Oral iron supplementation: new formulations, old questions
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.284967. Online ahead of print.ABSTRACTIron deficiency anemia and pre-anemic iron deficiency are the most frequent pathologies. The first line of treatment involves oral iron supplementation. The simplest, least expensive, and most frequently prescribed drug is ferrous sulfate, while other ferrous salts and ferric complexes with polysaccharides or succinylated milk proteins are also widely used. In recent years, novel iron formulations have been developed, such as the lipophilic iron donor ferric maltol, or nanoparticle encapsulated sucrosomial® iron. Oral iron supplem...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Kostas Pantopoulos Source Type: research
Maternal exposure to tributyltin alters the breast milk, hormonal profile, and thyroid morphology of dams and induces sex-specific changes in neonate rat offspring
Environ Pollut. 2024 Apr 13:123963. doi: 10.1016/j.envpol.2024.123963. Online ahead of print.ABSTRACTTributyltin (TBT) is the chemical substance commonly used worldwide to prevent biofouling of vessels. Due to its ability to bioaccumulate and biomagnify, even after being banned, significant concentrations of TBT can be detected in sediment, affecting marine and human life. Although studies have shown that direct exposure to TBT alters physiological parameters in mammals, the relationship between exposure to TBT during pregnancy and lactation, considered critical windows for metabolic programming, has not been fully elucida...
Source: Environmental Pollution - April 15, 2024 Category: Environmental Health Authors: Rosiane Aparecida Miranda Daniel Galinis Vieira Lima Luana Lopes de Souza Beatriz Souza da Silva Iala Milene Bertasso Lilian Guedes Meyer Camila L üdke Rossetti Reinaldo R öpke Junior Leandro Miranda-Alves Egberto Gaspar de Moura Patricia Cristina Lisbo Source Type: research
Enterovirus Infection in Preterm Quadruplets with Clinical Presentation of Neonatal Late-Onset Sepsis: a Case Report
Z Geburtshilfe Neonatol. 2024 Apr 15. doi: 10.1055/a-2279-6803. Online ahead of print.ABSTRACTThis is the unusual case of concurrent late-onset sepsis caused by enteroviruses in preterm quadruplets in a neonatal ward. While viral infections are an important differential diagnosis of bacterial sepsis in the outpatient setting, the occurrence in a neonatal ward with strict prophylactic hygiene measures is unusual. In this case, transmission of enteroviruses via breast milk appears possible.PMID:38621739 | DOI:10.1055/a-2279-6803 (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - April 15, 2024 Category: Perinatology & Neonatology Authors: Viktor Seifert Lena B öck Johannes Wirbelauer Source Type: research
Isolation and characterization of novel Staphylococcus aureus bacteriophage Hesat from dairy origin
Appl Microbiol Biotechnol. 2024 Apr 15;108(1):299. doi: 10.1007/s00253-024-13129-y.ABSTRACTA novel temperate phage, named Hesat, was isolated by the incubation of a dairy strain of Staphylococcus aureus belonging to spa-type t127 with either bovine or ovine milk. Hesat represents a new species of temperate phage within the Phietavirus genus of the Azeredovirinae subfamily. Its genome has a length of 43,129 bp and a GC content of 35.11% and contains 75 predicted ORFs, some of which linked to virulence. This includes (i) a pathogenicity island (SaPln2), homologous to the type II toxin-antitoxin system PemK/MazF family toxin;...
Source: Applied Microbiology and Biotechnology - April 15, 2024 Category: Microbiology Authors: Barbara Turchi Claudia Campobasso Arianna Nardinocchi Jeroen Wagemans Beatrice Torracca C édric Lood Graziano Di Giuseppe Paola Nieri Fabrizio Bertelloni Luca Turini Valeria Ruffo Rob Lavigne Mariagrazia Di Luca Source Type: research
Oral iron supplementation: new formulations, old questions
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.284967. Online ahead of print.ABSTRACTIron deficiency anemia and pre-anemic iron deficiency are the most frequent pathologies. The first line of treatment involves oral iron supplementation. The simplest, least expensive, and most frequently prescribed drug is ferrous sulfate, while other ferrous salts and ferric complexes with polysaccharides or succinylated milk proteins are also widely used. In recent years, novel iron formulations have been developed, such as the lipophilic iron donor ferric maltol, or nanoparticle encapsulated sucrosomial® iron. Oral iron supplem...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Kostas Pantopoulos Source Type: research
Enterovirus Infection in Preterm Quadruplets with Clinical Presentation of Neonatal Late-Onset Sepsis: a Case Report
Z Geburtshilfe Neonatol. 2024 Apr 15. doi: 10.1055/a-2279-6803. Online ahead of print.ABSTRACTThis is the unusual case of concurrent late-onset sepsis caused by enteroviruses in preterm quadruplets in a neonatal ward. While viral infections are an important differential diagnosis of bacterial sepsis in the outpatient setting, the occurrence in a neonatal ward with strict prophylactic hygiene measures is unusual. In this case, transmission of enteroviruses via breast milk appears possible.PMID:38621739 | DOI:10.1055/a-2279-6803 (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - April 15, 2024 Category: Perinatology & Neonatology Authors: Viktor Seifert Lena B öck Johannes Wirbelauer Source Type: research
Isolation and characterization of novel Staphylococcus aureus bacteriophage Hesat from dairy origin
Appl Microbiol Biotechnol. 2024 Apr 15;108(1):299. doi: 10.1007/s00253-024-13129-y.ABSTRACTA novel temperate phage, named Hesat, was isolated by the incubation of a dairy strain of Staphylococcus aureus belonging to spa-type t127 with either bovine or ovine milk. Hesat represents a new species of temperate phage within the Phietavirus genus of the Azeredovirinae subfamily. Its genome has a length of 43,129 bp and a GC content of 35.11% and contains 75 predicted ORFs, some of which linked to virulence. This includes (i) a pathogenicity island (SaPln2), homologous to the type II toxin-antitoxin system PemK/MazF family toxin;...
Source: Applied Microbiology and Biotechnology - April 15, 2024 Category: Microbiology Authors: Barbara Turchi Claudia Campobasso Arianna Nardinocchi Jeroen Wagemans Beatrice Torracca C édric Lood Graziano Di Giuseppe Paola Nieri Fabrizio Bertelloni Luca Turini Valeria Ruffo Rob Lavigne Mariagrazia Di Luca Source Type: research
Isolation and characterization of novel Staphylococcus aureus bacteriophage Hesat from dairy origin
Appl Microbiol Biotechnol. 2024 Apr 15;108(1):299. doi: 10.1007/s00253-024-13129-y.ABSTRACTA novel temperate phage, named Hesat, was isolated by the incubation of a dairy strain of Staphylococcus aureus belonging to spa-type t127 with either bovine or ovine milk. Hesat represents a new species of temperate phage within the Phietavirus genus of the Azeredovirinae subfamily. Its genome has a length of 43,129 bp and a GC content of 35.11% and contains 75 predicted ORFs, some of which linked to virulence. This includes (i) a pathogenicity island (SaPln2), homologous to the type II toxin-antitoxin system PemK/MazF family toxin;...
Source: Applied Microbiology and Biotechnology - April 15, 2024 Category: Microbiology Authors: Barbara Turchi Claudia Campobasso Arianna Nardinocchi Jeroen Wagemans Beatrice Torracca C édric Lood Graziano Di Giuseppe Paola Nieri Fabrizio Bertelloni Luca Turini Valeria Ruffo Rob Lavigne Mariagrazia Di Luca Source Type: research
Moderate low-cost modifications in diet prevent a substantial number of deaths and mitigate environmental impacts in Brazil
ConclusionA meaningful number of deaths can be avoided and environmental impacts reduced through moderate and potentially affordable diet modifications. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - April 15, 2024 Category: Nutrition Source Type: research
Molecules, Vol. 29, Pages 1795: The Fast Quantification of Vitamin B12 in Milk Powder by High-Performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry
This study presents a new technique for determining vitamin B12 in milk powder using high-performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS). We used ultrasonics with potassium ferrocyanide and zinc acetate solutions to extract the samples. 59Co was employed as the analytical target for cyanocobalamin. It was separated using a Phenomenex Luna 5 μm C18 (250 × 4.6 mm) chromatographic column with a mobile phase consisting of 1.6 mmol/L EDTA and 0.4 mmol/L KH2PO4 in a 60% v/v methanol solution (pH = 4.0). The sample has an excellent separating degree for free c...
Source: Molecules - April 15, 2024 Category: Chemistry Authors: Yang Zhou Zheng Tags: Article Source Type: research
Moderate low-cost modifications in diet prevent a substantial number of deaths and mitigate environmental impacts in Brazil
ConclusionA meaningful number of deaths can be avoided and environmental impacts reduced through moderate and potentially affordable diet modifications. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - April 15, 2024 Category: Nutrition Source Type: research
Foldable paper-based photoelectrochemical biosensor based on etching reaction of CoOOH nanosheets-coated laser-induced PbS/CdS/graphene for sensitive detection of ampicillin
Talanta. 2024 Apr 13;275:126085. doi: 10.1016/j.talanta.2024.126085. Online ahead of print.ABSTRACTTimely and rapid detection of antibiotic residues in the environment is conducive to safeguarding human health and promoting an ecological virtuous cycle. A foldable paper-based photoelectrochemical (PEC) sensor was successfully developed for the detection of ampicillin (AMP) based on glutathione/zirconium dioxide hollow nanorods/aptamer (GSH@ZrO2 HS@apt) modified cellulose paper as a reactive zone with laser direct-writing lead sulfide/cadmium sulfide/graphene (PbS/CdS/LIG) as photoelectrode and cobalt hydroxide (CoOOH) as a...
Source: Talanta - April 14, 2024 Category: Chemistry Authors: Zhenli Qiu Yufen Lei Xintong Lin Jinman Zhu Dianping Tang Yiting Chen Source Type: research
Pearl millet flour and green gram milk based probiotic beverage
Int J Food Microbiol. 2024 Apr 10;417:110696. doi: 10.1016/j.ijfoodmicro.2024.110696. Online ahead of print.ABSTRACTThe probiotic beverage was developed using germinated and ungerminated pearl millet flour and green gram milk. The germinated and ungerminated pearl millet flour was added to green gram milk at different concentrations (0.5-2.5 %) along with sugar and cardamom. The mixtures were then inoculated with probiotic bacteria Lactobacillus acidophilus incubated at 37 °C for 6 h. Characterization of probiotic beverages was carried out during storage at (4 ± 1)°C for 21 days. The germinated flour beverage had high a...
Source: International Journal of Food Microbiology - April 14, 2024 Category: Food Science Authors: Gargi Ghoshal Japneet Kamboj Prabhjot Kaur Source Type: research
Perinatal Exposure to Polychlorinated Biphenyls (PCBs) and Child Neurodevelopment: A Comprehensive Systematic Review of Outcomes and Methodological Approaches
CONCLUSIONS: Significant methodological, clinical and statistical heterogeneity existed in the included studies. Adverse effects on cognitive development and attention were observed in middle childhood. Inconclusive evidence prevailed regarding other neurodevelopmental aspects due to limited studies. Future research could further explore sex-specific associations and evaluate associations at lower exposure levels post-PCB ban in the US. It should also consider OH-PCB metabolites, co-pollutants, mixtures, and their potential interactions.PMID:38615789 | DOI:10.1016/j.envres.2024.118912 (Source: Environmental Research)
Source: Environmental Research - April 14, 2024 Category: Environmental Health Authors: Arin A Balalian Jeanette A Stingone Linda G Kahn Julie B Herbstman Richard I Graeve Steven D Stellman Pam Factor-Litvak Source Type: research
Robust superhydrophobic cotton fabric based on dual-sized silica particles with self-healing nature
Int J Biol Macromol. 2024 Apr 11:131437. doi: 10.1016/j.ijbiomac.2024.131437. Online ahead of print.ABSTRACTImproving the durability of wear-resistant superhydrophobic surfaces is crucial for their practical use. To tackle this, research is now delving into self-healing superhydrophobic surfaces. In our study, we developed superhydrophobic cotton fabrics by embedding nano-silica particles, micro-silica powder, and polydimethylsiloxane (PDMS) using a dipping method. This innovative design grants the SiO2/PDMS cotton fabric remarkable superhydrophobicity, reflected by a water contact angle of 155°. Moreover, the PDMS was st...
Source: International Journal of Biological Macromolecules - April 13, 2024 Category: Biochemistry Authors: Ting Li Yi Peng Jianlong Yang Hang You Source Type: research
