Mechanical and optical properties of conventional restorative glass-ionomer cements - a systematic review
Conclusions It was not possible to compare the results for the mechanical and optical properties of conventional restorative GICs due to the lack of standardization of studies. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Temporomandibular joint disc displacement with reduction: a review of mechanisms and clinical presentation
Abstract Disc displacement with reduction (DDWR) is one of the most common intra-articular disorders of the temporomandibular joint (TMJ). Factors related to the etiology, progression and treatment of such condition is still a subject of discussion. This literature review aimed to address etiology, development, related factors, diagnosis, natural course, and treatment of DDWR. A non-systematic search was conducted within PubMed, Scopus, SciELO, Medline, LILACS and Science Direct using the Medical Subjective Headings (MeSH) terms “ temporomandibular disorders ” , “ temporomandibular joint ” , “...
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Retinoic acid increases the effect of bone morphogenetic protein type 2 on osteogenic differentiation of human adipose-derived stem cells
Abstract Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. Objective Considering the different results of RA on osteogenesis and its possible use to substitute/potency BMP-2 effects, this study evaluated the outcomes of BMP-2, RA, and BMP-2+RA treatments on in vitro osteogenic differentiation of human adipose-derived stem cells (ASCs) and the signaling pathway(s) involved. Material and Methods ASCs were treated every other day with basic osteog...
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1β, IL-10, RANK, OPG, MMP-2, TGF-β and TNF-α: follow-up over 5 years
Conclusions The salivary concentration of TNF- α was increased in individuals with worse periodontal and peri-implant clinical condition and in those with a higher incidence of peri-implantitis, especially in the GNTP group. Longitudinal studies in larger populations are needed to confirm these findings and elucidate the role of this biomarker in peri-implant disease. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Cytotoxicity of intracanal dressings on apical papilla cells differ upon activation with E. faecalis LTA
Abstract Objective The aim of this study was to investigate the cytotoxic effects of modified triple antibiotic paste and an experimental composition using calcium hydroxide on lipoteichoic acid (LTA)-primed apical papilla cells (APC). Material and Methods Human APC were tested for in vitro cytotoxicity of modified Triple Antibiotic Paste (mTAP – Ciprofloxacin, Metronidazole and Cefaclor at 1:1:1) and of a paste of Ciprofloxacin, Metronidazole and Calcium hydroxide (CMC – 1:1:2) and modified CMC (mCMC – 2:2:1) by using MTT assay. The substances were reconstituted in DMEM at 1,000 µg/mL and ¼ ...
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Fluoride release and uptake in enhanced bioactivity glass ionomer cement (“glass carbomer™”) compared with conventional and resin-modified glass ionomer cements
Conclusions Glass carbomer resembles glass ionomer cements in its fluoride uptake behavior but differs when considering that its fluoride uptake does not lead to increased fluoride release. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model
Conclusions This treatment decreased neutrophil and macrophage migration, decreased the inflammatory response, and decreased bone loss in rats with ligature-induced periodontitis. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Resin-modified glass ionomer containing calcium glycerophosphate: physico-mechanical properties and enamel demineralization
This study evaluated the effect of adding calcium glycerophosphate (CaGP) to resin-modified glass ionomer cement (RMGIC) on the physico-mechanical properties, ion release, and enamel demineralization. Material and Methods: Specimens were fabricated for each experimental group: RMGIC without CaGP (Control), RMGIC with 1, 3 and 9% CaGP. To determine the release of fluoride (F), calcium (Ca) and phosphorus (P), six specimens were immersed in demineralization and remineralization solutions for 15 days. In another experimental trial, the following physico-mechanical properties were evaluated at time intervals of 1 and 7 days af...
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Whitening toothpaste containing activated charcoal, blue covarine, hydrogen peroxide or microbeads: which one is the most effective?
This study compared the whitening performance of toothpastes with different whitening technologies after initial and continued use. Material and Methods: Ninety bovine incisors were stained using a concentrated solution of black tea. They were randomly distributed into 6 groups, according to the toothpaste whitening technology: activated charcoal (B&W), blue covarine (WAD), hydrogen peroxide (LWA), microbeads (Oral B 3D White Perfection – 3DW) and optimized abrasives (XW4D). They were compared to a traditional toothpaste without a whitening agent (TA – control). Specimens underwent a brushing machine with c...
Source: Journal of Applied Oral Science - January 15, 2019 Category: Dentistry Source Type: research

Evaluating clinical and laboratory effects of ozone in non-surgical periodontal treatment: a randomized controlled trial
Conclusion: The findings of this study indicate that SRP plus gaseous ozone versus SRP alone does not correlate to a significant improvement in periodontal recovery. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - January 15, 2019 Category: Dentistry Source Type: research

Influence of mandibular and palatal intraoral appliances on erosion in situ study outcome
Abstract The standardization of in situ protocols for dental erosion is important to enable comparison between studies. Objective: Thus, the objectives of this study were to evaluate the influence of the location of in situ intraoral appliance (mandibular X palatal) on the extent of enamel loss induced by erosive challenges and to evaluate the comfort of the appliances. Material and Methods: One hundred and sixty bovine enamel blocks were selected according to their initial surface hardness and randomly divided into two groups: GI - palatal appliance and GII - mandibular appliance. Twenty volunteers wore simultaneously one...
Source: Journal of Applied Oral Science - January 15, 2019 Category: Dentistry Source Type: research

Assessment of anesthetic properties and pain during needleless jet injection anesthesia: a randomized clinical trial
This study aimed to measure the degree of pain during administration of anesthesia and determine the latency time and duration of pulpal anesthesia using two anesthetic methods in the maxilla. Materials and Methods: A randomized, single-blind, split-mouth clinical trial was conducted with 41 volunteers who required class I restorations in the maxillary first molars. Local anesthesia was administered with a needleless jet injection system (experimental group) or with a carpule syringe (control) using a 30-gauge short needle. The method of anesthesia and laterality of the maxilla were randomized. A pulp electric tester measu...
Source: Journal of Applied Oral Science - January 15, 2019 Category: Dentistry Source Type: research

BK virus salivary shedding and viremia in renal transplant recipients
Conclusion: The results of this study suggested that, although saliva excretes more BKPyV than blood, there is no reliable correlation between salivary shedding and blood viremia, showing two independent compartments of viral replication. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - January 15, 2019 Category: Dentistry Source Type: research

Effects of dodecacalcium hepta-aluminate content on the setting time, compressive strength, alkalinity, and cytocompatibility of tricalcium silicate cement
This study aimed to investigate the effects of dodecacalcium hepta-aluminate (C12A7) content on some physicochemical properties and cytocompatibility of tricalcium silicate (C3S) cement using human dental pulp cells (hDPCs). Material and Methods High purity C3S cement was manufactured by a solid phase method. C12A7 was mixed with the cement in proportions of 0, 5, 8, and 10 wt% (C12A7-0, − 5, − 8, and − 10, respectively). Physicochemical properties including initial setting time, compressive strength, and alkalinity were evaluated. Cytocompatibility was assessed with cell viability tests and cell number c...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Distribution of depression, somatization and pain-related impairment in patients with chronic temporomandibular disorders
Conclusion patients with TMD frequently present an emotional profile with low disability, high intensity pain-related impairment, and high to moderate levels of somatization and depression. Therefore, given the importance of psychosocial issues at the prognostic level, it is recommended that clinical trials on TMD treatment include an evaluation of patients ’ psychosocial profiles. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Comparison between static and semi-dynamic models for microcosm biofilm formation on dentin
This study compared the performance of two kinds of models (static and semi-dynamic) on the biofilm formation and the development of dentin carious lesions. Material and Methods In both models, biofilm was produced using inoculum from pooled human saliva mixed with McBain saliva for the first 8 h (5% CO2 and 37 °C). Afterwards, for the static model, the samples were placed in 24-wells microplate containing McBain saliva with 0.2% sucrose, which was replaced at 24 h. In the semi-dynamic model, the samples were submitted to artificial mouth system with continuous flow of McBain saliva with 0.2% sucrose (0.1 5 ml/min, 37&...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Influence of surfactants addition on the properties of calcium hypochlorite solutions
Conclusion Surfactant addition to 2.5% Ca(OCl)2 has shown acceptable outcomes for pH, free chlorine content, surface tension, contact angle, pulp dis solution and antimicrobial activity. Furthermore, the addition of 0.2% Cet showed better results for all tested properties. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Effect of ProRoot MTA® and Biodentine® on osteoclastic differentiation and activity of mouse bone marrow macrophages
Abstract Objectives This investigation aimed to assess the differentiation inhibitory effects of ProRoot MTA ® (PMTA) and Biodentine® (BIOD) on osteoclasts originated from murine bone marrow macrophages (BMMs) and compare these effects with those of alendronate (ALD). Materials and Methods Mouse BMMs were cultured to differentiate into osteoclasts with macrophage colony-stimulating factor and receptor a ctivator of NF- κ B (RANKL), treated with lipopolysaccharide. After application with PMTA, BIOD, or ALD, cell toxicities were examined using WST-1 assay kit, and RANKL-induced osteoclast differentiation and ac...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Shrinkage stress and elastic modulus assessment of bulk-fill composites
Conclusions: Bulk-fill resin composites presented equal to lower shrinkage stress generation when compared to conventional composites, especially when bigger increments were evaluated. Bulk-fill composites showed a wide range of elastic modulus values, but usually similar to “ regular ” composites. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
Conclusion EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, prese rved bond strength and adhesive interface, and reduced cytotoxicity. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Comparison of in vitro erosion protocols in bovine teeth to simulate natural erosion lesion: analysis of mechanical properties and surface gloss
Abstract Objective The aim of this study was to compare two in vitro erosion protocols, in which one simulates in vivo conditions experienced by patients with gastroesophageal disorders or bulimia (HCl-pepsin protocol), and the other simulates the diet of an individual who consumes a high volume of erosive beverages (citric acid protocol). In addition, the mechanical properties and surface gloss of eroded human dentin were compared with those of sound human dentin. Materials and Methods Blocks of cervical dentin were used: sound human dentin (n=10), human dentin with erosive lesions (n=10), and bovine dentin (n=30). Twenty...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Effect of radiant exposure and UV accelerated aging on physico-chemical and mechanical properties of composite resins
The objective of this study was to evaluate the effect of radiant exposure and UV accelerated aging on the physico-chemical and mechanical properties of micro-hybrid and nanofilled composite resins. Material and Methods: A nanofilled (Filtek Supreme; 3M ESPE) and a micro-hybrid composite resin (Filtek Z250; 3M ESPE) were investigated under different radiant exposures (3.75, 9, and 24 J/cm2) and UV accelerated aging protocols (0, 500, 1000, and 1500 aging hours). The degree of conversion (DC), flexural strength (FS), modulus (M), water sorption (WS), and solubility (WL) were evaluated. The results obtained were analyzed usi...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Efficacy of sonic and ultrasonic irrigation devices in the removal of debris from canal irregularities in artificial root canals
Abstract Objective To evaluate the efficacy of different sonic and ultrasonic devices in the elimination of debris from canal irregularities in artificial root canals. Materials and Methods A resin model of a transparent radicular canal filled with dentin debris was used. Five groups were tested, namely: Group 1 – ultrasonic insert 15.02; Group 2 – ultrasonic insert 25/25 IRRI K; Group 3 – ultrasonic insert 25/25 IRRI S; Group 4 – sonic insert 20/28 Eddy on a vibrating sonic air-scaler handpiece; Group 5 – 20.02 K-file inserted on a Safety M4 handpiece. Two different irrigants (5% sodium hypoc...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Evaluation of pain perception during orthodontic debonding of metallic brackets with four different techniques
Abstract Objective The aim of this study was to evaluate patients ’ pain levels during four different debonding procedures. The null hypothesis was that the pain perception of the patients undergoing four different debonding applications was not statistically significant different. Material and Methods One hundred and twenty orthodontic patients who underwent orthodontic debonding were included in this study. The patients were randomly divided into 4 groups according to technique used in the patients. Debonding groups were as follows: Group 1) Conventional debonding group, Group 2) Medication group (acetaminophen was...
Source: Journal of Applied Oral Science - January 7, 2019 Category: Dentistry Source Type: research

Development and characterization of a novel bulk-fill elastomeric temporary restorative composite
Conclusions: The present findings suggest that the physical, mechanical and biological properties of the experimental TFMs with ZM are comparable with the properties of the commercial reference. However, some properties were improved, such as lower microleakage and water sorption, and higher ultimate tensile strength values. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Effect of diode laser irradiation on the bond strength of polymerized non-simplified adhesive systems after 12 months of water storage
Abstract Objectives: The aim of this in vitro study was to evaluate the bonding strength of non-simplified dentin bonding systems (DBS) to dentin irradiated with a diode laser (970 nm) immediately and after 12 months of water storage following either primer or bond application. Material and methods: The experimental design included three different factors: DBS type [AdperTM Scotchbond Multipurpose (MP) and Clearfil ™ SE Bond (CSE)], irradiation [without irradiation - control (C), irradiation after primer application (AP), and irradiation after bond application (AB)], and time [initial (I) and after 12 months of water...
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Proteomic analysis of the acquired enamel pellicle formed on human and bovine tooth: a study using the Bauru in situ pellicle model (BISPM)
Conclusion: These results demonstrate that the proteins typically found in the AEP appeared in both groups, regardless the substrate. The BISPM revealed to be a good device to be used in studies involving proteomic analysis of the AEP. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Surface and vertical dimensional changes of mineral trioxide aggregate and biodentine in different environmental conditions
This study investigated surface alterations of calcium silicate-based cements after exposure to different environments. Material and Methods: Forty-eight cylindrical cavities were prepared on root surfaces. The cavities were filled using ProRoot MTA or Biodentine and assigned to four subgroups (n=6): dry, wet, acidic, and blood. Surface topographies were evaluated using an optical profilometer for 28 days, and the roughness of the material surfaces was quantified. Vertical dimensional change was measured by determining the height difference between the material surface and the flat tooth surface. Data were compared with a ...
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Effect of fluoride application during radiotherapy on enamel demineralization
Abstract Radiation-related caries are one the most undesired reactions manifested during or after head and neck radiotherapy. Fluoride application is an important strategy to reduce demineralization and enhance remineralizaton. Objective: To evaluate the effect of the topical application of fluoride during irradiation on dental enamel demineralization. Material and Methods: Thirty molars were randomly divided into three groups: Non-irradiated (NI), Irradiated (I), Irradiated with fluoride (IF). Each group was subdivided according to the presence or absence of pH-cycling (n=5). In the irradiated groups, the teeth received 7...
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Inhibitory effect of reduced graphene oxide-silver nanocomposite on progression of artificial enamel caries
Conclusion: As a novel composite material, rGO/Ag can be a promising antibacterial agent for caries prevention. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Effect of topical ozonetherapy on gingival wound healing in pigs: histological and immuno-histochemical analysis
Conclusion: The topical application of ozone gas could be effective in the early stages of wound healing by increasing the amount of VEGF expression. Clinical Relevance: Topical application of ozone gas may be effective in the early stages of oral wound healing. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Effects of in-office bleaching agent combined with different desensitizing agents on enamel
Abstract Objective: To analyze color change, microhardness and chemical composition of enamel bleached with in-office bleaching agent with different desensitizing application protocols. Materials and Methods: One hundred and seventeen polished anterior human enamel surfaces were obtained and randomly divided into nine groups (n = 13). After recording initial color, microhardness and chemical composition, the bleaching treatments were performed as G1: Signal Professional White Now POWDER&LIQUID FAST 38% Hydrogen peroxide(S); G2: S+Flor Opal/0.5% fluoride ion(F); G3: S+GC Tooth Mousse/Casein Phosphopeptide-Amorphous Calc...
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

The link between ankylosing spondylitis and oral health conditions: two nested case-control studies using data of the UK Biobank
Conclusion: Self-reported and clinically diagnosed AS populations have increased risk of reporting oral ulcers. Further investigations are required to assess the link between a specific type of oral condition and AS. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys
Conclusion: Based on this methodology, it may be concluded that gingival overgrowths induced by cyclosporin, nifedipine and phenytoin are not associated with neither myofibroblast transdifferentiation, proliferation nor apoptosis of gingival connective cells in monkeys. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Correlation of salivary immunoglobulin A with Body Mass Index and fat percentage in overweight/obese children
This study aimed to determine correlations and associations between gingival inflammation (Simplified Oral Hygiene Index, and Gingival Index), salivary immunoglobulin A (s-IgA), and salivary parameters (salivary flow and osmolality) in normal-weight and overweight/obese children. Material and Methods: Ninety-one children, aged 6 to 12 years old (8.6 ±1.9 years), were divided into two groups according to their body mass index (BMI), circumferences, skinfold measurements and body fat percentage: normal- weight group (NWG; n =50) and overweight/obese group (OG; n =41). A calibrated examiner performed the clinical exami...
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Stanozolol promotes osteogenic gene expression and apposition of bone mineral in vitro
Conclusions: This study provided encouraging results, showing ST promoted the osteogenic commitment of SaOS-2 cells. Further studies are required to validate these data in primary osteoblasts and to investigate ST molecular pathway of action. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Surface morphology and mechanical properties of conventional and self-adhesive resin cements after aqueous aging
This study aimed at evaluating and comparing the surface morphology and mechanical property of conventional and self-adhesive resin cement after aqueous aging. Materials and Methods: Disc-shaped specimens of 3 conventional (C1: Multilink N, C2: Duolink, C3: Nexus 3) and 3 self-adhesive (S1: Multilink Speed, S2: Biscem, S3: Maxcem) types of resin cements were subjected to irradiation. After 24 h, the Knoop microhardness of each resin cement was evaluated. The specimens were immersed separately in distilled water and maintained at 37 °C. A total of 5 specimens of each resin cement were collected at the following time int...
Source: Journal of Applied Oral Science - December 12, 2018 Category: Dentistry Source Type: research

Clinical wear of approximal glass ionomer restorations protected with a nanofilled self-adhesive light-cured protective coating
Conclusion: These results suggest that the application of a NPC has a protective effect on the clinical wear of approximal GIC restorations in primary teeth. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

The role of potassium channels in the endothelial dysfunction induced by periodontitis
Conclusions: Periodontitis induces impairment in endothelial-dependent relaxation; this impairment recovers, even in the presence of periodontitis. The recovery is mediated by the activation of endothelial calcium-activated potassium channels in ligature animals. Although important for maintenance of vascular homeostasis, this effect could mask the lack of NO, which has other beneficial properties. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

Pulp analysis of teeth submitted to different types of forces: a histological study in rats
Conclusions: Pulp tissue alterations resulting from ITM were limited to hemodynamic events, without progressing to irreversible degeneration, regardless of the type of force applied. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

Effects of experimental bleaching agents on the mineral content of sound and demineralized enamels
Abstract High concentrations of hydrogen peroxide can cause adverse effects on composition and structure of teeth. However, the addition of calcium and fluoride in bleaching agents may reduce enamel demineralization. Objective: To evaluate chemical changes of sound and demineralized enamels submitted to high concentrations of hydrogen peroxide containing fluoride (F) or calcium (Ca). Material and Methods: Enamel blocks of bovine incisors with standard dimensions were obtained and half of them were submitted to pH-cycling to promote initial enamel caries lesions. Sound and demineralized enamel samples were divided into (n=1...
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

Quorum sensing LuxS/autoinducer-2 inhibits Enterococcus faecalis biofilm formation ability
Abstract Objective: To investigate the relation between biofilm formation ability and quorum sensing gene LuxS/AI-2. Materials and Methods: Enterococcus faecalis (E. faecalis) standard strain ATCC 29212 was used in the study. Long flanking homology polymerase chain reaction method was used to build the LuxS gene knockout strain. Sequential culture turbidity measurement and CFU counting were used to assess the proliferation ability of E. faecalis after the depletion of LuxS. 96-well plate assay was used to quantify the biofilm formation ability; CLSM was used to observe the attached bacteria areas, while scanning electron m...
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

IFN-γR2 is strongly expressed on endothelial cells of gingival tissues from patients with chronic periodontitis
Abstract Chronic periodontitis (CP) is characterized by gingival inflammation and bone destruction. It has been reported that interferon-gamma (IFN- γ ) levels are high in CP patients; however, the IFN- γ receptor (IFN- γ R) has not been studied in gingival tissue from these patients. Objective: To evaluate IFN- γ levels and IFN- γ R expression in gingival tissue biopsies from chronic periodontitis patients compared with healthy subjects (HS). Material and Methods: Gingival tissues were obtained from all study subjects, CP (n = 18) and healthy subjects (HS) (n = 12). A tissue section of each s...
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

Volumetric reconstruction and determination of minimum crosssectional area of the pharynx in patients with cleft lip and palate: comparison between two different softwares
Conclusion: Measurements of volume and mCSA are statistically similar between applications. Therefore, open-source applications may be a viable option to assess upper airway dimensions using CBCT exams. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

One-year prospective clinical study comparing patient satisfaction and masticatory performance of mandibular overdentures supported by one versus two implants
Abstract There is a lack of clinical evidence on mandibular overdentures (MOD) supported by a single implant. Objective: To compare patient satisfaction and masticatory performance in MOD supported by one versus two implants in a two-group parallel randomized clinical trial. Material and Methods: Twenty-one patients wearing new maxillary and mandibular complete dentures (CDs) were randomly divided to receive one (GI, n = 11) or two (GII, n = 10) implants in the mandibular arch. Four months after implant placement, o-ring abutments were installed in the implants, and matrix attachments were placed in the lower complete dent...
Source: Journal of Applied Oral Science - October 4, 2018 Category: Dentistry Source Type: research

Cyclic flexural fatigue resistance of NiTi Controlled Memory and Blue Technology instruments after torsional preloading
Abstract Objective The aim of this study was to evaluate the influence of torsional preloading on the cyclic flexural fatigue resistance of thermally treated NiTi instruments. Material and Methods Ten new instruments New Hyflex CM (HF 30.06; Coltene/Whaladent Inc.), Typhoon CM (TYP 30.06; Clinician's Choice Dental Products) and Vortex Blue (VB 30.06; Dentsply Tulsa Dental) were chosen, based on geometry and specific characteristics of the manufacturing process. The new instruments of each system were tested in a bench device to determine their fatigue resistance through mean value of number of cycles to failure (Nf) (Contr...
Source: Journal of Applied Oral Science - August 21, 2018 Category: Dentistry Source Type: research

Effect of cavity preparation design and ceramic type on the stress distribution, strain and fracture resistance of CAD/CAM onlays in molars
This study aimed to evaluate the effect of the cavity preparation and ceramic type on the stress distribution, tooth strain, fracture resistance and fracture mode of human molar teeth restored with onlays. Material and Methods Forty-eight molars were divided into four groups (n=12) with assorted combinations of two study factors: BL- conventional onlay preparation with boxes made from leucite ceramic (IPS-Empress CAD, Ivoclar Vivadent); NBL- conservative onlay preparation without boxes made from leucite ceramic; BD- conventional onlay preparation with boxes made from lithium disilicate glass ceramic (IPS e.max CAD, Ivoclar...
Source: Journal of Applied Oral Science - August 21, 2018 Category: Dentistry Source Type: research

Evaluation of physical-mechanical properties, antibacterial effect, and cytotoxicity of temporary restorative materials
The objective of this study was to compare selective physical-mechanical properties, antibacterial effects and cytotoxicity of seven temporary restorative materials (TRM): five resin-based materials [Bioplic (B), Fill Magic Tempo (FM), Fermit inlay (F), Luxatemp LC (L) and Revotek LC (R)], and zinc oxide-eugenol cement (IRM) and glass ionomer cement (GIC) as the controls. Material and methods The physical-mechanical properties were evaluated by determining microleakage (ML), ultimate tensile strength (UTS) and Shore D hardness (SDH). In addition, the polymerization rate (Pr-1), depth of cure (DC), water sorption and solubi...
Source: Journal of Applied Oral Science - August 21, 2018 Category: Dentistry Source Type: research

Relationship between phonological working memory, metacognitive skills and reading comprehension in children with learning disabilities
Conclusion children with learning disabilities presented deficits in phonological working memory and use of metacognitive strategies. The positive and effective correlation between the abilities analyzed suggests that failure in the phonological working memory and use of metacognitive strategies interfere with reading comprehension. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - August 21, 2018 Category: Dentistry Source Type: research

Effect of non-surgical periodontal therapy on the degree of gingival inflammation and stress markers related to pregnancy
Abstract Objectives The purpose of this study was to determine the impact of nonsurgical periodontal therapy considering the salivary stress-related hormone and cytokine levels in the gingival crevicular fluid (GCF) on pregnant and nonpregnant women. Material and Methods Thirty non-pregnant (control group) and 30 pregnant women (test group) that met the study inclusion criteria were chosen. Only participants with gingivitis were included. Clinical data and samples of GCF and saliva were collected at baseline and after periodontal therapy. The levels of interleukin-1 beta ( Κ -1 β ) and IL-10, and concentration o...
Source: Journal of Applied Oral Science - July 23, 2018 Category: Dentistry Source Type: research