Post molar choriocarcinoma with solitary renal metastasis in the absence of primary uterine tumor: a case report and review of the literature
ConclusionsUrological symptoms such as hematuria or spontaneous renal hemorrhage might be the only presentation of post molar choriocarcinoma with renal involvement. Thus, it can be beneficial to measure serum beta human chorionic gonadotropin levels among females of childbearing age who present with unexplained urological symptoms, especially if there is a history of prior hydatiform mole. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 30, 2024 Category: General Medicine Source Type: research
Effect of Single and Multiple Methotrexate Doses Treatment on Ovarian Reserve in Ectopic Pregnancy Women: A Prospective Cohort Study
ConclusionAdministration of MTX (regardless of number of doses) has no negative effect on ovarian reserve and is safe to be used as a treatment for EP. (Source: The Journal of Obstetrics and Gynecology of India)
Source: The Journal of Obstetrics and Gynecology of India - March 30, 2024 Category: OBGYN Source Type: research
When should the use of biological agents be considered in persistent oligoarticular juvenile idiopathic arthritis patients?
Conclusion: JADAS10 indicating ongoing severe disease activity at 3rd and 6th months rather than baseline JADAS10 is associated with the addition of bDMARDs.What is Known:• Oligoarticular JIA patients have the best outcomes among JIA categories and respond favorably to first-line therapies such as non-steroidal anti-inflammatory drugs and intraarticular corticosteroid injections.• Clinically inactive disease rates have increased with the widespread use of biological agents in oligoarticular JIA patients who have not responded to initial therapies.What is New:• Approximately one-fifth of patients with persistent oligo...
Source: European Journal of Pediatrics - March 30, 2024 Category: Pediatrics Source Type: research
Retracted: Clinical Efficacy of Methotrexate Combined with Iguratimod on Patients with Rheumatoid Arthritis and Its Influence on the Expression Levels of HOTAIR in Serum
Biomed Res Int. 2024 Mar 20;2024:9823071. doi: 10.1155/2024/9823071. eCollection 2024.ABSTRACT[This retracts the article DOI: 10.1155/2021/2486617.].PMID:38550190 | PMC:PMC10973261 | DOI:10.1155/2024/9823071 (Source: Biomed Res)
Source: Biomed Res - March 29, 2024 Category: Research Authors: BioMed Research International Source Type: research
Retracted: Clinical Efficacy of Methotrexate Combined with Iguratimod on Patients with Rheumatoid Arthritis and Its Influence on the Expression Levels of HOTAIR in Serum
Biomed Res Int. 2024 Mar 20;2024:9823071. doi: 10.1155/2024/9823071. eCollection 2024.ABSTRACT[This retracts the article DOI: 10.1155/2021/2486617.].PMID:38550190 | PMC:PMC10973261 | DOI:10.1155/2024/9823071 (Source: Biomed Res)
Source: Biomed Res - March 29, 2024 Category: Research Authors: BioMed Research International Source Type: research
Multiple Sclerosis-Associated Uveitis: A Case Report of Refractory Bilateral Chronic Granulomatous Panuveitis Successfully Treated with Tocilizumab
CONCLUSIONS: Tocilizumab appears to be an efficient option for managing uveitis associated with MS and may be a valuable choice for clinicians dealing with such cases.PMID:38546424 | DOI:10.1080/09273948.2024.2332783 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 28, 2024 Category: Allergy & Immunology Authors: William Gil Hassan Lagrib Louis Olagne C éline Tilignac Maud Perie Fr édéric Taithe Xavier Moisset Frederic Chiambaretta Pierre Clavelou Marc Andre Ludovic Trefond Source Type: research
Controlled Release of Drugs from Extracellular Matrix-Derived Peptide-Based Nanovesicles through Tailored Noncovalent Interactions
This study provides important insights into the drug delivery potential of ECnVs and offers useful information for future development of ECnV-based drug delivery systems for the treatment of various diseases.PMID:38546162 | DOI:10.1021/acs.biomac.3c01361 (Source: Biomacromolecules)
Source: Biomacromolecules - March 28, 2024 Category: Biochemistry Authors: Haofu Huang Jeongmin Hwang Sudha Anilkumar Kristi L Kiick Source Type: research
Development of pH-Sensitive Nanoparticle Incorporated into Dissolving Microarray Patch for Selective Delivery of Methotrexate
CONCLUSION: The developed SNP-DMAP-MTX has been proven to deliver MTX transdermal and selectively at the RA site, potentially avoiding conventional MTX side effects and enhancing the effectiveness of RA therapy.PMID:38538953 | DOI:10.1208/s12249-024-02777-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Nur Qadri Febrianti Anugerah Yaumil Ramadhani Aziz Muhamad Gilang Ramadhan Tunggeng Indianty Dwi Ramadhany Nur Syafika Sumayya Binti Abd Azis Yulia Yusrini Djabir Rangga Meidianto Asri Andi Dian Permana Source Type: research
Dilatation and Curettage after Uterine Artery Embolization versus Methotrexate Injection for the Treatment of Cesarean Scar Pregnancy: A Single-Center Experience
Conclusions: In our experience, administration of MTX is not recommended as the primary treatment or pre-treatment. Dilatation and curettage after uterine artery embolization are better than methotrexate injection for the treatment of cesarean scar pregnancy in a single-institution series in terms of complete recovery and length of hospital stay.PMID:38541213 | DOI:10.3390/medicina60030487 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Basilio Pecorino Giuseppe Scibilia Bianca Mignosa Maria Cristina Teodoro Benito Chiofalo Paolo Scollo Source Type: research
Multiple Sclerosis-Associated Uveitis: A Case Report of Refractory Bilateral Chronic Granulomatous Panuveitis Successfully Treated with Tocilizumab
CONCLUSIONS: Tocilizumab appears to be an efficient option for managing uveitis associated with MS and may be a valuable choice for clinicians dealing with such cases.PMID:38546424 | DOI:10.1080/09273948.2024.2332783 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 28, 2024 Category: Allergy & Immunology Authors: William Gil Hassan Lagrib Louis Olagne C éline Tilignac Maud Perie Fr édéric Taithe Xavier Moisset Frederic Chiambaretta Pierre Clavelou Marc Andre Ludovic Trefond Source Type: research
Controlled Release of Drugs from Extracellular Matrix-Derived Peptide-Based Nanovesicles through Tailored Noncovalent Interactions
This study provides important insights into the drug delivery potential of ECnVs and offers useful information for future development of ECnV-based drug delivery systems for the treatment of various diseases.PMID:38546162 | DOI:10.1021/acs.biomac.3c01361 (Source: Biomacromolecules)
Source: Biomacromolecules - March 28, 2024 Category: Biochemistry Authors: Haofu Huang Jeongmin Hwang Sudha Anilkumar Kristi L Kiick Source Type: research
Development of pH-Sensitive Nanoparticle Incorporated into Dissolving Microarray Patch for Selective Delivery of Methotrexate
CONCLUSION: The developed SNP-DMAP-MTX has been proven to deliver MTX transdermal and selectively at the RA site, potentially avoiding conventional MTX side effects and enhancing the effectiveness of RA therapy.PMID:38538953 | DOI:10.1208/s12249-024-02777-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Nur Qadri Febrianti Anugerah Yaumil Ramadhani Aziz Muhamad Gilang Ramadhan Tunggeng Indianty Dwi Ramadhany Nur Syafika Sumayya Binti Abd Azis Yulia Yusrini Djabir Rangga Meidianto Asri Andi Dian Permana Source Type: research
Dilatation and Curettage after Uterine Artery Embolization versus Methotrexate Injection for the Treatment of Cesarean Scar Pregnancy: A Single-Center Experience
Conclusions: In our experience, administration of MTX is not recommended as the primary treatment or pre-treatment. Dilatation and curettage after uterine artery embolization are better than methotrexate injection for the treatment of cesarean scar pregnancy in a single-institution series in terms of complete recovery and length of hospital stay.PMID:38541213 | PMC:PMC10971887 | DOI:10.3390/medicina60030487 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Basilio Pecorino Giuseppe Scibilia Bianca Mignosa Maria Cristina Teodoro Benito Chiofalo Paolo Scollo Source Type: research
Multiple Sclerosis-Associated Uveitis: A Case Report of Refractory Bilateral Chronic Granulomatous Panuveitis Successfully Treated with Tocilizumab
CONCLUSIONS: Tocilizumab appears to be an efficient option for managing uveitis associated with MS and may be a valuable choice for clinicians dealing with such cases.PMID:38546424 | DOI:10.1080/09273948.2024.2332783 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 28, 2024 Category: Allergy & Immunology Authors: William Gil Hassan Lagrib Louis Olagne C éline Tilignac Maud Perie Fr édéric Taithe Xavier Moisset Frederic Chiambaretta Pierre Clavelou Marc Andre Ludovic Trefond Source Type: research
Development of pH-Sensitive Nanoparticle Incorporated into Dissolving Microarray Patch for Selective Delivery of Methotrexate
CONCLUSION: The developed SNP-DMAP-MTX has been proven to deliver MTX transdermal and selectively at the RA site, potentially avoiding conventional MTX side effects and enhancing the effectiveness of RA therapy.PMID:38538953 | DOI:10.1208/s12249-024-02777-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Nur Qadri Febrianti Anugerah Yaumil Ramadhani Aziz Muhamad Gilang Ramadhan Tunggeng Indianty Dwi Ramadhany Nur Syafika Sumayya Binti Abd Azis Yulia Yusrini Djabir Rangga Meidianto Asri Andi Dian Permana Source Type: research
