WSV2023 - The second meeting of the world society for virology: One health - One world - One virology
Discussions further explored SARS-CoV-2 RNA replicons as vaccine candidates, SARS-CoV-2 in humans and animals, and the significance of plant viruses in the 'One Health' paradigm. The presence of the presidents from three virology societies, namely the American, Indian, and Korean Societies for Virology, highlighted the event's significance. Additionally, past president of the American Society for Virology (ASV), formally declared the partnership between ASV and WSV during the conference.PMID:38527382 | DOI:10.1016/j.virol.2024.110049 (Source: Virology)
Source: Virology - March 25, 2024 Category: Virology Authors: Ahmed S Abdel-Moneim Modra Murovska Maria S öderlund-Venermo Vikram N Vakharia William C Wilson Douglas P Gladue Matthew D Moore Covadonga Alonso Sayed F Abdelwahab Marietjie Venter Yashpal S Malik Shi Zhengli Shailendra K Saxena Anupam Varma Richard J K Source Type: research
WSV2023 - The second meeting of the world society for virology: One health - One world - One virology
Discussions further explored SARS-CoV-2 RNA replicons as vaccine candidates, SARS-CoV-2 in humans and animals, and the significance of plant viruses in the 'One Health' paradigm. The presence of the presidents from three virology societies, namely the American, Indian, and Korean Societies for Virology, highlighted the event's significance. Additionally, past president of the American Society for Virology (ASV), formally declared the partnership between ASV and WSV during the conference.PMID:38527382 | DOI:10.1016/j.virol.2024.110049 (Source: Virology)
Source: Virology - March 25, 2024 Category: Virology Authors: Ahmed S Abdel-Moneim Modra Murovska Maria S öderlund-Venermo Vikram N Vakharia William C Wilson Douglas P Gladue Matthew D Moore Covadonga Alonso Sayed F Abdelwahab Marietjie Venter Yashpal S Malik Shi Zhengli Shailendra K Saxena Anupam Varma Richard J K Source Type: research
Diagnosis and treatment of venous thromboembolism during pregnancy relate to genetic polymorphism
CONCLUSION: Inherited thrombophilia significantly associated with the development of VTE, especially the FVL and PGM, however the relation between MTHFR gene mutation and pregnancy-related VTE remains controversial, further study is needed. In addition, the dosages of heparin in the treatment of VTE during pregnancy suggested to adjusted based on gene polymorphism in FVL and PGM, and establish better prediction models is a direction of future research.PMID:38490955 | DOI:10.1177/17085381241240554 (Source: Vascular)
Source: Vascular - March 15, 2024 Category: Surgery Authors: Qingcheng Yang Xuechang Wang Rui Wang Aihua Li Source Type: research
Diagnosis and treatment of venous thromboembolism during pregnancy relate to genetic polymorphism
CONCLUSION: Inherited thrombophilia significantly associated with the development of VTE, especially the FVL and PGM, however the relation between MTHFR gene mutation and pregnancy-related VTE remains controversial, further study is needed. In addition, the dosages of heparin in the treatment of VTE during pregnancy suggested to adjusted based on gene polymorphism in FVL and PGM, and establish better prediction models is a direction of future research.PMID:38490955 | DOI:10.1177/17085381241240554 (Source: Vascular)
Source: Vascular - March 15, 2024 Category: Surgery Authors: Qingcheng Yang Xuechang Wang Rui Wang Aihua Li Source Type: research
Diagnosis and treatment of venous thromboembolism during pregnancy relate to genetic polymorphism
CONCLUSION: Inherited thrombophilia significantly associated with the development of VTE, especially the FVL and PGM, however the relation between MTHFR gene mutation and pregnancy-related VTE remains controversial, further study is needed. In addition, the dosages of heparin in the treatment of VTE during pregnancy suggested to adjusted based on gene polymorphism in FVL and PGM, and establish better prediction models is a direction of future research.PMID:38490955 | DOI:10.1177/17085381241240554 (Source: Vascular)
Source: Vascular - March 15, 2024 Category: Surgery Authors: Qingcheng Yang Xuechang Wang Rui Wang Aihua Li Source Type: research
Functional connectivity alterations in individuals with gaming disorder assessed by functional magnetic resonance imaging: a systematic review
. (Source: Journal of Addictive Diseases)
Source: Journal of Addictive Diseases - March 12, 2024 Category: Addiction Authors: Apolinario de Oliveira BotelhoFrancieli Bernardo RibeiroJ éssica Soares MachadoDaiane Cristini Barbosa de Souzaa Federal Institute of Education, Science and Technology of Santa Catarina, Brazilb University Hospital of Gießen and Marburg, Germany Source Type: research
Spontaneous hypoglycemia: should we mind the gap? Long-term follow-up of healthy people who met Whipple's triad criteria
CONCLUSION: The high percentage of patients who are discharged as "healthy" and still have symptoms after many years is disturbing. It is possible that the symptoms are not due to low blood glucose. We urge caution with use of the term "healthy". We advocate a multidisciplinary therapeutic approach after an organic cause of hypoglycemia has been ruled out. Psychosomatic treatment seems to be useful. In addition, more research should be conducted on this topic.PMID:38457064 | DOI:10.1007/s42000-024-00542-1 (Source: Hormones)
Source: Hormones - March 8, 2024 Category: Endocrinology Authors: Jan Adelmeyer Christian Marcel Schauer Peter Herbert Kann Source Type: research
The Current Pathogenicity and Potential Risk Evaluation of Marburg Virus to Cause Mysterious "Disease X"-An Update on Recent Evidences
Environ Health Insights. 2024 Mar 4;18:11786302241235809. doi: 10.1177/11786302241235809. eCollection 2024.ABSTRACTThe World Health Organization (WHO) defined Disease X as an upcoming disease with the potential to cause a pandemic. Pathogen X is responsible for Disease X. Marburg virus disease (MVD) is one of the diseases from the priority disease list published by WHO. Marburg virus is a filamentous, negative-sense RNA virus that belongs to the same filovirus family as the lethal Ebola virus. Since the first discovery of this virus in 1967, 17 outbreaks occurred sporadically till 2023. Rousettus aegyptiacus acts as the na...
Source: Environmental Health Insights - March 5, 2024 Category: Environmental Health Authors: Rahima Akter Mitu Md Rabiul Islam Source Type: research
The Current Pathogenicity and Potential Risk Evaluation of Marburg Virus to Cause Mysterious "Disease X"-An Update on Recent Evidences
Environ Health Insights. 2024 Mar 4;18:11786302241235809. doi: 10.1177/11786302241235809. eCollection 2024.ABSTRACTThe World Health Organization (WHO) defined Disease X as an upcoming disease with the potential to cause a pandemic. Pathogen X is responsible for Disease X. Marburg virus disease (MVD) is one of the diseases from the priority disease list published by WHO. Marburg virus is a filamentous, negative-sense RNA virus that belongs to the same filovirus family as the lethal Ebola virus. Since the first discovery of this virus in 1967, 17 outbreaks occurred sporadically till 2023. Rousettus aegyptiacus acts as the na...
Source: Environmental Health Insights - March 5, 2024 Category: Environmental Health Authors: Rahima Akter Mitu Md Rabiul Islam Source Type: research
Transcriptomics of Marburg virus-infected primary proximal tubular cells reveals negative correlation of immune response and energy metabolism
In conclusion, Marburg virus infects and replicates in human primary PTC and induces downregulation of processes known to be relevant for acute kidney injury as well as a strong inflammatory response.PMID:38346476 | DOI:10.1016/j.virusres.2024.199337 (Source: Virus Research)
Source: Virus Research - February 12, 2024 Category: Virology Authors: Benjamin Koch Maximilian Filzmayer Sammy Patyna Nils Wetzstein Sebastian Lampe Tobias Schmid Helmut Geiger Patrick C Baer Olga Dolnik Source Type: research
Recent Advancements in the Therapeutic Development for Marburg Virus: Updates on Clinical Trials
AbstractPurpose of ReviewWe aim to provide valuable insights into the current state of therapeutic development for the deadly Marburg virus and guide researchers and clinicians to study the emerging therapies and shape future directions against this deadly virus.Recent FindingsWe find considerable progress in understanding the molecular biology and pathogenesis of the Marburg virus, leading to the identification of small-molecule antivirals and host-targeted approaches, including RNA polymerase inhibitors, viral entry inhibitors, and RNA interference therapies. However, there are very few ongoing clinical trials on the the...
Source: Current Infectious Disease Reports - February 1, 2024 Category: Infectious Diseases Source Type: research
Prophylactic and therapeutic measures for emerging and re-emerging viruses: artificial intelligence and machine learning - the key to a promising future
ConclusionsThe present review not only highlighted public-health management models but also provide leads in potential therapeutic targets as well as vaccine/ antiviral candidates. To support the context, the issues with existing therapeutic strategies are also overviewed and the prospects were identified. This review discusses a wide range of applications of AI and ML pertaining to the clinical domain. (Source: Health and Technology)
Source: Health and Technology - January 24, 2024 Category: Information Technology Source Type: research
