Guinea: Health Authorities Declare End of Marburg Virus Disease Outbreak
[WHO-AFRO] Brazzaville/Conakry -- Guinea today declared the end of the Marburg virus disease outbreak having recorded no new cases over the past 42 days--two incubation periods, or the time between infection and the onset of symptoms. The virus was confirmed on 9 August, marking the first time the disease emerged in the country and in West Africa. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 17, 2021 Category: African Health Source Type: news

Guinea: Marburg in Guinea - the Value of Lessons From Managing Other Haemorrhagic Outbreaks
[The Conversation Africa] As the COVID-19 pandemic rages on in Africa amid insufficient vaccination rollout, viral haemorrhagic fever has again raised its head. This adds to public health turmoil on the continent where resources to respond to emerging and re-emerging epidemic prone zoonotic diseases remain limited. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 12, 2021 Category: African Health Source Type: news

West Africa: The First Human Case of Marburg Virus in West Africa Is No Surprise - Here's Why
[The Conversation Africa] The first case of fatal Marburg virus disease was identified in Guinea, West Africa on 9 August 2021. Marburg is a highly infectious zoonotic haemorrhagic fever transmitted to people from fruit bats, specifically the Egyptian Rousette bat (Rousettus aegyptiacus). It spreads among humans through direct contact with the bodily fluids of infected people, surfaces and materials. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 31, 2021 Category: African Health Source Type: news

Why The Discovery Of Marburg Virus In West Africa Is A Concern
When zoonotic diseases spillover from wildlife into people it can be very difficult to tell whether what we observe is a singular event, one off and unlikely to lead to anything, or the tip of an iceberg. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 25, 2021 Category: Pharmaceuticals Authors: John Drake, Contributor Tags: Science /science Innovation /innovation Healthcare /healthcare Source Type: news

West Africa: Covid-19 Deaths Surge in West Africa Amid Ebola and Other Outbreaks - WHO
[WHO-AFRO] Brazzaville -- West Africa has recorded its highest number of COVID-19 deaths since the pandemic began as several countries grapple with outbreaks of cholera, Ebola Virus Disease and Marburg Virus Disease that threaten to further strain the already stretched emergency response capacity in the region. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 20, 2021 Category: African Health Source Type: news

Death Reported From Ebola-Like Marburg Virus in West Africa Death Reported From Ebola-Like Marburg Virus in West Africa
A deadly case of the Marburg virus has been identified in Guinea, the first time in the West Africa region.WebMD Health News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 13, 2021 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Death Reported From Ebola-Like Marburg Virus in West Africa
A deadly case of the Marburg virus has been identified in Guinea, the first-time in the West Africa region. (Source: WebMD Health)
Source: WebMD Health - August 13, 2021 Category: Consumer Health News Source Type: news

Marburg virus warning: Why the UK MUST be 'vigilant' for deadly Ebola-like virus symptoms
MARBURG virus was spotted in West Africa earlier this week, the World Health Organization confirmed, when a patient tested positive and subsequently died of the Ebola-like disease. A doctor has now warned people in the UK to remain "vigilant" for any signs or symptoms of the Marburg virus. (Source: Daily Express - Health)
Source: Daily Express - Health - August 13, 2021 Category: Consumer Health News Source Type: news

WHO supports Guinea after detection of first-ever case of Marburg disease
The World Health Organization (WHO) is supporting Guinea following a confirmed death from Marburg virus disease, the first known case in the country and West Africa, the UN agency reported on Wednesday.  (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - August 11, 2021 Category: International Medicine & Public Health Source Type: news

Liberia: Marburg Hemorrhagic Fever Discovered in Neighboring Guinea
[FrontPageAfrica] Monrovia -- The World Health Organization (WHO)-Liberia Country Office has notified the National Public Health Institute of Liberia (NPHIL) of two confirmed cases of Marburg Hemorrhagic Fever in Gueckedou, the Republic of Guinea. The patients are 46-year-old male and a female (age unknown) who were both residents of Temessadou, a Sub-Prefecture of Gueckedou. The Guinean Health Authorities were alerted by community members of Koundou Lengo Bengou which is 54 kilometers away from Gueckedou. This is the first time Marbur (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 11, 2021 Category: African Health Source Type: news

Deadly Ebola-like Marburg virus could ‘spread far and wide’ if not stopped: WHO
A man who died in West Africa has tested positive for the Ebola-like Marburg virus — with health officials scrambling to stop the killer... (Source: Reuters: Health)
Source: Reuters: Health - August 10, 2021 Category: Consumer Health News Source Type: news

Guinea confirms first case of deadly Marburg virus months after end of Ebola outbreak
Part of the same virus family as Ebola, Marburg has a fatality rate that can reach up to 90%, as the person who had it has died. (Source: Reuters: Health)
Source: Reuters: Health - August 10, 2021 Category: Consumer Health News Source Type: news

Marburg Virus Disease Detected in West Africa for First Time
The finding of the Ebola-like disease, which killed a man in Guinea, has prompted public health measures. (Source: The Scientist)
Source: The Scientist - August 10, 2021 Category: Science Tags: News & Opinion Source Type: news

WHO, Guinea find at least 4 contacts of Marburg virus victim
The World Health Organization says at least four people have turned up as contacts of a man who died in Guinea from the Ebola-like Marburg virus (Source: ABC News: Health)
Source: ABC News: Health - August 10, 2021 Category: Consumer Health News Tags: Health Source Type: news

Marburg virus symptoms: Highly infectious virus has potential to spread 'far and wide'
THE WORLD Health Organization have confirmed the first Marburg virus death in West Africa. What is the highly contagious Marburg virus, and what are the symptoms of the illness? (Source: Daily Express - Health)
Source: Daily Express - Health - August 10, 2021 Category: Consumer Health News Source Type: news

West Africa: First-Ever Case of Marburg Virus Disease Confirmed in Guinea
[WHO-AFRO] Brazzaville/Conakry -- Health authorities in Guinea today confirmed a case of Marburg virus disease in the southern Gueckedou prefecture. This is the first time Marburg, a highly infectious disease that causes haemorrhagic fever, has been identified in the country, and in West Africa. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 10, 2021 Category: African Health Source Type: news

Guinea reports West Africa's first known Marburg virus death
Authorities in West Africa have confirmed the region’s first known case of Marburg virus after at least one person in Guinea died of the hemorrhagic fever disease (Source: ABC News: Health)
Source: ABC News: Health - August 9, 2021 Category: Consumer Health News Tags: Health Source Type: news

Probable Case Of Ebola-Like Marburg Virus In Guinea
Marburg virus may have been identified for the first time in West Africa. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 7, 2021 Category: Pharmaceuticals Authors: Judy Stone, Senior Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news

Probable Case Of Ebola-Like Marburg Virus Identified In Guinea
Marburg virus may have been identified for the first time in West Africa. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 7, 2021 Category: Pharmaceuticals Authors: Judy Stone, Senior Contributor Tags: Healthcare /healthcare Innovation /innovation Editors' Pick editors-pick Source Type: news

Anti-tumor agent from the intestine
(University of W ü rzburg) Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from german universities in W ü rzburg and Marburg reveals. The findings could help improve cancer therapies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 9, 2021 Category: International Medicine & Public Health Source Type: news

Blocking viruses' exit strategy
(University of Pennsylvania) The Marburg virus, a relative of Ebola, likewise causes a dangerous and often fatal disease. In a study co-led by the University of Pennsylvania's Ronald Harty, an experimental antiviral drug, which prevents the virus from exiting host cells and spreading to new cells, showed promising results. The researchers are also encouraged by similarities in the drug's response against SARS-CoV-2, the virus that causes COVID-19. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 6, 2021 Category: Biology Source Type: news

Exclusive: Inside the Facilities Making the World ’s Most Prevalent COVID-19 Vaccine
If you’ve been vaccinated for COVID-19, chances are pretty high that you’re benefiting from a product made by BioNTech. The German biotech company, co-founded by a husband-and-wife team of scientists, developed the vaccine that became not only the first to earn authorization in the U.S. for COVID-19 in December but also the first ever based on a new technology involving the genetic material mRNA. In interviews in December and March, co-founders Ugur Sahin and Ozlem Tureci spoke about their whirlwind year and their partnership with U.S. pharmaceutical company Pfizer to test and manufacture the vaccine. Over thre...
Source: TIME: Health - April 19, 2021 Category: Consumer Health News Authors: Alice Park and Aryn Baker/Marburg, Germany Tags: Uncategorized COVID-19 Exclusive feature longform Magazine photography Source Type: news

‘Where the magic happens’ — inside BioNTech’s innovative vaccine plant
Marburg facility in Germany is first to make approved coronavirus vaccine using mRNA technology (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - April 2, 2021 Category: Pharmaceuticals Source Type: news

BioNTech-Pfizer raise 2021 vaccine output goal to 2.5 billion doses
Pfizer previously said the partners would likely produce between 2.3 billion and 2.4 billion doses in 2021. BioNTech cited its new facility in the German city of Marburg and an expansion of the pair's network of third-party manufacturers and suppliers as drivers of the larger volumes. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 30, 2021 Category: Pharmaceuticals Source Type: news

BioNTech provides update on vaccine production status at Marburg manufacturing site
BioNTech SE today announced that the European Medicines Agency (EMA) approved the manufacturing of the COVID-19 vaccine drug product at the facility in Marburg. As part of the process, EMA has approved the production of the drug substance, the mRNA, at the Marburg site over the course of this week. (Source: World Pharma News)
Source: World Pharma News - March 26, 2021 Category: Pharmaceuticals Tags: Featured Business Business and Industry Source Type: news

Combination therapy protects against advanced Marburg virus disease
(University of Texas Medical Branch at Galveston) A new study conducted at the Galveston National Laboratory at the The University of Texas Medical Branch at Galveston (UTMB) has shown substantial benefit to combining monoclonal antibodies and the antiviral remdesivir against advanced Marburg virus. The study was published today in Nature Communications. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 25, 2021 Category: Infectious Diseases Source Type: news

The medieval German town at the heart of the fight against Covid
BioNTech’s vaccine facility in Marburg will produce 750m doses a year (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - February 22, 2021 Category: Pharmaceuticals Source Type: news

New study suggests better approach in search for COVID-19 drugs
(University of Kent) Research from the University of Kent, Goethe-University in Frankfurt am Main, and the Philipps-University in Marburg has provided crucial insights into the biological composition of SARS-CoV-2, the cause of COVID-19, revealing vital clues for the discovery of antiviral drugs. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 11, 2021 Category: Infectious Diseases Source Type: news

New drug target for Ebola, Marburg viruses
(University of Illinois at Chicago) Researchers have identified a previously unknown site on the filovirus glycoprotein to which small drug molecules can bind and prevent infection -- blocking both sites may be a more effective treatment while reducing the risk of side effects. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 8, 2021 Category: Infectious Diseases Source Type: news

SARS-CoV-2-Neutralizing-Antibody-enters-Clinical-Phase
New SARS-CoV-2 Neutralizing Antibody enters Clinical PhaseCologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim collaborate on potential COVID-19 therapy and preventionBI 767551 (DZIF-10c) is a potent anti-SARS-CoV-2 antibody that has shown promising virus neutralizing properties in pre-clinical researchPhase 1/2a clinical trials will evaluate the safety, pharmacokinetics, and antiviral activity of BI 767551 administered by intravenous infusion and by inhalation. The first patients have already been enrolled. (Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - December 18, 2020 Category: Research Source Type: news

New SARS-CoV-2 neutralizing antibody enters clinical phase
(German Center for Infection Research) Cologne University Hospital, University of Marburg, the German Center for Infection Research and Boehringer Ingelheim collaborate on potential COVID-19 therapy and prevention (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 18, 2020 Category: Infectious Diseases Source Type: news

Water at the end of the tunnel
(Max Planck Institute for Marine Microbiology) We humans need oxygen to breath - for a lot of microbes it is a lethal poison. That is why microorganisms have developed ways to render oxygen molecules harmless. Microbiologists from Bremen, Marburg and Grenoble have now succeeded in decrypting such a mechanism. They show, how methane-generating microbes transform oxygen into water without causing any damage to the cell. These findings are relevant for future bio-inspired processes. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 28, 2020 Category: Biology Source Type: news

Researcher gets $2.94 million federal grant to study unique features of Ebola and marburg viruses
(Georgia State University) Dr. Christopher Basler, professor and director of the Center for Microbial Pathogenesis in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.94 million federal grant to study unique features of Ebola and Marburg viruses that control how the virus family expresses its genes and escapes immune responses. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 15, 2020 Category: Infectious Diseases Source Type: news

New substance library to accelerate the search for active compounds
(Helmholtz-Zentrum Berlin f ü r Materialien und Energie) The MX team at HZB and a Group at the University of Marburg have established a new substance library. It consists of 1103 organic molecules that could be used as building blocks for new drugs. Now, this library has been validated at MAX IV. The substance library of the HZB is available for research worldwide and also plays a role in the search for active substances against SARS-CoV-19. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2020 Category: International Medicine & Public Health Source Type: news

Cancer drug cures COVID-19 patient with acute respiratory distress
(Philipps-Universit ä t Marburg) A successfully treated case at the Marburg University Medical Center is raising hope for a COVID-19 cure: The team has successfully used the cancer drug ruxolitinib for the first time to cure a patient suffering from acute respiratory distress syndrome (ARDS) after infection with the coronavirus SARS-CoV-2. Oncologist Professor Dr. Andreas Neubauer and his colleagues report on the successfully treated case in the scientific journal Leukemia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 18, 2020 Category: Cancer & Oncology Source Type: news

US inroads to better Ebola vaccine
(Flinders University) As the world focuses on finding a COVID-19 vaccine, research continues on other potentially catastrophic pandemic diseases, including Ebola and Marburg viruses. In the latest collaboration with US partners, a vaccine turbocharger called Advax ™ adjuvant, was combined with a synthetic protein against Ebola developed by the United States Army Medical Research Institute of Infectious Disease (USAMRIID). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 18, 2020 Category: International Medicine & Public Health Source Type: news

Researchers uncover mechanisms of protective antibody response during Marburg infection
(University of Texas Medical Branch at Galveston) A detailed study of the monoclonal antibodies from a person who survived a Marburg infection led researchers to identify novel mechanisms that contribute protection against the disease, according to the latest findings of a collaborative team led by The University of Texas Medical Branch at Galveston and Vanderbilt University Medical Center. The findings are now available in Cell Host& Microbe. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 21, 2020 Category: International Medicine & Public Health Source Type: news

Researchers show how Ebola virus hijacks host lipids
(Biophysical Society) Robert Stahelin studies some of the world's deadliest viruses. Filoviruses, including Ebola virus and Marburg virus, cause viral hemorrhagic fever with high fatality rates. Stahelin, professor at Purdue University, examines how these viruses take advantage of human host cells. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 15, 2020 Category: Infectious Diseases Source Type: news

Coronavirus outbreak raises question: Why are bat viruses so deadly?
It's no coincidence that some of the worst viral disease outbreaks in recent years - SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus - originated in bats. A new University of California, Berkeley, study finds that bats' fierce immune response to viruses could drive viruses to replicate faster, so that when they jump to mammals with average immune systems, such as humans, the viruses wreak deadly havoc. (Source: World Pharma News)
Source: World Pharma News - February 10, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Rapid Response Toolbox
Source: Medical Mission Institute. Published: 2/2020. This toolbox, updated in February 2020, provides information and materials about rapid response to diseases and outbreaks, including situation reports about COVID-19 (coronavirus disease), plague, cholera, Marburg Virus, and Yellow Fever. It provide clinical guidelines, including for COVID-19,chikungunya, dengue, Ebola, and Zika; information about communication and training; and prevention and control information. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 1, 2020 Category: International Medicine & Public Health Source Type: news

How Do Bats Live With So Many Viruses?
They are considered the probable source of the coronavirus outbreak spreading from China. It turns out that they may have an immune system that lets them coexist with many disease-causing viruses. (Source: NYT Health)
Source: NYT Health - January 29, 2020 Category: Consumer Health News Authors: James Gorman Tags: Bats Viruses Epidemics Coronavirus (2019-nCoV) Marburg Virus Nipah Virus Hendra Virus SARS (Severe Acute Respiratory Syndrome) MERS (Middle East Respiratory Syndrome) Immune System Cell Host and Microbe (Journal) EcoHealth Alliance Source Type: news

Marburg virus found in Sierra Leone bats
(University of California - Davis) Scientists have detected Marburg virus in fruit bats in Sierra Leone, marking the first time the deadly virus has been found in West Africa. Eleven Egyptian rousette fruit bats tested positive for active Marburg virus infection. The presence of Marburg virus, a close relative to Ebola virus that also causes hemorrhagic disease in people, was detected in advance of any reported cases of human illness in Sierra Leone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 24, 2020 Category: Infectious Diseases Source Type: news

Ebola and Marburg Fevers: Annual Epidemiological Report for 2018; Surveillance Report
Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 12/2019. This three-page report on cases of Ebola and Marburg fevers is based on data for 2018 retrieved from The European Surveillance System (TESSy) on September 10, 2019. For 2018, no cases of Ebola virus disease and Marburg hemorrhagic fever were reported in the European Union/European Economic Area. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 1, 2019 Category: International Medicine & Public Health Source Type: news

Integral Molecular to advance vaccine discovery with NIH contract for $5.5 million
(Integral Molecular) The NIH has awarded Integral Molecular a contract which will provide up to $5.5M over the next five years to define antibody responses to pathogenic viruses including Zika, Marburg and equine encephalitis viruses (EEV), aiding the discovery of vaccines and therapeutics against these currently untreatable and often lethal viruses. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 14, 2019 Category: Infectious Diseases Source Type: news

Study vaccine protects monkeys against four types of hemorrhagic fever viruses
The vaccine provided protection from Ebola virus, Sudan virus, Marburg virus and Lassa virus. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - November 8, 2019 Category: American Health Source Type: news

Health Emergency Preparedness for Imported Cases of High-Consequence Infectious Diseases: Operational Checklist for Country Preparedness Planning in the EU/EEA Countries; Technical Report
Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 10/22/2019. To support countries in the European Union/European Economic Area (EU/EEA) in their review of preparedness system planning, this 21-page document provides an operational checklist for health emergency preparedness for imported cases of high-consequence infectious diseases. These diseases include Ebola virus disease, Crimean Congo hemorrhagic fever, Marburg virus disease, highly pathogenic avian influenza, pneumonic plague, and severe acute respiratory syndrome. The checklist describes the system elements that need to ...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - October 22, 2019 Category: International Medicine & Public Health Source Type: news

Ebola in Zaire, 1976: The Past as Prologue
Source: Centers for Disease Control and Prevention (CDC). Published: 9/5/2019. This one-hour, 29-minute lecture, part of the Centers for Disease Control and Prevention (CDC) Office of Science “We Were There” series, details how disease detectives discovered the Ebola virus in 1976 in Zaire (now the Democratic Republic of the Congo), and how the understanding of it has grown with subsequent outbreaks over the past 40 years. Samples of the unidentified disease in that outbreak yielded alarming images of a filovirus resembling Marburg, but serology testing at the CDC showed a new virus, later named Ebola. (Video...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - September 5, 2019 Category: International Medicine & Public Health Source Type: news

GSK ends development of Ebola vaccine, hands work to U.S. institute
British drugmaker GlaxoSmithKline is giving up its work on developing three potential vaccines against the deadly Ebola and Marburg viruses, despite an ongoing Ebola outbreak in Democratic Republic of Congo. (Source: Reuters: Health)
Source: Reuters: Health - August 6, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

A Nationwide Flash-Mob Study for Suspected ACS A Nationwide Flash-Mob Study for Suspected ACS
The authors used a"flash mob" methodology to determine whether acute coronary syndrome can be safely ruled out using the Marburg Heart Score or FP clinical assessment in an emergency care setting.Annals of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 25, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

'Flash mob' study puts clinical decision rules for ACS to the test
(American Academy of Family Physicians) A novel 'flash mob' study finds that, in emergency care, acute coronary syndrome cannot be safely ruled out using the Marburg Heart Score or the family physicians' clinical assessment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 10, 2019 Category: International Medicine & Public Health Source Type: news