UTMB to lead program to advance treatments against potentially bioterrorist pathogens
(University of Texas Medical Branch at Galveston) The University of Texas Medical Branch at Galveston, Profectus Biosciences, Vanderbilt University Medical Center, Mapp Biopharmaceutical and Genevant Sciences Corp. have been awarded up to $35 million to advance the development of rapid-acting vaccines and broad-spectrum treatments of the highly lethal hemorrhagic fever viruses Ebola and Marburg. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 8, 2019 Category: International Medicine & Public Health Source Type: news

Pan-filovirus T-cell vaccine protects mice from Ebola and Marburg
(PLOS) Vaccines that induce protective T-cell responses could protect against members across the filovirus family, according to a study published Feb. 28 in the open-access journal PLOS Pathogens by Tom á š Hanke of the University of Oxford, Bette Korber of the Los Alamos National Laboratory, and colleagues (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 28, 2019 Category: Infectious Diseases Source Type: news

Strangers in the Land: A Congolese Murder Case
A man walks down the street. It's a street in a strange world. Maybe it's the Third World. Maybe it's his first time around. He doesn't speak the language. He holds no currency. He is a foreign man. He is surrounded by the sound. The sound! Cattle in the marketplace, scatterlings and orphanages. He looks around, around.By Jan LundiusSTOCKHOLM / ROME, Jan 21 2019 (IPS)I thought about this song by Paul Simon while I in 2011 spent a few weeks in Kinshasa. I was a foreign man in a strange world, surrounded by sights and sounds, completely dependent on my new-found Congolese friends. When our taxi got stuck in a traffic jam and...
Source: IPS Inter Press Service - Health - January 21, 2019 Category: International Medicine & Public Health Authors: Jan Lundius Tags: Africa Aid Armed Conflicts Crime & Justice Featured Headlines Health Human Rights TerraViva United Nations Source Type: news

Ebola and Marburg Haemorrhagic Fevers: Outbreaks and Case Locations
Source: United Kingdom Department of Health (DH). Published: 1/10/2019. This Web page, updated in January 2019, provides information about incidents and outbreaks of Ebola and Marburg, both viral hemorrhagic fevers (VHF). It describes current incidents and outbreaks, including the outbreak of Ebola virus disease in North-Kivu Province, Democratic Republic of Congo (DRC); outbreaks in 2017; the West Africa outbreak 2014 to 2016; linked Ebola outbreaks and cases in other countries (2014 to 2015); and a historic map of outbreaks. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - January 10, 2019 Category: International Medicine & Public Health Source Type: news

Newly Identified Virus Similar to Ebola, Marburg
Mengla virus, detected in bats in China, infects cells through the same host receptor targeted by the deadly pathogens. (Source: The Scientist)
Source: The Scientist - January 9, 2019 Category: Science Tags: News & Opinion Source Type: news

New bat-borne virus related to Ebola discovered by Singapore team
(Duke University Medical Center) Newly discovered Mengla virus is evolutionarily closely related to Ebola virus and Marburg virus and shares several important functional similarities with them. For example, the genome organisation of the Mengl à virus is consistent with other filoviruses, coding for seven genes. The Mengl à virus also uses the same molecular receptor, a protein called NPC1, as Ebola virus and Marburg virus to gain entry into cells and cause infection. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 7, 2019 Category: International Medicine & Public Health Source Type: news

Bats in Sierra Leone Carry Marburg Virus
It's the first time the deadly pathogen has been found in West Africa. (Source: The Scientist)
Source: The Scientist - December 31, 2018 Category: Science Tags: News & Opinion Source Type: news

Global Health: Marburg Virus, Related to Ebola, Is Found in Bats in West Africa
The discovery was part of a U.S.-led effort to spot dangerous pathogens in animals before humans are endangered. (Source: NYT Health)
Source: NYT Health - December 24, 2018 Category: Consumer Health News Authors: DONALD G. McNEIL Jr. Tags: Marburg Virus Bats Epidemics Centers for Disease Control and Prevention United States Agency for International Development University of California, Davis Africa Source Type: news

Sierra Leone: Deadly Marburg Virus Found in Bats in Sierra Leone
[East African] Scientists in Sierra Leone have found fruit-eating bats infected with the deadly Marburg virus, the health ministry said Thursday. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 24, 2018 Category: African Health Source Type: news

Sierra Leone Fruit Bats Infected With Ebola-like Marburg Virus Sierra Leone Fruit Bats Infected With Ebola-like Marburg Virus
Scientists in Sierra Leone have found live bats infected with Marburg virus, a deadly hemorrhagic fever similar to Ebola and so far undetected in West Africa, a U.S. government statement said on Thursday.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 21, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Sierra Leone fruit bats infected with Ebola-like Marburg virus
Scientists in Sierra Leone have found live bats infected with Marburg virus, a deadly hemorrhagic fever similar to Ebola and so far undetected in West Africa, a U.S. government statement said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - December 20, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Deadly Marburg virus found in bats in Sierra Leone
The discovery marks the first time the pathogen — a cousin of Ebola — has been found in West Africa, raising the potential for it to cause outbreaks in humans in a new region. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - December 20, 2018 Category: Consumer Health News Authors: Lena H. Sun Source Type: news

New Field Test Discerns Between Ebola and Lookalike Fevers
At the close of the 2014-2016 West Africa Ebola crisis, the Paul G. Allen Foundation identified diagnostic gaps as one of the major deficiencies that had contributed to the outbreak’s spread. “The standard diagnostic tests that exist are very good, but they’re hard to do out in the field in the middle of an outbreak like we saw in West Africa,” said John Connor, a virologist at the Boston University National Emerging Infectious Diseases Laboratory (NEIDL). Instead, samples need to be sent to a facility capable of running the tests, which means it could...
Source: MDDI - December 13, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news

Surveillance Report: Annual Epidemiological Report for 2016: Ebola and Marburg Fevers
Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 12/12/2018. This three-page report on Ebola and Marburg fevers is based on data for 2016 retrieved from The European Surveillance System (TESSy) on April 4, 2018. In 2016, no cases of Ebola viral hemorrhagic fever and Marburg hemorrhagic fever were reported in the European Union/European Economic Area, with 26 countries reporting case-based data. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 12, 2018 Category: International Medicine & Public Health Source Type: news

Scientists to test tailor-made vaccine tech to fight epidemics
A global coalition set up to fight disease epidemics is investing up to $8.4 million to develop a synthetic vaccine system that could be tailor-made to fight multiple pathogens such as flu, Ebola, Marburg and Rabies. (Source: Reuters: Health)
Source: Reuters: Health - December 10, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Compendium of Short Reports on Selected Outbreaks in the WHO (World Health Organization) African Region: 2016-2018
Source: World Health Organization, Regional Office for Africa. Published: 12/2018. This 96-page report is a collection of short reports on selected outbreaks that occurred in the World Health Organization (WHO) African Region between 2016 and 2018, and which were successfully controlled. This edition of the Compendium covers 19 outbreaks, which occurred in 15 countries, presented in chronological order. Outbreaks include Ebola virus disease in Democratic Republic of the Congo (Likati, May 2017), Marburg fever in Uganda, dengue fever in Senegal, Crimean-Congo hemorrhagic fever in Mauritania, influenza A H1N1 in Ghana, Lass...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 1, 2018 Category: International Medicine & Public Health Source Type: news

Walter Reed Army Institute of Research begins phase 1 clinical trial of Marburg vaccine
(Walter Reed Army Institute of Research) WRAIR this week administered the first vaccine in a Phase 1 clinical trial to evaluate the safety and immunogenicity of a Marburg vaccine candidate in healthy adult volunteers. The WRAIR study evaluates the VRC-MARADC087-00-VP vaccine, developed by the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). The Marburg virus is in the same family as Ebola and causes severe hemorrhagic fever in humans. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 15, 2018 Category: Infectious Diseases Source Type: news

Mechanism of Marburg virus sexual transmission identified in nonhuman primates
(US Army Medical Research Institute of Infectious Diseases) Research by Army scientists elucidates the mechanism of sexual transmission of filoviruses, which have been shown to persist in the testes and other immune privileged sites. Sexual transmission of filoviruses was first reported in 1968 after an outbreak of Marburg virus disease and recently caused flare-ups of Ebola virus disease in the 2013-2016 outbreak. The team found that Marburg virus persists in seminiferous tubules and that Sertoli cells are the reservoir for the virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 30, 2018 Category: Infectious Diseases Source Type: news

Boston University lab gets shipment of Ebola, Marburg viruses
Researchers at Boston University ’s infectious disease lab received the first pathogens it's gotten under its new heightened designation: the Ebola and Marburg viruses. The National Emerging Infectious Diseases Laboratories received clearance from the Boston Public Health Commission in December to be upgraded to a Biosafety Leve l 4 facility – the 10th in the country. The designation was years in the making, and came after intense scrutiny by state, city and federal officials, including approval… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - August 2, 2018 Category: Health Management Authors: Jessica Bartlett Source Type: news

Boston University lab gets shipment of Ebola, Marburg viruses
Researchers at Boston University ’s infectious disease lab received the first pathogens it's gotten under its new heightened designation: the Ebola and Marburg viruses. The National Emerging Infectious Diseases Laboratories received clearance from the Boston Public Health Commission in December to be upgraded to a Biosafety Leve l 4 facility – the 10th in the country. The designation was years in the making, and came after intense scrutiny by state, city and federal officials, including approval… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 2, 2018 Category: Biotechnology Authors: Jessica Bartlett Source Type: news

Bats may have co-opted viral proteins produced by Ebola for immune function
(Cell Press) Approximately 18 million years ago, genes encoding viral proteins 35 (VP35s) integrated into the genomes of Myotis (mouse-eared) bats. Produced by the highly deadly Ebola and Marburg viruses, VP35s suppress the host immune system and play a critical role in the efficient replication and virulence of these filoviruses. A study publishing July 24 in Cell Reports sheds light on the potential functional role of these so-called non-retroviral integrated RNA viral sequences (NIRVs) in bats. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 24, 2018 Category: Infectious Diseases Source Type: news

Study of bat natural immunity to Marburg virus may shed light on human disease
(US Army Medical Research Institute of Infectious Diseases) Scientists examining the genome of Egyptian fruit bats, a natural reservoir for the deadly Marburg virus, have identified several immune-related genes that suggest bats deal with viral infections in a substantially different way than primates. Their research, published online today in the journal Cell, demonstrates that bats may be able to host viruses that are pathogenic in humans by tolerating -- rather than overcoming -- the infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 26, 2018 Category: Infectious Diseases Source Type: news

Uganda:Team Keeps Finding New Virusus - Researcher
[Independent (Kampala)] Kampala -The government response to the 2017 Marburg virus outbreak in Kween District, eastern Uganda cost Shs5.2billion. Most of that money came from donors. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 11, 2018 Category: African Health Source Type: news

Uganda:Team Keeps Finding New Viruses - Researcher
[Independent (Kampala)] Kampala -The government response to the 2017 Marburg virus outbreak in Kween District, eastern Uganda cost Shs5.2billion. Most of that money came from donors. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 11, 2018 Category: African Health Source Type: news

Annual Epidemiological Report for 2015: Ebola and Marburg Fevers
European Union, European Centre for Disease Prevention and Control. 01/2018 This four-page surveillance report is based on data for 2015 retrieved from The European Surveillance System (TESSy) on December 12, 2016, and additional information from epidemic intelligence. It states that no cases of Ebola viral hemorrhagic fever and Marburg hemorrhagic fever infections were reported in European Union/European Economic Area (EU/EEA) countries in 2015. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 3, 2018 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

How bats carry viruses without getting sick
(Cell Press) Bats are known to harbor highly pathogenic viruses like Ebola or Marburg and yet they do not show clinical signs of disease. In a paper published in the journal Cell Host& Microbe on February 22, scientists at the Wuhan Institute of Virology in China find that in bats, an antiviral immune pathway called the STING-interferon pathway is dampened, and bats can maintain just enough defense against illness without triggering a heightened immune reaction. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 22, 2018 Category: Infectious Diseases Source Type: news

2018 Annual Review of the Blueprint List of Priority Diseases
World Health Organization. 02/08/2018 This Web page provides the 2018 List of Priority Diseases, which include Ebola virus disease and Marburg virus disease, Lassa fever, Middle East respiratory syndrome coronavirus (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS), and Zika virus. Experts consider that given their potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines, there is an urgent need for accelerated research and development for these diseases. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 11, 2018 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

TSRI scientists discover workings of first promising Marburg virus treatment
(Scripps Research Institute) Scientists at The Scripps Research Institute have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 10, 2018 Category: Infectious Diseases Source Type: news

Researchers inhibit ebola virus
(University of Copenhagen The Faculty of Health and Medical Sciences) The incurable Ebola virus has long been feared due to its high mortality rate and danger of infection. Now researchers from the University of Copenhagen and Phillips Universit ä t Marburg have succeeded in inhibiting the virus in cell cultures. The researchers hope to be able to continue doing animal testing and developing an actual drug. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 29, 2017 Category: Infectious Diseases Source Type: news

Uganda:MSF Ends Its Intervention in Response to the Marburg Fever Outbreak
[MSF] Ugandan authorities have declared the end of the Marburg fever outbreak that has affected the eastern part of the country since October. MSF provided support to local authorities, in particular in case management capacity and epidemic surveillance. MSF, the Ugandan Ministry of Health and their partners have also introduced new tools which will improve case management in future haemorrhagic fever outbreaks. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 11, 2017 Category: African Health Source Type: news

Uganda:Uganda Declared Marburg Free
[Monitor] Kampala -The Ministry of Health has declared Uganda Marburg free. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 9, 2017 Category: African Health Source Type: news

Uganda says it has contained an outbreak of Marburg hemorrhagic fever
KAMPALA (Reuters) - Uganda said on Friday it had successfully contained an outbreak of the Marburg virus, a highly infectious haemorrhagic fever announced by officials on Oct. 19, which killed three people. (Source: Reuters: Health)
Source: Reuters: Health - December 8, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Uganda controls deadly Marburg fever outbreak, WHO says
Uganda controls deadly Marburg fever outbreak, World Health Organization says (Source: ABC News: Health)
Source: ABC News: Health - December 8, 2017 Category: Consumer Health News Tags: Health Source Type: news

Uganda ends Marburg virus disease outbreak
Uganda has successfully controlled an outbreak of Marburg virus disease and prevented its spread only weeks after it was first detected, the World Health Organization said on Friday (December 8). “Uganda has led an exemplary response. Health authorities and partners, with the support of WHO, were able to detect and control the spread of Marburg virus disease within a matter of weeks,” said Dr Matshidiso Moeti, WHO Regional Director for Africa. (Source: WHO news)
Source: WHO news - December 8, 2017 Category: International Medicine & Public Health Tags: marburg [subject], marburg haemorrhagic fever Source Type: news

New outbreak: Deadly virus, similar to Ebola, with NO treatment... now strikes Uganda
(Natural News) Uganda is in the middle of a health care crisis as the deadly Marburg virus has once again hit the African nation. Health chiefs have announced that the virus, which is clinically similar to the Ebola virus, has been detected in five cases. The reports note that an emergency Marburg virus screening is being carried... (Source: NaturalNews.com)
Source: NaturalNews.com - November 17, 2017 Category: Consumer Health News Source Type: news

International Health Emergency Response Plan: Marburg Virus Disease
World Health Organization, Regional Office for Africa. 11/2017 This 15-page document details the confirmed outbreak of Marburg virus disease in Kween district, eastern Uganda, that was officially declared by the Ministry of Health on October 19, 2017. It discusses the response strategy, and how the World Health Organization, working closely with national partners and the Global Outbreak Alert and Response Network (GOARN), is supporting the ministries of health to stop the spread of the virus; care for those infected; and provide coordination and technical and operational response. (PDF) (Source: Disaster Lit: Resource Guid...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - November 17, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Marburg virus disease – Uganda and Kenya
Disease Outbreak News Uganda Kenya Marburg virus disease (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - November 15, 2017 Category: Infectious Diseases Tags: news Source Type: news

Uganda:Managing Marburg - How an Oddly Timed Outbreak is Testing Emergency Strategies
[Independent (Kampala)] Kampala -On Oct.11, a woman died in Chemuron village, Kween District in an Eastern Uganda. She had a fever, headache, and was bleeding from several places. Doctors attending to her had feared the worst and sent her samples for testing. A week later, on Oct.17, experts at Uganda Virus Research Institute (UVRI) confirmed the 50-year old woman had succumbed to a high mortality hemorrhagic fever - Marburg. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 8, 2017 Category: African Health Source Type: news

Black Death and incurable Marburg Virus now spreading across Africa's cities... world's medical system helpless to stop it
(Natural News) Africa is currently contending with two serious disease outbreaks. The pneumonic plague has been making headlines as it sweeps across Madagascar, but there are concerns about it are being eclipsed by a far more sinister threat: A rare and fatal virus known Marburg virus disease (MVD), which has now broken out in Uganda.... (Source: NaturalNews.com)
Source: NaturalNews.com - November 7, 2017 Category: Consumer Health News Source Type: news

Marburg virus disease – Uganda and Kenya
Update on Marburg virus disease outbreak in Uganda and Kenya, 7 November 2017 (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - November 7, 2017 Category: Infectious Diseases Tags: news Source Type: news

Virus 'similar' to Ebola has broken out in Uganda
Marburg virus disease, which kills up to 88 per cent of people it strikes, is considered to be one of the most deadly pathogens in existence. Five cases have been identified in Uganda. (Source: the Mail online | Health)
Source: the Mail online | Health - November 6, 2017 Category: Consumer Health News Source Type: news

Kenya:Kenya Monitors Family After Ugandan Dies of Marburg Virus
[East African] A family of seven in Trans Nzoia County western Kenya has been put under observation after a Ugandan who visited their homestead died of the highly contagious Marburg virus. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 2, 2017 Category: African Health Source Type: news

Tanzania:Dar es Salaam On Alert, Intensifies Testing for Marburg Vurus
[Daily News] Tanzanians have been alerted on Marburg outbreak in Eastern Uganda, with the government assuring of intensified defensive measures. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 2, 2017 Category: African Health Source Type: news

Tanzania:Dar es Salaam On Alert, Intensifies Testing for Marburg Virus
[Daily News] Tanzanians have been alerted on Marburg outbreak in Eastern Uganda, with the government assuring of intensified defensive measures. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 2, 2017 Category: African Health Source Type: news

Kenya:Trans Nzoia on Alert Over Suspected Marburg Virus Case
[Nation] Health officials in Trans Nzoia County have issued an alert of a suspected Marburg virus case in the region. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 1, 2017 Category: African Health Source Type: news

Kenya:Kenya on High Alert After a Suspected Marburg Case Near Uganda Border
[East African] Kenya is on high alert following a suspected case of the Ebola-like Marburg virus in the western Trans Nzoia County, which borders Uganda. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 1, 2017 Category: African Health Source Type: news

Deadly Marburg virus outbreak declared in Uganda
An outbreak of contagious and deadly Marburg virus disease in the Kween district of eastern Uganda was declared by the nation's Ministry of Health on October 19. (Source: CNN.com - Health)
Source: CNN.com - Health - October 31, 2017 Category: Consumer Health News Source Type: news

East Africa:WHO Releases $500,000 to Contain Plague, Marburg
[East African] Kenya and Tanzania are among counties identified by the World Health Organisation as likely hotspots for the plague that has ravaged Madagascar and a recent Marburg virus disease outbreak in eastern Uganda. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 29, 2017 Category: African Health Source Type: news

Kenya:WHO Advises Kenya to Bolster Efforts Against Disease Outbreaks
[Nation] Kenya is among the countries identified by the World Health Organization as likely hotspots for plague and Marburg outbreaks that have ravaged Madagascar and Uganda respectively. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 27, 2017 Category: African Health Source Type: news