Impacts of microwave-assisted extraction parameters on total phenolic compounds yield from Algerian < em > Moringa oleifera < /em > leaves, using response surface methodology
Nat Prod Res. 2024 Mar 23:1-9. doi: 10.1080/14786419.2024.2333044. Online ahead of print.ABSTRACTThe study aimed to optimise the microwave-assisted extraction (MAE) of total phenolic compounds (TPC) from Moringa oleifera Lam. leaves using response surface methodology (RSM) and Box-Behnken designs (BBD). Factors such as ethanol concentration, microwave power, irradiation time, and solvent to solid ratio were assessed in single-factor tests. Under optimal extraction conditions (48.86% ethanol, 626.53 W microwave power, 99.48 s irradiation, 29.67 mL/g solvent to solid ratio and 21.12 W/mL power density), TPC was 58.45 ± 0.68...
Source: Natural Product Research - March 23, 2024 Category: Biochemistry Authors: Farida Kheyar Naoual Kheyar Malek Amiali Lila Boulekbache-Makhlouf Ahcene Kadi Ahmed Benchabane Arezki Bitam Source Type: research

Impacts of microwave-assisted extraction parameters on total phenolic compounds yield from Algerian < em > Moringa oleifera < /em > leaves, using response surface methodology
Nat Prod Res. 2024 Mar 23:1-9. doi: 10.1080/14786419.2024.2333044. Online ahead of print.ABSTRACTThe study aimed to optimise the microwave-assisted extraction (MAE) of total phenolic compounds (TPC) from Moringa oleifera Lam. leaves using response surface methodology (RSM) and Box-Behnken designs (BBD). Factors such as ethanol concentration, microwave power, irradiation time, and solvent to solid ratio were assessed in single-factor tests. Under optimal extraction conditions (48.86% ethanol, 626.53 W microwave power, 99.48 s irradiation, 29.67 mL/g solvent to solid ratio and 21.12 W/mL power density), TPC was 58.45 ± 0.68...
Source: Natural Product Research - March 23, 2024 Category: Biochemistry Authors: Farida Kheyar Naoual Kheyar Malek Amiali Lila Boulekbache-Makhlouf Ahcene Kadi Ahmed Benchabane Arezki Bitam Source Type: research

Molecules, Vol. 29, Pages 1380: Phytochemical Profiling by UHPLC & ndash;Q-TOF/MS and Chemopreventive Effect of Aqueous Extract of Moringa oleifera Leaves and Benzyl Isothiocyanate on Murine Mammary Carcinogenesis
In conclusion, this study suggests that both the aqueous extract of Moringa oleifera leaves and the benzyl isothiocyanate possess antitumor properties against mammary carcinogenesis, and this effect could be due, at least in part, to the flavonoids and isothiocyanates present in the extract. (Source: Molecules)
Source: Molecules - March 20, 2024 Category: Chemistry Authors: Juan Pedro Rojas-Armas Miriam Palomino-Pacheco Jorge Luis Arroyo-Acevedo Jos é Manuel Ortiz-Sánchez Hugo Jes ús Justil-Guerrero Jaime Teodocio Mart ínez-Heredia Am érico Castro-Luna Crescencio Rodr íguez Flores Aldo Javier Guzm án Duxtan Tags: Article Source Type: research

The effect of Channa striata, Moringa oleifera, and Curcuma xanthorrhiza extract on accelerating recovery in a ventilated patient with hemorrhagic shock grade 3 due to prolonged retained placenta: a case report
ConclusionThis is the first case report describing the effect ofC. striata,M. oleifera, andC. xanthorrhiza extract in a patient with severe hemorrhagic shock due to a prolonged placenta. Accelerated recovery showed the possibility benefit ofC. striata,M. oleifera, andC. xanthorrhiza extract in stabilizing oncotic pressure, neutralizing free radicals, and preventing further damage in hypoxic cells. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 19, 2024 Category: General Medicine Source Type: research

Modulatory effects of Moringa oleifera leaf extract on sodium nitrate-induced experimental colitis via regulation of P53, Ki-67 and PCNA biomarkers
CONCLUSION: MO protected the colonic mucosa against SN-induced changes regulating apoptosis, and cell proliferation.PMID:38493756 | DOI:10.1016/j.tice.2024.102327 (Source: Tissue and Cell)
Source: Tissue and Cell - March 17, 2024 Category: Cytology Authors: Hend M Hassan Wael M Elsaed Dina Elzeiny Ola Ali Habotta Elshimaa S Eleraky Eman Mohamed El Nashar Mansour Abdullah Alghamdi Rashid A Aldahhan Mohammed Attieh Alzahrani Ali Mohni Saleh Alamari Eman Hamza Source Type: research

Modulatory effects of Moringa oleifera leaf extract on sodium nitrate-induced experimental colitis via regulation of P53, Ki-67 and PCNA biomarkers
CONCLUSION: MO protected the colonic mucosa against SN-induced changes regulating apoptosis, and cell proliferation.PMID:38493756 | DOI:10.1016/j.tice.2024.102327 (Source: Tissue and Cell)
Source: Tissue and Cell - March 17, 2024 Category: Cytology Authors: Hend M Hassan Wael M Elsaed Dina Elzeiny Ola Ali Habotta Elshimaa S Eleraky Eman Mohamed El Nashar Mansour Abdullah Alghamdi Rashid A Aldahhan Mohammed Attieh Alzahrani Ali Mohni Saleh Alamari Eman Hamza Source Type: research

Molecules, Vol. 29, Pages 1297: The Indiscriminate Chemical Makeup of Secondary Metabolites Derived from Endophytes Harvested from Aloe barbadensis Miller in South Africa & rsquo;s Limpopo Region
Molecules, Vol. 29, Pages 1297: The Indiscriminate Chemical Makeup of Secondary Metabolites Derived from Endophytes Harvested from Aloe barbadensis Miller in South Africa&rsquo;s Limpopo Region Molecules doi: 10.3390/molecules29061297 Authors: Mpho Mamphoka Nchabeleng Thierry Youmbi Fonkui Green Ezekiel The efficacy of 23 bacterial isolates obtained from surface-sterilized stems and leaves of three medicinal plants (Aloe barbadensis Miller, Artemisia afra, and Moringa oleifera) was investigated in an endeavour to prevent the growth of Mycobacterium bovis using the cross-streak method. Endophytes were isolat...
Source: Molecules - March 14, 2024 Category: Chemistry Authors: Mpho Mamphoka Nchabeleng Thierry Youmbi Fonkui Green Ezekiel Tags: Article Source Type: research

Reversal of valproate-induced major salivary gland changes by moringa oleifera extract in rats
This study aimed to explore the potential protective impacts of Moringa oleifera extract on major alteration in salivary glands of rats exposed to sodium valproate (VA). Groups were defined as control, control + moringa extract, sodium valproate, and sodium valproate + moringa extract. Antioxidant and oxidant status, activities of digestive and metabolic enzymes were examined. VA treatment led to various biochemical changes in the salivary glands, including decreased levels of antioxidants like glutathione, glutathione-S-transferase, and superoxide dismutase (except for sublingual superoxide dismutase). Conversely, a decre...
Source: Chemistry and Biodiversity - March 12, 2024 Category: Biochemistry Authors: Eda Cergel Burcin Alev Tuzuner Ismet Burcu Turkyilmaz Sehkar Oktay Umar Faruk Magaji Ozlem Sacan Refiye Yanardag Aysen Yarat Source Type: research

Reversal of valproate-induced major salivary gland changes by moringa oleifera extract in rats
This study aimed to explore the potential protective impacts of Moringa oleifera extract on major alteration in salivary glands of rats exposed to sodium valproate (VA). Groups were defined as control, control + moringa extract, sodium valproate, and sodium valproate + moringa extract. Antioxidant and oxidant status, activities of digestive and metabolic enzymes were examined. VA treatment led to various biochemical changes in the salivary glands, including decreased levels of antioxidants like glutathione, glutathione-S-transferase, and superoxide dismutase (except for sublingual superoxide dismutase). Conversely, a decre...
Source: Chemistry and Biodiversity - March 12, 2024 Category: Biochemistry Authors: Eda Cergel Burcin Alev Tuzuner Ismet Burcu Turkyilmaz Sehkar Oktay Umar Faruk Magaji Ozlem Sacan Refiye Yanardag Aysen Yarat Source Type: research

< em > Moringa oleifera < /em > leaves ethanolic extract counteracts cortical neurodegeneration induced by aluminum chloride in rats
CONCLUSIONS: We concluded that MOE exhibits protective effects against cortical neurodegeneration, making it a promising supplement to counteract aluminum-induced neurotoxic effects.PMID:38455639 | PMC:PMC10917235 | DOI:10.1093/toxres/tfae028 (Source: Cell Research)
Source: Cell Research - March 8, 2024 Category: Cytology Authors: Rabab Fawzy Hindawy Samia M Manawy Ola Elsayed Nafea Abeer A Abdelhameed Fatma Fawzi Hendawi Source Type: research

Leaf Extracts of < em > Moringa oleifera < /em > Cultivated in Baghdad: Characterization and Antimicrobial Potential against Endodontic Pathogens
Conclusion. Ethanolic and aqueous extracts of Moringa oleifera leaves cultivated in Baghdad contain considerable quantities of phytochemicals, especially flavonoid and phenolic compounds, and demonstrated antimicrobial activities against selected endodontic pathogens. Therefore, Moringa leaf extracts could be suggested as an alternative antimicrobial material in endodontic treatment.PMID:38450244 | PMC:PMC10917486 | DOI:10.1155/2024/6658164 (Source: The Scientific World Journal)
Source: The Scientific World Journal - March 7, 2024 Category: Science Authors: Nada E Shafiq Anas F Mahdee Zainab Y Mohammed Hasan Source Type: research