oleifera Leaves Extract Ameliorates Doxorubicin-Induced Cardiotoxicity via Its Mitochondrial Biogenesis Modulatory Activity in Rats
(Source: International Journal of Nanomedicine)
Source: International Journal of Nanomedicine - July 26, 2023 Category: Nanotechnology Tags: Journal of Experimental Pharmacology Source Type: research
Trace Elemental and Heavy Metal Levels in Frequently Consumed Local Vegetables of Three Chronic Kidney Disease-Prevalent Villages
Biol Trace Elem Res. 2023 Jul 10. doi: 10.1007/s12011-023-03761-6. Online ahead of print.ABSTRACTThe present study reports the trace elemental and heavy metal (24 elements) levels in six (Capsicum frutescence L., Carica papaya L., Momordica charantia L., Moringa oleifera Lam., Musa sapientum L., and Solanum melongena L.) vegetables. The vegetable samples are collected from the three villages and are subjected to ICP-MS analysis, to test a group of 24 elements, viz., Li, Be, Al, Sc, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, As, Se, Rb, Sr, Ag, Cd, Cs, Ba, TI, Rb, and U, for their levels. The obtained levels of each element were co...
Source: Biological Trace Element Research - July 10, 2023 Category: Biology Authors: G Narayana Murthy P Balarama Swamy Yadav Source Type: research
Molecules, Vol. 28, Pages 5322: Phytofabrication of Selenium Nanoparticles with Moringa oleifera (MO-SeNPs) and Exploring Its Antioxidant and Antidiabetic Potential
e Hoon Tang
The advancement in nanotechnology is the trigger for exploring the synthesis of selenium nanoparticles and their use in biomedicine. Therefore, this study aims to synthesize selenium nanoparticles using M. oleifera as a reducing agent and evaluate their antioxidant and antidiabetic potential. Our result demonstrated a change in the color of the mixture from yellow to red, and UV-Vis spectrometry of the suspension solution confirmed the formation of MO-SeNPs with a single absorbance peak in the range of 240&ndash;560 nm wavelength. FTIR analysis revealed several bioactive compounds, such as phenols a...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Anas Ahzaruddin Ahamad Tarmizi Nik Nasihah Nik Ramli Siti Hajar Adam Maisarah Abdul Mutalib Mohd Helmy Mokhtar Shirley Gee Hoon Tang Tags: Article Source Type: research
