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The next generation of prenatal testing: let ’s proceed with caution
Catherine Joynson, from the Nuffield Council on Bioethics, discusses a new prenatal screening test launching in 2018 Related items fromOnMedica Leading the way with NHS Screening Programmes Blood test identifies high-risk lupus pregnancies Maternity care to become more ‘personalised’ New NHS screening for Down's expected soon (Source: OnMedica Views)
Source: OnMedica Views - March 20, 2017 Category: Primary Care Source Type: news

Belimumab for Lupus: Helpful in the Real World (CME/CE)
(MedPage Today) -- More than half had improvement of 50% or more at 6 months (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 18, 2017 Category: Primary Care Source Type: news

Facial erythema: Side effects of anti-fungal drugs - drug rashes
View the full imagePatient AB: Voriconazole rash. Following 8 weeks of Voriconazole, patient had remarkable facial erythema, most consistent with sun exposure because of sparing of her neck.View the full imagePatient AB: Voriconazole rash. Following 8 weeks of Voriconazole, patient had remarkable facial erythema, most consistent with sun exposure because of sparing of her neck.View the full imagePatient AB: Discoid lupus erythematosus following 12 months voriconazole therapy. This improved with use of sunblock factor 30 and resolved after discontinuation of voriconazole, 2 months later.Facial erythema: Side effects of anti...
Source: The Aspergillus Website - updates - March 17, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Modified red blood cells 'could alleviate autoimmune diseases'
This study is interesting and has the potential to be a tool used to both treat and prevent rheumatoid arthritis. It is promising to see that autoimmunity could be treated in mice, but people with arthritis need to be aware that this research is in its very early stages. "More research is needed to determine how the results can be translated into a benefit for people living inpain now, and for those who may develop arthritis in the future." (Source: Arthritis Research UK)
Source: Arthritis Research UK - March 17, 2017 Category: Rheumatology Source Type: news

Selena Gomez Says Therapy Completely Changed Her Life
Can we get an amen for this? Selena Gomez spoke to Vogue about recently taking a break from the spotlight to focus on her psychological well-being. She candidly praised the power of therapy in the interview, saying she sees a mental health professional five days a week. Gomez, who revealed in 2015 she had been diagnosed with lupus, specifically credited Dialectical Behavioral Therapy for helping her manage depression and anxiety. The technique, a form of talk therapy, teaches patients how to “accept” uncomfortable thoughts in order to make it easier to change them. The practice also places an emp...
Source: Healthy Living - The Huffington Post - March 16, 2017 Category: Consumer Health News Source Type: news

Tackling Lupus and its renal complications with novel small molecule drug candidate
A drug starting through the pipeline could ameliorate or even eliminate the symptoms in most lupus sufferers, report researchers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 7, 2017 Category: Science Source Type: news

Infection Rates High in Kids with SLE (CME/CE)
(MedPage Today) -- Highest rates seen in those with lupus nephritis (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 23, 2017 Category: Infectious Diseases Source Type: news

Neanderthal DNA contributes to human gene expression
The last Neanderthal died 40,000 years ago, but much of their genome lives on, in bits and pieces, through modern humans. The impact of Neanderthals'genetic contribution has been uncertain. Researchers now report evidence that Neanderthal DNA sequences still influence how genes are turned on or off in modern humans. Neanderthal genes'effects on gene expression likely contribute to traits such as height and susceptibility to schizophrenia or lupus, the researchers found. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 23, 2017 Category: Science Source Type: news

Neovacs and BioSense partner to develop and commercialise IFNa Kinoid in China
French-based Neovacs has signed a commercial licence option agreement with BioSense Global for the development and commercial rights of IFN α Kinoid vaccine to treat lupus and dermatomyositis in China. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - February 22, 2017 Category: Pharmaceuticals Source Type: news

Infections in Lupus: Do Meds Contribute? (CME/CE)
(MedPage Today) -- Steroids and immunosuppressants risky; antimalarials benefit (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 14, 2017 Category: Infectious Diseases Source Type: news

Systemic Lupus Erythematosus Quiz: Test Your SLE IQ
Title: Systemic Lupus Erythematosus Quiz: Test Your SLE IQCategory: MedicineNet QuizCreated: 8/17/2011 1:33:00 PMLast Editorial Review: 2/13/2017 3:45:54 PM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 13, 2017 Category: Rheumatology Source Type: news

Stressed out interferons reveal potential key to alternative lupus treatment
New research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target for treating the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 10, 2017 Category: Science Source Type: news

Stressed out interferons reveal potential key to alternative lupus treatment
(University of Vermont) New research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target for treating the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 10, 2017 Category: Global & Universal Source Type: news

Study of complex genetic region finds hidden role of NCF1 in multiple autoimmune diseases
(Medical University of South Carolina) Medical University of South Carolina investigators report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sj ö gren's syndrome, in the January 2017 issue of Nature Genetics. Data indicate that increased NCF1 protects against SLE while decreased NCF1 raises SLE risk and highlight the pathogenic role of reduced reactive oxygen species in autoimmune disease development. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 8, 2017 Category: Biology Source Type: news

Lupus in Kids: Damage Starts Early (CME/CE)
(MedPage Today) -- Antimalarials helped protect against organ damage (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - February 5, 2017 Category: Pediatrics Source Type: news

Lupus: A Continuum of Disease? (CME/CE)
(MedPage Today) -- Incomplete lupus is often mild, but can progress, cause damage (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 31, 2017 Category: Primary Care Source Type: news

A wolf's stowaways
Since the year 2000, the Eurasian grey wolf, Canis lupus lupus, has spread across Germany. For researchers, a good reason to have a closer look at the small “occupants” of this returnee and to ask the question whether the number and species of parasites change with an increasing wolf population. This was the case, because the number of parasite species per individual wolf increased as the wolf population expanded. Furthermore, cubs had a higher dive rsity of parasite species than older animals. The good news: wolf parasites do not pose a threat to human health. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 27, 2017 Category: Science Source Type: news

Lupus in Hispanic Communities: Challenges and Resources to Support Early Diagnosis and Improved Quality of Care
January 27, 2017 1-1:45pm ET. (Source: HSR Information Central)
Source: HSR Information Central - January 26, 2017 Category: Global & Universal Source Type: news

Lupus: Pain in Neck & Back
Title: Lupus: Pain in Neck& BackCategory: Doctor's& Expert's views on SymptomsCreated: 8/29/2000 12:00:00 AMLast Editorial Review: 1/26/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - January 26, 2017 Category: Rheumatology Source Type: news

Lupus Patients Less Inclined to Stick with Meds (CME/CE)
(MedPage Today) -- More than half reported non-adherence (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 25, 2017 Category: Primary Care Source Type: news

What is in the Differential Diagnosis of Fatigue?
Discussion Fatigue is a subjective feeling of decreased energy, tiredness or feeling of exhaustion. Lethargy is often used synonymously, but lethargy is a state of being drowsiness or sleepy, and implies mental status changes. Both can cause the person to be apathetic or less active. Fatigue is a common state that almost everyone experiences multiple times in his or her lifetime. For most people it is a relatively acute or short-term chronic problem, often with a relatively easily identifiable problem cause, such as inadequate sleep, acute illness, or overexertion. For some, it can be less readily identifiable such as dep...
Source: PediatricEducation.org - January 23, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Jokiva Rivers suffers from genetic condition that causes severe blisters
Jokiva Rivers, from New Orleans, started to notice blisters forming across her cheeks and necks when she was 18 - but her doctors were unsure why. But medical tests revealed she had lupus. (Source: the Mail online | Health)
Source: the Mail online | Health - January 13, 2017 Category: Consumer Health News Source Type: news

Lupus Nephritis Treatment
Title: Lupus Nephritis TreatmentCategory: Doctor's& Expert's views on SymptomsCreated: 3/1/2002 12:00:00 AMLast Editorial Review: 1/12/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - January 12, 2017 Category: Rheumatology Source Type: news

Off-Label Use of Rituximab for SLE in Europe Off-Label Use of Rituximab for SLE in Europe
Is rituximab, used on an off-label basis to treat SLE, a safe and effective alternative to conventional therapy?Lupus Science & Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 6, 2017 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

'Miracle Baby' Who Weighed Less Than 1 Pound At Birth Is Now A Thriving Teen
Eric and Tammy Koz always wanted to be parents. So when the young couple found out they were pregnant with a little girl in 2003 after a devastating miscarriage, they were beyond thrilled. “I was ecstatic,” Tammy told “The Oprah Show” in 2004. “I had a very positive outlook on the pregnancy. I think I’m probably the only one that did...” The reason many were fearful, Tammy explained back then, was due to her having lupus, an autoimmune disease that increased her risk of miscarriage. Yet, this particular pregnancy was going smoothly ― until 19 weeks, when a routine ultrasound reve...
Source: Healthy Living - The Huffington Post - January 5, 2017 Category: Consumer Health News Source Type: news

Carrie Fisher's Death Highlights The Reality Of Heart Disease In Women
Carrie Fisher died early Tuesday morning, four days after suffering a heart attack on a flight from London to Los Angeles. The actress and author, best known for her iconic role as Princess Leia in the “Star Wars” franchise, was 60 years old.  Experts say that Fisher’s death highlights an important reality about heart disease: It is the leading cause of death among men and women alike in the U.S. While heart disease encompasses many different conditions, a heart attack occurs when coronary arteries become blocked and oxygenated blood can’t reach the heart. About 735,000 Americans have hea...
Source: Science - The Huffington Post - December 28, 2016 Category: Science Source Type: news

Carrie Fisher's Death Highlights The Reality Of Heart Disease In Women
Carrie Fisher died early Tuesday morning, four days after suffering a heart attack on a flight from London to Los Angeles. The actress and author, best known for her iconic role as Princess Leia in the “Star Wars” franchise, was 60 years old.  Experts say that Fisher’s death highlights an important reality about heart disease: It is the leading cause of death among men and women alike in the U.S. While heart disease encompasses many different conditions, a heart attack occurs when coronary arteries become blocked and oxygenated blood can’t reach the heart. About 735,000 Americans have hea...
Source: Healthy Living - The Huffington Post - December 28, 2016 Category: Consumer Health News Source Type: news

The Secret To Treating Autoimmune Disease May Lie In The Gut
An estimated 50 million Americans ― that’s 20 percent of the general population ― suffer from autoimmune diseases like lupus, multiple sclerosis or rheumatoid arthritis, and many experts say that number is rising at an alarming rate.  Autoimmunity occurs when the immune system begins attacking the body’s healthy tissue as if it were an outside invader, leading to chronic inflammation. We still don’t know much about what causes the immune system to go haywire, or how to effectively treat it. But new research suggests that the gut microbiome ― the community of trillions of “g...
Source: Science - The Huffington Post - December 21, 2016 Category: Science Source Type: news

The Secret To Treating Autoimmune Disease May Lie In The Gut
An estimated 50 million Americans ― that’s 20 percent of the general population ― suffer from autoimmune diseases like lupus, multiple sclerosis or rheumatoid arthritis, and many experts say that number is rising at an alarming rate.  Autoimmunity occurs when the immune system begins attacking the body’s healthy tissue as if it were an outside invader, leading to chronic inflammation. We still don’t know much about what causes the immune system to go haywire, or how to effectively treat it. But new research suggests that the gut microbiome ― the community of trillions of “g...
Source: Healthy Living - The Huffington Post - December 21, 2016 Category: Consumer Health News Source Type: news

Markers That Predict SLE Found in At-Risk Relatives Markers That Predict SLE Found in At-Risk Relatives
Biomarkers and clinical features identified high-risk relatives of patients with lupus who might be candidates for early treatment.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 20, 2016 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news

Scientists use biomarkers to track lupus progression
Amy WallaceANN ARBOR, Mich., Dec. 16 (UPI) -- A team from the University of Michigan are examining whether kidney biomarkers can track the beginnings and progression of lupus. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 16, 2016 Category: Consumer Health News Source Type: news

Investigating kidney biomarkers to track lupus
(University of Michigan Health System) To try to better understand how the disease begins and progresses, researchers at the University of Michigan investigated whether kidney biomarkers would signal lupus progression and signs of complications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 16, 2016 Category: Global & Universal Source Type: news

MRI scan provides more certainty in diagnosing foetal abnormalities
Researchers propose MRI scan be offered when foetus has a suspected brain abnormality Related items fromOnMedica Blood test identifies high-risk lupus pregnancies Experts find ‘substantial’ variation in maternity care ‘Red flag’ unwell pregnant women to curb maternal deaths, clinicians told ‘Morning sickness’ linked to lower risk of pregnancy loss New guidelines on epilepsy in pregnancy (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 14, 2016 Category: UK Health Source Type: news

Video: Translating science into new medicines
Researchers and scientists at America ’s biopharmaceutical companies and around the globe work every day to translate science into new treatments and cures to allow patients to live longer, healthier lives. This work is particularly important to people facing illnesses that have historically had limited treatment options, like cancer, lupus and multiple sclerosis (MS).Fortunately for these patients in need, the pipeline of new, innovative medicines has never been more promising, and advances in recent decades have brought a number of therapies to people battling a disease or managing a chronic condition that have hel...
Source: The Catalyst - December 12, 2016 Category: Pharmaceuticals Tags: cancer member companies Drug Development Multiple Sclerosis Source Type: news

Neovacs obtains FDA “Fast Track” designation for IFNand#945; Kinoid in Lupus (SLE)
PARIS and BOSTON, Dec. 07, 2016 -- (Healthcare Sales & Marketing Network) -- Neovacs (Alternext Paris:ALNEV), a leader in active immunotherapies for the treatment of autoimmune diseases, today announced that the U.S. Food and Drug Administration (FDA) has ... Biopharmaceuticals, FDA Neovacs, IFNα Kinoid, autoimmune disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 7, 2016 Category: Pharmaceuticals Source Type: news

Molecular Signatures in Systemic Lupus Erythematosus Molecular Signatures in Systemic Lupus Erythematosus
An improved understanding of the molecular signatures in SLE can help better distinguish between flare and infection.Lupus Science & Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Immune cells 'play a role in increasing heart disease risk for people with lupus'
This study shows that it may be possible to predict the progression and severity of atherosclerosis in lupus, which could play a vital role in the prevention and treatment of the condition. This new insight will help us in planning the right services for people with lupus who are at a greater risk of heart disease, so that they can be closely monitored and supported by their healthcare professionals, ensuring prompt and effective treatment." (Source: Arthritis Research UK)
Source: Arthritis Research UK - December 7, 2016 Category: Rheumatology Source Type: news

Medical News Today: What Is My Life Expectancy If I Have Lupus?
How long can people with lupus expect to live? Learn how lupus can affect different parts of the body and what steps people may take to live with lupus. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 2, 2016 Category: Consumer Health News Tags: Lupus Source Type: news

[This Week in Science] Overactive antiviral responses in lupus
Author: John F. Foley (Source: ScienceNOW)
Source: ScienceNOW - December 1, 2016 Category: Science Authors: John F. Foley Tags: Oxidative Stress Source Type: news

A Review of Systemic Lupus Erythematosus A Review of Systemic Lupus Erythematosus
Review the clinical features of SLE and the wide variety of medications and non-pharmacologic therapies which are used to target its symptoms in this primer.U.S. Pharmacist (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 29, 2016 Category: Intensive Care Tags: Rheumatology Journal Article Source Type: news

Big ideas and little changes – our CEO shares renewed ambition to change lives today and tomorrow
A future free from arthritis and the impact of arthritis has been the driving force behind Arthritis Research UK since we first began 80 years ago.In 2016 we remain focussed on the future, continuing our multi-million-pound investment in exceptional science, but we’re also evolving to ensure we meet the needs of people with arthritis right now and transform lives today.We asked our Chief Executive Officer Dr Liam O’Toole to share with you how we’re broadening our scope and ambitions and, most importantly, how these little changes to our approach will help everybody live fuller lives with arthritis today a...
Source: Arthritis Research UK - November 25, 2016 Category: Rheumatology Source Type: news

[Research Article] Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus
Oxidative stress oligomerizes an outer mitochondrial membrane protein to trigger an antiviral response in the absence of infection. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - November 22, 2016 Category: Science Authors: Iwona A. Buskiewicz, Theresa Montgomery, Elizabeth C. Yasewicz, Sally A. Huber, Michael P. Murphy, Richard C. Hartley, Ryan Kelly, Mary K. Crow, Andras Perl, Ralph C. Budd, Andreas Koenig Source Type: news

Novel Agent Showing Promise, a First in Lupus Nephritis Novel Agent Showing Promise, a First in Lupus Nephritis
An induction regimen that includes a calcineurin inhibitor can help patients with acute lupus nephritis achieve complete or partial remission, early research suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 21, 2016 Category: Consumer Health News Tags: Nephrology News Source Type: news

Delays in Lupus Care Seen Among Minorities, Less Educated
Title: Delays in Lupus Care Seen Among Minorities, Less EducatedCategory: Health NewsCreated: 11/18/2016 12:00:00 AMLast Editorial Review: 11/21/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 21, 2016 Category: Rheumatology Source Type: news

Lupus Low Disease Activity State Useful Target (CME/CE)
(MedPage Today) -- Large study shows LLDAS achieved by many patients (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 21, 2016 Category: Rheumatology Source Type: news

Researchers Suggest Caution in Treating Lupus Patients With Early, Higher-Dose Prednisone
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - November 19, 2016 Category: Orthopaedics Tags: Trends and Innovations Source Type: news

Lupus care delayed among minorities, less educated
HealthDay News Delays in lupus treatment are more common among Americans who are black, Asian or are less educated, a new study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 18, 2016 Category: Consumer Health News Source Type: news

Delays in Lupus Care Seen Among Minorities, Less Educated
FRIDAY, Nov. 18, 2016 -- Delays in lupus treatment are more common among Americans who are black, Asian or are less educated, a new study finds. Lupus is a chronic autoimmune disease in which inflammation affects the skin, joints, kidneys and other... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 18, 2016 Category: Journals (General) Source Type: news

Investigating the function of play bows in adult pet dogs (Canis lupus familiaris) - Byosiere SE, Espinosa J, Smuts B.
Play bows are a common, highly stereotyped canine behavior widely considered to be a 'play signal,' but only one study has researched their function. Bekoff (1995) found that play bows function as behavioral modifiers to help clarify playful intent before ... (Source: SafetyLit)
Source: SafetyLit - November 16, 2016 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: news

Mallinckrodt begins enrolment for Phase IV study of HP Acthar Gel to treat SLE
Irish biopharmaceutical company Mallinckrodt has begun enrolment for its Phase IV clinical study of HP Acthar Gel to treat systemic lupus erythematosus (SLE) patients with persistently active disease. (Source: Drug Development Technology)
Source: Drug Development Technology - November 16, 2016 Category: Pharmaceuticals Source Type: news