The prevalence of novel periodontal pathogens and bacterial complexes in Stage II generalized periodontitis based on 16S rRNA next generation sequencing
Conclusion: The bacterial species corresponding to the disease-related orange complex and novel periodontal pathogens are predominant in Stage II generalized periodontitis. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - May 17, 2021 Category: Dentistry Source Type: research
Recombinant human insulin-like growth factor-1 promotes osteoclast formation and accelerates orthodontic tooth movement in rats
Conclusion: Our study has showed that rhIGF-1 could stimulate the formation of osteoclasts in the periodontal ligament, and accelerate bone remodeling and orthodontic tooth movement. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - May 14, 2021 Category: Dentistry Source Type: research
Physicochemical properties and biological effects of quaternary ammonium methacrylates in an experimental adhesive resin for bonding orthodontic brackets
Conclusion: Both adhesives with QAMs showed a significant reduction in bacterial metabolic activity, but this effect decreased after water aging. Lower cell viability was observed for the group with the longer alkyl chain-QAM, without significant differences for the bonding ability and degree of conversion. The addition of QAMs in adhesives may affect the keratinocytes viability, and the aging effects maybe decrease the bacterial activity of QAM-doped materials. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - May 4, 2021 Category: Dentistry Source Type: research
Physicochemical properties and effect of bioceramic root canal filling for primary teeth on osteoblast biology
Conclusions Bio-CP showed adequate physicochemical properties, cytocompatibility and potential to induce mineralisation. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - May 4, 2021 Category: Dentistry Source Type: research
Prevalence of hyposalivation and associated factors in survivors of head and neck cancer treated with radiotherapy
Conclusion: Hyposalivation is a highly prevalence late-onset side effect of radiotherapy in patients treated for head and neck cancer, with a greater chance of occurrence among those who received higher doses of radiation and those who ended therapy less than 22 months before our study . Concomitant chemotherapy and radiotherapy does not seem to increase the chances of hyposalivation compared to radiotherapy alone. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 19, 2021 Category: Dentistry Source Type: research
A novel acrylic resin palatal device contaminated with Candida albicans biofilm for denture stomatitis induction in Wistar rats
Conclusions This acrylic resin palatal device was designed to be similar to the clinical situation of contaminated prostheses, with easy manufacturing and handling, effective stabilization, and satisfactory contamination. Thus, the acrylic device can be a valuable tool in the development of denture stomatitis in rats. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 19, 2021 Category: Dentistry Source Type: research
The effect of reduced glutathione on the toxicity of silver diamine fluoride in rat pulpal cells
Conclusion SDF severely disturbed the viability, mineralization-ability, and morphology of pulpal-like cells, while controlled concentrations of GSH had a short-term protective effect against SDF-induced damage. GSH showed an inhibitory effect on SDF-induced dentinal deposit formation. Further research is warranted to evaluate the effect of GSH on caries-arresting, anti-hypersensitivity, and antibacterial functions of SDF. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 19, 2021 Category: Dentistry Source Type: research
Root canal retreatment: a retrospective investigation using regression and data mining methods for the prediction of technical quality and periapical healing
Conclusion Frequent patterns and factors affecting technical outcomes of endodontic retreatment included root canal morphological features and its alterations resulting from primary endodontic treatment. Healing outcomes were mainly associated with the extent of apical periodontitis pathological damages in dental and periapical tissues. To determine treatment predictability, we suggest patterns including clinical and radiographic features of apical periodontitis and technical quality of primary endodontic treatment. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 19, 2021 Category: Dentistry Source Type: research
Dental and maxillomandibular incidental findings in panoramic radiography among individuals with mucopolysaccharidosis: a cross-sectional study
Conclusion The presence of specific oral manifestations is more common in MPS individuals than non-MPS individuals. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 14, 2021 Category: Dentistry Source Type: research
Effect of different low-level intensity laser therapy (LLLT) irradiation protocols on the osseointegration of implants placed in grafted areas
Conclusion LLLT performed on implants placed in grafted areas enhances the osseointegration process. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 14, 2021 Category: Dentistry Source Type: research
MicroRNAs: emerging players in apical periodontitis
Abstract Apical periodontitis is an inflammatory disorder of periradicular tissues developed from endodontic infections. Understanding its pathophysiology and the underlying molecular mechanisms is key to the advancement of endodontics. MicroRNAs (miRNAs), a group of evolutionarily conserved small non-coding RNAs, may be phenotypically and functionally associated with the pathogenesis of apical periodontitis. Several studies have focused on the role of miRNAs in the pulp and periradicular biology, and they have demonstrated their essential functions, such as initiating odontogenic differentiation and promoting pro- or anti...
Source: Journal of Applied Oral Science - April 14, 2021 Category: Dentistry Source Type: research
Comparison of tooth movement and biological response resulting from different force magnitudes combined with osteoperforation in rabbits
Conclusion Osteoperforation could accelerate orthodontic tooth movement rate in rabbits. Fast osteoperforation-assisted tooth movement in rabbits was achieve with light 50 g traction. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 3, 2021 Category: Dentistry Source Type: research
Dentinal tubule occlusion using Er:YAG Laser: an in vitro study
Conclusion Therefore, 0.5 W (167 J/cm2) is a suitable parameter for Er:YAG laser to occlude DTs, and it is safe to the pulp tissue. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 3, 2021 Category: Dentistry Source Type: research
Fcγ receptors on aging neutrophils
Conclusions Our results suggest that, in humans, the overall pattern of Fc γ R expression and integrin CD11b are altered during aging and immunosenescence might contribute to age-related infection. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - March 31, 2021 Category: Dentistry Source Type: research
Association of Nd:YAG laser and calcium-phosphate desensitizing pastes on dentin permeability and tubule occlusion
Conclusion All treatments effectively reduced dentin permeability and promoted tubule occlusion after application. Combining Nd YAG laser with calcium-phosphate pastes did not improve the laser effect. After erosive-abrasive challenges, treatments presented no differences when compared to the control. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - March 31, 2021 Category: Dentistry Source Type: research
