Moringa Oleifera Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research

Comparative Neuroprotective Effects of Moringa oleifera Seed Oil and Aqueous Extract on Cognitive Functions on a High-Fat, High-Fructose Diet Mice: Focus on Senescence Markers
This study aimed to investigate the neuroprotective effects of MO leaves aqueous extract (MOE) and moringa seed oil (MOO) against brain impairment in mice with HFFD. Twenty-eight male mice were randomly divided into four groups: normal diet, HFFD, HFFD + MOE 500 mg/kgBW, and HFFD + MOO 2 mL/kgBW. Cognitive function was assessed using the Y-maze and novel object recognition (NOR) tests. The p16, p21, and BDNF expressions were analyzed using the RT-PCR method. Senescence-associated beta-galactosidase (SA-β-gal) staining in the brain was also performed. The results showed that administration of MOE or MOO could increase the ...
Source: The Scientific World Journal - April 18, 2024 Category: Science Authors: Wawaimuli Arozal Muhamad Sadam Safutra Agian Jeffilano Barinda Harri Hardi Nounik Cheri Dwita Hee J Lee Source Type: research

Impact of dietary Moringa oleifera leaf supplementation on gut morphometry, behaviour and physiological parameters in growing male rabbits
AbstractMoringa oleifera (MO), a cultivated species of the Moringa, is known for its high concentration of essential nutrients that promote growth. To assess its impact on rabbits' gut morphometric, behavioural, and physiological parameters, a study was conducted using sixty growing male white New Zealand rabbits at 40 days old. The rabbits were divided into four groups and supplemented with dried MO leaves at varying levels (0%, 0.5%, 1% and 2% of body weight) for four weeks. The results revealed significant increases in organ weights, such as liver and intestinal length, and the height of intestinal villi and crypt depth...
Source: Journal of Animal Physiology and Animal Nutrition - April 18, 2024 Category: Zoology Authors: Seham S. Hadad, Enas K. Aziz, Adel Hassan Saad, Hanem El ‐Gendy, Nazema Abdel‐Megeid, Shimaa R. Masoud, Mustafa Shukry, Ayman A. Swelum, Muath Q. Al‐Ghadi, Ahmad R. Alhimaidi, Guillermo Tellez‐Isaias, Mohamed E. Abd El‐Hack, Mohamed Tags: ORIGINAL ARTICLE Source Type: research

Phytochemicals analysis and aflatoxin B 1 detoxification potential of leaves extract of Moringa oleifera and Calotropis procera 
Nat Prod Res. 2024 Apr 16:1-9. doi: 10.1080/14786419.2024.2342003. Online ahead of print.ABSTRACTThe present study aimed to identify the presence of certain classes of phytochemicals in the leaf extract of medicinal herbs viz. Moringa oleifera and Calotropis procera, using qualitative detection tests and explored the potential of aqueous and ethanolic extract to inhibit aflatoxin production by thin layer chromatography at 25 °C and pH (7) of different incubation times i.e. 0-, 1-, 3-, 6- and 24-h. Qualitative phytochemical analysis reported that the aqueous leave extracts of M. oleifera and C. procera contained tannins, p...
Source: Natural Product Research - April 16, 2024 Category: Biochemistry Authors: Nehrish Nisar Maryam Ajmal Nafeesa Qudsia Hanif Syed Waqas Hassan Source Type: research

Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
CONCLUSION: A combination of A. annua and M. oleifera leaf powders taken once a day together with the routine standard of care produced a significant increase in CD4 count, WBCs, platelets, and viral load suppression among individuals on ART. A. annua and M. oleifera have potential to offer an affordable alternative remedy for managing HIV infection, particularly in low-resource communities lacking ART access.TRIAL REGISTRATION: ClinicalTrials.gov NCT03366922.PMID:38627722 | DOI:10.1186/s12981-024-00609-4 (Source: Cell Research)
Source: Cell Research - April 16, 2024 Category: Cytology Authors: Silvano S Twinomujuni Esther C Atukunda Jackson K Mukonzo Musinguzi Nicholas Felicitas Roelofsen Patrick E Ogwang Source Type: research

Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
CONCLUSION: A combination of A. annua and M. oleifera leaf powders taken once a day together with the routine standard of care produced a significant increase in CD4 count, WBCs, platelets, and viral load suppression among individuals on ART. A. annua and M. oleifera have potential to offer an affordable alternative remedy for managing HIV infection, particularly in low-resource communities lacking ART access.TRIAL REGISTRATION: ClinicalTrials.gov NCT03366922.PMID:38627722 | DOI:10.1186/s12981-024-00609-4 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 16, 2024 Category: Infectious Diseases Authors: Silvano S Twinomujuni Esther C Atukunda Jackson K Mukonzo Musinguzi Nicholas Felicitas Roelofsen Patrick E Ogwang Source Type: research

Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
CONCLUSION: A combination of A. annua and M. oleifera leaf powders taken once a day together with the routine standard of care produced a significant increase in CD4 count, WBCs, platelets, and viral load suppression among individuals on ART. A. annua and M. oleifera have potential to offer an affordable alternative remedy for managing HIV infection, particularly in low-resource communities lacking ART access.TRIAL REGISTRATION: ClinicalTrials.gov NCT03366922.PMID:38627722 | PMC:PMC11020329 | DOI:10.1186/s12981-024-00609-4 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 16, 2024 Category: Infectious Diseases Authors: Silvano S Twinomujuni Esther C Atukunda Jackson K Mukonzo Musinguzi Nicholas Felicitas Roelofsen Patrick E Ogwang Source Type: research

Facile fabrication of new bioadsorbents from Moringa oleifera and alginate for efficient removal of uranium(VI)
This article presents the first study on the use of alginate and moringa as an effective adsorbent for uranium treatment under various conditions. A new method of preparing adsorbents was used by addingMoringa oleifera seeds (MOS) to alginate through simple grafting. The resulting beads have a heterogeneous, sponge-like structure that is reversible. The adsorbents were tested for their ability to remove uranium ions from water and showed excellent efficiency with an adsorption capacity of 443.60 mg/g for alginate-PEI-MOS and 341.38 mg/g for alginate-Glu-MOS. Additionally, these adsorbents showed an interesting rate of s...
Source: Journal of Radioanalytical and Nuclear Chemistry - April 16, 2024 Category: Nuclear Medicine Source Type: research

Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
Initiation of ART among people living with HIV (PLWH) having a CD4 count ≤ 350cells/µl, produces poor immunological recovery, putting them at a high risk of opportunistic infections. To mitigate this, PLWH on ... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 16, 2024 Category: Infectious Diseases Authors: Silvano S. Twinomujuni, Esther C Atukunda, Jackson K. Mukonzo, Musinguzi Nicholas, Felicitas Roelofsen and Patrick E. Ogwang Tags: Brief Report Source Type: research

Moringa oleifera and Its Biochemical Compounds: Potential Multi-targeted Therapeutic Agents Against COVID-19 and Associated Cancer Progression
Biochem Genet. 2024 Apr 7. doi: 10.1007/s10528-024-10758-w. Online ahead of print.ABSTRACTThe Coronavirus disease-2019 (COVID-19) pandemic is a global concern, with updated pharmacological therapeutic strategies needed. Cancer patients have been found to be more susceptible to severe COVID-19 and death, and COVID-19 can also lead to cancer progression. Traditional medicinal plants have long been used as anti-infection and anti-inflammatory agents, and Moringa oleifera (M. oleifera) is one such plant containing natural products such as kaempferol, quercetin, and hesperetin, which can reduce inflammatory responses and compli...
Source: Biochemical Genetics - April 7, 2024 Category: Genetics & Stem Cells Authors: Ali Yousefi Rad Ali Asghar Rastegari Kahin Shahanipour Ramesh Monajemi Source Type: research

Phyto-fabrication of Moringa oleifera peel-sourced silver nanoparticles: A promising approach for combating hepatic cancer by targeting proinflammatory cytokines and mitigating cytokine storms
This study focuses on the eco-friendly synthesis of silver nanoparticles infused with M. oleifera peel extract biomolecules and their impact on regulating proinflammatory cytokines, as well as their potential anticancer effects against Wistar rats. The freshly synthesized nanoformulation underwent comprehensive characterization, followed by antihepatic cancer evaluation using a diethyl nitrosamine-induced model (at a dose of 200 mg kg-1 BW). The study demonstrates a significant reduction in proinflammatory cytokines such as tumor necrosis factor-α, interleukin-6, interleukin-1β, and nuclear factor kappa beta (NF-kB). Fur...
Source: Chemistry and Biodiversity - April 7, 2024 Category: Biochemistry Authors: Shahnawaz Sameem Vivek Dwivedi Vikas Kumar Ashish R Dwivedi Prateek Pathak Bhupendra Singh Mashooq Ahmad Bhat Amita Verma Source Type: research

Neuromodulatory effects induced by the association of Moringa oleifera Lam., Tribulus terrestris L., Undaria pinnatidifida extracts in the hypothalamus
Chem Biodivers. 2024 Mar 25:e202302075. doi: 10.1002/cbdv.202302075. Online ahead of print.ABSTRACTThe present study investigated the role of a commercial formulation constituted by herbal extracts from Rhodiola rosea, Undaria pinnatifida, Tribulus terrestris, and Moringa oleifera. The formulation was analysed for determining the content in total phenols and flavonoids and scavenging/reducing properties. The formulation was also tested on isolated mouse hypothalamus in order to investigate effects on serotonin, dopamine, neuropeptide Y (NPY), and orexin A. The gene expression of gonadrotopin releasing hormone (GnRH) was al...
Source: Chemistry and Biodiversity - March 25, 2024 Category: Biochemistry Authors: Annalisa Chiavaroli Simonetta Cristina Di Simone Alessandra Acquaviva Nilofar Nilofar Maria Loreta Libero Luigi Brunetti Lucia Recinella Sheila Leone Giustino Orlando Gokhan Zengin Maura Di Vito Luigi Menghini Claudio Ferrante Source Type: research