Cancer risks in a population-based study of agricultural workers: results from the Taiwan ’s Farmers and Health Cohort study
Conclusions This study provides farmer cancer patterns and risk, adding to the evidence that farmers are at increased risk of certain types of cancer, especially for hematological cancers. As exposure varies by farm operation type, individual farmer exposure may vary widely. Further understanding of the complex relationship between occupational exposure, environmental factors, and lifestyle factors is needed. by Chen W-L, Lin G-L, Lin Y-J, Su T-Y, Wang C-C, Wu W-T. doi:10.5271/sjweh.4104 (Source: Scandinavian Journal of Work, Environment and Health)
Source: Scandinavian Journal of Work, Environment and Health - July 14, 2023 Category: Occupational Health Tags: Original article Source Type: research

Occupational variation in the incidence of lip cancer in the Nordic countries
CONCLUSIONS: The incidence of lip cancer varies widely between outdoor and indoor occupations. Occupations involving outdoor activity and exposure to sunlight show the most elevated SIRs.PMID:37337140 | DOI:10.1080/0284186X.2023.2224053 (Source: Acta Oncologica)
Source: Acta Oncologica - June 19, 2023 Category: Cancer & Oncology Authors: Rayan Mroueh Timo Carp én Antti M äkitie Johnni Hansen Sanna Heikkinen Elsebeth Lynge Jan Ivar Martinsen Jenny Selander Ingrid Sivesind Mehlum J óhanna Eyrún Torfadottir Tuula Salo Eero Pukkala Source Type: research

Clinicopathological study of lip cancer - a retrospective analysis of 274 cases
The goal of this study was to describe 274 cases of lip cancer and examine their clinicopathological characteristics. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 15, 2023 Category: ENT & OMF Authors: Lauren Frenzel SCHUCH, F ábio Muradás GIRARDI, Manoela Domingues MARTINS Source Type: research

Early diagnosis of lip cancer: a case report
A 53-year-old white male complained of a tongue alteration, noted by the dentist. On clinical examination, besides the lingual lesion, other changes were also observed: multiple red and blackened papules on the facial skin and atrophy of the lower lip, with loss of the interface between the skin and the labial mucosa, along with superficial and color changes, suggestive of actinic lesions (keratosis and cheilitis). Incisional biopsies were performed, and the histopathological reports were of the presence of epithelial atypia with the absence of malignancy in the tongue, compatible with microinvasive squamous cell carcinoma...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 15, 2023 Category: ENT & OMF Authors: Luana Clementino CORDEIRO, Ednaldo Jos é da SILVA, Vania do Carmo RODRIGUES, Luisa AGUIRRE Buexm, Adriana Terezinha Neves NOVELLINO Alves, Ana Flávia SCHUELER de Assumpção Leite, Simone de Queiroz Chaves LOURENÇO Source Type: research

Simple lip reconstruction technique for middle-sized defects in lower lip cancer — Bilateral oblique mucosal V-Y advancement flap
We present the case of a 76-year-old woman with severe dementia, referred to our institute for a tumor on her lower lip. She was diagnosed with lip squamous cell carcinoma (cT2N0M0). The tumor measured 25  × 20 mm. It was resected with a surgical safety margin of 6 mm. Bilateral triangular flaps were fashioned obliquely on the rear lateral side of the defect extending from the labial to the buccal mucosa and used to repair the defect. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - June 12, 2023 Category: ENT & OMF Authors: Shunsuke Miyamoto, Takashi Matsuki, Taku Yamashita Tags: Case Report Source Type: research

High-dose-rate brachytherapy at 3 Gy per fraction for lip carcinoma: Treatment outcomes and toxicity at 5-years
Low-dose-rate brachytherapy (LDR-BT) is a well-established treatment for lip cancer. High-dose-rate (HDR)-BT is a promising alternative to LDR-BT, but data are limited. In this context, we retrospectively evaluated treatment outcomes in a series of patients who underwent HDR-BT for lip carcinoma between 2003 and 2021. (Source: Brachytherapy)
Source: Brachytherapy - April 2, 2023 Category: Cancer & Oncology Authors: Lubo š Tuček, Igor Sirák, Miroslav Hodek, Linda Kašaová, Jakub Grepl, Petr Paluska, Denisa Pohanková, Libor Hruška, Milan Vošmik, Jiří Petera Tags: Head and Neck Source Type: research

Cancers, Vol. 15, Pages 1478: Tumor Microenvironment and Immune Response in Lip Cancer
We examined the TIL and tertiary lymphoid structure (TLS) density in the invading front and inner tumor stroma, and the lymphocyte subpopulation (CD8, CD4, FOXP3) density in 60 squamous cell carcinomas of the lip. Analysis was performed in parallel with markers of hypoxia (hypoxia-inducible factor (HIF1α), lactate dehydrogenase (LDHA)) and angiogenesis. Low TIL density in the invading tumor front was related with larger tumor size (p = 0.05), deep invasion (p = 0.01), high smooth-muscle actin (SMA) expression (p = 0.01), and high HIF1α and LDH5 expression (p = 0.04). FOXP3+ TILs infiltration and...
Source: Cancers - February 25, 2023 Category: Cancer & Oncology Authors: Anastasia G. Gkegka Michael I. Koukourakis Maria Lambropoulou Alexandra Giatromanolaki Tags: Article Source Type: research

Interstitial Brachytherapy for Lip Cancer: Technical Aspects to Individualize Treatment Approach and Optimize Outcomes
In this report, we discuss patient selection criteria, procedural details, and dosimetric considerations for performing IBT for cancers of the lip. Catheters are inserted across the length of tumor entering and exiting approximately 5 mm beyond the palpable tumor extent. A custom mouthpiece is fabricated to facilitate normal tissue sparing. Patients undergo CT imaging, the gross tumor volume (GTV) is contoured based on physical exam and CT findings, and an individualized BT plan is generated with goals of achieving GTV D90% ≥ 90% and minimizing V150%. Ten patients with primary (n=8) or recurrent (n=2) cancers of the lip ...
Source: Cancer Control - January 28, 2023 Category: Cancer & Oncology Authors: Emily C Merfeld Matthew E Witek David M Francis Adam R Burr Charles R Wallace Aleksandra Kuczmarska-Haas Narottam Lamichhane Randall J Kimple Tiffany A Glazer Aaron M Wieland Timothy M McCulloch Gregory K Hartig Paul M Harari Source Type: research

Custom-made radiotherapy prosthesis for external and internal radiotherapy in a patient with lip cancer
J Oral Sci. 2022 Dec 16. doi: 10.2334/josnusd.22-0306. Online ahead of print.NO ABSTRACTPMID:36529514 | DOI:10.2334/josnusd.22-0306 (Source: Journal of oral science)
Source: Journal of oral science - December 18, 2022 Category: Dentistry Authors: Jiangyu Wang Mai Murase Cheewin Towithelertkul Hiroko Tani Yuka I Sumita Source Type: research

Treatment outcomes of squamous cell carcinoma of the lip: A retrospective study
Oncol Lett. 2022 Nov 14;25(1):8. doi: 10.3892/ol.2022.13594. eCollection 2023 Jan.ABSTRACTOral and lip cancer is the most common type of cancer among males in India. Early stage tumours of the lip (stages I and II) are treated with single modality treatment, using either radiotherapy [external beam radiotherapy (EBRT) or brachytherapy] or surgery. Locally advanced tumours (stages III and IVa) are treated with surgery followed by adjuvant treatment. The aim of the present study was to retrospectively evaluate the clinical profile and treatment outcomes of patients with squamous cell carcinoma of the lip who were treated wit...
Source: Oncology Letters - December 8, 2022 Category: Cancer & Oncology Authors: Geethu Babu Rejnish Ravikumar Malu Rafi Lekha M Nair Farida Nazeer Shaji Thomas Preethi Sara George Cessal Thommachan Kainickal Source Type: research