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Miracle Tree ( Moringa oleifera ) Attuned GFAP and Synaptophysin Levels, Oxidative Stress and Biomarkers in Cerebellar Fluorosis of Pregnant Rats
Conclusion: Histological and ultrastructural examinations confirmed the recuperating effects of M. oleifera on mothers' cerebellar tissue intoxicated with fluoride indicated by intact folia and restored Purkinje cells number and architecture. The maternal study emphasized the anti-abortifacient activity of moringa against fluoride induced-fetotoxicity.PMID:38334155 | DOI:10.3923/pjbs.2023.628.650 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - February 9, 2024 Category: Biomedical Science Authors: Amira El-Helaly Amoura M Abou-El-Naga Khulud M Alshehri Mai Alaa El-Dein Source Type: research

Enhancement potential of Moringa oleifera leaves extract on buffalo bull cryopreserved semen quality and fertilization capacity
This study indicated that inclusion of MOLE to semen extender improved the quality and fertility of the post-thawed buffalo bulls' semen through enhancing the activities of the antioxidant enzyme system and decreasing cryodamage of the buffalo bull spermatozoa.PMID:38330533 | DOI:10.1016/j.anireprosci.2024.107414 (Source: Animal Reproduction Science)
Source: Animal Reproduction Science - February 8, 2024 Category: Zoology Authors: Dina Mahdy Shokry Magdy Ramadan Badr Abdel-Aziz Mustafa Sakr Ahmed Mohamed Elmesiry Mohamed Mahmoud Assy Zaher Rawash Mabrouk Attia Abd Eldaim Source Type: research

Bio-stimulants from medicinally and nutritionally significant plant extracts mitigate drought adversities in Zea mays through enhanced physiological, biochemical, and antioxidant activities
In conclusion, MLE, MBE, BLE, and ABE extracts exhibit significant potential for enhancing seedling establishment and growth in maize under both normal and water deficit conditions.PMID:38310727 | DOI:10.1016/j.plaphy.2024.108396 (Source: Physiological Research)
Source: Physiological Research - February 4, 2024 Category: Physiology Authors: Shiuly Bhowmick Gauri Rai Shashank Kumar Mishra Nikita Bisht Puneet Singh Chauhan Source Type: research

Moringa oleifera (drumstick tree) —nutraceutical, cosmetological and medicinal importance: a review
Moringa oleifera Lam. (Moringaceae) is a species of tree with an increasing utility, occurring naturally mainly in Pakistan and northern India. M. oleifera is currently cultivated in Africa, South America, Asia and the Middle East. The usage of its leaves, seed oil, bark, fruits, flowers and roots has positive opinions of FDA (American Food and Drug Administration), EFSA (European Food Safety Authority) and CosIng (Cosmetic Ingredients database). The chemical composition of M. oleifera is dominated by: proteins (consisting mainly of amino acids such as arginine or serine), fatty acids (omega-3 and omega-6), vitamins (vitam...
Source: Frontiers in Pharmacology - February 2, 2024 Category: Drugs & Pharmacology Source Type: research

Promising Influences of Moringa oleifera in Functional Foods against Metabolic Syndrome: A Comprehensive and Mechanistic Review
Endocr Metab Immune Disord Drug Targets. 2024 Jan 25. doi: 10.2174/0118715303269893231207071440. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is now considered a global issue with a growing financial and health impact. Numerous herbal alternatives have been examined and researched due to the ever-increasing demand for new medications to treat metabolic syndrome disorders. People have empirically employed Moringa oleifera (MO), a native plant to several Asian nations, for a variety of diseases. We sought to examine recent research on MO in MetS and its potential mechanism of action in the current review. Four dat...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - January 27, 2024 Category: Endocrinology Authors: Mohammad Masoumvand Elmira Ramezani Vafa Baradaran Rahimi Vahid Reza Askari Source Type: research

Promising Influences of Moringa oleifera in Functional Foods against Metabolic Syndrome: A Comprehensive and Mechanistic Review
Endocr Metab Immune Disord Drug Targets. 2024 Jan 25. doi: 10.2174/0118715303269893231207071440. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is now considered a global issue with a growing financial and health impact. Numerous herbal alternatives have been examined and researched due to the ever-increasing demand for new medications to treat metabolic syndrome disorders. People have empirically employed Moringa oleifera (MO), a native plant to several Asian nations, for a variety of diseases. We sought to examine recent research on MO in MetS and its potential mechanism of action in the current review. Four dat...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - January 27, 2024 Category: Drugs & Pharmacology Authors: Mohammad Masoumvand Elmira Ramezani Vafa Baradaran Rahimi Vahid Reza Askari Source Type: research

Effect of casein phosphopeptide-amorphous calcium phosphate, Riva Star, and Moringa oleifera-based nano-silver fluoride on caries affected dentin remineralization bonded to composite resin
CONCLUSIONS: Remineralization of CAD using modern regimes (CPP-ACP, NSF-MOLE, and CO2 laser + TF has the potential to be used to enhance the bond strength of CAD to composite restoration.PMID:38235895 | DOI:10.26355/eurrev_202401_34887 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - January 18, 2024 Category: Drugs & Pharmacology Authors: F Alkhudhairy A Maawadh T Almohareb Source Type: research

Spatial and temporal characterization of the rich fraction of plastid DNA present in the nuclear genome of Moringa oleifera reveals unanticipated complexity in NUPTs ´ formation
Beyond the massive amounts of DNA and genes transferred from the protoorganelle genome to the nucleus during the endosymbiotic event that gave rise to the plastids, stretches of plastid DNA of varying size are... (Source: BMC Genomics)
Source: BMC Genomics - January 15, 2024 Category: Genetics & Stem Cells Authors: Juan Pablo Marczuk-Rojas, Ang élica María Álamo-Sierra, Antonio Salmerón, Alfredo Alcayde, Viktor Isanbaev and Lorenzo Carretero-Paulet Tags: Research Source Type: research

Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies
AbstractDiabetes mellitus is a prevalent cause of mortality worldwide and can lead to several secondary issues, including DWs, which are caused by hyperglycemia, diabetic neuropathy, anemia, and ischemia. Roughly 15% of diabetic patient ’s experience complications related to DWs, with 25% at risk of lower limb amputations. A conventional management protocol is currently used for treating diabetic foot syndrome, which involves therapy using various substances, such as bFGF, pDGF, VEGF, EGF, IGF-I, TGF-β, skin substitutes, cytokin e stimulators, cytokine inhibitors, MMPs inhibitors, gene and stem cell therapies, ECM, and ...
Source: Inflammopharmacology - January 11, 2024 Category: Drugs & Pharmacology Source Type: research