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Jamesetta Smith - Older Americans
When I think of preventive care, I think of a person who enjoys life, however, when I think of acute care, I am reminded of a person who really does not care, a person who has no concerns of ever being sick. Many have the rationale that we all have to die with something. This is saying to me; do I choose, life, death, pain, suffering, surgery, therapy? There is no question for me; I choose LIFE. My imagination would run away with me if I had not followed the steps which I did when I had symptoms which made me feel as if I was losing my mind and thinking death was my only alternative. The experiences I had 5 years prior to ...
Source: PHRMA - June 18, 2014 Category: Pharmaceuticals Authors: Sabrina Source Type: news

Jamesetta Smith
PresidentI was born in Chicago, Illinois and raised in Indiana. I graduated from Oxford Business College in Chicago, Illinois. My marriage of 52 years produced 2 sons. Diagnosed with Systemic Lupus Erythematosus February 1986 at Mayo Clinic was a frightening experience for me which lead me to join a Lupus Support Group in Indiana. The Lupus Foundation of America, Inc. requested that I start a lupus support group in Arkansas after we moved to Hot Springs, Arkansas. This support group was started October 1993 and May 1995, we became a chapter. The support group in Indiana gave me my life back and I wanted to do the same for ...
Source: PHRMA - June 18, 2014 Category: Pharmaceuticals Authors: Sabrina Source Type: news

Dorothy Leone-Glasser
President and CEODorothy Leone-Glasser, RPN, HHC, has lived with systemic lupus for over thirty-five years. As a result, she has overcome two forms of cancer, disabling arthritis, kidney failure, a coma, heart attack, and two strokes. During this time she graduated from a wheelchair to crutches to ultimately walking with her own two feet. Between the ages of 20 and 37, Dorothy received three death sentences imposed by her doctors. Today she is not only alive, but she is living well and paving the way to the future of wellness as President and CEO of the Advocates for Responsible Care (ARxC), a non-profit wellness and advoc...
Source: PHRMA - June 18, 2014 Category: Pharmaceuticals Authors: Sabrina Source Type: news

Genetics Home Reference: systemic lupus erythematosus
http://ghr.nlm.nih.gov/condition/systemic-lupus-erythematosus (Source: NLM General Announcements)
Source: NLM General Announcements - June 17, 2014 Category: Databases & Libraries Source Type: news

In the quest for safer treatment for systemic lupus erythematosus
(University of the Basque Country ) Researchers at the UPV/EHU-University of the Basque Country study what the best treatment is to minimise the side effects of glucocorticoids (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2014 Category: Global & Universal Source Type: news

Pregnancy Possible in Lupus Patients Taking BelimumabPregnancy Possible in Lupus Patients Taking Belimumab
Successful live births are possible in women with lupus who conceive while taking belimumab, new research shows. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 16, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Stopping Immunotherapy Possible in Some Patients With LupusStopping Immunotherapy Possible in Some Patients With Lupus
Some patients with systemic lupus erythematosus who are in clinical remission with immunosuppressant therapy may be able to stop therapy without triggering a new disease flare. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 15, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Invisible Illness: It’s not easy to combat what you can’t see!
There is a surprising common factor which is shared by a vast range of physical and mental health conditions. Fibromyalgia, anxiety, endometriosis, lupus, endometriosis, pelvic pain and depression may vary in causes and symptoms, but all of them have a deadly weapon in common – invisibility. They are often classed as an invisible illness. These conditions fight their invisible war on two fronts. Firstly, they leave no trace. The majority of these diseases attack the body internally, leaving no external signs which might allow the patient’s suffering to be easily recognised. As well as causing physical pain, inv...
Source: The Hysterectomy Association - June 13, 2014 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health Conditions anxiety autoimmune disease depression endometriosis fibromyalgia invisible illness lupus pelvic pain Source Type: news

Pulmonary Manifestations of Systemic Lupus ErythematosusPulmonary Manifestations of Systemic Lupus Erythematosus
Learn more about the clinical presentation, pathogenesis, pathology, management, and prognosis of these SLE-associated lung conditions. Seminars in Respiratory and Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2014 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Anti-dsDNA, surface-expressed TLR4 and endosomal TLR9 cooperate to exacerbate lupus
(Society for Experimental Biology and Medicine) The study by Lee et al. reveals that risk factors, pathogenic anti-dsDNA and combined activation of extracellular and intracellular TLRs, induce SLE syndromes in normal mice. Hence, ongoing studies will determine whether block anti-dsDNA, TLR4 and TLR9 can ameliorate lupus syndrome in lupus mice. Identification of molecular mechanisms contributing to lupus development by co-activation of surface-expressed TLR4 and endo-lysosomal of TLR9 will open new avenues for modulating immune tolerance and suppressing disease progression. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 12, 2014 Category: Global & Universal Source Type: news

New guidance on how and when to stop immunosuppressants in lupus patients
(European League Against Rheumatism) A new study presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) showed that, for the majority of lupus patients who are in remission, it is possible to successfully stop immunosuppressant therapy without triggering a flare of their disease. Within two years, it was possible to stop the immunosuppressant in about 70 percent of clinically stable patients. Half were successful within three years, and this proportion remained stable for up to five years. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 11, 2014 Category: Global & Universal Source Type: news

International Team Creates Heart Disease Risk Tool Tailored to Rheumatoid Arthritis Patients
Method may shed light on how to better gauge heart health in lupus, other inflammatory diseases Rochester, Minn. — Rheumatoid arthritis patients overall are twice as likely as the average person to develop heart problems. Pinpointing which rheumatoid arthritis patients need stepped-up heart disease prevention efforts has been a challenge; research by Mayo Clinic and [...] (Source: Mayo Clinic Rochester News)
Source: Mayo Clinic Rochester News - June 11, 2014 Category: Hospital Management Source Type: news

RheumShorts: Turmeric, Kids' Vasculitis, Autoantibodies (CME/CE)
(MedPage Today) -- This week in rheumatology researchers from around the world reported on the use of curcuminoids for osteoarthritis, autoantibody monitoring for drug-induced lupus, and a rare vasculitis in children. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - May 30, 2014 Category: Geriatrics Source Type: news

Director's Comments: NIH MedlinePlus Magazine Spring 2014
Listen to the NLM Director's Comments on "NIH MedlinePlus Magazine Spring 2014". The transcript is also available. The new edition of NIH MedlinePlus Magazine Spring 2014 covers rethinking drinking, attention deficit hyperactivity disorder, as well as information about lupus.... (Source: What's New on MedlinePlus)
Source: What's New on MedlinePlus - May 28, 2014 Category: Consumer Health News Source Type: news

No Link Seen Between Vaccines and Lupus
(MedPage Today) -- Recent vaccination was not associated with an increased risk for the development of systemic lupus erythematosus (SLE), a case-control study found. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 28, 2014 Category: Primary Care Source Type: news

IgG Stable With Rituxan in Autoimmune Disease
(MedPage Today) -- Repeated doses of rituximab in patients with vasculitis or lupus had no association with increased rates of low immunoglobulin (Ig)G, an important infection-fighting component of the immune system, a retrospective study found. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - May 28, 2014 Category: Infectious Diseases Source Type: news

Lupus Therapies Continue to Evolve
May is National Lupus Awareness Month, a time to think about lupus and the challenges it presents to patients. Learn about this chronic, autoimmune disease and the promise of future therapies. (Source: FDA Consumer Updates)
Source: FDA Consumer Updates - May 27, 2014 Category: Consumer Health News Source Type: news

Salad Bars Vanish From Boston Schools
BOSTON (CBS) – Teaching kids about good nutrition is a life lesson, but in Boston Public Schools salad bars have vanished. The move is leaving a sour taste for many parents, as well as the mayor. With First Lady Michelle Obama pushing healthy foods in school, half a dozen Boston schools were among those who bought into lunchroom salad bars in the battle against childhood obesity. A couple years later, none remain – to the chagrin of parents hoping to pry their kids away from junk food. “My little one’s not in school yet, but I’d hope by the time he gets there that they’d have healthy opt...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 27, 2014 Category: Consumer Health News Authors: Julie Eich Tags: Education Health Local News Syndicated Local Boston Public Schools Childhood Obesity Healthy Eating mayor marty walsh Salad Bar Source Type: news

Make the diagnosis, Sherlock!
This is a case recently reported in the Medical Journal of Australia.  A 50-year-old woman presented with a read, painful, scaling rash on her hand an forearms, and around her eyes. She reported that sun exposure aggravated the dermal symptoms. She also gave a history of intermittent diarrhea. Examination revealed a scaly hyperpigmented lesion on her upper chest, in the distribution of a broad collar. The patient was a smoker and said she consumed half a bottle of gin daily. The skin manifestations did not respond to antibiotics or steroids. Click on the following questions to reveal the answers. Was is the diagn...
Source: The Poison Review - May 22, 2014 Category: Toxicology Authors: Leon Tags: Medical dermatitis niacin deficiency pellagra Source Type: news

AR CAG repeat and autoimmunity in lupus
Clinical and experimental evidence support a role for gonadal steroids in modulating the expression and course of autoimmune diseases such as lupus. It is not known if inherited variation in sensitivity to circulating androgenic hormones could influence the manifestations of such a disease. Olsen and colleagues found that shorter AR CAG repeat lengths in lupus subjects correlated with a higher Systemic Lupus Erythematosus Disease Activity Index score, higher ANA levels, expression of a broader array of IgG autoantibodies, more severe clinical manifestations, and more exuberant humoral autoimmunity. These findings suggest a...
Source: Society for Endocrinology - May 21, 2014 Category: Endocrinology Source Type: news

What Causes Leg Pain?
Discussion “Growing pains” of the legs are a common complaint in children. Heterogeneous studies from 1928-2004 have found prevalence rates of 2.6-49.4% in children ages 4-19. The studies are heterogeneous because of time, location, and especially definition of growing pains. A study of 1445, 4-6 year olds in 2004 using a validated tool showed a prevalence rate of 36.9%. The definition of growing pains used by Peterson in the 2004 study is chronic “…intermittent (nonarticular) pains in both legs that generally occur late in the day or at night…” with a normal physical examination and ...
Source: PediatricEducation.org - May 19, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Blisibimod Shows Some Promise for Moderate to Severe SLEBlisibimod Shows Some Promise for Moderate to Severe SLE
Blisibimod, an inhibitor of B cell-activating factor (BAFF), improves some endpoints in patients with systemic lupus erythematosus, especially those with more severe disease, according to results from the phase 2 PEARL-SC study. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 16, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Treating Lupus: Mayo Clinic Radio Health Minute
In this Mayo Clinic Radio Health Minute, Dr. Vaidehi Chowdhary discusses treatment options for lupus. To listen, click the link below. Treating Lupus (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 16, 2014 Category: Databases & Libraries Source Type: news

RheumShorts: New Knees, Lupus Med Switches (CME/CE)
(MedPage Today) -- The news in rheumatology this week included reports on knee replacements in the Dominican Republic, outcomes with scleroderma overlap disease, and reasons for switching maintenance therapy in lupus. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - May 15, 2014 Category: Geriatrics Source Type: news

B cells produce antibodies 'when danger calls, but not when it whispers,' scientists report
The immune system’s B cells protect us from disease by producing antibodies, or "smart bullets," that specifically target invaders such as pathogens and viruses while leaving harmless molecules alone. But how do B cells determine whether a threat is real and whether to start producing these weapons? An international team of life scientists shows in the May 16 issue of the journal Science how and why these cells respond only to true threats. "It is critical for B cells to respond either fully or not at all. Anything in between causes disease," said the study’s senior author, Alexander Hoffma...
Source: UCLA Newsroom: Health Sciences - May 15, 2014 Category: Universities & Medical Training Source Type: news

Heart failure hospitalisation more than doubles in IBD flares
Dr Søren L. Kristensen, lead author, said: “Previous studies have shown an association between chronic inflammatory diseases (psoriasis, rheumatoid arthritis, systemic lupus erythematosus, celiac disease and IBD) and an increased incidence of venous- and arterial thrombotic disease (primarily heart attack and stroke). Researchers suggest the link is at least in part caused by inflammatory prothrombotic effects.” Topics: Heart Failure (HF) (Source: ESC News and Press)
Source: ESC News and Press - May 14, 2014 Category: Cardiology Source Type: news

Shingle Risk High in Lupus, RA, COPD
(MedPage Today) -- Patients with autoimmune diseases and certain other chronic conditions are at increased risk for herpes zoster, a U.K. case-control study found. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - May 14, 2014 Category: Geriatrics Source Type: news

Lupus Studies Point to Gut Microbes, EpigeneticsLupus Studies Point to Gut Microbes, Epigenetics
Intestinal 'microbiome' and epigenetic changes in gene expression might contribute to systemic lupus erythematosus and could offer new routes to therapy, new studies have suggested. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 13, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Dear Lupus, I want me back
My name is Lauren Johnson. I'm an associate producer at CNN, and I have systemic lupus erythematosus. (Source: CNN.com - Health)
Source: CNN.com - Health - May 12, 2014 Category: Consumer Health News Source Type: news

Arthritis, lupus and asthma data a shot in arm for AstraZeneca
AstraZeneca received a filli as 4 experimental drugs for rheumatoid arthritis, lupus and asthma showed promising results in mid-stage clinical trials. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 12, 2014 Category: Pharmaceuticals Source Type: news

Arthritis, lupus and asthma data a shot in arm for AstraZeneca
LONDON (Reuters) - AstraZeneca, fighting a $106 billion bid approach from Pfizer, received a fillip on Monday as four experimental drugs for rheumatoid arthritis, lupus and asthma showed promising results in mid-stage clinical trials. (Source: Reuters: Health)
Source: Reuters: Health - May 12, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Rheuminations: Drug-Induced Lupus, a Case Report
LIVERPOOL (MedPage Today) -- Despite more than 15 years of experience with biologic therapies in rheumatology, unwelcome surprises can still happen, as was shown in this case report. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 9, 2014 Category: Primary Care Source Type: news

Low Vitamin D Worsens Lupus Risks in Kids (CME/CE)
(MedPage Today) -- Children with lupus commonly are vitamin D deficient, which may contribute to their heightened inflammatory status and cardiovascular risk, researchers reported. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - May 8, 2014 Category: Pediatrics Source Type: news

Lupus (Systemic Lupus Erythematosus)
Title: Lupus (Systemic Lupus Erythematosus)Category: Diseases and ConditionsCreated: 8/20/2013 2:45:00 PMLast Editorial Review: 5/8/2014 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - May 8, 2014 Category: Rheumatology Source Type: news

Global Market for Drugs to Treat SLE to Reach $2.6 Billion In 2018;...
According to a new report from BCC Research, the global market for drugs to treat systemic lupus erythematosus (SLE), is expected to grow to $2.6 billion by 2018, with a five-year compound annual...(PRWeb April 28, 2014)Read the full story at http://www.prweb.com/releases/2014/04/prweb11801657.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - April 29, 2014 Category: Pharmaceuticals Source Type: news

How To Reverse Lupus Now Review | How To Get Rid Of Lupus With Matt...
How To Reverse Lupus Now, written by Matt Traverso, is a new program that teaches people how to get rid of lupus efficiently. The review of How To Reverse Lupus Now on the site HealthReviewCenter.com...(PRWeb April 26, 2014)Read the full story at http://www.prweb.com/releases/reverse-lupus-now/review/prweb11799949.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - April 27, 2014 Category: Pharmaceuticals Source Type: news

Pregnancy Risks Higher for Blacks With Lupus
(MedPage Today) -- African-American women with lupus are at increased risk for adverse pregnancy outcomes, even before they are diagnosed with the disease, a retrospective study found. (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 26, 2014 Category: OBGYN Source Type: news

B-Cell Targeting Has Benefit in Severe Lupus (CME/CE)
(MedPage Today) -- Although an inhibitor of B-cell activating factor failed to meet the primary endpoint in a phase II trial for lupus, beneficial effects were seen in patients with severe disease at baseline, researchers reported. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 24, 2014 Category: Primary Care Source Type: news

DC Residents Led by Nick Cannon in Walk to End Lupus Now
More than 4,000 people with lupus, their friends and families converged in the nation's capital on Saturday to shed light on the cruel mystery that is lupus. Grand marshaled by multi-talented entertainer and television personality Nick Cannon, the Lupus Foundation of America's Walk to End Lupus Now™ event in Washington, D.C. transformed Pennsylvania Avenue into a stream of purple, the color lupus advocates associate with this debilitating, poorly understood disease. (Source: Disabled World)
Source: Disabled World - April 20, 2014 Category: Disability Tags: Lupus Source Type: news

Treat-to-Target the New Goal in Lupus
(MedPage Today) -- An international task force has taken the first steps toward formulating a "treat to target" approach for the treatment of systemic lupus erythematosus (SLE), focusing on remission, damage prevention, and quality of life. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 18, 2014 Category: Primary Care Source Type: news

10 Common Mistakes in the Management of Lupus Nephritis10 Common Mistakes in the Management of Lupus Nephritis
Are the most common ways to treat lupus nephritis necessarily the most effective and the safest? This new study takes a look. American Journal of Kidney Diseases (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - April 18, 2014 Category: Urology & Nephrology Tags: Nephrology Journal Article Source Type: news

Smoking Tied to Worse Lupus, Arthritis (CME/CE)
(MedPage Today) -- Worse patterns of disease for both rheumatoid arthritis and systemic lupus erythematosus were seen among patients who were smokers, and the risks actually increased after quitting for those with lupus, Swedish researchers reported. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - April 13, 2014 Category: Geriatrics Source Type: news

Stem Cells Seen as Promising in Lupus (CME/CE)
(MedPage Today) -- Mesenchymal stem cell transplantation is showing promise as a treatment for refractory systemic lupus erythematosus, researchers have reported. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 11, 2014 Category: Primary Care Source Type: news

In Vivo Cell Transfer Assay to Detect Autoreactive T Cell Subsets
Among the methods used in molecular biology, in vitro biochemical assays are more common, whereas in vivo assays, including the use of animal models, are less widely employed. In our studies on systemic lupus erythematosus (SLE), we have identified a novel T cell subtype termed “autoantibody-inducing CD4 T cells” (aiCD4 T cell) that is responsible for the development of autoimmunity. In order to identify and isolate these cells, we developed a new technique that involves the transfer of candidate T cell subpopulations into naïve mice and assaying for the development of autoantibodies in the recipient mice....
Source: Springer protocols feed by Molecular Medicine - April 7, 2014 Category: Molecular Biology Source Type: news

Induction of De Novo Autoimmune Disease in Normal Mice upon Repeated Immunization with Antigen
We describe here a novel and completely reproducible experimental technique that can induce systemic autoimmunity or systemic lupus erythematosus (SLE) in mice otherwise not prone to spontaneous autoimmune disease. This protocol involves the repeated immunization of mice with the same antigen. This rather simple technique enables us to perform exact and quantitative in vivo animal experiments with great accuracy. (Source: Springer protocols feed by Molecular Medicine)
Source: Springer protocols feed by Molecular Medicine - April 7, 2014 Category: Molecular Biology Source Type: news

What is Lupus: Mayo Clinic Radio Health Minute
In this Mayo Clinic Radio Health Minute, Dr. Vaidehi Chowdhary explain lupus. To listen, click the link below. What is Lupus   (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 2, 2014 Category: Databases & Libraries Source Type: news

Shingles Vaccine OK in Mild Lupus
NEW YORK (MedPage Today) -- Vaccination against shingles may be safe for patients with mild, stable systemic lupus erythematosus, a researcher said here. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - March 24, 2014 Category: Geriatrics Source Type: news

Primary Cardiac Disease Still Occurs in Lupus
(MedPage Today) -- Pericarditis and other forms of primary cardiac disease can occur at any time during the course of systemic lupus erythematosus, but antimalarial treatment can be protective, South American researchers reported. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 19, 2014 Category: Primary Care Source Type: news

Discounted Systemic Lupus Erythematosus and Lupus Nephritis Treatment...
Discounted research study “PharmaPoint: Systemic Lupus Erythematosus and Lupus Nephritis - Global Drug Forecast and Market Analysis to 2022” elaborated by GlobalData is now available at...(PRWeb March 18, 2014)Read the full story at http://www.prweb.com/releases/2014/03/prweb11679578.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 18, 2014 Category: Pharmaceuticals Source Type: news

Class, ancestry and medication are factors in cardiac risk for lupus patients
New research published in Rheumatology, the international, peer-reviewed scientific journal, has suggested that systemic lupus erythematosus (SLE) patients of African descent and from lower socioeconomic groups face a higher risk of primary cardiac disease. However, those taking anti-malarial drugs reduce their risk.The research found that 14% of patients experience cardiac problems as a result of the auto-immune disorder within five years of diagnosis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 18, 2014 Category: Consumer Health News Tags: Lupus Source Type: news