Walter Reed Army Institute of Research begins phase 1 clinical trial of Marburg vaccine
(Walter Reed Army Institute of Research) WRAIR this week administered the first vaccine in a Phase 1 clinical trial to evaluate the safety and immunogenicity of a Marburg vaccine candidate in healthy adult volunteers. The WRAIR study evaluates the VRC-MARADC087-00-VP vaccine, developed by the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). The Marburg virus is in the same family as Ebola and causes severe hemorrhagic fever in humans. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 15, 2018 Category: Infectious Diseases Source Type: news

Mechanism of Marburg virus sexual transmission identified in nonhuman primates
(US Army Medical Research Institute of Infectious Diseases) Research by Army scientists elucidates the mechanism of sexual transmission of filoviruses, which have been shown to persist in the testes and other immune privileged sites. Sexual transmission of filoviruses was first reported in 1968 after an outbreak of Marburg virus disease and recently caused flare-ups of Ebola virus disease in the 2013-2016 outbreak. The team found that Marburg virus persists in seminiferous tubules and that Sertoli cells are the reservoir for the virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 30, 2018 Category: Infectious Diseases Source Type: news

Boston University lab gets shipment of Ebola, Marburg viruses
Researchers at Boston University ’s infectious disease lab received the first pathogens it's gotten under its new heightened designation: the Ebola and Marburg viruses. The National Emerging Infectious Diseases Laboratories received clearance from the Boston Public Health Commission in December to be upgraded to a Biosafety Leve l 4 facility – the 10th in the country. The designation was years in the making, and came after intense scrutiny by state, city and federal officials, including approval… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - August 2, 2018 Category: Health Management Authors: Jessica Bartlett Source Type: news

Boston University lab gets shipment of Ebola, Marburg viruses
Researchers at Boston University ’s infectious disease lab received the first pathogens it's gotten under its new heightened designation: the Ebola and Marburg viruses. The National Emerging Infectious Diseases Laboratories received clearance from the Boston Public Health Commission in December to be upgraded to a Biosafety Leve l 4 facility – the 10th in the country. The designation was years in the making, and came after intense scrutiny by state, city and federal officials, including approval… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 2, 2018 Category: Biotechnology Authors: Jessica Bartlett Source Type: news

Bats may have co-opted viral proteins produced by Ebola for immune function
(Cell Press) Approximately 18 million years ago, genes encoding viral proteins 35 (VP35s) integrated into the genomes of Myotis (mouse-eared) bats. Produced by the highly deadly Ebola and Marburg viruses, VP35s suppress the host immune system and play a critical role in the efficient replication and virulence of these filoviruses. A study publishing July 24 in Cell Reports sheds light on the potential functional role of these so-called non-retroviral integrated RNA viral sequences (NIRVs) in bats. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 24, 2018 Category: Infectious Diseases Source Type: news

Study of bat natural immunity to Marburg virus may shed light on human disease
(US Army Medical Research Institute of Infectious Diseases) Scientists examining the genome of Egyptian fruit bats, a natural reservoir for the deadly Marburg virus, have identified several immune-related genes that suggest bats deal with viral infections in a substantially different way than primates. Their research, published online today in the journal Cell, demonstrates that bats may be able to host viruses that are pathogenic in humans by tolerating -- rather than overcoming -- the infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 26, 2018 Category: Infectious Diseases Source Type: news

Uganda:Team Keeps Finding New Virusus - Researcher
[Independent (Kampala)] Kampala -The government response to the 2017 Marburg virus outbreak in Kween District, eastern Uganda cost Shs5.2billion. Most of that money came from donors. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 11, 2018 Category: African Health Source Type: news

Uganda:Team Keeps Finding New Viruses - Researcher
[Independent (Kampala)] Kampala -The government response to the 2017 Marburg virus outbreak in Kween District, eastern Uganda cost Shs5.2billion. Most of that money came from donors. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 11, 2018 Category: African Health Source Type: news

Annual Epidemiological Report for 2015: Ebola and Marburg Fevers
European Union, European Centre for Disease Prevention and Control. 01/2018 This four-page surveillance report is based on data for 2015 retrieved from The European Surveillance System (TESSy) on December 12, 2016, and additional information from epidemic intelligence. It states that no cases of Ebola viral hemorrhagic fever and Marburg hemorrhagic fever infections were reported in European Union/European Economic Area (EU/EEA) countries in 2015. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 3, 2018 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

How bats carry viruses without getting sick
(Cell Press) Bats are known to harbor highly pathogenic viruses like Ebola or Marburg and yet they do not show clinical signs of disease. In a paper published in the journal Cell Host& Microbe on February 22, scientists at the Wuhan Institute of Virology in China find that in bats, an antiviral immune pathway called the STING-interferon pathway is dampened, and bats can maintain just enough defense against illness without triggering a heightened immune reaction. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 22, 2018 Category: Infectious Diseases Source Type: news

2018 Annual Review of the Blueprint List of Priority Diseases
World Health Organization. 02/08/2018 This Web page provides the 2018 List of Priority Diseases, which include Ebola virus disease and Marburg virus disease, Lassa fever, Middle East respiratory syndrome coronavirus (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS), and Zika virus. Experts consider that given their potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines, there is an urgent need for accelerated research and development for these diseases. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 10, 2018 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

TSRI scientists discover workings of first promising Marburg virus treatment
(Scripps Research Institute) Scientists at The Scripps Research Institute have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 10, 2018 Category: Infectious Diseases Source Type: news

Researchers inhibit ebola virus
(University of Copenhagen The Faculty of Health and Medical Sciences) The incurable Ebola virus has long been feared due to its high mortality rate and danger of infection. Now researchers from the University of Copenhagen and Phillips Universit ä t Marburg have succeeded in inhibiting the virus in cell cultures. The researchers hope to be able to continue doing animal testing and developing an actual drug. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 29, 2017 Category: Infectious Diseases Source Type: news

Uganda:MSF Ends Its Intervention in Response to the Marburg Fever Outbreak
[MSF] Ugandan authorities have declared the end of the Marburg fever outbreak that has affected the eastern part of the country since October. MSF provided support to local authorities, in particular in case management capacity and epidemic surveillance. MSF, the Ugandan Ministry of Health and their partners have also introduced new tools which will improve case management in future haemorrhagic fever outbreaks. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 11, 2017 Category: African Health Source Type: news

Uganda:Uganda Declared Marburg Free
[Monitor] Kampala -The Ministry of Health has declared Uganda Marburg free. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 9, 2017 Category: African Health Source Type: news

Uganda says it has contained an outbreak of Marburg hemorrhagic fever
KAMPALA (Reuters) - Uganda said on Friday it had successfully contained an outbreak of the Marburg virus, a highly infectious haemorrhagic fever announced by officials on Oct. 19, which killed three people. (Source: Reuters: Health)
Source: Reuters: Health - December 8, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Uganda controls deadly Marburg fever outbreak, WHO says
Uganda controls deadly Marburg fever outbreak, World Health Organization says (Source: ABC News: Health)
Source: ABC News: Health - December 8, 2017 Category: Consumer Health News Tags: Health Source Type: news

Uganda ends Marburg virus disease outbreak
Uganda has successfully controlled an outbreak of Marburg virus disease and prevented its spread only weeks after it was first detected, the World Health Organization said on Friday (December 8). “Uganda has led an exemplary response. Health authorities and partners, with the support of WHO, were able to detect and control the spread of Marburg virus disease within a matter of weeks,” said Dr Matshidiso Moeti, WHO Regional Director for Africa. (Source: WHO news)
Source: WHO news - December 8, 2017 Category: International Medicine & Public Health Tags: marburg [subject], marburg haemorrhagic fever Source Type: news

New outbreak: Deadly virus, similar to Ebola, with NO treatment... now strikes Uganda
(Natural News) Uganda is in the middle of a health care crisis as the deadly Marburg virus has once again hit the African nation. Health chiefs have announced that the virus, which is clinically similar to the Ebola virus, has been detected in five cases. The reports note that an emergency Marburg virus screening is being carried... (Source: NaturalNews.com)
Source: NaturalNews.com - November 17, 2017 Category: Consumer Health News Source Type: news

International Health Emergency Response Plan: Marburg Virus Disease
World Health Organization, Regional Office for Africa. 11/2017 This 15-page document details the confirmed outbreak of Marburg virus disease in Kween district, eastern Uganda, that was officially declared by the Ministry of Health on October 19, 2017. It discusses the response strategy, and how the World Health Organization, working closely with national partners and the Global Outbreak Alert and Response Network (GOARN), is supporting the ministries of health to stop the spread of the virus; care for those infected; and provide coordination and technical and operational response. (PDF) (Source: Disaster Lit: Resource Guid...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - November 17, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Marburg virus disease – Uganda and Kenya
Disease Outbreak News Uganda Kenya Marburg virus disease (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - November 15, 2017 Category: Infectious Diseases Tags: news Source Type: news

Uganda:Managing Marburg - How an Oddly Timed Outbreak is Testing Emergency Strategies
[Independent (Kampala)] Kampala -On Oct.11, a woman died in Chemuron village, Kween District in an Eastern Uganda. She had a fever, headache, and was bleeding from several places. Doctors attending to her had feared the worst and sent her samples for testing. A week later, on Oct.17, experts at Uganda Virus Research Institute (UVRI) confirmed the 50-year old woman had succumbed to a high mortality hemorrhagic fever - Marburg. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 8, 2017 Category: African Health Source Type: news

Black Death and incurable Marburg Virus now spreading across Africa's cities... world's medical system helpless to stop it
(Natural News) Africa is currently contending with two serious disease outbreaks. The pneumonic plague has been making headlines as it sweeps across Madagascar, but there are concerns about it are being eclipsed by a far more sinister threat: A rare and fatal virus known Marburg virus disease (MVD), which has now broken out in Uganda.... (Source: NaturalNews.com)
Source: NaturalNews.com - November 7, 2017 Category: Consumer Health News Source Type: news

Marburg virus disease – Uganda and Kenya
Update on Marburg virus disease outbreak in Uganda and Kenya, 7 November 2017 (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - November 7, 2017 Category: Infectious Diseases Tags: news Source Type: news

Virus 'similar' to Ebola has broken out in Uganda
Marburg virus disease, which kills up to 88 per cent of people it strikes, is considered to be one of the most deadly pathogens in existence. Five cases have been identified in Uganda. (Source: the Mail online | Health)
Source: the Mail online | Health - November 6, 2017 Category: Consumer Health News Source Type: news

Kenya:Kenya Monitors Family After Ugandan Dies of Marburg Virus
[East African] A family of seven in Trans Nzoia County western Kenya has been put under observation after a Ugandan who visited their homestead died of the highly contagious Marburg virus. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 2, 2017 Category: African Health Source Type: news

Tanzania:Dar es Salaam On Alert, Intensifies Testing for Marburg Vurus
[Daily News] Tanzanians have been alerted on Marburg outbreak in Eastern Uganda, with the government assuring of intensified defensive measures. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 2, 2017 Category: African Health Source Type: news

Tanzania:Dar es Salaam On Alert, Intensifies Testing for Marburg Virus
[Daily News] Tanzanians have been alerted on Marburg outbreak in Eastern Uganda, with the government assuring of intensified defensive measures. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 2, 2017 Category: African Health Source Type: news

Kenya:Trans Nzoia on Alert Over Suspected Marburg Virus Case
[Nation] Health officials in Trans Nzoia County have issued an alert of a suspected Marburg virus case in the region. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 1, 2017 Category: African Health Source Type: news

Kenya:Kenya on High Alert After a Suspected Marburg Case Near Uganda Border
[East African] Kenya is on high alert following a suspected case of the Ebola-like Marburg virus in the western Trans Nzoia County, which borders Uganda. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 1, 2017 Category: African Health Source Type: news

Deadly Marburg virus outbreak declared in Uganda
An outbreak of contagious and deadly Marburg virus disease in the Kween district of eastern Uganda was declared by the nation's Ministry of Health on October 19. (Source: CNN.com - Health)
Source: CNN.com - Health - October 31, 2017 Category: Consumer Health News Source Type: news

East Africa:WHO Releases $500,000 to Contain Plague, Marburg
[East African] Kenya and Tanzania are among counties identified by the World Health Organisation as likely hotspots for the plague that has ravaged Madagascar and a recent Marburg virus disease outbreak in eastern Uganda. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 29, 2017 Category: African Health Source Type: news

Kenya:WHO Advises Kenya to Bolster Efforts Against Disease Outbreaks
[Nation] Kenya is among the countries identified by the World Health Organization as likely hotspots for plague and Marburg outbreaks that have ravaged Madagascar and Uganda respectively. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 27, 2017 Category: African Health Source Type: news

Uganda:Marburg Patient Who Went Into Hiding Dies
[Monitor] The Marburg patient who had gone into hiding has died. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 27, 2017 Category: African Health Source Type: news

Amid Marburg outbreak, Uganda hosts global health summit
Amid Marburg fever outbreak, Uganda hosts global summit on infectious diseases (Source: ABC News: Health)
Source: ABC News: Health - October 25, 2017 Category: Consumer Health News Tags: Health Source Type: news

Marburg virus disease – Uganda
On 17 October 2017, the Ugandan Ministry of Health notified WHO of a confirmed outbreak of Marburg virus disease in Kween District, Eastern Uganda. The Ministry for Health officially declared the outbreak on 19 October 2017. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - October 25, 2017 Category: Infectious Diseases Tags: news Source Type: news

Uganda:Global Health Security Meeting Must Work for All
[Monitor] Top scientists, academics and Health ministers or equivalents from around the world will this morning begin intense conversations in Kampala on how to guarantee global health security. The theme of the three-day symposium is: 'Security for all: Engaging communities, non-governmental organisations, and the private sector'. The theme and timing could not be more apt. Uganda is grappling with containing a Marburg outbreak in Sebei sub-region. The hazard zone straddles the Uganda-Kenya frontier, making cross-b (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 25, 2017 Category: African Health Source Type: news

Uganda:Man 'Wanted' for Deadly Virus Surveillance
[CAJ News] Kampala -THE disappearance of a man wanted for monitoring is stalling efforts to contain an outbreak of the deadly Marburg Virus Disease (MVD) in Uganda. He is a brother to two victims that have died of the disease, including a 50-year-old woman whom she transported to the hospital and took the body back home for burial. The World Health Organisation (WHO) Rapid Response team from the country office has reached Kween district east of Uganda, the epicentre of the outbreak but the disappearance of the man is cause fo (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 24, 2017 Category: African Health Source Type: news

Uganda:Halt Marburg in Its Tracks to Save Lives
[Monitor] The Health ministry has faced a few challenges in dealing with the latest epidemic to hit the country - Marburg disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 24, 2017 Category: African Health Source Type: news

Uganda:Caretaker of Marburg Patient Goes Into Hiding
[Monitor] KWEEN/KAMPALA -The task force helping to fight Marburg spread in Kween District, eastern Uganda has asked police to hunt for Joseph Cherungu, an adult of Kamwam Village, who has reportedly been one of the key caretakers of the last Marburg victim. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 24, 2017 Category: African Health Source Type: news

Marburg Haemorrhagic Fever
World Health Organization. 10/2017 This fact sheet provides information about Marburg hemorrhagic fever, also called Marburg virus disease, which is a severe, often fatal illness in humans. It discusses transmission, symptoms, persistent virus in people recovering from Marburg virus disease, diagnosis, treatment and vaccines, Marburg in animals, prevention and control, and controlling infection in healthcare settings. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - October 23, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Uganda Confirms One Death From Ebola-like Marburg Virus Uganda Confirms One Death From Ebola-like Marburg Virus
Uganda has confirmed one death from Marburg virus, a highly infectious hemorrhagic fever similar to Ebola, the health minister said on Thursday.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 20, 2017 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

WHO supports containment of rare virus on Uganda-Kenya border
(Source: WHO news)
Source: WHO news - October 20, 2017 Category: International Medicine & Public Health Tags: marburg [subject], marburg haemorrhagic fever, marburg [subject], marburg haemorrhagic fever, African Region [region], Press release [doctype], Uganda [country] Source Type: news

Uganda:Marburg Disease Alert - One Confirmed Dead in Kween
[Observer] Ministry of Health has confirmed an outbreak of the Marburg virus disease in the eastern district of Kween. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 20, 2017 Category: African Health Source Type: news

Marburg hemorrhagic fever kills 1 person in Uganda
Uganda's health minister says 1 person has recently died Marburg, a highly infectious disease that, like Ebola, manifests as a viral hemorrhagic fever (Source: ABC News: Health)
Source: ABC News: Health - October 19, 2017 Category: Consumer Health News Tags: Health Source Type: news

Uganda confirms one death from Ebola-like Marburg virus
KAMPALA (Reuters) - Uganda has confirmed one death from Marburg virus, a highly infectious hemorrhagic fever similar to Ebola, the health minister said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Uganda confirms one case of Ebola-like Marburg virus
NAIROBI (Reuters) - Uganda has confirmed one case of Marburg virus, a highly infectious hemorrhagic fever similar to Ebola, the health minister said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Uganda:Marburg Fever Kills Two
[Monitor] Kampala -Government epidemiologists have confirmed an outbreak of Marburg haemorrhagic fever case in the eastern district of Kween. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 19, 2017 Category: African Health Source Type: news

Inserting a cannula into a vein
(Deutsches Aerzteblatt International) Patients who are given a local anesthetic before having a venous cannula inserted have a clearly reduced sensation of pain when larger gauge cannulas are used. Compared with intradermal lidocaine infusion, the use of vapocoolant spray has the advantage that the rate of venepuncture failures is lower. This is the conclusion reached by Dirk R ü sch and coauthors from Marburg University based on a randomized controlled trial. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 13, 2017 Category: International Medicine & Public Health Source Type: news