Incidence of chemotherapy-related cardiac dysfunction in cancer patients
CONCLUSION: Our meta-analysis unveiled a definitive overall incidence rate of chemotherapy-related cardiac dysfunction in cancer patients. In addition, it was found that the risk of developing this condition escalates within the initial 6 months postchemotherapy, subsequently tapering off to become statistically insignificant after a duration of 6 years.PMID:38634453 | PMC:PMC11024952 | DOI:10.1002/clc.24269 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 18, 2024 Category: Cancer & Oncology Authors: Hai-Wei Deng Rui Fan Yuan-Sheng Zhai Jie Li Zhi-Bin Huang Long-Yun Peng Source Type: research
Incidence of chemotherapy-related cardiac dysfunction in cancer patients
CONCLUSION: Our meta-analysis unveiled a definitive overall incidence rate of chemotherapy-related cardiac dysfunction in cancer patients. In addition, it was found that the risk of developing this condition escalates within the initial 6 months postchemotherapy, subsequently tapering off to become statistically insignificant after a duration of 6 years.PMID:38634453 | PMC:PMC11024952 | DOI:10.1002/clc.24269 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 18, 2024 Category: Cancer & Oncology Authors: Hai-Wei Deng Rui Fan Yuan-Sheng Zhai Jie Li Zhi-Bin Huang Long-Yun Peng Source Type: research
LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy
Immunobiology. 2024 Apr 6;229(3):152799. doi: 10.1016/j.imbio.2024.152799. Online ahead of print.ABSTRACTWe hereby intend to further explore and confirm the underlying mechanism of Small nucleolar RNA Host Gene 1 (SNHG1) in osteoarthritis (OA). For in vitro assays, OA was induced in primary chondrocytes with interleukin-1β (IL-1β) treatment; while for in vivo tests, OA model was established in mice using the destabilization of the medial meniscus (DMM) method. Cell viability and apoptosis were assessed with MTT and flow cytometry assays, respectively. Cartilage tissue was stained by Safranin-O/Fast Green Staining. The mR...
Source: Immunobiology - April 18, 2024 Category: Allergy & Immunology Authors: Qiushi Wang Jie Yang Rui Pan Zhengang Zha Source Type: research
Incidence of chemotherapy-related cardiac dysfunction in cancer patients
CONCLUSION: Our meta-analysis unveiled a definitive overall incidence rate of chemotherapy-related cardiac dysfunction in cancer patients. In addition, it was found that the risk of developing this condition escalates within the initial 6 months postchemotherapy, subsequently tapering off to become statistically insignificant after a duration of 6 years.PMID:38634453 | DOI:10.1002/clc.24269 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 18, 2024 Category: Cancer & Oncology Authors: Hai-Wei Deng Rui Fan Yuan-Sheng Zhai Jie Li Zhi-Bin Huang Long-Yun Peng Source Type: research
LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy
Immunobiology. 2024 Apr 6;229(3):152799. doi: 10.1016/j.imbio.2024.152799. Online ahead of print.ABSTRACTWe hereby intend to further explore and confirm the underlying mechanism of Small nucleolar RNA Host Gene 1 (SNHG1) in osteoarthritis (OA). For in vitro assays, OA was induced in primary chondrocytes with interleukin-1β (IL-1β) treatment; while for in vivo tests, OA model was established in mice using the destabilization of the medial meniscus (DMM) method. Cell viability and apoptosis were assessed with MTT and flow cytometry assays, respectively. Cartilage tissue was stained by Safranin-O/Fast Green Staining. The mR...
Source: Immunobiology - April 18, 2024 Category: Allergy & Immunology Authors: Qiushi Wang Jie Yang Rui Pan Zhengang Zha Source Type: research
CD58 alterations govern antitumor immune responses by inducing PD-L1 and IDO in diffuse large B-cell lymphoma
Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2874. Online ahead of print.ABSTRACTRecurrent abnormalities in immune surveillance-related genes affect the progression of diffuse large B-cell lymphoma (DLBCL) and modulate the response to therapeutic interventions. CD58 interacts with the CD2 receptor on T cells and natural killer (NK) cells and is recurrently mutated and deleted in DLBCL, suggesting it may play a role in regulating antitumor immunity. Herein, we comprehensively analyzed the genomic characteristics of CD58 through targeted next-generation sequencing, RNA-sequencing, whole-exome sequencing, and single...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Xiyue Xu Yidan Zhang Yaxiao Lu Xiaoyan Zhang Cuicui Zhao Jiesong Wang Qingpei Guan Yingfang Feng Meng Gao Jingwei Yu Zheng Song Xia Liu Zahra Golchehre Lanfang Li Weicheng Ren Qiang Pan-Hammarstr öm Huilai Zhang Xianhuo Wang Source Type: research
Not all central nervous system lymphomas are created equal
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285388. Online ahead of print.ABSTRACTNot available.PMID:38634145 | DOI:10.3324/haematol.2024.285388 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Alvaro J Alencar Juan Pablo Alderuccio Source Type: research
< em > TP3 < /em > binding domain mutations are bad news in Burkitt lymphoma
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285213. Online ahead of print.ABSTRACTNot available.PMID:38634119 | DOI:10.3324/haematol.2024.285213 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Mitchell S Cairo Source Type: research
Primary cutaneous anaplastic large-cell lymphoma resembling infratemporal space infection: a case report
Primary cutaneous anaplastic large-cell lymphoma (PC-ALCL) is a rare T-cell lymphoma belonging to the CD30 + T-cell lymphoproliferative disorders. The case of PC-ALCL in the temporal region is exceedingly rare... (Source: BMC Oral Health)
Source: BMC Oral Health - April 18, 2024 Category: Dentistry Authors: Xiaohan Yan, Wenhao Ren, Shaoming Li, Zhuang Zhu, Ling Gao and Keqian Zhi Tags: Case Report Source Type: research
Chlamydia psittaci Screening of Animal Workers from Argentina Exposed to Carrier Birds
AbstractDifferent syndromes are involved in human psittacosis (flu-like syndrome, atypical pneumonia up to lacrimal gland lymphoma). Diagnostic methods include serology, culture, and PCR. The rate ofChlamydia psittaci (Cp) positive tests among exposed workers is still unknown. Our study aimed to assess the rate of positive tests among workers who have contact with carrier birds in natural reserves from Buenos Aires, Argentina. Secondary aims were to analyze risk factors linked to these outcomes and the occurrence of signs that suggest psittacosis. Nasopharyngeal swabs and serum pairs were collected from employees who had i...
Source: EcoHealth - April 18, 2024 Category: Environmental Health Source Type: research
Incidence rates of the most common canine tumors based on data from the Swiss Canine Cancer Registry (2008 to 2020)
In conclusion, the calculated IRs and IRRs revealed previously unknown predisposing factors, including novel breed-specific suscepti bilities. The results may have implications for cancer screening, diagnostic work-up, breeding management and oncologic and translational research. (Source: PLoS One)
Source: PLoS One - April 18, 2024 Category: Biomedical Science Authors: Elena Sophie Dhein Source Type: research
Changes in income and employment after diagnosis among patients with multiple myeloma in The Netherlands
Due to new treatment options, survival rates in multiple myeloma (MM) are improving. Consequently, maintaining work and income is becoming more important for patients and society. Therefore, we aimed to explore the change in income and employment in patients with MM. (Source: Clinical Lymphoma, Myeloma and Leukemia)
Source: Clinical Lymphoma, Myeloma and Leukemia - April 18, 2024 Category: Hematology Authors: Christine Bennink, Mirian Brink, Saskia F.A. Duijts, Hans Scheurer, Pieter Sonneveld, Hedwig M. Blommestein Tags: Original Study Source Type: research
Primary lymphoma of the female genital tract masquerading as gynecological malignancy
Primary lymphoma of the female genital tract (PLFGT) is a rare malignant tumor in the female reproductive system, with a low incidence and few clinical reports. The aim of this study is to report our instituti... (Source: BMC Women's Health)
Source: BMC Women's Health - April 18, 2024 Category: OBGYN Authors: Suhua Shi, Wuan Li, Guantai Ni, Jin Ding, Yinhua Liu, Haixing Wu, Zhen Zhang and Zhimin Ding Tags: Research Source Type: research
Sociodemographic factors and Child Opportunity Index disparities associated with missed care opportunities in pediatric patients with lymphoma and leukemia referred for FDG-PET/CT
ConclusionChildren with lymphoma/leukemia, living in zip codes with very low or low COI, and who identified as Black/African American non-Hispanic/Latino experienced more MCOs. Our study supports the need to address intersecting sociodemographic, neighborhood, and health system factors that will improve equitable access to necessary healthcare imaging for children.Graphical abstract (Source: Pediatric Radiology)
Source: Pediatric Radiology - April 18, 2024 Category: Radiology Source Type: research
Second line therapy in multiple myeloma: A SEER Medicare analysis
Introduction: The therapeutic landscape in relapsed/refractory multiple myeloma (RRMM) has changed rapidly, with twenty-two drug approvals since 2012. We characterized population-level trends in RRMM therapy selection, survival and cost outcomes associated with RRMM treatment over time.Materials and Methods: Our cohort included adults diagnosed with multiple myeloma (MM) in the SEER-Medicare database from 2007 – 2017 who received at least one antimyeloma agent. MM-directed therapies and lines of therapy were identified. (Source: Clinical Lymphoma, Myeloma and Leukemia)
Source: Clinical Lymphoma, Myeloma and Leukemia - April 18, 2024 Category: Hematology Authors: Matthew R LeBlanc, Xi Zhou, Christopher D Baggett, Sascha Tuchman, Christopher E Jensen, Samuel Rubinstein Tags: Original Study Source Type: research
