Oral cavity and lip cancer: United Kingdom National Multidisciplinary Guidelines.
Authors: Kerawala C, Roques T, Jeannon JP, Bisase B
Abstract
This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. It provides recommendations on the assessment and management of patients with cancer of the oral cavity and the lip. Recommendations • Surgery remains the mainstay of management for oral cavity tumours. (R) • Tumour resection should be performed with a clinical clearance of 1 cm vital structures permitting. (R) • Elective neck treatment should be offered for all oral cavity tumours. (R) • Adjuvant radioche...
Source: Journal of Laryngology and Otology - November 15, 2016 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
Podoplanin, ezrin, and Rho-A proteins may have joint participation in tumor invasion of lip cancer
ConclusionsTherefore, our results confirm a correlation among podoplanin, ezrin, and Rho-A expressions in squamous cell carcinoma of the lip suggesting a cooperative participation of these proteins in cell movement and invasion.Clinical relevanceFurthermore, strong cytoplasmic podoplanin expression could be helpful to identify patients with squamous cell carcinoma of the lip and lower risk of loco-regional recurrences. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - September 13, 2016 Category: Dentistry Source Type: research
A Gaussian random field model for similarity-based smoothing in Bayesian disease mapping
Conditionally specified Gaussian Markov random field (GMRF) models with adjacency-based neighbourhood weight matrix, commonly known as neighbourhood-based GMRF models, have been the mainstream approach to spatial smoothing in Bayesian disease mapping. In the present paper, we propose a conditionally specified Gaussian random field (GRF) model with a similarity-based non-spatial weight matrix to facilitate non-spatial smoothing in Bayesian disease mapping. The model, named similarity-based GRF, is motivated for modelling disease mapping data in situations where the underlying small area relative risks and the associated det...
Source: Statistical Methods in Medical Research - August 25, 2016 Category: Statistics Authors: Baptista, H., Mendes, J. M., MacNab, Y. C., Xavier, M., Caldas-de-Almeida, J. Tags: Special Issue Articles Source Type: research
Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer
Conclusions Cleaved caspase-3 immunoexpression showed differences in oral SCCs and PMDs and demonstrated a distinct role of apoptosis in carcinogenesis of intraoral and lower lip cancer. In future, the expression of cleaved caspase-3 with other target molecules in oral cancer may be helpful in delineating the prognosis and treatment of these tumors. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - August 23, 2016 Category: Dentistry Source Type: research
Two ‐Piece Extraoral Prosthetic Rehabilitation to a Perineural Invasion Lip Cancer
Journal of Prosthodontics,Volume 27, Issue 3, Page 306-310, March 2018. (Source: Journal of Prosthodontics)
Source: Journal of Prosthodontics - August 12, 2016 Category: Dentistry Source Type: research
