Changing clinical characteristics of pediatric inpatients with pneumonia during COVID-19 pandamic: a retrospective study
ConclusionsThe number of children hospitalized with pneumonia and incidence of common pathogen infections were both reduced, and that allergy and micronutrient status in children were also changed after the outbreak of the COVID-19 pandemic. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 23, 2024 Category: Pediatrics Source Type: research

Clinico-haematobiochemical and cardiac alterations in Trypanosoma evansi infected buffaloes of Andhra Pradesh, India
AbstractThe present research aimed to document the incidence, clinical signs, haematological, and serum biochemical alterations, as well as electrocardiography and echocardiography findings in 62 buffaloes (selected from a total of 240) infected withTrypanosoma evansi. The study spanned one year, from January 2022 to December 2022. Morphological identification ofTrypanosoma evansi was done by the presence of a centrally positioned nucleus with a small sub-terminal kinetoplast at the posterior position through microscopic examination of Giemsa stained peripheral blood smears. The incidence of trypanosomosis were determined ...
Source: Veterinary Research Communications - April 23, 2024 Category: Veterinary Research Source Type: research

Influence of an Early Human Milk Diet on the Duration of Parenteral Nutrition and Incidence of Late-Onset Sepsis in Very Low Birthweight (VLBW) Infants: A Systematic Review
Breastfeeding Medicine, Ahead of Print. (Source: Breastfeeding Medicine)
Source: Breastfeeding Medicine - April 23, 2024 Category: Perinatology & Neonatology Authors: Roisin Coyne William Hughes Helen Purtill Deirdre McGrath Colum P. Dunne Roy K. Philip Source Type: research

Human Breast Milk Exosomal miRNAs are Influenced by Premature Delivery and Affect Neurodevelopment
ConclusionThis study demonstrates that miRNA expression in breast milk exosomes can be influenced by preterm delivery, thereby potentially impacting neurodevelopment in preterm infants. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 22, 2024 Category: Food Science Authors: Ling Ma, Yanyan Huo, Qingyuan Tang, Xiulian Wang, Weiqin Wang, Dan Wu, Yicheng Li, Lingyan Chen, Shasha Wang, Yiwen Zhu, Wenli Wang, Yuan Liu, Nanjie Xu, Li Chen, Guangjun Yu, Jinjin Chen Tags: Research Article Source Type: research

Impact of Dysphoric Milk Ejection Reflex on Mental Health
Breastfeeding Medicine, Ahead of Print. (Source: Breastfeeding Medicine)
Source: Breastfeeding Medicine - April 22, 2024 Category: Perinatology & Neonatology Authors: Ayb üke Kacır Nalan Karabayir Ferhat Karademir Mine Ba şıbüyük Özlem Öcal Övgü Büke Demet Deniz Bilgin Source Type: research

Foraging animal origin food samples as passive indicators of dioxin-like POPs contamination in industry sites: Method development, characterisation and risk assessment
Chemosphere. 2024 Apr 19:142078. doi: 10.1016/j.chemosphere.2024.142078. Online ahead of print.ABSTRACTTitanium dioxide (TiO2) is an important industrial chemical, and studies suggest its major production route - the chloride process could lead to the generation of unintentional dl-POPs. However, no relevant studies assessed the occurrence of dl-POPs associated with TiO2 production in the industrial zones, which is mostly due to the ultra-trace level distribution of these compounds in environmental compartments. The present study explored the novel possibility of utilising foraging animal-origin foods as sensitive indicato...
Source: Chemosphere - April 21, 2024 Category: Chemistry Authors: Amala Varghese Kirankumar P S Ajay S V Prathish K P Source Type: research

Foraging animal origin food samples as passive indicators of dioxin-like POPs contamination in industry sites: Method development, characterisation and risk assessment
Chemosphere. 2024 Apr 19:142078. doi: 10.1016/j.chemosphere.2024.142078. Online ahead of print.ABSTRACTTitanium dioxide (TiO2) is an important industrial chemical, and studies suggest its major production route - the chloride process could lead to the generation of unintentional dl-POPs. However, no relevant studies assessed the occurrence of dl-POPs associated with TiO2 production in the industrial zones, which is mostly due to the ultra-trace level distribution of these compounds in environmental compartments. The present study explored the novel possibility of utilising foraging animal-origin foods as sensitive indicato...
Source: Chemosphere - April 21, 2024 Category: Chemistry Authors: Amala Varghese Kirankumar P S Ajay S V Prathish K P Source Type: research

O-linked glycosylations in human milk casein and major whey proteins during lactation
This study aimed to identify and analyze O-linked glycans in HM by high-throughput mass spectrometry. 184 longitudinal HM samples from 66 donors from day 3 and months 1, 2, and 3 postpartum were subjected to a post-translational modification specific enrichment-based strategy using TiO2 and ZrO2 beads for O-linked glycopeptide enrichment. β-CN was found to be a major O-linked glycoprotein, additionally, αS1-CN, κ-CN, lactotransferrin, and albumin also contained O-linked glycans. As glycosyltransferases and glycosidases are involved in assembling the glycans including O-linked glycosylations, these were further investiga...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Martin N ørmark Thesbjerg Katrine Overgaard Poulsen Julie Astono Nina Aagaard Poulsen Lotte Bach Larsen S øren Drud-Heydary Nielsen Allan Stensballe Ulrik Kr æmer Sundekilde Source Type: research

Goat milk exosomal microRNAs alleviate LPS-induced intestinal inflammation in mice
In this study, the protective effect of goat milk exosomes on LPS-induced intestinal inflammation was investigated using mouse intestinal inflammation model and IEC-6 cell inflammation model. Small RNA sequencing was used to analyze the miRNA expression profile of goat milk exosomes. In this study, C-Exo and M-Exo alleviated intestinal inflammation by reducing the LPS-induced release of proinflammatory cytokines, inhibiting the increase in the NLRP3 protein and the activation of the TLR4/NFκB signaling pathway. C-Exo has a more significant inhibitory effect on them, and better therapeutic efficacy than M-Exo. Notably, the...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Feng Gao Shenghui Wu Kang Zhang Zhiming Xu Fusheng Quan Source Type: research

Factors Determining Course of IgE-Mediated Cow ’s Milk Allergy
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - April 19, 2024 Category: Pediatrics Source Type: research

The Effect of Whey Protein Supplements on Acne Vulgaris among Male Adolescents and Young Adults: A Case-Control Study from North of Jordan
CONCLUSION: This case-control study provides evidence of a positive association between whey protein consumption and acne risk.PMID:38633058 | PMC:PMC11022506 | DOI:10.1155/2024/2158229 (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - April 18, 2024 Category: Dermatology Authors: Jihan Muhaidat Almutazballlah Qablan Faris Gharaibeh Ghaith H Albataineh Nour Abdo Diala Alshiyab Firas Al-Qarqaz Source Type: research

Selection of a Suitable Animal Model to Evaluate Secretion of Drugs in the Human Milk: A Systematic Approach
Xenobiotica. 2024 Apr 18:1-23. doi: 10.1080/00498254.2024.2345283. Online ahead of print.ABSTRACTLack of data on drug secretion in human milk is a concern for safe use of drugs during postpartum.Clinical studies are often difficult to perform; despite substantial improvements in computational methodologies such as physiologically based pharmacokinetic modelling, there is limited clinical data to validate such models for many drugs.Various factors that are likely to impact milk to plasma ratio were identified. A literature search was performed to gather available data on milk composition, total volume of milk produced per d...
Source: Xenobiotica - April 18, 2024 Category: Research Authors: Riya Nilkant Chintha Kathiresan Namrata Kumar Steve Caritis Imam H Shaik Raman Venkataramanan Source Type: research

The infant gut microbiota as the cornerstone for future gastrointestinal health
Adv Appl Microbiol. 2024;126:93-119. doi: 10.1016/bs.aambs.2024.02.001. Epub 2024 Feb 19.ABSTRACTThe early postnatal period represents a critical window of time for the establishment and maturation of the human gut microbiota. The gut microbiota undergoes dramatic developmental changes during the first year of life, being influenced by a variety of external factors, with diet being a major player. Indeed, the introduction of complementary feeding provides novel nutritive substrates and triggers a shift from milk-adapted gut microbiota toward an adult-like bacterial composition, which is characterized by an enhancement in d...
Source: Advances in Applied Microbiology - April 18, 2024 Category: Microbiology Authors: Chiara Tarracchini Christian Milani Gabriele Andrea Lugli Leonardo Mancabelli Francesca Turroni Douwe van Sinderen Marco Ventura Source Type: research

Bacterial proteome adaptation during fermentation in dairy environments
Food Microbiol. 2024 Aug;121:104514. doi: 10.1016/j.fm.2024.104514. Epub 2024 Mar 2.ABSTRACTThe enzymatic repertoire of starter cultures belonging to the Lactococcus genus determines various important characteristics of fermented dairy products but might change in response to the substantial environmental changes in the manufacturing process. Assessing bacterial proteome adaptation in dairy and other food environments is challenging due to the high matrix-protein concentration and is even further complicated in particularly cheese by the high fat concentrations, the semi-solid state of that matrix, and the non-growing stat...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Berdien van Olst Avis Nugroho Sjef Boeren Jacques Vervoort Herwig Bachmann Michiel Kleerebezem Source Type: research

Regulation of lactose, glucose and sucrose metabolisms in S. thermophilus
Food Microbiol. 2024 Aug;121:104487. doi: 10.1016/j.fm.2024.104487. Epub 2024 Feb 12.ABSTRACTStreptococcus thermophilus is a bacterium widely used in the production of yogurts and cheeses, where it efficiently ferments lactose, the saccharide naturally present in milk. It is also employed as a starter in dairy- or plant-based fermented foods that contain saccharides other than lactose (e.g., sucrose, glucose). However, little is known about how saccharide use is regulated, in particular when saccharides are mixed. Here, we determine the effect of the 5 sugars that S. thermophilus is able to use, at different concentration ...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: C Gasser J M Faurie F Rul Source Type: research