Fight Aging! Newsletter, April 22nd 2024
This study reveals a potential treatment for human mitochondrial diseases. « Back to Top A Population Study Correlates Air Pollution with Faster Cognitive Aging https://www.fightaging.org/archives/2024/04/a-population-study-correlates-air-pollution-with-faster-cognitive-aging/ A number of large epidemiological studies provide evidence for long-term exposure to greater levels of air pollution to accelerate the onset and progression of age-related disease. A few of these manage to control for the tendency for wealthier people to avoid living in areas with higher particulate air pollution, ...
Source: Fight Aging! - April 21, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Science Snippet: Breaking Down Biodegradability
Have you ever noticed plastic utensils or paper plates labeled as “biodegradable” and wondered what that meant? Materials are biodegradable when microorganisms such as bacteria can break them down into their building blocks. Biodegradable Plastics Plastic is everywhere: Milk jugs, grocery bags, and takeout containers are just a few examples. There are many types of plastic, but they’re all made up of long chains of repeating subunits called polymers. These polymers are designed to be durable and resistant to factors like heat, sunlight, and water, which makes them useful in a variety of situations. Toget...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 17, 2024 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology STEM Education Bacteria Science Snippet Source Type: blogs

Higher Taurine Intake in the Diet Correlates with Some Measures of Strength in Middle Age
Taurine is a amino acid mainly found in fish and meat in the diet. It is not an essential amino acid, and can be synthesized in humans. Circulating taurine levels in the bloodstream decline with age by about 50% by middle age for reasons that have yet to be determined. Studies in aged mice and non-human primates have shown modestly improved function and slowed aging following taurine supplementation. Past human studies of taurine supplementation have produced entirely unimpressive outcomes, but given that they predated present aging clocks it may be that the researchers were evaluating the wrong metrics. Taurine may act on...
Source: Fight Aging! - April 16, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

How can Warfarin be safe “ even in ” first trimester of pregnancy ? The story behind the 5 mg cut-off !
The well known pro-coagulant state of pregnancy is an evolutionary protective process to make blood clot quicker, to save fetal loss in early pregnancy and mitigate postpartum bleeding. Still, in many women, this natural adaptive process confers an enhanced thrombotic risk. The molecular mechanisms for this pro-coagulant state are, there is increased factor VII, fibrinogen, reduced protein S. It is interesting to note, while plasminogen levels are elevated, D-dimer is also increased, indicating an ongoing fight between pro & anticoagulant forces, converting the physiological maternal- placental bed a mini harmless DIC ...
Source: Dr.S.Venkatesan MD - March 20, 2024 Category: Cardiology Authors: dr s venkatesan Tags: cardiology -pregnancy Pregnancy and heart pregnancy and heart disease Uncategorized carpreg registry zahara esc acc guidelines on pregnancy and heart disease first trmestr use of oac warfarin heparin switch over lmwh bridge in pregnancy Source Type: blogs

Fight Aging! Newsletter, March 4th 2024
In conclusion, HSV (but not CMV) infection may be indicative of doubled dementia risk. « Back to Top Increased Dietary Leucine Activates mTOR Signaling in Macrophages, Accelerating Atherosclerosis https://www.fightaging.org/archives/2024/02/increased-dietary-leucine-activates-mtor-signaling-in-macrophages-accelerating-atherosclerosis/ Leucine is an essential amino acid, only obtained from the diet rather than synthesized by our cells. Leucine supplementation has been proposed as a way to slow the loss of muscle mass with age, as leucine processing becomes dysregulated with aging in a way...
Source: Fight Aging! - March 3, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Hamilton Beach Brands Holding Company Announces Acquisition of HealthBeacon PLC
Hamilton Beach Brands Holding Company today announced that, through its Hamilton Beach Health subsidiary, it has acquired HealthBeacon PLC, a medical technology firm and strategic partner of the company. HealthBeacon develops connected devices that enable patients with chronic conditions to manage their injectable medication regimens at home and provides other health services. Gregory H. Trepp, President and Chief Executive Officer at Hamilton Beach Brands Holding Company, said, “This acquisition is a key step in support of our strategic initiative to expand in the fast-growing home health and wellness market, and it...
Source: EMR and HIPAA - February 27, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Gregory H. Trepp Hamilton Beach Brands Holding Company Hamilton Beach Health Health IT Acquisitions HealthBeacon PLC Healthcare M&A Kieran Daly Rob George Source Type: blogs

Increased Dietary Leucine Activates mTOR Signaling in Macrophages, Accelerating Atherosclerosis
Leucine is an essential amino acid, only obtained from the diet rather than synthesized by our cells. Leucine supplementation has been proposed as a way to slow the loss of muscle mass with age, as leucine processing becomes dysregulated with aging in a way that can be compensated for by adding more leucine to the diet. Whether this actually works is a matter for debate; the evidence is mixed. The question is never whether the mechanism exists, the question is whether it has a large enough effect size to matter. Given this impetus for a greater intake of dietary leucine in later life, it is interesting to see the re...
Source: Fight Aging! - February 26, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The inflection point
Okay, pretty correct answers from our two commenters on the previous post. Not just chlorination, but clean water generally, i.e. sewage treatment and separating sewage from drinking water sources. Also pasteurization of milk was very important. But the story is a bit more complicated. Pre-industrial people were mostly rural, obviously drank their milk fresh and didn ' t have a lot to fear from waterborne diseases since their population was sparse. Obviously they did suffer greatly from other plagues -- the Black Death killed something like half the population of Europe in the mid-14th Century, and plague recurred in lesse...
Source: Stayin' Alive - February 20, 2024 Category: American Health Source Type: blogs

Decoding digestive discomfort: the science behind FODMAPs
FODMAPs are Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols. Digestive discomfort – excessive flatulence, “bloating”, loose stool, or constipation – is a prevalent issue for many, and it often finds its roots in a group of fermentable carbohydrates collectively known as FODMAPs. Understanding the science behind FODMAPs could help in establishing a more comfortable and gratifying relationship with food. In the realm of our digestive system, envision a system akin to an intricate ecosystem, teeming with activity. Various nutrients act as its constituents, powering this intern...
Source: David Bradley Sciencebase - Songs, Snaps, Science - February 5, 2024 Category: Science Authors: David Bradley Tags: Food Health and Medicine Source Type: blogs

The Astonishing Way To Lose Weight Twice As Fast With Milk And This Vitamin
As many as 50 percent of the world's population are deficient in this vitamin. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 4, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Weight Loss Source Type: blogs

Vegan Dairy: How the FDA Can Avoid Crying Over Spilled (Cow-Less) Milk
Keith Topper (St. John ’s University), Vegan Dairy: How the FDA Can Avoid Crying Over Spilled (Cow-Less) Milk, 79 Food and Drug L. J. (forthcoming 2023): A food product designation of vegan has always inherently implied a classification of dairy-free; however,... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - October 19, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Wednesday Bible Study: Job finally shuts up
 Yep. He spends the next three chapters saying, endlessly, the following:I used to be riding high, fortunate and admired, benevolent and generous.Now I ' m in the pits.If I ' d done anything wrong I could understand it.  And then, thank God, " The words of Job are ended. " It ' s long past time for this guy to STFU.29 And Job again took up his discourse, and said:2 “Oh, that I were as in the months of old,    as in the days when God watched over me;3 when his lamp shone upon my head,    and by his light I walked through darkness;4 as I was in my a...
Source: Stayin' Alive - October 18, 2023 Category: American Health Source Type: blogs

A Mental Sign of Vitamin B12 Deficiency
Vitamin B12 is relatively high in foods including fish, poultry, eggs and low-fat milk. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - September 17, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Nutrition Source Type: blogs

What Happens to Medicine in Your Body?
Medicines administered orally, by inhaler, and intravenously enter the stomach, lungs, and veins, respectively. They’re absorbed, then circulate throughout the body in the blood, are processed by the liver, and excreted by the kidneys and intestines. Credit: NIGMS. Have you ever wondered what happens inside your body when you take a medicine? An area of pharmacology called pharmacokinetics is the study of precisely that. Here, we follow a medicine as it enters the body, finds its therapeutic target (also called the active site), and then eventually leaves the body. To begin, a person takes or is given a dose of medi...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 11, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Common questions Medicines Miniseries Source Type: blogs

Sunday Sermonette: Job talks back
In Chapter 10, Job complains to God about the injustice done to him, and yearns again for death. Satan doesn ' t win the bet -- Job doesn ' t curse God or renounce him. But he walks right up to the edge. He wants an explanation. We ' ll see if he gets one.10 “I loathe my very life;    therefore I will give free rein to my complaint    and speak out in the bitterness of my soul.2 I say to God: Do not declare me guilty,    but tell me what charges you have against me.3 Does it please you to oppress me,    to spurn the work of you...
Source: Stayin' Alive - September 10, 2023 Category: American Health Source Type: blogs