Initiative aims to improve transition from pediatric to adult care
Gregg Michael Talente, MD, remembers well a young patient who nearly fell through the gap between pediatric an adult health care. The woman was treated for lupus by her pediatrician until age 19... (Source: Family Practice News)
Source: Family Practice News - June 30, 2016 Category: Primary Care Source Type: news

2016 Lupus Insight Prize presented to Dr. Ann Marshak-Rothstein
(Lupus Research Institute) The 2016 Lupus Insight Prize was awarded to Ann Marshak-Rothstein, Ph.D., University of Massachusetts Medical School, for a project with great promise to improve the treatment of lupus-related skin disease. Announced at FOCIS 2016, the 16th Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS), the $200,000 Lupus Insight Prize is a collaborative initiative among the Alliance for Lupus Research (ALR), the Lupus Foundation of America and the Lupus Research Institute (LRI). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2016 Category: Global & Universal Source Type: news

CV Risk in Lupus Patients Grows (CME/CE)
(MedPage Today) -- Not sharing in decline seen in general population (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 27, 2016 Category: Rheumatology Source Type: news

Researchers discover potential genetic trigger of autoimmune disease
Researchers have uncovered a potential genetic trigger of systemic autoimmune disease. The study discovered virus-like elements within the human genome linked to the development of two autoimmune diseases: lupus and Sjogren's syndrome. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 27, 2016 Category: Science Source Type: news

Severe Asthma Symptoms Persist After Decade of Treatment: ConsultantLive & Rheumatology Network
(MedPage Today) -- Also, lupus linked to dementia risk? (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - June 21, 2016 Category: Allergy & Immunology Source Type: news

African-American lupus patient immune cell characteristics may increase disease severity
(JCI Journals) In this issue of JCI Insight, Laurence Menard and colleagues at Bristol-Myers Squibb investigated differences in immune cell characteristics that may contribute to systemic lupus erythematosus severity in African-Americans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2016 Category: Global & Universal Source Type: news

Serology Matters in Lupus Benlysta Response (CME/CE)
(MedPage Today) -- Fewer severe flares seen with belimumab in patients with low complement, anti-dsDNA positivity (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - June 14, 2016 Category: Journals (General) Source Type: news

Multiple Lupus Types Raise Risk for CV Disease (CME/CE)
(MedPage Today) -- Local chronic inflammation in CLE and SLE may drive vascular events (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 14, 2016 Category: Rheumatology Source Type: news

Anti-Interferon Antibody Curbs Lupus Disease ActivityAnti-Interferon Antibody Curbs Lupus Disease Activity
After years of clinical trial failures, early evidence suggests an anti-interferon antibody, anifrolumab, reduces disease activity in systemic lupus erythematosus, and it appears to be well tolerated. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 14, 2016 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Low-Dose Aspirin for CV Prevention May Work in Lupus, Too (CME/CE)
(MedPage Today) -- But study too small to warrant guideline recommendation (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 14, 2016 Category: Rheumatology Source Type: news

Benlysta Seems to Cut Flares in Lupus (CME/CE)
(MedPage Today) -- Moderate-to-severe disease flares decreased by 30% at 12 months (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - June 13, 2016 Category: Journals (General) Source Type: news

Dramatic Results for Interferon Blocker in SLE (CME/CE)
(MedPage Today) -- "These are the best lupus data we've ever seen," researcher says of anifrolumab (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - June 12, 2016 Category: Journals (General) Source Type: news

Genetic clue to development of mouth ulcers in lupus
The results of a new study showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE). Linking the vascular endothelial growth factor (VEGF) genetic pathway with a specific disease characteristic among SLE patients represents an important step towards unravelling the genetic basis of different SLE clinical presentations. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 10, 2016 Category: Science Source Type: news

Medical News Today: Lupus raises women's risk of cervical cancer
Women with systemic lupus erythematosus are at double the risk of cervical dysplasia or invasive cervical cancer, a new study reveals. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 10, 2016 Category: Consumer Health News Tags: Lupus Source Type: news

Genetic clue to development of mouth ulcers in lupus
(European League Against Rheumatism) Genetic clue to development of mouth ulcers in lupus (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 10, 2016 Category: Global & Universal Source Type: news

Lupus may confer higher risk for cervical cancer
LONDON – Women with systemic lupus erythematosus (SLE) have more than twice the risk of developing cervical neoplasia than do women in the general population, according to the results of a large... (Source: Family Practice News)
Source: Family Practice News - June 9, 2016 Category: Primary Care Source Type: news

Lupus confirmed as risk factor for cervical cancer
The results of a study found a doubled risk of pre-malignant cervical changes, and potentially also an increased risk of cervical cancer, among women with Systemic Lupus Erythematosus (SLE) compared to the general female population. The highest risks were found in women with SLE who were treated with immunosuppressant drugs. These findings highlight the importance of regular cervical screening in all women with SLE, regardless of whether the increased risk is due to disease severity or treatment. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 9, 2016 Category: Science Source Type: news

Air pollution exposure may worsen lupus in children
The results of a new study show for the first time that an individual's exposure to air pollution may have a direct role in triggering disease activity as well as airway inflammation in children and adolescents with systemic lupus erythematosus. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 9, 2016 Category: Science Source Type: news

Lupus: Does Stress Affect Lupus?
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 6, 2016 Category: Journals (General) Source Type: news

Young people with lupus 'feel limited by their condition'
Young people with lupus are troubled by a feeling that their condition is limiting their opportunities in life, according to a new study.The Australian research, led by the University of Sydney, formed this conclusion after examining the experiences and perspectives of adolescents and young adults diagnosed with juvenile-onset systemic lupus erythematosus (SLE). The findings could help to inform strategies for improving treatment and health outcomes.The perceived social impact of lupus It is well known that disease activity, organ damage and treatment burden can often have a significant impact on young people with lupus, c...
Source: Arthritis Research UK - June 2, 2016 Category: Rheumatology Source Type: news

Novel Treatment Options Explored at Rheumatology CongressNovel Treatment Options Explored at Rheumatology Congress
Alternative therapies for rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus will be presented at the upcoming European League Against Rheumatism (EULAR) Congress 2016. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 2, 2016 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Dogs are twice as friendly to humankind as previously thought, suggests study
Study raises possibility that two populations of grey wolves, separated by thousands of miles and years, may have resulted in modern domestic dogsHumankind’s long friendship with the dog may have begun at least twice. Grey wolves in western Eurasia may have started hanging around Stone Age hunter-gatherer clans even before humans and dogs clinched the relationship perhaps 14,000 years ago in east Asia.New research based on DNA samples from prehistoric hounds, as well as genetic studies of modern dogs and wolves, suggests that two populations of grey wolves – separated by thousands of miles and thousands of year...
Source: Guardian Unlimited Science - June 2, 2016 Category: Science Authors: Tim Radford Tags: Genetics Archaeology Evolution Animal behaviour Science Wildlife Source Type: news

Lupus a Tough Disease to Spot, Treat
But experts say scientists are working to unearth genetic causes of autoimmune disorder Source: HealthDay Related MedlinePlus Page: Lupus (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 31, 2016 Category: Consumer Health News Source Type: news

Lupus a Tough Disease to Spot, Treat
Title: Lupus a Tough Disease to Spot, TreatCategory: Health NewsCreated: 5/30/2016 12:00:00 AMLast Editorial Review: 5/31/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - May 31, 2016 Category: Rheumatology Source Type: news

Lupus a tough disease to spot, treat
HealthDay News Lupus is difficult to diagnose and treat, but scientists are working to learn more about its genetic causes and to develop better treatments. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 30, 2016 Category: Consumer Health News Source Type: news

Lupus a Tough Disease to Spot, Treat
MONDAY, May 30, 2016 -- Lupus is difficult to diagnose and treat, but scientists are working to learn more about its genetic causes and to develop better treatments. The autoimmune disease affects between 300,000 and 1.5 million people in the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 30, 2016 Category: Journals (General) Source Type: news

Lupus patients 'at higher risk of developing other health conditions'
People with lupus are at a greater risk of developing other health conditions than members of the general population.This is according to a new study conducted by the University of Nottingham and the Arthritis Research UK Primary Care Centre at Keele University, which examined the frequency of comorbidities associated with systemic lupus erythematosus in the UK between 1999 and 2012.A broad UK study Published in the medical journal Arthritis Care & Research, the study drew upon data from the UK Clinical Practice Research Datalink, identifying cases of lupus and matching each one by age, gender and practice to four heal...
Source: Arthritis Research UK - May 26, 2016 Category: Rheumatology Source Type: news

[Editors' Choice] Lupus: subdivide in order to conquer?
Author: Paula A. Kiberstis (Source: ScienceNOW)
Source: ScienceNOW - May 26, 2016 Category: Science Authors: Paula A. Kiberstis Tags: Autoimmune Disease Source Type: news

Antiaging Yoga
by guest blogger Holly Walck Kostura, BSN and certified Iyengar Yoga teacher To quote Webster's: "Aging (adj): (of a thing) reaching the end of useful life; growing old or older, especially visibly and obviously so; obsolescent Obsolescent (adj): becoming obsolete Obsolete (adj): no longer produced or used; out-of-date." When I was 22 years old, a friend and I went into a local bookstore and saw a display of exercise videos, including one titled, Yoga for Beginners. The middle-aged woman demonstrating the pose on the cover looked strong, stable, flexible, and joyful, and I remember knowing that the way she l...
Source: Healthy Living - The Huffington Post - May 20, 2016 Category: Consumer Health News Source Type: news

Charlotte’s story: Overcoming lupus
A few months ago, Bonnie Godas, a Braintree mother of two, called a friend at the Massachusetts Statehouse asking a simple question. That friend phoned a friend at the Massachusetts Department of Transportation. Several phones calls later, Bonnie heard the news. On May 21, Boston’s iconic Zakim Bridge will be lit purple in recognition of Lupus Awareness Month. “I’m excited. I’m grateful and thrilled that Charlotte is doing so well,” says Bonnie. “It’s so important for parents to know about lupus because it can mask itself as other conditions like fibromyalgia and rheumatoid arthrit...
Source: Thrive, Children's Hospital Boston - May 20, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Diseases & Conditions Teen Health Dr. Robert Sundel lupus rheumatology program Source Type: news

Lupus More Severe in Kids, Large Study Confirms (CME/CE)
(MedPage Today) -- Mortality much higher than in adults with SLE (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - May 16, 2016 Category: Pediatrics Source Type: news

Study lays groundwork for refractory cutaneous lupus treatment algorithms
SCOTTSDALE, ARIZ. – Thalidomide, methotrexate, dapsone, and belimumab may be the best treatment alternatives for cutaneous lupus erythematosus that is refractory to antimalarials, based on reviews of 15 years of medical records from three large tertiary care centers. The study is the largest so... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 13, 2016 Category: Dermatology Source Type: news

NICE approves GSK's lupus drug Benlysta
The National Institute for Health and Care Excellence (NICE) has reportedly approved GlaxoSmithKline's (GSK) Benlysta for the treatment of lupus. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - May 11, 2016 Category: Pharmaceuticals Source Type: news

Nigeria: Save Okpokwu From Chronic Kidney Disease
[Guardian] Like every other young married lady, Mrs. Jacinta Okpokwu had her own plans about the future, but terminal sickness is at the verge of changing it. The 28-year-old lady, who hails from Aku in Igbo-Etiti Local Council of Enugu State, is battling to stay alive because of acute chronic kidney disease and Systemic Lupus Erythermatosus (SLE) attack. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 11, 2016 Category: African Health Source Type: news

UK cost body finally approves limited use of GSK's lupus drug
LONDON (Reuters) - Britain's healthcare cost watchdog has finally approved GlaxoSmithKline's lupus drug Benlysta for limited use, after rejecting it since 2011 on the grounds that it failed to offer good value for money. (Source: Reuters: Health)
Source: Reuters: Health - May 10, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

In the Loop: Curling for a Cause: 'Lupus 'Spiel USA' Raises Funds for Research
This story originally appeared on the In the Loop blog. _________________________________________________ Regan Birr was diagnosed with lupus when she was 21 years old. In the years since, she tells us her road to recovery has been a long and winding one. "When I first got sick, I had extreme pain and fatigue all over my body," she says. [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 9, 2016 Category: Databases & Libraries Source Type: news

Lupus Awareness Month: Shining Light on a Dark Disease
'Some patients will live their life on a nonstop roller-coaster ride of being abled and disabled, in a flare and in remission.' (Source: U.S. News - Health)
Source: U.S. News - Health - May 9, 2016 Category: Consumer Health News Authors: Marisa Zeppieri-Caruana Source Type: news

Association Between Diet and Glucocorticoid Treatment in SLEAssociation Between Diet and Glucocorticoid Treatment in SLE
Can the risk for and severity of systemic lupus erythematosus be modified by diet? Lupus Science & Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 6, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Antibody targets and destroys cells implicated in systemic lupus erythmatosis
(Journal of Clinical Investigation) In this issue of JCI Insight, research groups led by Ian Wicks of the University of Melbourne and Nicholas Wilson of CSL Limited developed an antibody (CSL362) directed against the surface molecule CD123 that targets and depletes pDCs and other cells implicated in SLE. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 5, 2016 Category: Global & Universal Source Type: news

Listening to lupus
Lupus is a mysterious chronic illness that primarily affects women in their prime of life. In people with lupus, the immune system goes awry, attacking healthy tissue. While there is no cure, there are many options for treatment, including ones being studied at Yale School of Medicine. For May, lupus awareness month, YaleNews spoke to Dr. Lenore Buckley, professor of medicine in the Section of Rheumatology, who recently launched an innovative clinical program for patients with lupus. (Source: Yale Science and Health News)
Source: Yale Science and Health News - May 4, 2016 Category: Universities & Medical Training Tags: Yale News Source Type: news

Probiotic supplements 'could help prevent menopause-associated bone loss'
Bone loss associated with the menopause could potentially be addressed through the use of probiotic supplements.This is according to new research from the Emory University School of Medicine and Georgia State University in the US, which conducted an experiment with mice and discovered evidence that probiotic bacteria may have potential as an affordable treatment for postmenopausal osteoporosis.Encouraging results The study involved the use of mice that had had their ovaries removed, meaning the animals underwent the same hormonal changes that occur when women reach the menopause.It was shown that the resulting loss of oest...
Source: Arthritis Research UK - May 2, 2016 Category: Rheumatology Source Type: news

Can Artificial Intelligence Identify Your Next Heart Attack?
This study will be evaluating outcomes based on patients who are going for a coronary angiogram, the gold standard in identifying blockages in the coronary arteries. These AI algorithms will develop over time and can be further refined with more data. The hope is that these algorithms will eventually lead to developing a lexicon that can help identify cardiovascular disease in women and men based on how they describe their symptoms. From a medical standpoint, the implications of using linguistic AI algorithms are substantial. When calling 911 for help, based on how and what someone says, these AI algorithms may identify s...
Source: Science - The Huffington Post - April 29, 2016 Category: Science Source Type: news

New studies published in Nature Immunology further understanding of immune system
(MedImmune, Inc.) MedImmune, the global biologics research and development arm of AstraZeneca, today announced that it has achieved a significant scientific milestone by publishing three manuscripts in Nature Immunology that advance the understanding of the immune system and highlight underlying mechanisms in two little-understood disease areas -- chronic obstructive pulmonary disease (COPD) and systemic lupus erythematosus (SLE). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 25, 2016 Category: Global & Universal Source Type: news

Defects in body's cell disposal system may contribute to the most common form of lupus
Scientists may be setting the stage for new approaches to control or prevent the inflammation and tissue damage associated with the chronic autoimmune disorder lupus. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 20, 2016 Category: Science Source Type: news

Kidney Lesions Predict Poor Outcomes in Lupus (CME/CE)
(MedPage Today) -- The presence of more crescents presaged ESRD, death (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 20, 2016 Category: Primary Care Source Type: news

Role for oxidized mitochondrial DNA in lupus revealed
The neutrophils of systemic lupus erythematosus patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response, researchers have discovered. The study suggests that targeting the pathways that lead to the accumulation of this DNA and/or facilitate its removal could be new ways to treat this chronic autoimmune disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 18, 2016 Category: Science Source Type: news

Baylor study reveals role for oxidized mitochondrial DNA in lupus
(Rockefeller University Press) Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response. The study, which will be published online April 18 in The Journal of Experimental Medicine, suggests that targeting the pathways that lead to the accumulation of this DNA and/or facilitate its removal could be new ways to treat this chronic autoimmune disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 18, 2016 Category: Global & Universal Source Type: news

Well: Ask Well: Why Is Arthritis More Common in Women Than Men?
More women than men get arthritis over all, but there are many types of arthritis, and some types are more common in men. (Source: NYT Health)
Source: NYT Health - April 14, 2016 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Arthritis Autoimmune Diseases Lupus Erythematosus Osteoarthritis Rheumatoid Arthritis Women and Girls Aging Ask Well Featured Live Source Type: news

UCLA research suggests that gut bacteria could help prevent cancer
Researchers have shown that various types of intestinal bacteria might be factors in both causing and preventing obesity, and in other conditions and diseases. Now, a UCLA study suggests that it could also potentially be used to reduce the risk for some types of cancer. The research, published online April 13 in the peer-reviewed journal PLOS ONE, offers evidence that anti-inflammatory “health beneficial” gut bacteria can slow or stop the development of some types of cancer. Ultimately, doctors might be able to reduce a person’s risk for cancer by analyzing the levels and types of intestinal bacteria in...
Source: UCLA Newsroom: Health Sciences - April 13, 2016 Category: Universities & Medical Training Source Type: news

CV Events Strike Early in Lupus (CME/CE)
(MedPage Today) -- Myocardial infarctions can occur even before lupus is diagnosed (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 13, 2016 Category: Primary Care Source Type: news