Phytochemicals analysis and aflatoxin B < sub > 1 < /sub > detoxification potential of leaves extract of < em > Moringa oleifera < /em > and < em > Calotropis procera < /em >
Nat Prod Res. 2024 Apr 16:1-9. doi: 10.1080/14786419.2024.2342003. Online ahead of print.ABSTRACTThe present study aimed to identify the presence of certain classes of phytochemicals in the leaf extract of medicinal herbs viz. Moringa oleifera and Calotropis procera, using qualitative detection tests and explored the potential of aqueous and ethanolic extract to inhibit aflatoxin production by thin layer chromatography at 25 °C and pH (7) of different incubation times i.e. 0-, 1-, 3-, 6- and 24-h. Qualitative phytochemical analysis reported that the aqueous leave extracts of M. oleifera and C. procera contained tannins, p...
Source: Natural Product Research - April 16, 2024 Category: Biochemistry Authors: Nehrish Nisar Maryam Ajmal Nafeesa Qudsia Hanif Syed Waqas Hassan Source Type: research
Facile fabrication of new bioadsorbents from Moringa oleifera and alginate for efficient removal of uranium(VI)
This article presents the first study on the use of alginate and moringa as an effective adsorbent for uranium treatment under various conditions. A new method of preparing adsorbents was used by addingMoringa oleifera seeds (MOS) to alginate through simple grafting. The resulting beads have a heterogeneous, sponge-like structure that is reversible. The adsorbents were tested for their ability to remove uranium ions from water and showed excellent efficiency with an adsorption capacity of 443.60 mg/g for alginate-PEI-MOS and 341.38 mg/g for alginate-Glu-MOS. Additionally, these adsorbents showed an interesting rate of s...
Source: Journal of Radioanalytical and Nuclear Chemistry - April 16, 2024 Category: Nuclear Medicine Source Type: research
Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
Initiation of ART among people living with HIV (PLWH) having a CD4 count ≤ 350cells/µl, produces poor immunological recovery, putting them at a high risk of opportunistic infections. To mitigate this, PLWH on ... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 16, 2024 Category: Infectious Diseases Authors: Silvano S. Twinomujuni, Esther C Atukunda, Jackson K. Mukonzo, Musinguzi Nicholas, Felicitas Roelofsen and Patrick E. Ogwang Tags: Brief Report Source Type: research
Moringa oleifera and Its Biochemical Compounds: Potential Multi-targeted Therapeutic Agents Against COVID-19 and Associated Cancer Progression
Biochem Genet. 2024 Apr 7. doi: 10.1007/s10528-024-10758-w. Online ahead of print.ABSTRACTThe Coronavirus disease-2019 (COVID-19) pandemic is a global concern, with updated pharmacological therapeutic strategies needed. Cancer patients have been found to be more susceptible to severe COVID-19 and death, and COVID-19 can also lead to cancer progression. Traditional medicinal plants have long been used as anti-infection and anti-inflammatory agents, and Moringa oleifera (M. oleifera) is one such plant containing natural products such as kaempferol, quercetin, and hesperetin, which can reduce inflammatory responses and compli...
Source: Biochemical Genetics - April 7, 2024 Category: Genetics & Stem Cells Authors: Ali Yousefi Rad Ali Asghar Rastegari Kahin Shahanipour Ramesh Monajemi Source Type: research
Phyto-fabrication of Moringa oleifera peel-sourced silver nanoparticles: A promising approach for combating hepatic cancer by targeting proinflammatory cytokines and mitigating cytokine storms
This study focuses on the eco-friendly synthesis of silver nanoparticles infused with M. oleifera peel extract biomolecules and their impact on regulating proinflammatory cytokines, as well as their potential anticancer effects against Wistar rats. The freshly synthesized nanoformulation underwent comprehensive characterization, followed by antihepatic cancer evaluation using a diethyl nitrosamine-induced model (at a dose of 200 mg kg-1 BW). The study demonstrates a significant reduction in proinflammatory cytokines such as tumor necrosis factor-α, interleukin-6, interleukin-1β, and nuclear factor kappa beta (NF-kB). Fur...
Source: Chemistry and Biodiversity - April 7, 2024 Category: Biochemistry Authors: Shahnawaz Sameem Vivek Dwivedi Vikas Kumar Ashish R Dwivedi Prateek Pathak Bhupendra Singh Mashooq Ahmad Bhat Amita Verma Source Type: research
Neuromodulatory effects induced by the association of Moringa oleifera Lam., Tribulus terrestris L., Undaria pinnatidifida extracts in the hypothalamus
Chem Biodivers. 2024 Mar 25:e202302075. doi: 10.1002/cbdv.202302075. Online ahead of print.ABSTRACTThe present study investigated the role of a commercial formulation constituted by herbal extracts from Rhodiola rosea, Undaria pinnatifida, Tribulus terrestris, and Moringa oleifera. The formulation was analysed for determining the content in total phenols and flavonoids and scavenging/reducing properties. The formulation was also tested on isolated mouse hypothalamus in order to investigate effects on serotonin, dopamine, neuropeptide Y (NPY), and orexin A. The gene expression of gonadrotopin releasing hormone (GnRH) was al...
Source: Chemistry and Biodiversity - March 25, 2024 Category: Biochemistry Authors: Annalisa Chiavaroli Simonetta Cristina Di Simone Alessandra Acquaviva Nilofar Nilofar Maria Loreta Libero Luigi Brunetti Lucia Recinella Sheila Leone Giustino Orlando Gokhan Zengin Maura Di Vito Luigi Menghini Claudio Ferrante Source Type: research
Neuromodulatory effects induced by the association of Moringa oleifera Lam., Tribulus terrestris L., Undaria pinnatidifida extracts in the hypothalamus
Chem Biodivers. 2024 Mar 25:e202302075. doi: 10.1002/cbdv.202302075. Online ahead of print.ABSTRACTThe present study investigated the role of a commercial formulation constituted by herbal extracts from Rhodiola rosea, Undaria pinnatifida, Tribulus terrestris, and Moringa oleifera. The formulation was analysed for determining the content in total phenols and flavonoids and scavenging/reducing properties. The formulation was also tested on isolated mouse hypothalamus in order to investigate effects on serotonin, dopamine, neuropeptide Y (NPY), and orexin A. The gene expression of gonadrotopin releasing hormone (GnRH) was al...
Source: Chemistry and Biodiversity - March 25, 2024 Category: Biochemistry Authors: Annalisa Chiavaroli Simonetta Cristina Di Simone Alessandra Acquaviva Nilofar Nilofar Maria Loreta Libero Luigi Brunetti Lucia Recinella Sheila Leone Giustino Orlando Gokhan Zengin Maura Di Vito Luigi Menghini Claudio Ferrante Source Type: research
Impacts of microwave-assisted extraction parameters on total phenolic compounds yield from Algerian < em > Moringa oleifera < /em > leaves, using response surface methodology
Nat Prod Res. 2024 Mar 23:1-9. doi: 10.1080/14786419.2024.2333044. Online ahead of print.ABSTRACTThe study aimed to optimise the microwave-assisted extraction (MAE) of total phenolic compounds (TPC) from Moringa oleifera Lam. leaves using response surface methodology (RSM) and Box-Behnken designs (BBD). Factors such as ethanol concentration, microwave power, irradiation time, and solvent to solid ratio were assessed in single-factor tests. Under optimal extraction conditions (48.86% ethanol, 626.53 W microwave power, 99.48 s irradiation, 29.67 mL/g solvent to solid ratio and 21.12 W/mL power density), TPC was 58.45 ± 0.68...
Source: Natural Product Research - March 23, 2024 Category: Biochemistry Authors: Farida Kheyar Naoual Kheyar Malek Amiali Lila Boulekbache-Makhlouf Ahcene Kadi Ahmed Benchabane Arezki Bitam Source Type: research
Impacts of microwave-assisted extraction parameters on total phenolic compounds yield from Algerian < em > Moringa oleifera < /em > leaves, using response surface methodology
Nat Prod Res. 2024 Mar 23:1-9. doi: 10.1080/14786419.2024.2333044. Online ahead of print.ABSTRACTThe study aimed to optimise the microwave-assisted extraction (MAE) of total phenolic compounds (TPC) from Moringa oleifera Lam. leaves using response surface methodology (RSM) and Box-Behnken designs (BBD). Factors such as ethanol concentration, microwave power, irradiation time, and solvent to solid ratio were assessed in single-factor tests. Under optimal extraction conditions (48.86% ethanol, 626.53 W microwave power, 99.48 s irradiation, 29.67 mL/g solvent to solid ratio and 21.12 W/mL power density), TPC was 58.45 ± 0.68...
Source: Natural Product Research - March 23, 2024 Category: Biochemistry Authors: Farida Kheyar Naoual Kheyar Malek Amiali Lila Boulekbache-Makhlouf Ahcene Kadi Ahmed Benchabane Arezki Bitam Source Type: research
Molecules, Vol. 29, Pages 1380: Phytochemical Profiling by UHPLC & ndash;Q-TOF/MS and Chemopreventive Effect of Aqueous Extract of Moringa oleifera Leaves and Benzyl Isothiocyanate on Murine Mammary Carcinogenesis
In conclusion, this study suggests that both the aqueous extract of Moringa oleifera leaves and the benzyl isothiocyanate possess antitumor properties against mammary carcinogenesis, and this effect could be due, at least in part, to the flavonoids and isothiocyanates present in the extract. (Source: Molecules)
Source: Molecules - March 20, 2024 Category: Chemistry Authors: Juan Pedro Rojas-Armas Miriam Palomino-Pacheco Jorge Luis Arroyo-Acevedo Jos é Manuel Ortiz-Sánchez Hugo Jes ús Justil-Guerrero Jaime Teodocio Mart ínez-Heredia Am érico Castro-Luna Crescencio Rodr íguez Flores Aldo Javier Guzm án Duxtan Tags: Article Source Type: research
The effect of Channa striata, Moringa oleifera, and Curcuma xanthorrhiza extract on accelerating recovery in a ventilated patient with hemorrhagic shock grade 3 due to prolonged retained placenta: a case report
ConclusionThis is the first case report describing the effect ofC. striata,M. oleifera, andC. xanthorrhiza extract in a patient with severe hemorrhagic shock due to a prolonged placenta. Accelerated recovery showed the possibility benefit ofC. striata,M. oleifera, andC. xanthorrhiza extract in stabilizing oncotic pressure, neutralizing free radicals, and preventing further damage in hypoxic cells. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 19, 2024 Category: General Medicine Source Type: research
Modulatory effects of Moringa oleifera leaf extract on sodium nitrate-induced experimental colitis via regulation of P53, Ki-67 and PCNA biomarkers
CONCLUSION: MO protected the colonic mucosa against SN-induced changes regulating apoptosis, and cell proliferation.PMID:38493756 | DOI:10.1016/j.tice.2024.102327 (Source: Tissue and Cell)
Source: Tissue and Cell - March 17, 2024 Category: Cytology Authors: Hend M Hassan Wael M Elsaed Dina Elzeiny Ola Ali Habotta Elshimaa S Eleraky Eman Mohamed El Nashar Mansour Abdullah Alghamdi Rashid A Aldahhan Mohammed Attieh Alzahrani Ali Mohni Saleh Alamari Eman Hamza Source Type: research
Modulatory effects of Moringa oleifera leaf extract on sodium nitrate-induced experimental colitis via regulation of P53, Ki-67 and PCNA biomarkers
CONCLUSION: MO protected the colonic mucosa against SN-induced changes regulating apoptosis, and cell proliferation.PMID:38493756 | DOI:10.1016/j.tice.2024.102327 (Source: Tissue and Cell)
Source: Tissue and Cell - March 17, 2024 Category: Cytology Authors: Hend M Hassan Wael M Elsaed Dina Elzeiny Ola Ali Habotta Elshimaa S Eleraky Eman Mohamed El Nashar Mansour Abdullah Alghamdi Rashid A Aldahhan Mohammed Attieh Alzahrani Ali Mohni Saleh Alamari Eman Hamza Source Type: research
Molecules, Vol. 29, Pages 1297: The Indiscriminate Chemical Makeup of Secondary Metabolites Derived from Endophytes Harvested from Aloe barbadensis Miller in South Africa & rsquo;s Limpopo Region
Molecules, Vol. 29, Pages 1297: The Indiscriminate Chemical Makeup of Secondary Metabolites Derived from Endophytes Harvested from Aloe barbadensis Miller in South Africa’s Limpopo Region
Molecules doi: 10.3390/molecules29061297
Authors:
Mpho Mamphoka Nchabeleng
Thierry Youmbi Fonkui
Green Ezekiel
The efficacy of 23 bacterial isolates obtained from surface-sterilized stems and leaves of three medicinal plants (Aloe barbadensis Miller, Artemisia afra, and Moringa oleifera) was investigated in an endeavour to prevent the growth of Mycobacterium bovis using the cross-streak method. Endophytes were isolat...
Source: Molecules - March 14, 2024 Category: Chemistry Authors: Mpho Mamphoka Nchabeleng Thierry Youmbi Fonkui Green Ezekiel Tags: Article Source Type: research
Reversal of valproate-induced major salivary gland changes by moringa oleifera extract in rats
This study aimed to explore the potential protective impacts of Moringa oleifera extract on major alteration in salivary glands of rats exposed to sodium valproate (VA). Groups were defined as control, control + moringa extract, sodium valproate, and sodium valproate + moringa extract. Antioxidant and oxidant status, activities of digestive and metabolic enzymes were examined. VA treatment led to various biochemical changes in the salivary glands, including decreased levels of antioxidants like glutathione, glutathione-S-transferase, and superoxide dismutase (except for sublingual superoxide dismutase). Conversely, a decre...
Source: Chemistry and Biodiversity - March 12, 2024 Category: Biochemistry Authors: Eda Cergel Burcin Alev Tuzuner Ismet Burcu Turkyilmaz Sehkar Oktay Umar Faruk Magaji Ozlem Sacan Refiye Yanardag Aysen Yarat Source Type: research