A Year in Review: FDA 2015 New Drug Approvals
The approval of first-of-a-kind drugs rose last year to forty-one, resulting in the highest level of newly approved U.S. drugs in nineteen years. The total number of new drugs approved last year was even higher at sixty-nine. The rising figures reflect an industry-wide desire to research and develop drugs for rare and hard-to-treat diseases.
The newly approved drugs serve to advance medical care and the health of patients suffering from many ailments, including various forms of cancer, heart failure, and cystic fibrosis. Additionally, more than 40% of the new therapies were approved for treatment of rare or "orphan" dise...
Source: Policy and Medicine - January 13, 2016 Category: American Health Authors: Thomas Sullivan - Policy & Medicine Writing Staff Source Type: blogs
In the beginning…liposarcoma – Guest Post
New diagnosis, new survivor, new journey, new blog. ~ I Dream of a Cure….. The beginning…. Hi!!! I’m Jeanne (hence the “I dream of” title) I am- well was- but am- a healthy happy funny kick ass chick! I’m a … Continue reading → (Source: Being Cancer Network)
Source: Being Cancer Network - August 27, 2013 Category: Cancer Authors: Dennis Pyritz Tags: Guest Post * Sarcoma Source Type: blogs
Sarcoma – Signs, Histology, and Treatment
Pathophysiology of Soft Tissue Sarcoma
1) sarcomas of the soft tissue are a family of neoplasms affecting the soft tissue of the body Causes 2) previous radiation 3) HIV 4) genetic predisposition such as L-Fraumeni syndrome 5) asbestosis 6) congenital immunodeficiences 7) dioxin exposure 8) Herpes virus
Signs and Symptoms
1) most common presentation is an enlarging mass 2) pain 3) neuralgia and neurologic deficits, if the tumor encases a nerve structure 4) metastases are usually via the blood system and most commonly go to the lungs
Characteristic Test Findings
Radiology – mass on MRI
Histology/Gross Pathology
1) m...
Source: Inside Surgery - January 27, 2013 Category: Surgeons Authors: Editor Tags: Oncology angiosarcoma leimyosarcoma malignant fibrous histiocytosis p53 Schwannoma tumor suppressor Source Type: blogs
Overselling p53 Drugs
You may have seen some "wonder drug" news stories over the holiday break about compounds targeting p53 - many outlets picked up this New York Times story. The first paragraph probably got them:
For the first time ever, three pharmaceutical companies are poised to test whether new drugs can work against a wide range of cancers independently of where they originated — breast, prostate, liver, lung. The drugs go after an aberration involving a cancer gene fundamental to tumor growth. Many scientists see this as the beginning of a new genetic age in cancer research.
Now, to read that, you might think we're talking mutated ...
Source: In the Pipeline - January 3, 2013 Category: Chemists Tags: Cancer Source Type: blogs
