Hydrochlorothiazide use is strongly associated with risk of lip cancer
ConclusionsHydrochlorothiazide use is strongly associated with an increased risk of lip cancer.This article is protected by copyright. All rights reserved. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - May 1, 2017 Category: Internal Medicine Authors: Anton Potteg ård, Jesper Hallas, Morten Olesen, Mathias T. Svendsen, Laurel A. Habel, Gary D. Friedman, Søren Friis Tags: Original Source Type: research

Changes in the Incidence of Skin and Lip Cancer Between 1978 and 2007
Conclusions The rise in the incidence of skin cancer, assessed using age-standardized rates, suggests that primary prevention measures are insufficient or inappropriate. The reduction in the incidence of cutaneous melanoma in Australia between 2003 and 2007 suggests that the preventive strategies initiated several decades earlier in that country have been effective. (Source: Actas Dermo-Sifiliograficas)
Source: Actas Dermo-Sifiliograficas - April 13, 2017 Category: Dermatology Source Type: research

154 Antihypertensive drugs and cutaneous squamous cell carcinoma in non-Hispanic whites
We examined the association between AD use and cSCC risk among a cohort of non-Hispanic whites (NHWs) with hypertension (n=28,357) in the Kaiser Permanente Northern California health plan. Electronic pharmacy data were used to determine exposure to ADs, which we classified as photosensitizing (alpha-2 receptor agonists and diuretics [loop, potassium-sparing, thiazide, and combination]), non-photosensitizing (alpha-blockers, beta-blockers, central agonists, peripheral adrenergic inhibitors, and angiotensin receptor blockers), or unknown (angiotensin converting enzyme inhibitors, calcium channel blockers, vasodilators, and o...
Source: Journal of Investigative Dermatology - April 12, 2017 Category: Dermatology Authors: K. Levandoski, L. Habel, N. Achacoso, G. Friedman, M. Asgari Tags: Clinical Research: Epidemiology of Skin Diseases Source Type: research

Incidence of lip malignancies in Germany —data from nine population‐based cancer registries
ConclusionsThe incidences of non‐melanoma skin cancer of the lip increased over time in Germany in both sexes. Lip cancer incidence increased in women, while it stayed stable in men. Melanoma of the lip did not change in incidence. The distribution of histology in non‐melanoma skin cancer of the lip differed by sex. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - March 1, 2017 Category: Pathology Authors: Susanne Singer, Sylke Ruth Zeissig, Katharina Emrich, Bernd Holleczek, Klaus Kraywinkel, Meike Ressing Tags: Original Article Source Type: research

Changes in the Incidence of Skin and Lip Cancer Between 1978 and 2007.
CONCLUSIONS: The rise in the incidence of skin cancer, assessed using age-standardized rates, suggests that primary prevention measures are insufficient or inappropriate. The reduction in the incidence of cutaneous melanoma in Australia between 2003 and 2007 suggests that the preventive strategies initiated several decades earlier in that country have been effective. PMID: 28190452 [PubMed - as supplied by publisher] (Source: Actas Dermo-Sifiliograficas)
Source: Actas Dermo-Sifiliograficas - February 8, 2017 Category: Dermatology Authors: Martín García E, Arias-Santiago S, Serrano-Ortega S, Buendía-Eisman A Tags: Actas Dermosifiliogr Source Type: research

Incidence of lip malignancies in Germany – data from 9 population‐based cancer registries
ConclusionsThe incidences of non‐melanoma skin cancer of the lip increased over time in Germany in both sexes. Lip cancer incidence increased in women, while it stayed stable in men. Melanoma of the lip did not change in incidence. The distribution of histology in non‐melanoma skin cancer of the lip differed by sex.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - February 7, 2017 Category: Pathology Authors: S. Singer, S. R. Zeissig, K. Emrich, B. Holleczek, K. Kraywinkel, M. Ressing Tags: Original Article Source Type: research

HDR and LDR Brachytherapy in the Treatment of Lip Cancer: the Experience of the Catalan Institute of Oncology.
CONCLUSIONS: Our findings confirm that brachytherapy is an effective treatment for lip cancer. The results from our series are in line with those published elsewhere. Based on our limited data, HDR appears to be equally as good as LDR, although this needs to be confirmed by further studies. PMID: 28031737 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 1, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Long term results of PDR brachytherapy for lip cancer.
CONCLUSIONS: Local outcome is excellent and similar to other published studies of continuous low dose rate (cLDR) brachytherapy. PMID: 27895671 [PubMed - in process] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 4, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Oral cavity and lip cancer: United Kingdom National Multidisciplinary Guidelines.
Authors: Kerawala C, Roques T, Jeannon JP, Bisase B Abstract This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. It provides recommendations on the assessment and management of patients with cancer of the oral cavity and the lip. Recommendations • Surgery remains the mainstay of management for oral cavity tumours. (R) • Tumour resection should be performed with a clinical clearance of 1 cm vital structures permitting. (R) • Elective neck treatment should be offered for all oral cavity tumours. (R) • Adjuvant radioche...
Source: Journal of Laryngology and Otology - November 15, 2016 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Podoplanin, ezrin, and Rho-A proteins may have joint participation in tumor invasion of lip cancer
ConclusionsTherefore, our results confirm a correlation among podoplanin, ezrin, and Rho-A expressions in squamous cell carcinoma of the lip suggesting a cooperative participation of these proteins in cell movement and invasion.Clinical relevanceFurthermore, strong cytoplasmic podoplanin expression could be helpful to identify patients with squamous cell carcinoma of the lip and lower risk of loco-regional recurrences. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - September 13, 2016 Category: Dentistry Source Type: research

A Gaussian random field model for similarity-based smoothing in Bayesian disease mapping
Conditionally specified Gaussian Markov random field (GMRF) models with adjacency-based neighbourhood weight matrix, commonly known as neighbourhood-based GMRF models, have been the mainstream approach to spatial smoothing in Bayesian disease mapping. In the present paper, we propose a conditionally specified Gaussian random field (GRF) model with a similarity-based non-spatial weight matrix to facilitate non-spatial smoothing in Bayesian disease mapping. The model, named similarity-based GRF, is motivated for modelling disease mapping data in situations where the underlying small area relative risks and the associated det...
Source: Statistical Methods in Medical Research - August 25, 2016 Category: Statistics Authors: Baptista, H., Mendes, J. M., MacNab, Y. C., Xavier, M., Caldas-de-Almeida, J. Tags: Special Issue Articles Source Type: research

Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer
Conclusions Cleaved caspase-3 immunoexpression showed differences in oral SCCs and PMDs and demonstrated a distinct role of apoptosis in carcinogenesis of intraoral and lower lip cancer. In future, the expression of cleaved caspase-3 with other target molecules in oral cancer may be helpful in delineating the prognosis and treatment of these tumors. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - August 23, 2016 Category: Dentistry Source Type: research

Two ‐Piece Extraoral Prosthetic Rehabilitation to a Perineural Invasion Lip Cancer
Journal of Prosthodontics,Volume 27, Issue 3, Page 306-310, March 2018. (Source: Journal of Prosthodontics)
Source: Journal of Prosthodontics - August 12, 2016 Category: Dentistry Source Type: research

Two ‐Piece Extraoral Prosthetic Rehabilitation to a Perineural Invasion Lip Cancer
Abstract Lip cancers can severely affect a person in terms of function, esthetics, and psychological trauma. After surgical resection, lip defects require special rehabilitation. This clinical report describes a neck prosthesis of a male patient diagnosed with lower lip squamous cell carcinoma with perineural involvement. The neck prosthesis was connected to the mandibular complete denture with cobalt samarium magnets. Both prostheses improved the patient's mastication, deglutition, and esthetics. (Source: Journal of Prosthodontics)
Source: Journal of Prosthodontics - August 11, 2016 Category: Dentistry Authors: Makbule Heval Şahan, Görkem Eskiizmir, Pınar Ateş Tags: Original Manuscript Source Type: research

Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas
ConclusionsThe results suggested that DNMT 3a could play a key role in the methylation process of initial steps of UV carcinogenesis present in AC while DNMT 3b could be responsible for de novo methylation in already established lip cancer. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - April 30, 2016 Category: Pathology Authors: Filipe I. Daniel, Soraia R. Alves, Daniella S. C. Vieira, Michelle T. Biz, Inah W. B. S. Daniel, Filipe Modolo Tags: Original Article Source Type: research