Development of pH-Sensitive Nanoparticle Incorporated into Dissolving Microarray Patch for Selective Delivery of Methotrexate

CONCLUSION: The developed SNP-DMAP-MTX has been proven to deliver MTX transdermal and selectively at the RA site, potentially avoiding conventional MTX side effects and enhancing the effectiveness of RA therapy.PMID:38538953 | DOI:10.1208/s12249-024-02777-y
Source: AAPS PharmSciTech - Category: Drugs & Pharmacology Authors: Source Type: research