Gender Differences in Prognosis After Primary Resection for Retroperitoneal Liposarcoma
CONCLUSION: Men may have worse survival after primary resection of RLPS compared with women, especially in patients with low-grade tumors or patients who received non-radical resection. Gender-based disparities may deserve more attention in patients with RLPS.PMID:37728273 | DOI:10.1177/00031348231201883 (Source: The American Surgeon)
Source: The American Surgeon - September 20, 2023 Category: Surgery Authors: Li Ren Yuhan Qi Jichun Zhao Chengxin Weng Jiarong Wang Ding Yuan Tiehao Wang Source Type: research
Successful Shoulder Disarticulation under Local Anesthesia in the COVID-19 Era
We report the case of an older patient with an arm liposarcoma for which surgery under general or regional anesthesia was deemed unsafe, but was successfully managed with a curative right shoulder disarticulation using tumescent local anesthesia.PMID:37711723 | PMC:PMC10499080 | DOI:10.1097/GOX.0000000000005266 (Source: Hand Surgery)
Source: Hand Surgery - September 15, 2023 Category: Surgery Authors: Pitman Mbabazi Mercy Mwaniki Gloria Wambua Samuel Kagua Rosemary Wangari Kamau Justin Daggett Peter M Nthumba Source Type: research
Successful Shoulder Disarticulation under Local Anesthesia in the COVID-19 Era
We report the case of an older patient with an arm liposarcoma for which surgery under general or regional anesthesia was deemed unsafe, but was successfully managed with a curative right shoulder disarticulation using tumescent local anesthesia.PMID:37711723 | PMC:PMC10499080 | DOI:10.1097/GOX.0000000000005266 (Source: Hand Surgery)
Source: Hand Surgery - September 15, 2023 Category: Surgery Authors: Pitman Mbabazi Mercy Mwaniki Gloria Wambua Samuel Kagua Rosemary Wangari Kamau Justin Daggett Peter M Nthumba Source Type: research
Myxoid liposarcoma with nuclear pleomorphism: a clinicopathological and molecular study
In this study, we conducted an in-depth investigation of four MLS tumors that demonstrated nuclear pleomorphism in three patients. These cases accounted for 2.1% of 142 patients with MLS. All patients were male aged 26, 33, and 49 years. Nuclear pleomorphism was observed in both primary and metastatic tumors in one patient, a primary tumor in one patient, and a metastatic tumor in another patient. Pleomorphism was severe in three tumors and moderate in one. Histology resembled that of dedifferentiated liposarcoma with myxoid features, pleomorphic liposarcoma with myxoid features, or myxoid pleomorphic liposarcoma in two tu...
Source: Virchows Archiv - September 13, 2023 Category: Pathology Source Type: research
Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma
CONCLUSIONS: Abemaciclib was well tolerated and showed promising activity in DDLS. The discovery of ANGPTL4 as a late regulator of geroconversion helped to define how cellular senescence modulates the immune tumor microenvironment and contributes to both positive and negative clinical outcomes.PMID:37695642 | DOI:10.1158/1078-0432.CCR-23-2378 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - September 11, 2023 Category: Cancer & Oncology Authors: Caroline E Gleason Mark A Dickson Mary E Klein Dooley Cristina R Antonescu Rodrigo Gularte-M érida Marimar Benitez Juliana I Delgado Raghu P Kataru Mark Wei Yi Tan Martina Bradic Travis E Adamson Kenneth Seier Allison L Richards Marta Palafox Eric Chan S Source Type: research
Lipomas: genetic basis of common skin lesions and their occurrence in rare diseases
This study aims to present the genetic basis of lipomas and diseases in which these lesions occur in the clinical picture.PMID:37692275 | PMC:PMC10485760 | DOI:10.5114/ada.2023.129529 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - September 11, 2023 Category: Dermatology Authors: Dorota Marzy ńska Ryszard Żaba Katarzyna Lacka Source Type: research
Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma
CONCLUSIONS: Abemaciclib was well tolerated and showed promising activity in DDLS. The discovery of ANGPTL4 as a late regulator of geroconversion helped to define how cellular senescence modulates the immune tumor microenvironment and contributes to both positive and negative clinical outcomes.PMID:37695642 | DOI:10.1158/1078-0432.CCR-23-2378 (Source: Cell Research)
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Caroline E Gleason Mark A Dickson Mary E Klein Dooley Cristina R Antonescu Rodrigo Gularte-M érida Marimar Benitez Juliana I Delgado Raghu P Kataru Mark Wei Yi Tan Martina Bradic Travis E Adamson Kenneth Seier Allison L Richards Marta Palafox Eric Chan S Source Type: research
Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma
CONCLUSIONS: Abemaciclib was well tolerated and showed promising activity in DDLS. The discovery of ANGPTL4 as a late regulator of geroconversion helped to define how cellular senescence modulates the immune tumor microenvironment and contributes to both positive and negative clinical outcomes.PMID:37695642 | DOI:10.1158/1078-0432.CCR-23-2378 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - September 11, 2023 Category: Cancer & Oncology Authors: Caroline E Gleason Mark A Dickson Mary E Klein Dooley Cristina R Antonescu Rodrigo Gularte-M érida Marimar Benitez Juliana I Delgado Raghu P Kataru Mark Wei Yi Tan Martina Bradic Travis E Adamson Kenneth Seier Allison L Richards Marta Palafox Eric Chan S Source Type: research
Lipomas: genetic basis of common skin lesions and their occurrence in rare diseases
This study aims to present the genetic basis of lipomas and diseases in which these lesions occur in the clinical picture.PMID:37692275 | PMC:PMC10485760 | DOI:10.5114/ada.2023.129529 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - September 11, 2023 Category: Dermatology Authors: Dorota Marzy ńska Ryszard Żaba Katarzyna Lacka Source Type: research
