Myxoid pleomorphic liposarcoma
Histol Histopathol. 2024 Feb 26:18724. doi: 10.14670/HH-18-724. Online ahead of print.ABSTRACTMyxoid pleomorphic liposarcoma (MPL) is an extremely rare adipocytic tumor, recently recognized as a distinct entity in the 5th edition of the World Health Organization (WHO) Classification of Soft Tissue and Bone Tumors. Predominantly found in the mediastinum of young women, MPLs exhibit a combination of histological features characteristic of myxoid liposarcoma and pleomorphic (lipo)sarcoma. Their unique molecular features distinguish MPLs from other liposarcomas. Unlike myxoid liposarcomas and well-differentiated/dedifferentiat...
Source: Histology and Histopathology - March 7, 2024 Category: Cytology Authors: Sharareh Fadaei Fleur Cordier Liesbeth Ferdinande Jo Van Dorpe David Creytens Source Type: research
ASO Visual Abstract: Adjuvant Palbociclib May be Associated with Delayed Recurrence in Completely Resected Retroperitoneal Liposarcoma: Results of a Single-Institution Retrospective Cohort Study
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - March 4, 2024 Category: Cancer & Oncology Source Type: research
Spot scanning proton therapy for unresectable bulky retroperitoneal dedifferentiated liposarcoma: a case report
AbstractThe development of effective treatment strategies for unresectable retroperitoneal sarcoma is desirable. Herein, we suggest that definitive proton therapy (PT) could be a promising treatment option, regardless of the large size of the tumor. A 52-year-old man presented with a discomfort of the lower abdomen. Computed tomography revealed a retroperitoneal tumor, measuring over 20 cm in the largest dimensions, which was surrounded by the gastrointestinal (GI) tract. Biopsy revealed dedifferentiated liposarcoma. Neoadjuvant chemotherapy was ineffective, and the tumor was ultimately deemed unresectable. The patient o...
Source: International Cancer Conference Journal - March 2, 2024 Category: Cancer & Oncology Source Type: research
Myxoid Liposarcoma of the Parotid Gland
Ear Nose Throat J. 2024 Feb 29:1455613241235499. doi: 10.1177/01455613241235499. Online ahead of print.ABSTRACTLiposarcoma is extremely rare in the parotid gland. In this article, we report the case of an 87-year-old man who presented to our department with swelling in the left parotid region. Magnetic resonance imaging (MRI) revealed a tumor in the superficial lobe of the parotid gland. Total parotidectomy and ipsilateral lymph node dissection were performed. Histologic examination confirmed the diagnosis of myxoid liposarcoma of the parotid gland. On imaging, there was no evidence of nodal or distant metastasis. Radiatio...
Source: Ear, Nose and Throat Journal - March 1, 2024 Category: ENT & OMF Authors: Sameh Mezri Chaima Zitouni Wadii Thabet Chaima Ben Amar Karima Tlili Fethi Bougrine Khemaies Akari Source Type: research
Myxoid Liposarcoma of the Parotid Gland
Ear Nose Throat J. 2024 Feb 29:1455613241235499. doi: 10.1177/01455613241235499. Online ahead of print.ABSTRACTLiposarcoma is extremely rare in the parotid gland. In this article, we report the case of an 87-year-old man who presented to our department with swelling in the left parotid region. Magnetic resonance imaging (MRI) revealed a tumor in the superficial lobe of the parotid gland. Total parotidectomy and ipsilateral lymph node dissection were performed. Histologic examination confirmed the diagnosis of myxoid liposarcoma of the parotid gland. On imaging, there was no evidence of nodal or distant metastasis. Radiatio...
Source: Ear, Nose and Throat Journal - March 1, 2024 Category: ENT & OMF Authors: Sameh Mezri Chaima Zitouni Wadii Thabet Chaima Ben Amar Karima Tlili Fethi Bougrine Khemaies Akari Source Type: research
Myxoid Liposarcoma of the Parotid Gland
Ear Nose Throat J. 2024 Feb 29:1455613241235499. doi: 10.1177/01455613241235499. Online ahead of print.ABSTRACTLiposarcoma is extremely rare in the parotid gland. In this article, we report the case of an 87-year-old man who presented to our department with swelling in the left parotid region. Magnetic resonance imaging (MRI) revealed a tumor in the superficial lobe of the parotid gland. Total parotidectomy and ipsilateral lymph node dissection were performed. Histologic examination confirmed the diagnosis of myxoid liposarcoma of the parotid gland. On imaging, there was no evidence of nodal or distant metastasis. Radiatio...
Source: Ear, Nose and Throat Journal - March 1, 2024 Category: ENT & OMF Authors: Sameh Mezri Chaima Zitouni Wadii Thabet Chaima Ben Amar Karima Tlili Fethi Bougrine Khemaies Akari Source Type: research
Myxoid Liposarcoma of the Parotid Gland
Ear Nose Throat J. 2024 Feb 29:1455613241235499. doi: 10.1177/01455613241235499. Online ahead of print.ABSTRACTLiposarcoma is extremely rare in the parotid gland. In this article, we report the case of an 87-year-old man who presented to our department with swelling in the left parotid region. Magnetic resonance imaging (MRI) revealed a tumor in the superficial lobe of the parotid gland. Total parotidectomy and ipsilateral lymph node dissection were performed. Histologic examination confirmed the diagnosis of myxoid liposarcoma of the parotid gland. On imaging, there was no evidence of nodal or distant metastasis. Radiatio...
Source: Ear, Nose and Throat Journal - March 1, 2024 Category: ENT & OMF Authors: Sameh Mezri Chaima Zitouni Wadii Thabet Chaima Ben Amar Karima Tlili Fethi Bougrine Khemaies Akari Source Type: research
ASO Author Reflections: Multivisceral Versus Tumor-Only Resection in Retroperitoneal Liposarcoma
Ann Surg Oncol. 2024 Feb 26. doi: 10.1245/s10434-024-15090-6. Online ahead of print.NO ABSTRACTPMID:38409372 | DOI:10.1245/s10434-024-15090-6 (Source: Ann Oncol)
Source: Ann Oncol - February 27, 2024 Category: Cancer & Oncology Authors: Amblessed Onuma Leva Gorji Joal D Beane Source Type: research
ASO Author Reflections: Multivisceral Versus Tumor-Only Resection in Retroperitoneal Liposarcoma
Ann Surg Oncol. 2024 Feb 26. doi: 10.1245/s10434-024-15090-6. Online ahead of print.NO ABSTRACTPMID:38409372 | DOI:10.1245/s10434-024-15090-6 (Source: Ann Oncol)
Source: Ann Oncol - February 27, 2024 Category: Cancer & Oncology Authors: Amblessed Onuma Leva Gorji Joal D Beane Source Type: research
Dose-Escalated Preoperative Proton Therapy for Retroperitoneal Sarcomas: Initial Outcomes of a New Treatment Paradigm
CONCLUSIONS: In our RPS cohort, preoperative dose-escalated RT to 63 Gy demonstrated comparable local control without G3 acute toxicities. Given the high local recurrence rates of RPS, this approach warrants further study to validate these results and identify patients most likely to benefit from therapy.PMID:38406389 | PMC:PMC10884413 | DOI:10.1016/j.adro.2023.101431 (Source: Cancer Control)
Source: Cancer Control - February 26, 2024 Category: Cancer & Oncology Authors: Sreenija Yarlagadda Tugce Kutuk Ramon E Jimenez Muni B Rubens Matthew Hall Nicole T Eiseler Noah S Kalman Source Type: research
Liposarcoma of tongue: A case report
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_448_23. Online ahead of print.ABSTRACTLiposarcoma (LS) is one of the most common malignant tumors. However, oral LS is an extremely rare lesion that is often clinically misdiagnosed as a benign lesion because of its asymptomatic and indolent clinical course. In oral cavity, the tongue is the most frequent site for its occurrence.PMID:38394426 | DOI:10.4103/ijpm.ijpm_448_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Amarjot Kaur Aminder Singh Vikram Narang Chandan Kakkar Source Type: research
Primary liposarcoma of the uterus with MDM2 negative
We report a 37-year-old woman presented with lower abdominal discomfort and increase in vaginal secretions for more than 2 months. The ultrasonography revealed a hypoechoic mass sized 81 × 73 × 67 mm in the right adnexal area. Histopathologically, the neoplasm was mainly composed of mature adipose tissue, a small number of scattered lipoblasts, and the spindle cell which with mild atypia. Immunohistochemistry showed that the tumor cells were positive for CDK4 but negative for MDM2, and FISH analysis showed no MDM2 amplification. The patient only underwent tumor excision and is currently doing well.PMID:38394412 | DOI:10....
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Shufei Wei Lushun Zhang Yongliang Han Liangliang Wang Source Type: research
