Another Study Backs Treatment for Preclinical Rheumatoid Arthritis
(MedPage Today) -- Inflammatory markers were reduced in patients with persistent joint pain and other markers for incipient rheumatoid arthritis (RA), as was progression to formal RA diagnosis, after a 6-month course of abatacept (Orencia) in a... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 16, 2024 Category: Rheumatology Source Type: news

Senators Thrash Pharma CEOs for Pricing Drugs Higher in the U.S.
(MedPage Today) -- Senators pummeled the CEOs of three of the largest pharmaceutical companies with demands that they explain why one in four Americans can't afford their prescription drugs, prices of which are higher in the U.S. compared with... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 9, 2024 Category: Rheumatology Source Type: news

Novel Lupus Approach Yields Mixed Results in Early Trial
(MedPage Today) -- A drug engineered to "digest" extracellular RNA missed its primary endpoint in an early-stage clinical trial in systemic lupus erythematosus (SLE), though patients with higher disease activity scores did appear to show some improvement... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 8, 2024 Category: Rheumatology Source Type: news

A Clue on Why Lupus, Other Autoimmune Diseases Strike Far More Women Than Men
(MedPage Today) -- Women are far more likely than men to get autoimmune diseases, when an out-of-whack immune system attacks their own bodies -- and new research may finally explain why. It's all about how the body handles females' extra X chromosome... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 2, 2024 Category: Rheumatology Source Type: news

Yes, Lupus Patients Can Stop MMF Treatment
(MedPage Today) -- Among patients with systemic lupus erythematosus (SLE) managed successfully with mycophenolate mofetil (MMF), rates of disease flare were not massively greater when the drug was withdrawn over several months versus kept at their... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 31, 2024 Category: Rheumatology Source Type: news

Could Arthritis Enhance Male Fertility?
(MedPage Today) -- Infertility does not seem to be a problem for men with inflammatory joint diseases, a large Scandinavian study indicated. In fact, men with arthritis showed lower rates of childlessness relative to a control group, and had fathered... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 23, 2024 Category: Rheumatology Source Type: news

Study Slams Community Rheum Docs for Sloppy RA Management
(MedPage Today) -- Guideline recommendations for use of tumor necrosis factor (TNF) inhibitors in people with rheumatoid arthritis (RA) were only infrequently followed in independent, community-based rheumatology practices, researchers found.... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 18, 2024 Category: Rheumatology Source Type: news

This Biomarker Predicts Survival in Autoimmune Lung Disease
(MedPage Today) -- One major subgroup of patients with interstitial lung disease (ILD) arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 28, 2023 Category: Rheumatology Source Type: news

A New Test Could Save Arthritis Patients Time, Money, and Pain
(MedPage Today) -- SAN DIEGO -- Erinn Maury, MD, knew infliximab (Remicade) wasn't the right drug for Patti Schulte, a rheumatoid arthritis patient the physician saw at her Millersville, Maryland, practice. Schulte's swollen, painful joints hadn... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 23, 2023 Category: Rheumatology Source Type: news

Axial SpA: Gender Gap Confirmed in TNF Inhibitor Response
(MedPage Today) -- Men with axial spondyloarthritis (axSpA) were more likely than women to obtain substantial relief with tumor necrosis factor (TNF) inhibitors, a multinational study indicated. After 6 months of treatment with these agents, 66... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 15, 2023 Category: Rheumatology Source Type: news

Opioid Antagonist Flops as Fibromyalgia Therapy
(MedPage Today) -- Patients with fibromyalgia got no more pain relief from low-dose naltrexone than from placebo in a randomized trial, researchers said, dashing hopes that the opioid receptor antagonist might succeed where others have failed... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 8, 2023 Category: Rheumatology Source Type: news

Improvements With Guselkumab in Psoriatic Arthritis Seen Across All MDA Domains
(MedPage Today) -- At the American College of Rheumatology annual meeting, results from the phase IIIb COSMOS trial were presented that examined the association between patient- and physician-reported domains and minimal disease activity (MDA... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 6, 2023 Category: Rheumatology Source Type: news

Could Correcting Metabolic Dysfunction Treat Rheumatoid Arthritis?
(MedPage Today) -- Alterations in tryptophan metabolism are common among patients with rheumatoid arthritis (RA), researchers found, and preclinical studies suggest that correcting them is a viable treatment strategy. Participants in France's... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 28, 2023 Category: Rheumatology Source Type: news

Another Long-Acting Steroid Shot Impresses in Knee OA
(MedPage Today) -- SAN DIEGO -- Two intra-articular injections of a liposomal formulation of dexamethasone given 6 months apart provided a year of pain relief for patients with osteoarthritis (OA) of the knee, a researcher said here. In a phase... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 16, 2023 Category: Rheumatology Source Type: news

Novel Gout Drug Aces Mid-Stage Tests
(MedPage Today) -- SAN DIEGO -- An investigational once-daily oral agent that inhibits urate transporter-1 (URAT1) as a means of forcing uric acid excretion showed good efficacy and safety in a pair of phase II trials reported here. In one of... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 16, 2023 Category: Rheumatology Source Type: news