BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

BSL-4 facility and New virus research in Japan
Uirusu. 2022;72(1):1-6. doi: 10.2222/jsv.72.1.ABSTRACTViral hemorrhagic fevers such as Ebola virus disease, Marburg disease, Lassa fever, and Crimean-Congo hemorrhagic fever are infectious diseases that can cause severe, life-threatening illness. At present, there are only few licensed vaccines and antiviral drugs for these viral hemorrhagic fevers. The viruses which cause these viral hemorrhagic fevers are classified as BSL-4 pathogens and can be handled only in BSL-4 containment laboratories. Therefore, to develop the vaccines and treatments for these diseases, BSL-4 facility is essential. However, the BSL-4 facility ava...
Source: Uirusu. Journal of Virology - October 29, 2023 Category: Virology Authors: Jiro Yasuda Source Type: research

Micro ‒Global Positioning Systems for Identifying Nightly Opportunities for Marburg Virus Spillover to Humans by Egyptian Rousette Bats
Emerg Infect Dis. 2023 Nov;29(11):2238-2245. doi: 10.3201/eid2911.230362.ABSTRACTMarburg virus disease, caused by Marburg and Ravn orthomarburgviruses, emerges sporadically in sub-Saharan Africa and is often fatal in humans. The natural reservoir is the Egyptian rousette bat (ERB), which sheds virus in saliva, urine, and feces. Frugivorous ERBs discard test-bitten and partially eaten fruit, potentially leaving infectious virus behind that could be consumed by other susceptible animals or humans. Historically, 8 of 17 known Marburg virus disease outbreaks have been linked to human encroachment on ERB habitats, but no linkag...
Source: Emerging Infectious Diseases - October 25, 2023 Category: Infectious Diseases Authors: Brian R Amman Amy J Schuh Gloria Akurut Kilama Kamugisha Dianah Namanya Tara K Sealy James C Graziano Eric Enyel Emily A Wright Stephen Balinandi Julius J Lutwama Rebekah C Kading Patrick Atimnedi Jonathan S Towner Source Type: research

Micro ‒Global Positioning Systems for Identifying Nightly Opportunities for Marburg Virus Spillover to Humans by Egyptian Rousette Bats
Emerg Infect Dis. 2023 Nov;29(11):2238-2245. doi: 10.3201/eid2911.230362.ABSTRACTMarburg virus disease, caused by Marburg and Ravn orthomarburgviruses, emerges sporadically in sub-Saharan Africa and is often fatal in humans. The natural reservoir is the Egyptian rousette bat (ERB), which sheds virus in saliva, urine, and feces. Frugivorous ERBs discard test-bitten and partially eaten fruit, potentially leaving infectious virus behind that could be consumed by other susceptible animals or humans. Historically, 8 of 17 known Marburg virus disease outbreaks have been linked to human encroachment on ERB habitats, but no linkag...
Source: Emerging Infectious Diseases - October 25, 2023 Category: Infectious Diseases Authors: Brian R Amman Amy J Schuh Gloria Akurut Kilama Kamugisha Dianah Namanya Tara K Sealy James C Graziano Eric Enyel Emily A Wright Stephen Balinandi Julius J Lutwama Rebekah C Kading Patrick Atimnedi Jonathan S Towner Source Type: research

LAMPPrimerBank, a manually curated database of experimentally validated loop-mediated isothermal amplification primers for detection of respiratory pathogens
ConclusionLAMPPrimerBank, as a pioneering database in the rapidly expanding field of isothermal NAAT, endeavors to confront the two challenges of the LAMP: primer design and discrimination of false-positive results. (Source: Infection)
Source: Infection - October 12, 2023 Category: Infectious Diseases Source Type: research

Factors associated with return-to-work outcomes in inpatient rehabilitation – a systematic scoping review
. (Source: Psychology, Health and Medicine)
Source: Psychology, Health and Medicine - October 12, 2023 Category: International Medicine & Public Health Authors: K. F öhnerH. SeippA. BeckerC. Maulbecker-ArmstrongA. SchneiderU. SeifartV. van der Wardta Department of General Practice, University of Marburg, Germanyb Faculty of Health Sciences, University of Applied Sciences Giessen, Germanyc Rehabilitation Clinic S Source Type: research

LAMPPrimerBank, a manually curated database of experimentally validated loop-mediated isothermal amplification primers for detection of respiratory pathogens
ConclusionLAMPPrimerBank, as a pioneering database in the rapidly expanding field of isothermal NAAT, endeavors to confront the two challenges of the LAMP: primer design and discrimination of false-positive results. (Source: Infection)
Source: Infection - October 12, 2023 Category: Infectious Diseases Source Type: research

Marburg virus: Africa's deadly intruder exposed
Ann Med Surg (Lond). 2023 Sep 4;85(10):5297-5298. doi: 10.1097/MS9.0000000000001227. eCollection 2023 Oct.NO ABSTRACTPMID:37811117 | PMC:PMC10553113 | DOI:10.1097/MS9.0000000000001227 (Source: Annals of Medicine)
Source: Annals of Medicine - October 9, 2023 Category: Internal Medicine Authors: Maryam Shahzad Sean K Shaeen Abdullah Malikzai Source Type: research

Quality of breaking bad news to patients diagnosed with neoplasia of the uterine cervix
ConclusionThe process of breaking bad news in German women diagnosed with cervical neoplasia requires substantial improvement. The SPIKES protocol can be used as a guideline for enhancement but should be supplemented by incorporating a second consultation as the norm rather than the exception. Continuous monitoring and improvement of the quality of BBN is recommended for all oncologic institutions, utilizing the MABBAN questionnaire as a valuable tool. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - October 4, 2023 Category: Cancer & Oncology Source Type: research