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Rituxan in Lupus: Responses Vary
(MedPage Today) -- Almost 60% improved at 3 months, yet 20% worsened at 6 months. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 30, 2015 Category: Primary Care Source Type: news

Being a victim or an aggressor: Different functions of triadic post-conflict interactions in wolves (Canis lupus lupus) - Cordoni G, Palagi E.
Animals adopt different behavioral strategies to cope with the conflict of interests coming from the competition over limited resources. Starting from the study on chimpanzees, post-conflict third-party affiliation (the affiliative contact provided by a th... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - April 28, 2015 Category: Global & Universal Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Male Fetal Cells May Protect Women With Lupus Nephritis (CME/CE)
(MedPage Today) -- SLE female patients previously pregnant with male fetuses had better renal function. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - April 24, 2015 Category: Rheumatology Source Type: news

Researchers will evaluate ustekinumab’s ability to treat lupus
The effectiveness of treating lupus with a drug approved for treating plaque psoriasis and active psoriatic arthritis will be tested in a clinical study. The study, which will be conducted by the Alliance for Lupus Research and Janssen Research & Development, LLC, will evaluate the drug,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 23, 2015 Category: Dermatology Tags: RHEUM Lupus/Connective Tissue Diseases RHEUM News SAN Clinical News SAN News SAN Psoriasis Source Type: news

Re-engineering lupus into a cancer killer
Researchers have devised a way to re-engineer lupus antibodies to turn them into potential cancer killers. Lupus is a chronic inflammatory disease that occurs when the immune system attacks its own organs, tissues, or joints. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 21, 2015 Category: Science Source Type: news

Haematological Manifestations of LupusHaematological Manifestations of Lupus
Which hematological abnormalities are common findings in patients with SLE? Lupus Science & Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 20, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

What Causes Bullae?
Discussion Bullae are fluid-filled epidermal lesions that are filled with serous or seropurulent fluid. They are> 1 cm in diameter and often easily rupture due to their thin walls. The differential diagnosis is different for bullae than for vesicular lesions with bullae being often more worrisome. However there is overlap and vesicular diseases can become large enough to be bullae. Drug toxicity and genetic problems are also more common in bullae whereas vesicles are more often caused by infectious diseases. Potentially life threatening conditions such as toxic epidermal necrolysis syndrome, Stevens Johnson syndrome or...
Source: PediatricEducation.org - April 20, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Vitamin D Tracks Systemic Lupus Erythematosus Activity (CME/CE)
(MedPage Today) -- Study first in Southern Hemisphere to examine role of vitamin D in SLE disease activity (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 16, 2015 Category: Primary Care Source Type: news

Azathioprine and Mycophenolate Mofetil Comparable in Lupus NephritisAzathioprine and Mycophenolate Mofetil Comparable in Lupus Nephritis
In a 10-year follow-up study, European investigators found no difference in long-term outcomes between patients given mycophenolate mofetil (MMF) or azathioprine as maintenance therapy for proliferative lupus nephritis. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 14, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news

TWEAK/Fn14 interactions associated with cutaneous lupus pathogenesis
Interactions between TNF-like weak inducer of apoptosis and its receptor Fn14 are significantly associated with the pathogenesis of cutaneous lupus, according to Dr. Jessica Doerner and her associates. Treating murine keratinocytes with TWEAK stimulated both RANTES, a T cell important in the... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 7, 2015 Category: Dermatology Tags: SAN Journals SAN Clinical News SAN News SAN Atopic Dermatitis RHEUM Journal RHEUM News RHEUM Lupus/Connective Tissue Diseases Source Type: news

Study identifies protein that triggers lupus-associated immune system activation
(Massachusetts General Hospital) Massachusetts General Hospital investigators have found that a protein that regulates certain cells in the innate immune system -- the body's first line of defense against infection -- activates a molecular pathway known to be associated with the autoimmune disorder systemic lupus erythematosus and that the protein's activity is required for the development of lupus symptoms in a mouse model of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 6, 2015 Category: Global & Universal Source Type: news

Mood Disorders Hamper Quality of Life in SLE (CME/CE)
(MedPage Today) -- Some mood disorders may respond to systemic lupus erythematosus therapies over time. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 28, 2015 Category: Primary Care Source Type: news

Vitamin D Won't Diminish Interferon-Inducible Gene Expression in SLE (CME/CE)
(MedPage Today) -- Supplements don't affect gene expression in lupus patients. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 27, 2015 Category: Primary Care Source Type: news

NYU Leads the Way in Lupus Pregnancy (CME/CE)
(MedPage Today) -- Focus on risk factors for adverse outcomes and preventing congenital heart block. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 26, 2015 Category: Cardiology Source Type: news

Lupus: How does it affect the kidneys?
(Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - March 26, 2015 Category: Consumer Health News Source Type: news

Disease Damage Rises Steadily in Lupus (CME/CE)
(MedPage Today) -- Contributing factors included steroid use, disease activity, and hypertension. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 24, 2015 Category: Rheumatology Source Type: news

The Untold Story Of How Dogs Became Our Best Friends
Dogs and humans have been BFFs for a very long time -- at least 10,000 years. No surprise there. But have you ever wondered just how dogs and other animals got domesticated, and why? And how today's domesticated animals differ from their wild predecessors? The story is even more complicated than you might imagine. To learn more about how man's best friend came to be -- and how dogs changed the course of human history -- check out the video above, and/or read the transcript below. Don't forget to leave your thoughts in the comments. Talk nerdy to me! CLICK HERE FOR FULL TRANSCRIPT They’re our best friends! Aro...
Source: Science - The Huffington Post - March 23, 2015 Category: Science Source Type: news

'Ground Zero' Workers At Risk of Autoimmune Diseases
Prolonged exposure linked to rheumatoid arthritis, lupus Source: HealthDay Related MedlinePlus Pages: Autoimmune Diseases, Occupational Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 19, 2015 Category: Consumer Health News Source Type: news

Lupus Nephritis Histology Predicts Long-Term Outcomes (CME/CE)
(MedPage Today) -- Class IV disease associated with poorer 5-year remission rates. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 13, 2015 Category: Primary Care Source Type: news

High-Dose Steroids May Trigger Organ Damage in Lupus (CME/CE)
(MedPage Today) -- Organ damage risk doubled with daily doses of 20 mg prednisone. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 12, 2015 Category: Primary Care Source Type: news

Two Regimens Equivalent in Lupus Nephritis (CME/CE)
(MedPage Today) -- 10-year study confirms: it's a toss-up between mycophenolate mofetil and azathioprine. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 11, 2015 Category: Primary Care Source Type: news

Lupus: Hospitalizations for Infections Continue to Rise (CME/CE)
(MedPage Today) -- Skin infections and sepsis top list (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 4, 2015 Category: Infectious Diseases Source Type: news

Systemic Lupus Erythematosus: Which Drugs and When?Systemic Lupus Erythematosus: Which Drugs and When?
Treatment options for SLE are continuing to improve. Which therapies are most promising? International Journal of Clinical Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 27, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Hep C Tx Benefits HCV-Positive Lupus Patients (CME/CE)
(MedPage Today) -- But glucocorticosteroids won't trigger hepatitis reactivation, suggests this study. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - February 26, 2015 Category: Gastroenterology Source Type: news

Firstborns May Have Lower SLE Risk (CME/CE)
(MedPage Today) -- Swedish study found no evidence that birth weight impacts odds for systemic lupus erythematosus. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - February 24, 2015 Category: Pediatrics Source Type: news

The Kidney Biopsy in Lupus NephritisThe Kidney Biopsy in Lupus Nephritis
Besides the kidney biopsy, which has traditionally been the gold standard for the diagnosis of lupus nephritis, what other options are available to clinicians? Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 23, 2015 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

[Editors' Choice] Normalizing immune cell metabolism treats lupus
Systemic lupus erythematosus is associated with enhanced CD4+ T cell metabolism and can be reversed by metabolic modulators. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 19, 2015 Category: Science Authors: Nancy Gough (mailto:ngough at aaas.org) Source Type: news

Rheumatology Research Highlights - Winter 2015
(Wiley) Rheumatology Research Highlights provides members of the media with important medical evidence that focuses on rheumatic diseases such as rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, juvenile arthritis and fibromyalgia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2015 Category: Global & Universal Source Type: news

Four reasons your autoimmune disorder won't go away
(NaturalNews) Auto-immune disorders are crippling the people of this planet. Whether it's celiac, Graves, Hashimoto's, multiple sclerosis, rheumatoid arthritis, or lupus, these disorders cause considerable pain and destruction of all areas of the body. Although many sufferers have... (Source: NaturalNews.com)
Source: NaturalNews.com - February 14, 2015 Category: Consumer Health News Source Type: news

Peritoneal Dialysis OK for Lupus Patients
(MedPage Today) -- Mortality no worse than in non-lupus ESRD. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - February 13, 2015 Category: Primary Care Source Type: news

Why Lupus Patients Don?t Get Vaccinated (CME/CE)
(MedPage Today) -- A new study indicates healthcare providers may be at fault. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - February 13, 2015 Category: Geriatrics Source Type: news

Long-term Etanercept Safe, Effective in Refractory Lupus (CME/CE)
(MedPage Today) -- More than 80% of patients achieved clinical remission in the open-label study. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 12, 2015 Category: Rheumatology Source Type: news

ESRD Mortality Varies by Race in Lupus (CME/CE)
(MedPage Today) -- Lower in Hispanics, higher in blacks relative to rates in white patients. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 4, 2015 Category: Cardiology Source Type: news

Lupus Doesn't Add to Risk for TKA or THA (CME/CE)
(MedPage Today) -- Replacing knees or hips may reduce pain and improve function for SLE patients. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 3, 2015 Category: Psychiatry Source Type: news

SLE Patients Say Disease Hinders Ability to Work (CME/CE)
(MedPage Today) -- Employability may be enhanced by better lupus treatment. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - February 2, 2015 Category: Primary Care Source Type: news

Suicide attempts in patients with systemic lupus erythematosus: a single-center experience and literature review - Tang KT, Hsieh CW, Hsieh TY, Lan JL, Chen YH, Chen Y.
BACKGROUND: Suicide is a global health issue, and an increase in suicide risk has been found in patients with systemic lupus erythematosus (SLE) when compared with the general population. However, only a few studies have described suicide attempts in patie... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 1, 2015 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news

Renal Biopsy OK in Lupus Pregnancy (CME/CE)
(MedPage Today) -- Histology can help guide important treatment decisions. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 28, 2015 Category: Primary Care Source Type: news

Predicting Renal Disease in Lupus Nephritis Predicting Renal Disease in Lupus Nephritis
Dr Deane reviews the findings of an experiment demonstrating the mechanistic role of vimentin in lupus nephritis and its potential for identifying pharmacologic targets and biomarkers. Medscape Rheumatology (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - January 27, 2015 Category: Urology & Nephrology Tags: Rheumatology Viewpoint Source Type: news

Body Image Intervention to Improve Health Outcomes in LupusBody Image Intervention to Improve Health Outcomes in Lupus
Will a body image intervention improve health outcomes among women with cutaneous SLE? Journal of Clinical Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 26, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

ImmuPharma, Simbec-Orion to execute Phase III trial of Lupuzor to treat Lupus
UK-based companies ImmuPharma and Simbec-Orion Group have entered into a collaboration agreement to execute ImmuPharma’s pivotal Phase III clinical trial of its lead compound Lupuzor to treat Lupus, a chronic, potentially life-threatening autoimmune … (Source: Drug Development Technology)
Source: Drug Development Technology - January 23, 2015 Category: Pharmaceuticals Source Type: news

Look for CMV in Kids With Lupus (CME/CE)
(MedPage Today) -- Persistent fever is a clue to possible cytomegalovirus infection. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 20, 2015 Category: Infectious Diseases Source Type: news

Plaquenil Cuts Diabetes Risk in Lupus (CME/CE)
(MedPage Today) -- The reduced risk was dose-dependent. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 19, 2015 Category: Primary Care Source Type: news

Gut microbes trigger autoimmune disease later in life in mice
The colonization of the gut of young mice by certain types of bacteria can lead to immune responses later in life that are linked to disease, researchers report. Increases in the levels of segmented filamentous bacteria can trigger changes in the lymphoid tissue of the mouse gut that result in the production of antibodies that attack components of the cell nucleus. This type of damage is a hallmark of autoimmune diseases like systemic lupus erythematosus and systemic sclerosis where organs throughout the body are damaged by wayward immune responses. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 19, 2015 Category: Science Source Type: news

Gut microbes trigger autoimmune disease later in life in mice
(EMBO) Researchers have revealed that the colonization of the gut of young mice by certain types of bacteria can lead to immune responses later in life that are linked to disease. Increases in the levels of segmented filamentous bacteria can trigger changes in the lymphoid tissue of the mouse gut that result in the production of antibodies that attack components of the cell nucleus. This type of damage is a hallmark of autoimmune diseases like systemic lupus erythematosus and systemic sclerosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 19, 2015 Category: Global & Universal Source Type: news

Lupus Death Rates Vary by Race, Ethnicity, Study Finds
Asians, Hispanics most likely to survive the autoimmune disease (Source: WebMD Health)
Source: WebMD Health - January 15, 2015 Category: Consumer Health News Source Type: news

Lupus Death Rates Vary by Race, Ethnicity, Study Finds
Asians, Hispanics most likely to survive the autoimmune disease Source: HealthDay Related MedlinePlus Pages: Health Disparities, Lupus (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 15, 2015 Category: Consumer Health News Source Type: news

Lower mortality rates among Asian, Hispanic lupus patients
Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or Native Americans with the disease, scientists have found. Findings indicate that the risk for death among White patients is much lower than in Black and Native American SLE patients. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 15, 2015 Category: Science Source Type: news

Race Matters in Lupus Mortality (CME/CE)
(MedPage Today) -- High death rates seen for blacks and Native Americans. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 15, 2015 Category: Primary Care Source Type: news

Lupus Death Rates Vary by Race, Ethnicity, Study Finds
Title: Lupus Death Rates Vary by Race, Ethnicity, Study FindsCategory: Health NewsCreated: 1/15/2015 12:00:00 AMLast Editorial Review: 1/15/2015 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - January 15, 2015 Category: Rheumatology Source Type: news

Lower mortality rates among Asian and Hispanic lupus patients
(Wiley) A new study by researchers from Brigham and Women's Hospital in Boston, Massachusetts reveals that Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or Native Americans with the disease. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology, indicate that the risk for death among White patients is much lower than in Black and Native American SLE patients. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 15, 2015 Category: Infectious Diseases Source Type: news