Ultrasonic extraction of Moringa oleifera seeds polysaccharides: Optimization, purification, and anti-inflammatory activities
This study indicates that polysaccharides (MOSP-1) from Moringa oleifera seeds with anti-inflammatory properties may be used for functional food and pharmaceutical product development.PMID:38128806 | DOI:10.1016/j.ijbiomac.2023.128833 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - December 21, 2023 Category: Biochemistry Authors: Yao Peng Xucheng Zhu Guiyan Yang Junjia Zhang Rui Wang Yingbin Shen Haimei Li Mansour K Gatasheh Arshad Mehmood Abbasi Xinquan Yang Source Type: research
Ultrasonic extraction of Moringa oleifera seeds polysaccharides: Optimization, purification, and anti-inflammatory activities
This study indicates that polysaccharides (MOSP-1) from Moringa oleifera seeds with anti-inflammatory properties may be used for functional food and pharmaceutical product development.PMID:38128806 | DOI:10.1016/j.ijbiomac.2023.128833 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - December 21, 2023 Category: Biochemistry Authors: Yao Peng Xucheng Zhu Guiyan Yang Junjia Zhang Rui Wang Yingbin Shen Haimei Li Mansour K Gatasheh Arshad Mehmood Abbasi Xinquan Yang Source Type: research
Moringa oleifera leaf alleviates functional constipation via regulating the gut microbiota and the enteric nervous system in mice
Moringa oleifera Lam. leaf is not only a new food resource in China, but also a traditional medicinal plant. It is commonly used in the folk to alleviate constipation, but its laxative mechanism is not fully understood. Hence we investigated it in loperamide-induced functional constipation (FC) mice. The results showed that MOAE significantly regulated not only gastrointestinal hormones and neurotransmitters in serum but also important gastrointestinal motility factors in the enteric nervous system (ENS)-interstitial cells of Cajal (ICCs)-smooth muscle cell (SMC) network. Meanwhile, MOAE attenuated intestinal inflammation,...
Source: Frontiers in Microbiology - December 20, 2023 Category: Microbiology Source Type: research
Evaluation of antioxidant, anti-inflammatory, anticancer activities and molecular docking of Moringa oleifera seed oil extract against experimental model of Ehrlich ascites carcinoma in Swiss female albino mice
The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: co... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - December 14, 2023 Category: Complementary Medicine Authors: Tahany Saleh Aldayel, Heba N. Gad El Hak, Mohamed S. Nafie, Raneem Saad, Heba M. A. Abdelrazek and Omnia E. Kilany Tags: Research Source Type: research
Molecules, Vol. 28, Pages 8035: In Silico Design of Natural Inhibitors of ApoE4 from the Plant Moringa oleifera: Molecular Docking and Ab Initio Fragment Molecular Orbital Calculations
ki Kurita
Alzheimer’s disease (AD) is a neurological disease, and its signs and symptoms appear slowly over time. Although current Alzheimer’s disease treatments can alleviate symptoms, they cannot prevent the disease from progressing. To accurately diagnose and treat Alzheimer’s disease, it is therefore necessary to establish effective methods for diagnosis. Apolipoprotein E4 (ApoE4), the most frequent genetic risk factor for AD, is expressed in more than half of patients with AD, making it an attractive target for AD therapy. We used molecular docking simulations, classical m...
Source: Molecules - December 11, 2023 Category: Chemistry Authors: Divya Shaji Yoshinobu Nagura Haruna Sabishiro Ryo Suzuki Noriyuki Kurita Tags: Article Source Type: research
Pathological effects of feeding aflatoxin-contaminated feed on immune status and reproductive performance of juvenile white leghorn males and its mitigation with ∝-tocopherol and Moringa oleifera
This study was planned to detect the adverse pathological consequences of aflatoxin B1 in White Leghorn (WLH) layer breeder males. Eight-week-old male layer cockerels were separated into six experimental categories: A group was kept as negative control, offered with normal feed only; group B was fed with 400 ppb amount of aflatoxin, while groups F and D fed with normal feed and supplemented with vitamin E 100 ppm and 1% Moringa oleifera, respectively, whereas groups E and C were fed with 400 ppb aflatoxin containing feed and ameliorated with vitamin E 100 ppm and 1% Moringa oleifera, respectively. This study was continued ...
Source: Environmental Science and Pollution Research International - December 6, 2023 Category: Environmental Health Authors: Muhammad Kashif Saleemi Ahmad Raza Aisha Khatoon Muhammad Zubair Shafia Tehseen Gul Xu Yongping Bilal Murtaza Faqir Muhammad Bushra Akhtar Farhat Jubeen Farzana Rizvi Khawar Zubair Anas Ashraf Muhammad Nabeel Ijaz Asim Sultan Source Type: research
Exploring the potential of Moringa oleifera Lam in skin disorders and cosmetics: nutritional analysis, phytochemistry, geographical distribution, ethnomedicinal uses, dermatological studies and cosmetic formulations
Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec 6. doi: 10.1007/s00210-023-02862-2. Online ahead of print.ABSTRACTMoringa oleifera Lam. is a pan-tropical plant well known to the ancient world for its extensive therapeutic benefits in the Ayurvedic and Unani medical systems. The ancient world was familiar with this tree, but it has only lately been rediscovered as a multifunctional species with a huge range of possible therapeutic applications. It is a folk remedy for skin diseases, edema, sore gums, etc. This review comprises the history, ethnomedicinal applications, botanical characteristics, geographic distribution, propag...
Source: Herpes - December 6, 2023 Category: Infectious Diseases Authors: Prakrati Garg Swati Pundir Aaliya Ali Sebika Panja Dinesh Kumar Chellappan Kamal Dua Saurabh Kulshrestha Poonam Negi Source Type: research
Protein extracted from Moringa oleifera Lam. Leaves: Bio-evaluation and characterization as suitable plant-based meat-protein alternative
This study aimed to isolate and characterize moringa leaf protein (MLP) via HPLC and evaluate its consumption's effects through rat model. Four groups of Albino Wistar rats (n = 25 each) along with a control group (n = 25) were acclimatized. The isolated MLP was added to the basal diet (casein; control) in various percentages (25, 50, 75, 100%) for a 21-day experimental period. On three intervals (1st, 11th, 21st days), blood samples were collected and subjected for hematological and biochemical examination (Renal Function Test (RFT), Liver Function Test (LFT)). MLP contained a variety of essential and non-essential amino ...
Source: Regulatory Toxicology and Pharmacology : RTP - December 6, 2023 Category: Toxicology Authors: Muhammad Sameem Javed Smara Qaiser Alvi Adnan Amjad Hasan Sardar Muhammad Junaid Anwar Asma Javid Sami Abou Fayssal Pankaj Kumar Tracy Abou Fayssal Saikh M Wabaidur Mohammad K Okla Ibrahim A Saleh Hamada AbdElgawad Source Type: research
Pathological effects of feeding aflatoxin-contaminated feed on immune status and reproductive performance of juvenile white leghorn males and its mitigation with ∝-tocopherol and Moringa oleifera
This study was planned to detect the adverse pathological consequences of aflatoxin B1 in White Leghorn (WLH) layer breeder males. Eight-week-old male layer cockerels were separated into six experimental categories: A group was kept as negative control, offered with normal feed only; group B was fed with 400 ppb amount of aflatoxin, while groups F and D fed with normal feed and supplemented with vitamin E 100 ppm and 1% Moringa oleifera, respectively, whereas groups E and C were fed with 400 ppb aflatoxin containing feed and ameliorated with vitamin E 100 ppm and 1% Moringa oleifera, respectively. This study was continued ...
Source: Environmental Science and Pollution Research International - December 6, 2023 Category: Environmental Health Authors: Muhammad Kashif Saleemi Ahmad Raza Aisha Khatoon Muhammad Zubair Shafia Tehseen Gul Xu Yongping Bilal Murtaza Faqir Muhammad Bushra Akhtar Farhat Jubeen Farzana Rizvi Khawar Zubair Anas Ashraf Muhammad Nabeel Ijaz Asim Sultan Source Type: research
Protein extracted from Moringa oleifera Lam. Leaves: Bio-evaluation and characterization as suitable plant-based meat-protein alternative
This study aimed to isolate and characterize moringa leaf protein (MLP) via HPLC and evaluate its consumption's effects through rat model. Four groups of Albino Wistar rats (n = 25 each) along with a control group (n = 25) were acclimatized. The isolated MLP was added to the basal diet (casein; control) in various percentages (25, 50, 75, 100%) for a 21-day experimental period. On three intervals (1st, 11th, 21st days), blood samples were collected and subjected for hematological and biochemical examination (Renal Function Test (RFT), Liver Function Test (LFT)). MLP contained a variety of essential and non-essential amino ...
Source: Regulatory Toxicology and Pharmacology : RTP - December 6, 2023 Category: Toxicology Authors: Muhammad Sameem Javed Smara Qaiser Alvi Adnan Amjad Hasan Sardar Muhammad Junaid Anwar Asma Javid Sami Abou Fayssal Pankaj Kumar Tracy Abou Fayssal Saikh M Wabaidur Mohammad K Okla Ibrahim A Saleh Hamada AbdElgawad Source Type: research
Protein extracted from Moringa oleifera Lam. Leaves: Bio-evaluation and characterization as suitable plant-based meat-protein alternative
This study aimed to isolate and characterize moringa leaf protein (MLP) via HPLC and evaluate its consumption's effects through rat model. Four groups of Albino Wistar rats (n = 25 each) along with a control group (n = 25) were acclimatized. The isolated MLP was added to the basal diet (casein; control) in various percentages (25, 50, 75, 100%) for a 21-day experimental period. On three intervals (1st, 11th, 21st days), blood samples were collected and subjected for hematological and biochemical examination (Renal Function Test (RFT), Liver Function Test (LFT)). MLP contained a variety of essential and non-essential amino ...
Source: Regulatory Toxicology and Pharmacology : RTP - December 6, 2023 Category: Toxicology Authors: Muhammad Sameem Javed Smara Qaiser Alvi Adnan Amjad Hasan Sardar Muhammad Junaid Anwar Asma Javid Sami Abou Fayssal Pankaj Kumar Tracy Abou Fayssal Saikh M Wabaidur Mohammad K Okla Ibrahim A Saleh Hamada AbdElgawad Source Type: research
Nutritional value and therapeutic potential of < em > Moringa oleifera < /em > : a short overview of current research
Nat Prod Res. 2023 Dec 3:1-19. doi: 10.1080/14786419.2023.2284862. Online ahead of print.ABSTRACTA member of the Moringaceae family, Moringa Oleifera Lam is a perennial deciduous tropical tree known as the 'Miracle Tree' for its medicinal and nutritional benefits. Food and nutrition are crucial aspects of the development and maintenance of healthy health. Moringa oleifera is a multi-purpose herbal bush that is used as both human food and a medical alternative all over the world. Various parts of the tree are used to treat chronic diseases such as hypertension, heart disease, inflammation, oxidative stress, diabetes, and ca...
Source: Natural Product Research - December 3, 2023 Category: Biochemistry Authors: Nabila Bibi Nadia Rahman Muhammad Qasim Ali Noormazlinah Ahmad Farzana Sarwar Source Type: research
Nutritional value and therapeutic potential of < em > Moringa oleifera < /em > : a short overview of current research
Nat Prod Res. 2023 Dec 3:1-19. doi: 10.1080/14786419.2023.2284862. Online ahead of print.ABSTRACTA member of the Moringaceae family, Moringa Oleifera Lam is a perennial deciduous tropical tree known as the 'Miracle Tree' for its medicinal and nutritional benefits. Food and nutrition are crucial aspects of the development and maintenance of healthy health. Moringa oleifera is a multi-purpose herbal bush that is used as both human food and a medical alternative all over the world. Various parts of the tree are used to treat chronic diseases such as hypertension, heart disease, inflammation, oxidative stress, diabetes, and ca...
Source: Natural Product Research - December 3, 2023 Category: Biochemistry Authors: Nabila Bibi Nadia Rahman Muhammad Qasim Ali Noormazlinah Ahmad Farzana Sarwar Source Type: research
Nutritional value and therapeutic potential of < em > Moringa oleifera < /em > : a short overview of current research
Nat Prod Res. 2023 Dec 3:1-19. doi: 10.1080/14786419.2023.2284862. Online ahead of print.ABSTRACTA member of the Moringaceae family, Moringa Oleifera Lam is a perennial deciduous tropical tree known as the 'Miracle Tree' for its medicinal and nutritional benefits. Food and nutrition are crucial aspects of the development and maintenance of healthy health. Moringa oleifera is a multi-purpose herbal bush that is used as both human food and a medical alternative all over the world. Various parts of the tree are used to treat chronic diseases such as hypertension, heart disease, inflammation, oxidative stress, diabetes, and ca...
Source: Natural Product Research - December 3, 2023 Category: Biochemistry Authors: Nabila Bibi Nadia Rahman Muhammad Qasim Ali Noormazlinah Ahmad Farzana Sarwar Source Type: research
Isothiocyanate-rich moringa seed extract reduces skin inflammation in mouse ear edema model
CONCLUSION: These results reveal the topical anti-inflammatory properties of MSE, and MIC-1 likely transmitted via the nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor-kappa B (NF-κB) pathways as mentioned in previous studies. This work also suggests therapeutic uses of MSE and/or MIC-1 for skin inflammation.PMID:38037612 | PMC:PMC10688386 | DOI:10.1016/j.phyplu.2023.100479 (Source: Cancer Control)
Source: Cancer Control - December 1, 2023 Category: Cancer & Oncology Authors: Khea Wolff Keyaara Robinson Nanjoo Suh Bozena Michniak-Kohn Michael Goedken Marianne Polunas Ilya Raskin Source Type: research
