Early discoid lupus onset protective against nephritis
BOSTON - Among 839 patients with systemic lupus erythematosus (SLE) and no evidence of lupus nephritis at the time of diagnosis, the presence of discoid lupus erythematosus (DLE) at SLE onset was associated with a 64% reduction in risk for developing lupus nephritis. “Our data suggest that while...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)
Source: Skin and Allergy News - December 7, 2014 Category: Dermatology Tags: FPN Conferences IMN Conferences RHEUM Conference News SAN Conference News RHEUM News RHEUM Lupus/Connective Tissue Diseases IMN News IMN Dermatology Source Type: news

IT HAPPENED TO ME: I Temporarily Had A Physical Disability
By Julia Reinstein As a person who has been able-bodied my whole life, I thought I was having one of those nightmares where you can't move or run away. It took me half an hour to realize that I was, in fact, awake. This was real. It was the spring of my sophomore year of college when I contracted Löfgren syndrome, an acute autoimmune disease that attacked the fat cells in my joints, particularly my knees. My legs swelled up like tree trunks and I broke out in nasty red bumps that felt hot to the touch. Every morning, I would wake up with legs so stiff and pained that I would only gain the strength to walk after seve...
Source: Healthy Living - The Huffington Post - December 4, 2014 Category: Consumer Health News Source Type: news

Cold hands: Could it be Raynaud’s?
I used to enjoy cold weather and cold-weather activities. Not anymore. These days I find it harder and harder to keep my hands warm when I’m outside, even with an excellent pair of gloves. Sometimes my fingers turn white and become numb. Those are the hallmarks of Raynaud’s syndrome (or disease or phenomenon). Named after the French physician who first described it in 1862, Raynaud’s is a problem in the body’s arteries. In most people with Raynaud’s, small arteries that bring oxygen-rich blood to the fingers spasm and close down in response to cold or stress. This reduces or cuts off blood flo...
Source: New Harvard Health Information - December 3, 2014 Category: Consumer Health News Authors: Patrick J. Skerrett Tags: Men's Health Pain Management Women's Health cold hands Raynaud's syndrome Source Type: news

Heart Rate Variability New Window in Lupus Disease ActivityHeart Rate Variability New Window in Lupus Disease Activity
Changes in heart rate might provide a noninvasive glimpse into underlying disease activity in patients with systemic lupus erythematosus. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 1, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

George Tsokos, M.D., honored by Lupus Foundation and American College of Rheumatology
(Beth Israel Deaconess Medical Center) Tsokos, Chief of Rheumatology at Beth Israel Deaconess Medical Center, is honored for investigations into the origins of lupus which have led to the discovery of new therapeutic targets. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2014 Category: Global & Universal Source Type: news

Eczema May Hike Lupus Risk in Kids
(MedPage Today) -- SLE incidence rate tied to severity of atopic dermatitis. (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - November 20, 2014 Category: Dermatology Source Type: news

BP Still High With Lupus Nephritis in Remission
(MedPage Today) -- Aggressive treatment important to achieve complete remission, prevent relapses. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 20, 2014 Category: Cardiology Source Type: news

ACR: Anti-IL-6 Shows Promise in Lupus
(MedPage Today) -- Efficacy signal seen in phase II trial. (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 20, 2014 Category: Journals (General) Source Type: news

ACR: New Tx Option in Lupus?
(MedPage Today) -- A monoclonal antibody that binds to interferon-alpha showed benefits in a phase IIb trial. (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 20, 2014 Category: Journals (General) Source Type: news

Pneumococcal Vax May Benefit SLE Patients
(MedPage Today) -- Lung infection risk a serious issue in lupus. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - November 18, 2014 Category: Infectious Diseases Source Type: news

Cardiovascular Disease a Leading Cause of Death in LupusCardiovascular Disease a Leading Cause of Death in Lupus
A 10-year study in almost 1000 patients examines the causes of death in patients with lupus. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - November 18, 2014 Category: Rheumatology Tags: Rheumatology Viewpoint Source Type: news

8 Rare 'House, M.D.' Cases That Can Actually Happen (And How To Avoid Them)
"House, M.D.," starring Hugh Laurie as a pill-popping genius, was conceived as the medical version of "Sherlock Holmes" and ran for eight seasons on Fox. Sunday, Nov. 16, marked the 10-year anniversary of the premiere. Though it's easy to look back on the show and focus on some of the unbelievable details of the cases, it might surprise you to learn that "House" was actually much more realistic than you thought. Yeah, the odds of all these rare medical cases coming to one hospital in New Jersey are pretty slim, but a variety of sources -- including Andrew Holtz, former CNN Medical Corresponde...
Source: Science - The Huffington Post - November 17, 2014 Category: Science Source Type: news

AstraZeneca lupus drug produces positive results in trial
An experimental lupus drug from AstraZeneca significantly improved the symptoms of lupus in a mid-stage clinical trial. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 17, 2014 Category: Pharmaceuticals Source Type: news

AstraZeneca lupus drug produces positive results in trial
LONDON (Reuters) - An experimental lupus drug from AstraZeneca significantly improved the symptoms of lupus in a mid-stage clinical trial, boosting prospects for a medicine the company believes could become a major seller. (Source: Reuters: Health)
Source: Reuters: Health - November 17, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Living With Lupus: Mayo Clinic Radio Health Minute
In this Mayo Clinic Radio Health Minute, Dr. Vai Chowdhary comments on living with lupus. To listen, click the link below. Living with Lupus (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 17, 2014 Category: Databases & Libraries Source Type: news

Lupus Nephritis: Multidrug Induction Ups Complete Responses Lupus Nephritis: Multidrug Induction Ups Complete Responses
A combination of tacrolimus, mycophenolate mofetil, and steroid resulted in higher remission rates than cyclophosphamide plus steroid. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

Umbilical Cord Mesenchymal Stem Cells in SLE TreatmentUmbilical Cord Mesenchymal Stem Cells in SLE Treatment
Could umbilical cord mesenchymal stem cell transplantation be an effective treatment option for treatment-refractory systemic lupus? Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 12, 2014 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

133 Organizations Ask Congress to Close the Innovation Deficit
Dear Member of Congress: The 133 undersigned national business, higher education, scientific, patient, and other organizations write to strongly urge you to pass an omnibus FY2015 appropriations bill this year that includes increased investments in scientific research and higher education needed to help close our nation's innovation deficit. Members of the Senate and House from both political parties have highlighted the need to address the innovation deficit. Congress has already taken some preliminary steps in this direction. In most instances, individual appropriations bills considered by the House and Senate Appropri...
Source: ActionBioscience - November 12, 2014 Category: Science Authors: Julie Palakovich Carr Source Type: news

133 Organizations Ask Congress to Close the Innovation Deficit
Dear Member of Congress: The 133 undersigned national business, higher education, scientific, patient, and other organizations write to strongly urge you to pass an omnibus FY2015 appropriations bill this year that includes increased investments in scientific research and higher education needed to help close our nation's innovation deficit. Members of the Senate and House from both political parties have highlighted the need to address the innovation deficit. Congress has already taken some preliminary steps in this direction. In most instances, individual appropriations bills considered by the House and Senate Appropri...
Source: ActionBioscience - November 12, 2014 Category: Biology Authors: Julie Palakovich Carr Source Type: news

Hitting Multiple Targets Is Winning Strategy in LN
(MedPage Today) -- Immunosuppressants improve the rate of complete remission in patients with lupus nephritis. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 11, 2014 Category: Rheumatology Source Type: news

Drug Combo Helps Lupus-Related Kidney Condition
Title: Drug Combo Helps Lupus-Related Kidney ConditionCategory: Health NewsCreated: 11/10/2014 12:00:00 AMLast Editorial Review: 11/11/2014 12:00:00 AM (Source: MedicineNet Crohn's Disease General)
Source: MedicineNet Crohn's Disease General - November 11, 2014 Category: Gastroenterology Source Type: news

Systemic Lupus Erythematosus Mortality Down Since 1968
However, SLE mortality is still higher than non - SLE mortality; sex, racial, regional disparities exist (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Family Medicine, Geriatrics, Internal Medicine, Nephrology, Neurology, Pulmonology, Rheumatology, Journal, Source Type: news

Rheumatic Diseases Associated With Increased Dementia Risk
Statistical significance in Sjögren's syndrome, lupus, OA in females; SS, psoriatic arthritis, OA in males (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - November 11, 2014 Category: Psychiatry Tags: Dermatology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Neurology, Nursing, Pathology, Psychiatry, Rheumatology, Anesthesiology & amp; Pain, Journal, Source Type: news

Lupus Is a Leading Cause of Death in Young Women
Death from lupus ranked 10th in women 15 to 24 years, 14th in those aged 25 to 34 and 35 to 44 years (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Nephrology, Pulmonology, Rheumatology, Journal, Source Type: news

Drug Combo Helps Lupus-Related Kidney Condition
Half of those taking three medications achieved full remission, study reports (Source: WebMD Health)
Source: WebMD Health - November 10, 2014 Category: Consumer Health News Source Type: news

Drug Combo Helps Lupus-Related Kidney Condition
Half of those taking three medications achieved full remission, study reports Source: HealthDay Related MedlinePlus Pages: Kidney Diseases, Lupus, Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 10, 2014 Category: Consumer Health News Source Type: news

New Treatments, Guidelines, and the Microbiome at ACR 2014New Treatments, Guidelines, and the Microbiome at ACR 2014
The American College of Rheumatology (ACR) meeting will feature cutting-edge research in ankylosing spondylitis, psoriatic arthritis, lupus, and the role of the microbiome in autoimmune diseases. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

On Being Fat
I am fat. This fact cannot be disputed. I am also intelligent, educated and successful. To look at me, one might never guess that I am a successful director at a large corporation or that I gave up a child for adoption or that I survived kidney failure and a lifesaving kidney transplant. You probably also would not guess that I speak Arabic and was an interpreter on an archaeology dig in Syria. Would you guess I have been married twice and that I was an accomplished athlete? I have many stories, but because I am fat, you may never know these things about me. You see, I, like many others like me, endure one of the few rem...
Source: Healthy Living - The Huffington Post - November 7, 2014 Category: Consumer Health News Source Type: news

A matter of life and death: Cell death proteins key to fighting disease
key steps involved in programmed cell death have been uncovered by researchers, offering new targets for the treatment of diseases including lupus, cancers and neurodegenerative diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 31, 2014 Category: Science Source Type: news

A matter of life and death: Cell death proteins key to fighting disease
(Walter and Eliza Hall Institute) Melbourne researchers have uncovered key steps involved in programmed cell death, offering new targets for the treatment of diseases including lupus, cancers and neurodegenerative diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 30, 2014 Category: Cancer & Oncology Source Type: news

Study suggests altering gut bacteria might mitigate lupus
(American Society for Microbiology) Lactobacillus species, commonly seen in yogurt cultures, correlate, in the guts of mouse models, with mitigation of lupus symptoms, while Lachnospiraceae, a type of Clostridia, correlate with worsening, according to research published ahead of print in Applied and Environmental Microbiology. 'Our results suggest that the same investigation should be performed in human subjects with lupus,' says principal investigator Xin Luo of Virginia Tech, Blacksburg, VA. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 20, 2014 Category: Global & Universal Source Type: news

African Americans and Lupus: Mayo Clinic Radio Health Minute
Ethnicity is a risk factor in many diseases.  In this Mayo Clinic Radio Health Minute, Dr. Eric Matteson comments on a recent study that looked at African Americans and Lupus. To listen, click the link below. African Americans and Lupus (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 9, 2014 Category: Databases & Libraries Source Type: news

Transplant Delay Not Needed in Lupus Nephritis
(MedPage Today) -- Message: don't wait for lupus symptoms to recede when transplant is indicated. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - October 6, 2014 Category: Endocrinology Source Type: news

Lupus Nephritis: Delay May Increase Graft Failure Risk in ERSD Lupus Nephritis: Delay May Increase Graft Failure Risk in ERSD
White patients with end-stage renal disease whose kidney transplant was delayed by more than 3 months because of their lupus were at 25% to 37% increased risk of experiencing graft failure. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 2, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Lupus Nephritis: Delay May Increase Graft Failure Risk in ESRDLupus Nephritis: Delay May Increase Graft Failure Risk in ESRD
White patients with end-stage renal disease whose kidney transplant was delayed by more than 3 months because of their lupus were at 25% to 37% increased risk of experiencing graft failure. Medscape Medical News (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - October 2, 2014 Category: Urology & Nephrology Tags: Nephrology News Source Type: news

Eli Lilly stops development of lupus drug; XTL shares soar
(Reuters) - Eli Lilly and Co said it would stop the development of its drug to treat the autoimmune disorder lupus, after it was found to be not effective enough in late-stage trials. (Source: Reuters: Health)
Source: Reuters: Health - October 2, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Eli Lilly to drop development of lupus drug
Lupus is a condition in which the body's immune system starts attacking healthy tissues and causes inflammation, pain, and damage. (Source: The Economic Times)
Source: The Economic Times - October 2, 2014 Category: Consumer Health News Source Type: news

Possible New Plant Extract Lupus Treatment with No Side Effects
Lupus, or systemic lupus erythematosus, is a progressive, degenerative disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. Symptoms range from debilitating pain and fatigue to organ failure and a host of other impairments. An estimated 1.5 million Americans, and at least five million people worldwide, have a form of lupus. (Source: Disabled World)
Source: Disabled World - September 26, 2014 Category: Disability Tags: Lupus Source Type: news

Prospects for a Peptide Vaccine for Human LupusProspects for a Peptide Vaccine for Human Lupus
What features are needed in an effective lupus vaccine, and what are the challenges to developing one? International Journal of Clinical Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 26, 2014 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Autoimmune diseases, chronic inflammations: Advancing research
Multiple sclerosis, type 1 diabetes and lupus are autoimmune diseases in which the immune cells can no longer differentiate between friend and foe and thus attack the body's own tissue. Here, the immunoproteasome, which supplies the immune system with information on processes within the cell, plays a central role. Chemists have now discovered a way to inhibit its functionality, thereby laying the foundation for possible optimizations of existing medications. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 25, 2014 Category: Science Source Type: news

Spot on against autoimmune diseases and chronic inflammations
(Technische Universitaet Muenchen) Multiple sclerosis, type 1 diabetes and lupus are autoimmune diseases in which the immune cells can no longer differentiate between friend and foe and thus attack the body's own tissue. Here, the immunoproteasome, which supplies the immune system with information on processes within the cell, plays a central role. Chemists at Technische Universität München have now discovered a way to inhibit its functionality, thereby laying the foundation for possible optimizations of existing medications. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 25, 2014 Category: Biology Source Type: news

NIH announces network to accelerate medicines for rheumatoid arthritis and lupus
Partnership includes support from industry and non-profits. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 24, 2014 Category: American Health Source Type: news

Findings give hope to plant extract as possible lupus treatment
(University of Houston) Lupus is a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. New findings by a biomedical engineer and his team at the University of Houston raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments for this disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 24, 2014 Category: Global & Universal Source Type: news

NIH announces network to accelerate medicines for rheumatoid arthritis and lupus
(NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases) The National Institutes of Health has awarded grants to 11 research groups across the United States to establish the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus Network. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 24, 2014 Category: Global & Universal Source Type: news

The Pathogenesis, Diagnosis and Treatment of Lupus NephritisThe Pathogenesis, Diagnosis and Treatment of Lupus Nephritis
Get updated on the pathogenesis, diagnosis, and treatment of lupus nephritis. Current Opinion in Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2014 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

RheumShorts: Kineret, Shingles Vax, Home Rehab (CME/CE)
(MedPage Today) -- Recently published studies in rheumatology covered use of anakinra (Kineret) in pregnancy, varicella-zoster vaccines in lupus patients, and home exercise after knee replacement. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 18, 2014 Category: Rheumatology Source Type: news

Math model designed to replace invasive kidney biopsy for lupus patients
Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. The model could also be used to monitor the effectiveness of experimental treatments for inflammation and fibrosis, researchers say. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 17, 2014 Category: Science Source Type: news

Math model designed to replace invasive kidney biopsy for lupus patients
(Ohio State University) Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2014 Category: Global & Universal Source Type: news

RheumShorts: Pediatric Update (CME/CE)
(MedPage Today) -- This week several studies have focused on rheumatologic disorders among young patients -- depression and anxiety in systemic lupus erythematosus and maternal smoking and jaw involvement in juvenile idiopathic arthritis. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - September 12, 2014 Category: Pediatrics Source Type: news