The infant gut microbiota as the cornerstone for future gastrointestinal health
Adv Appl Microbiol. 2024;126:93-119. doi: 10.1016/bs.aambs.2024.02.001. Epub 2024 Feb 19.ABSTRACTThe early postnatal period represents a critical window of time for the establishment and maturation of the human gut microbiota. The gut microbiota undergoes dramatic developmental changes during the first year of life, being influenced by a variety of external factors, with diet being a major player. Indeed, the introduction of complementary feeding provides novel nutritive substrates and triggers a shift from milk-adapted gut microbiota toward an adult-like bacterial composition, which is characterized by an enhancement in d...
Source: Advances in Applied Microbiology - April 18, 2024 Category: Microbiology Authors: Chiara Tarracchini Christian Milani Gabriele Andrea Lugli Leonardo Mancabelli Francesca Turroni Douwe van Sinderen Marco Ventura Source Type: research
Emerging Trends in Bioavailability and Pharma-Nutraceutical Potential of Whey Bioactives
J Nutr Metab. 2024 Apr 10;2024:8455666. doi: 10.1155/2024/8455666. eCollection 2024.ABSTRACTWhey, a component of milk and a useful by-product of the dairy industry's casein and cheese-making, has been used for generations to augment animal feed. It contains a range of proteins, including α-lactalbumin, β-lactoglobulin, bovine serum albumin, heavy and light chain immunoglobulins, lactoferrin, glycomacropeptide, and lactoperoxidase. Whey proteins exhibit great potential as biopolymers for creating bioactive delivery systems owing to their distinct health-enhancing characteristics and the presence of numerous amino acid gro...
Source: Journal of Nutrition and Metabolism - April 18, 2024 Category: Nutrition Authors: Adhithyan T Pillai Sonia Morya Ladislaus Manaku Kasankala Source Type: research
The Effect of Whey Protein Supplements on Acne Vulgaris among Male Adolescents and Young Adults: A Case-Control Study from North of Jordan
CONCLUSION: This case-control study provides evidence of a positive association between whey protein consumption and acne risk.PMID:38633058 | PMC:PMC11022506 | DOI:10.1155/2024/2158229 (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - April 18, 2024 Category: Dermatology Authors: Jihan Muhaidat Almutazballlah Qablan Faris Gharaibeh Ghaith H Albataineh Nour Abdo Diala Alshiyab Firas Al-Qarqaz Source Type: research
The infant gut microbiota as the cornerstone for future gastrointestinal health
Adv Appl Microbiol. 2024;126:93-119. doi: 10.1016/bs.aambs.2024.02.001. Epub 2024 Feb 19.ABSTRACTThe early postnatal period represents a critical window of time for the establishment and maturation of the human gut microbiota. The gut microbiota undergoes dramatic developmental changes during the first year of life, being influenced by a variety of external factors, with diet being a major player. Indeed, the introduction of complementary feeding provides novel nutritive substrates and triggers a shift from milk-adapted gut microbiota toward an adult-like bacterial composition, which is characterized by an enhancement in d...
Source: Advances in Applied Microbiology - April 18, 2024 Category: Microbiology Authors: Chiara Tarracchini Christian Milani Gabriele Andrea Lugli Leonardo Mancabelli Francesca Turroni Douwe van Sinderen Marco Ventura Source Type: research
Bacterial proteome adaptation during fermentation in dairy environments
Food Microbiol. 2024 Aug;121:104514. doi: 10.1016/j.fm.2024.104514. Epub 2024 Mar 2.ABSTRACTThe enzymatic repertoire of starter cultures belonging to the Lactococcus genus determines various important characteristics of fermented dairy products but might change in response to the substantial environmental changes in the manufacturing process. Assessing bacterial proteome adaptation in dairy and other food environments is challenging due to the high matrix-protein concentration and is even further complicated in particularly cheese by the high fat concentrations, the semi-solid state of that matrix, and the non-growing stat...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Berdien van Olst Avis Nugroho Sjef Boeren Jacques Vervoort Herwig Bachmann Michiel Kleerebezem Source Type: research
Regulation of lactose, glucose and sucrose metabolisms in S. thermophilus
Food Microbiol. 2024 Aug;121:104487. doi: 10.1016/j.fm.2024.104487. Epub 2024 Feb 12.ABSTRACTStreptococcus thermophilus is a bacterium widely used in the production of yogurts and cheeses, where it efficiently ferments lactose, the saccharide naturally present in milk. It is also employed as a starter in dairy- or plant-based fermented foods that contain saccharides other than lactose (e.g., sucrose, glucose). However, little is known about how saccharide use is regulated, in particular when saccharides are mixed. Here, we determine the effect of the 5 sugars that S. thermophilus is able to use, at different concentration ...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: C Gasser J M Faurie F Rul Source Type: research
Emerging Trends in Bioavailability and Pharma-Nutraceutical Potential of Whey Bioactives
J Nutr Metab. 2024 Apr 10;2024:8455666. doi: 10.1155/2024/8455666. eCollection 2024.ABSTRACTWhey, a component of milk and a useful by-product of the dairy industry's casein and cheese-making, has been used for generations to augment animal feed. It contains a range of proteins, including α-lactalbumin, β-lactoglobulin, bovine serum albumin, heavy and light chain immunoglobulins, lactoferrin, glycomacropeptide, and lactoperoxidase. Whey proteins exhibit great potential as biopolymers for creating bioactive delivery systems owing to their distinct health-enhancing characteristics and the presence of numerous amino acid gro...
Source: Journal of Nutrition and Metabolism - April 18, 2024 Category: Nutrition Authors: Adhithyan T Pillai Sonia Morya Ladislaus Manaku Kasankala Source Type: research
Enteral nutrition practices among very preterm infants in neonatal units: a cross-country comparative study
This study marks the first exploration of EN practices in neonatal units, examining their local and cross-country variations. It provides valuable insights to guide local trials and foster global collaboration among neonatal units to establish a unified knowledge base, standardized practices and promote research and innovation, ultimately contributing to optimal feeding practices for very preterm infants. (Source: Nutrition and Food Science)
Source: Nutrition and Food Science - April 18, 2024 Category: Nutrition Authors: Wesam Alyahya Rayhana AlSharfa Noor Alduhbaki Batool Al-Zahir Marwa Alqalaf Jumanah Alawfi Hussah Altwejri Hanoof Alessa Tunny Purayidathil Rabie Khattab Source Type: research
Effects of oropharyngeal administration of own mother's milk on oral microbial colonization in very low birth weight infants fed by gastric tube: A randomized controlled trial
DiscussionFrom birth to 21 days after birth, oropharyngeal mother's milk administration did not change the diversity and structural composition of the oral microbiota. The oral microbial diversity of infants declined significantly over time. Firmicutes had replaced Proteobacteria as the predominant phylum. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 18, 2024 Category: Allergy & Immunology Authors: Jie Liu,
Xiyang Zhang,
Qian Zhao,
Xiaohe Mu,
Chuanzhong Yang,
Yan Ning,
Xiaoyun Xiong,
Xiaoling Qin,
Lilian Chen Tags: ORIGINAL ARTICLE Source Type: research
Sensors, Vol. 24, Pages 2585: Development of a Two-Finger Haptic Robotic Hand with Novel Stiffness Detection and Impedance Control
Ahad Behboodi
Haptic hands and grippers, designed to enable skillful object manipulation, are pivotal for high-precision interaction with environments. These technologies are particularly vital in fields such as minimally invasive surgery, where they enhance surgical accuracy and tactile feedback: in the development of advanced prosthetic limbs, offering users improved functionality and a more natural sense of touch, and within industrial automation and manufacturing, they contribute to more efficient, safe, and flexible production processes. This paper presents the development of a two-finger robotic hand that employs...
Source: Sensors - April 18, 2024 Category: Biotechnology Authors: Vahid Mohammadi Ramin Shahbad Mojtaba Hosseini Mohammad Hossein Gholampour Saeed Shiry Ghidary Farshid Najafi Ahad Behboodi Tags: Article Source Type: research
Genes, Vol. 15, Pages 509: Research Progress and Applications of Bovine Genome in the Tribe Bovini
liu Zhang
Various bovine species have been domesticated and bred for thousands of years, and they provide adequate animal-derived products, including meat, milk, and leather, to meet human requirements. Despite the review studies on economic traits in cattle, the genetic basis of traits has only been partially explained by phenotype and pedigree breeding methods, due to the complexity of genomic regulation during animal development and growth. With the advent of next-generation sequencing technology, genomics projects, such as the 1000 Bull Genomes Project, Functional Annotation of Animal Genomes project, and Bovine Pa...
Source: Genes - April 18, 2024 Category: Genetics & Stem Cells Authors: Xingjie Du Yu Sun Tong Fu Tengyun Gao Tianliu Zhang Tags: Review Source Type: research
Chlordiazepoxide against signalling, receptor and regulatory proteins of breast cancer: a structure-based in-silico approach
In this study, we included four crucial proteins that perform signalling, receptor, and regulatory action, namely- NUDIX Hydrolases, Dihydrofolate Reductase, HER2/neu Kinase and EGFR and performed multitargeted molecular docking studies against human-approved drugs using HTVS, SP and extra precise algorithms and filtered the poses with MM\GBSA, suggested a benzodiazepine derivative chlordiazepoxide, used as an anxiolytic agent, can be a multitargeted inhibitor with docking and MM\GBSA score ranging from - 4.628 to - 7.877 and - 18.59 to - 135.86 kcal/mol, respectively, and the most interacted residues were 6ARG, 6GLU, 3TRP...
Source: Molecular Medicine - April 17, 2024 Category: Molecular Biology Authors: Ahad Amer Alsaiari Amal F Gharib Maha Mahfouz Bakhuraysah Amani A Alrehaili Shatha M Algethami Hayfa Ali Alsaif Norah Al Harthi Mohammed Ageeli Hakami Source Type: research
Lipase and Protease Production Ability of Multi-drug Resistant Bacteria Worsens the Outcomes of Wound Infections
CONCLUSION: In conclusion, the findings suggest that lipases and proteases produced by bacteria could contribute to drug resistance and act as virulence factors in the development of surgical site infections. Understanding the role of these enzymes may inform strategies for preventing and managing post-surgical wound infections more effectively.PMID:38629357 | DOI:10.2174/0113816128302189240402043330 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - April 17, 2024 Category: Drugs & Pharmacology Authors: Attaur Rahman Saiqa Sardar Zeeshan Niaz Asif Khan None Sheheryar Abdulwahed Fahad Alrefaei Muhammad Hamayun Sajid Ali Source Type: research
Chlordiazepoxide against signalling, receptor and regulatory proteins of breast cancer: a structure-based in-silico approach
In this study, we included four crucial proteins that perform signalling, receptor, and regulatory action, namely- NUDIX Hydrolases, Dihydrofolate Reductase, HER2/neu Kinase and EGFR and performed multitargeted molecular docking studies against human-approved drugs using HTVS, SP and extra precise algorithms and filtered the poses with MM\GBSA, suggested a benzodiazepine derivative chlordiazepoxide, used as an anxiolytic agent, can be a multitargeted inhibitor with docking and MM\GBSA score ranging from - 4.628 to - 7.877 and - 18.59 to - 135.86 kcal/mol, respectively, and the most interacted residues were 6ARG, 6GLU, 3TRP...
Source: Molecular Medicine - April 17, 2024 Category: Molecular Biology Authors: Ahad Amer Alsaiari Amal F Gharib Maha Mahfouz Bakhuraysah Amani A Alrehaili Shatha M Algethami Hayfa Ali Alsaif Norah Al Harthi Mohammed Ageeli Hakami Source Type: research
Lipase and Protease Production Ability of Multi-drug Resistant Bacteria Worsens the Outcomes of Wound Infections
CONCLUSION: In conclusion, the findings suggest that lipases and proteases produced by bacteria could contribute to drug resistance and act as virulence factors in the development of surgical site infections. Understanding the role of these enzymes may inform strategies for preventing and managing post-surgical wound infections more effectively.PMID:38629357 | DOI:10.2174/0113816128302189240402043330 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - April 17, 2024 Category: Drugs & Pharmacology Authors: Attaur Rahman Saiqa Sardar Zeeshan Niaz Asif Khan None Sheheryar Abdulwahed Fahad Alrefaei Muhammad Hamayun Sajid Ali Source Type: research
