Bridging the divide: unveiling mutual immunological pathways of cancer and pregnancy
AbstractThe juxtaposition of two seemingly disparate physiological phenomena within the human body —namely, cancer and pregnancy—may offer profound insights into the intricate interplay between malignancies and the immune system. Recent investigations have unveiled striking similarities between the pivotal processes underpinning fetal implantation and successful gestation and those governing tumor initiation and progression. Notably, a confluence of features has emerged, underscoring parallels between the microenvironment of tumors and the maternal–fetal interface. These shared attributes encompass establishing vascu...
Source: Inflammation Research - March 16, 2024 Category: Research Source Type: research
Blood lead levels in pregnant women and their newborn infants at an Indian teaching hospital
CONCLUSION: In this descriptive study, there was a significant amount of lead transferred from mother to baby through the placenta. All mothers were not exposed to lead-associated industry and most were housewives. This article may be viewed as an eye-opener for understanding the blood lead concentration during pregnancy to avoid abnormal birth outcomes. To minimize exposure to environmental lead, all possible measures should be undertaken.PMID:38482293 | PMC:PMC10931910 | DOI:10.4103/jfmpc.jfmpc_963_23 (Source: Primary Care)
Source: Primary Care - March 14, 2024 Category: Primary Care Authors: Mahesh C Sahu Mehta R Yogeshbhai Hina Oza Kuldip Upadhyay Kabita Chanania Sanghamitra Pati Source Type: research
Progestogens in women with threatened miscarriage or recurrent miscarriage: A meta ‐analysis
ConclusionsIn women at increased risk of pregnancy loss, progestogens probably increase live births without increasing adverse maternal and neonatal events. It remains possible that the benefit is restricted to those with prior miscarriages. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Authors: Yunli Zhao,
Rohan D'Souza,
Ya Gao,
Qiukui Hao,
Lucas Kallas ‐Silva,
Jeremy P. Steen,
Gordon Guyatt Tags: SYSTEMATIC REVIEW Source Type: research
Causal associations between Helicobacter pylori infection and pregnancy and neonatal outcomes: a two-sample Mendelian randomization study
ConclusionOur two-sample MR study demonstrated a causal relationship of H. pylori infection with preeclampsia-eclampsia and premature rupture of membranes. The findings confirm the epidemiological evidence on the adverse impact of H. pylori in pregnancy. Further studies are needed to elucidate the pathophysiological mechanisms and assess the effectiveness of pre-pregnancy screening and preventive eradication. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 14, 2024 Category: Microbiology Source Type: research
Maternal gut microbiota in the health of mothers and offspring: from the perspective of immunology
Due to the physiological alteration during pregnancy, maternal gut microbiota changes following the metabolic processes. Recent studies have revealed that maternal gut microbiota is closely associated with the immune microenvironment in utero during pregnancy and plays a vital role in specific pregnancy complications, including preeclampsia, gestational diabetes, preterm birth and recurrent miscarriages. Some other evidence has also shown that aberrant maternal gut microbiota increases the risk of various diseases in the offspring, such as allergic and neurodevelopmental disorders, through the immune alignment between moth...
Source: Frontiers in Immunology - March 13, 2024 Category: Allergy & Immunology Source Type: research
Live birth outcomes following single-step blastocyst warming technique – optimizing efficiency without impacting live birth rates
ConclusionsThe study found equivalent outcomes for SS and SW in all parameters except for a slight rise in the rate of multiple gestations. The results suggest that SS warming is an efficient, viable alternative to SW, reducing thaw times without adverse effects on live birth rates or neonatal birth weights. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - March 13, 2024 Category: Reproduction Medicine Source Type: research
(In)visibilising pregnancy loss in Southern Malawi
Cult Health Sex. 2024 Mar 12:1-16. doi: 10.1080/13691058.2024.2324001. Online ahead of print.ABSTRACTMiscarriages, stillbirths and neonatal deaths have received limited attention in global health programmes and research, even though pregnancy loss is common, traumatic and stigmatised. This paper seeks to illuminate lived experiences of pregnancy loss in southern Malawi, drawing on findings from semi-structured interviews and focus groups with women who have experienced loss, health professionals and community members, and observations of maternity care. Combining thematic and discourse analysis, we show how societal and me...
Source: Culture, Health and Sexuality - March 12, 2024 Category: International Medicine & Public Health Authors: Bregje de Kok Marion Chirwa Kajombo Priscilla Matinga Blessings Kaunda Source Type: research
(In)visibilising pregnancy loss in Southern Malawi
Cult Health Sex. 2024 Mar 12:1-16. doi: 10.1080/13691058.2024.2324001. Online ahead of print.ABSTRACTMiscarriages, stillbirths and neonatal deaths have received limited attention in global health programmes and research, even though pregnancy loss is common, traumatic and stigmatised. This paper seeks to illuminate lived experiences of pregnancy loss in southern Malawi, drawing on findings from semi-structured interviews and focus groups with women who have experienced loss, health professionals and community members, and observations of maternity care. Combining thematic and discourse analysis, we show how societal and me...
Source: Culture, Health and Sexuality - March 12, 2024 Category: International Medicine & Public Health Authors: Bregje de Kok Marion Chirwa Kajombo Priscilla Matinga Blessings Kaunda Source Type: research
A male fetus with cyclopia was discovered after miscarriage: A rare case report from Syria
Key Clinical MessageThis case of alobar holoprosencephaly and cyclopia emphasizes the value of prenatal check-ups, particularly in low-income countries. Early ultrasound diagnosis leads to early gestational termination, preventing psychological trauma for the parents.AbstractAlobar holoprosencephaly is a rare-occurrence malformation with a bad prognosis linked to cyclopia, the most severe cranial feature. Prenatal examinations are essential for identifying these deformities and preventing parental mental health damage. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 11, 2024 Category: General Medicine Authors: Tala Dakkak,
Marah Mansour,
Habib Jarbouh,
Abdolmoin Ktail Tags: CASE REPORT Source Type: research
Unlocking the potential of fondaparinux: guideline for optimal usage and clinical suggestions (2023)
Conclusion: The purpose of this guideline is to provide all healthcare providers with high-quality recommendations for the clinical use of fondaparinux and to improve the rational use of the drug in clinical practice. Currently, there is a lack of a dedicated antidote for the management of fondaparinux. The clinical investigation of activated prothrombin complex concentrate (APCC) or recombinant activated factor VII (rFⅦa) as potential reversal agents is still pending. This critical gap necessitates heightened scrutiny and research emphasis, potentially constituting a novel avenue for future inquiries into fondaparinux s...
Source: Frontiers in Pharmacology - March 11, 2024 Category: Drugs & Pharmacology Source Type: research
Safety monitoring of bivalent mRNA COVID-19 vaccine among pregnant persons in the vaccine adverse event reporting System - United States, September 1, 2022 - March 31, 2023
CONCLUSIONS: Based on this review of reports to VAERS, the safety profile of bivalent mRNA COVID-19 vaccination in pregnant persons was comparable to that observed for monovalent mRNA COVID-19 booster vaccination (3rd and 4th dose) in pregnant persons.PMID:38462432 | DOI:10.1016/j.vaccine.2024.02.084 (Source: Vaccine)
Source: Vaccine - March 10, 2024 Category: Allergy & Immunology Authors: Pedro L Moro Grace Carlock Nimita Fifadara Tei Habenicht Bicheng Zhang Penelope Strid Paige Marquez Source Type: research
Spiritual Support to Improve Women's Mental Health after Miscarriage and Stillbirth: A Qualitative Study in Japan
CONCLUSION: What women perceive as support after a miscarriage or stillbirth will be an important clue to care.PMID:38462460 | DOI:10.24546/0100486284 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - March 10, 2024 Category: General Medicine Authors: Yuko Endo Izumi Saito Source Type: research
Safety monitoring of bivalent mRNA COVID-19 vaccine among pregnant persons in the vaccine adverse event reporting System - United States, September 1, 2022 - March 31, 2023
CONCLUSIONS: Based on this review of reports to VAERS, the safety profile of bivalent mRNA COVID-19 vaccination in pregnant persons was comparable to that observed for monovalent mRNA COVID-19 booster vaccination (3rd and 4th dose) in pregnant persons.PMID:38462432 | DOI:10.1016/j.vaccine.2024.02.084 (Source: Vaccine)
Source: Vaccine - March 10, 2024 Category: Allergy & Immunology Authors: Pedro L Moro Grace Carlock Nimita Fifadara Tei Habenicht Bicheng Zhang Penelope Strid Paige Marquez Source Type: research
Spiritual Support to Improve Women's Mental Health after Miscarriage and Stillbirth: A Qualitative Study in Japan
CONCLUSION: What women perceive as support after a miscarriage or stillbirth will be an important clue to care.PMID:38462460 | DOI:10.24546/0100486284 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - March 10, 2024 Category: General Medicine Authors: Yuko Endo Izumi Saito Source Type: research
