Systolic blood pressure lower than the heart rate indicates a poor outcome in patients with severe isolated traumatic brain injury: A Cross-Sectional Study
A systolic blood pressure (SBP) lower than the heart rate (HR) could indicate a poor condition in trauma patients. In such scenarios, the reversed shock index (RSI) is (Source: International Journal of Surgery)
Source: International Journal of Surgery - December 10, 2018 Category: Surgery Authors: Jin-Fu Huang, Yu-Chin Tsai, Cheng-Shyuan Rau, Shiun-Yuan Hsu, Peng-Chen Chien, Hsiao-Yun Hsieh, Ching-Hua Hsieh Tags: Original Research Source Type: research

Surgical outcomes of renal transplant recipients after abdominal surgery not connected with transplantation A retrospective case-control study
Due to the increasing number of patients after kidney transplantation, elective and emergency surgery of transplanted patients is becoming a relevant challenge in clinical routine. The current data on complication rate of patients after kidney transplantation, which must undergo another elective or emergency abdominal surgery, is inhomogeneous. Therefore, the aim of our study was to evaluate the outcome of renal transplant patients undergoing abdominal and abdominal wall surgery. (Source: International Journal of Surgery)
Source: International Journal of Surgery - December 9, 2018 Category: Surgery Authors: Ann-Kathrin Lederer, Dominic Haffa, Verena Martini, Roman Huber, Frank Makowiec, Stefan Fichtner-Feigl, Lampros Kousoulas Tags: Original Research Source Type: research

Additional Effect of Perioperative, Compared with Preoperative, Immunonutrition After Pancreaticoduodenectomy: A Randomized, Controlled Trial
We have reported that perioperative and preoperative immunonutrition reduced infectious complications in patients undergoing pancreaticoduodenectomy; however, it is unclear whether perioperative immunonutrition has additional effects compared with preoperative immunonutrition. The present study evaluated whether perioperative, compared with preoperative, immunonutrition has additional effects on cell-mediated immunity and the infection rate after pancreaticoduodenectomy. (Source: International Journal of Surgery)
Source: International Journal of Surgery - December 9, 2018 Category: Surgery Authors: Youhei Miyauchi, Katsunori Furukawa, Daisuke Suzuki, Hideyuki Yoshitomi, Tsukasa Takayashiki, Satoshi Kuboki, Masaru Miyazaki, Masayuki Ohtsuka Tags: Original Research Source Type: research

Portal vein embolization DOES not AFFECT the long-term survival and risk of cancer recurrence among colorectal liver metastases patients: A prospective cohort study
Previous studies comparing the survival outcomes of liver resections with and without preoperative portal vein embolization (PVE) for colorectal liver metastases (CLM) have linked PVE to higher rate of tumor progression, lower overall survival (OS) and lower disease-free survival (DFS). The lack of adjusted models to compare these outcomes is a limitation of these studies since patients requiring PVE may differ significantly from the ones receiving upfront surgery. (Source: International Journal of Surgery)
Source: International Journal of Surgery - December 8, 2018 Category: Surgery Authors: Yves Collin, Alex Par é, Assia Belblidia, Richard Létourneau, Marylène Plasse, Michel Dagenais, Simon Turcotte, Guillaume Martel, André Roy, Real Lapointe, Frank Vandenbroucke-Menu Tags: Original Research Source Type: research

Virtual reality simulator versus box-trainer to teach minimally invasive procedures: a meta-analysis
To evaluate the effectiveness of virtual reality simulator (VRS) training compared to box-trainer training (BT) for learning outcomes in minimally invasive surgery (MIS) techniques. Materials and Methods: A systematic review of the literature was performed using CENTRAL, MEDLINE, EMBASE, Scopus, CINAHL, LILACS. The primary outcomes were time to perform MIS and performance score in MIS. After being selected, the articles were evaluated for methodological quality and risk of bias. The results were evaluated for quality of evidence and meta-analysis was performed. (Source: International Journal of Surgery)
Source: International Journal of Surgery - December 7, 2018 Category: Surgery Authors: Hugo Gon çalo Guedes, Zêmia Maria Câmara Costa Ferreira, Layra Ribeiro de Sousa Leão, Edna Frasson Souza Montero, José Pinhata Otoch, Everson Luiz de Almeida Artifon Tags: Review Source Type: research

Serum amyloid a as an indicator of impending xenograft failure: Experimental studies
There is well-documented systemic inflammatory response in xenograft recipients to the presence of a pig graft. Serum amyloid A (SAA) is an inflammatory marker that is elevated in various pathological states. The assay used to measure it is (i) simple, (ii) relatively inexpensive, and (iii) provides an answer within minutes. (Source: International Journal of Surgery)
Source: International Journal of Surgery - December 3, 2018 Category: Surgery Authors: Guoqiang Zhang, Hidetaka Hara, Takayuki Yamamoto, Qi Li, Abhijit Jagdale, Yong Li, David K.C. Cooper, Hayato Iwase Tags: Original Research Source Type: research

Comparison of transperitoneal laparoscopic versus open adrenalectomy for large pheochromocytoma: a retrospective propensity score-matched cohort study
Surgical resection is the main treatment strategy for pheochromocytoma. Whether laparoscopic techniques are feasible for large pheochromocytoma treatments is controversial. The aim of this study was to evaluate the feasibility and safety of transperitoneal laparoscopic adrenalectomy (LA) compared with open adrenalectomy (OA). (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 29, 2018 Category: Surgery Authors: Song Bai, Zichuan Yao, Xianqing Zhu, Zidong Li, Yunzhong Jiang, Rongzhi Wang, Bin Wu Tags: Original Research Source Type: research

“Let the patient decide” – person-centered postoperative follow-up contacts, initiated via a phone app after day surgery: secondary analysis of a randomized controlled trial
Patients undergoing day surgery are expected to manage their recovery on their own. Follow-up routines differ, but many patients have expressed a need for more professional support during recovery. The aim of this study was to describe how many follow-up contacts were initiated, and when and why, via a digital solution. Also, we wanted to compare postoperative recovery and characteristics between patients requesting, and patients not requesting, contact. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 29, 2018 Category: Surgery Authors: Karuna Dahlberg, Maria Jaensson, Ulrica Nilsson Tags: Original Research Source Type: research

A novel hybrid fixation (percutaneous anterior pelvic bridge with K-wire) for the treatment of traumatic pelvic ring injury: A prospective study
The aim of the study was to introduce a novel percutaneous technique for the treatment of pelvic ring injuries using a percutaneous anterior pelvic bridge (PAPB) with K-wire. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 27, 2018 Category: Surgery Authors: Guangping Huang, Leyi Cai, Xufeng Jia, Yong Ji, Yu Zhou, Xiaping Mou, Qingmao Zhu, Fayou He, Zhaoyao Zhang Tags: Original Research Source Type: research

Bifidobacterium may benefit the prevention of necrotizing enterocolitis in preterm infants: A systematic review and meta-analysis
A systematic review and meta-analysis was designed to evaluate the efficacy and safety of Bifidobacterium for preventing necrotizing enterocolitis (NEC) in preterm infants. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 27, 2018 Category: Surgery Authors: Xiu-Li Zhu, Xiao-Gang Tang, Fan Qu, Yu Zheng, Wen-Hao Zhang, Yu-Qiao Diao Tags: Review Source Type: research

Laparoscopic vs. open left lateral sectionectomy: An update meta-analysis of randomized and non-randomized controlled trials
Left lateral sectionectomy (LLS) is thought to be the anatomical liver resection most suitable for the laparoscopic approach. Despite increasing popularity, comparative analysis of laparoscopic and open LLS are mostly limited to retrospective, underpowered studies with small sample size. Recent population-based studies and prospective trials have generated new data; however, this new body of knowledge has not been submitted systematic reviews or meta-analyses and high quality evidence regarding the actual benefits of minimally invasive LLS is lacking. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 26, 2018 Category: Surgery Authors: Rodrigo Luiz Macacari, Fabricio Ferreira Coelho, Wanderley Marques Bernardo, Jaime Arthur Pirola Kruger, Vagner Birk Jeismann, Gilton Marques Fonseca, Danielle Menezes Cesconetto, Ivan Cecconello, Paulo Herman Tags: Review Source Type: research

Development and validation of a nomogram predicting the probability of type a aortic dissection at a diameter below 55  mm: A retrospective cohort study
The study aims to build and validate a nomogram for estimating the probability of patients developing type A aortic dissection at a diameter less than 55  mm. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 26, 2018 Category: Surgery Authors: Jinlin Wu, Juntao Qiu, Wenxiang Jiang, Jiawei Qiu, Liang Zhang, Rui Zhao, Cuntao Yu Tags: Original Research Source Type: research

Critical steps for initiating an animal uterine transplantation model in sheep: experience from a case serie
In this study we describe through our experience the critical initial steps toward building a learning curve toward an optimal ovine uterine transplantation model. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 24, 2018 Category: Surgery Authors: Angeline FAVRE-INHOFER, Marie CARBONNEL, Aur élie REVAUX, Olivier SANDRA, Valérie MOUGENOT, Romain BOSC, Valérie GELIN, Arash RAFII, Barbara HERSANT, François VIALARD, Pascale CHAVATTE-PALMER, Christophe RICHARD, Jean-Marc AYOUBI Tags: Original Research Source Type: research

A practical risk scale for predicting morbidity and mortality in the emergency general surgical setting: A prospective multicenter study
Low albumin is a poor prognostic factor for surgical outcomes. We aimed to examine the predicative ability of easily obtainable point of care variables in combination to low albumin level to derive a practical risk scale for predicting older adults at risk of poor outcomes on admission to the emergency general surgical setting. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 24, 2018 Category: Surgery Authors: A.D. Ablett, K. McCarthy, B. Carter, L. Pearce, M. Stechman, S. Moug, W. Ceelen, J. Hewitt, P.K. Myint, Older Persons Surgical Outcomes Collaboration Tags: Original Research Source Type: research

The Mini-Gastric Bypass Original Technique
Mini-Gastric Bypass (MGB) is becoming more and more popular as shown by the numerous articles published over the past 15 years, supporting the operation as a short and simple procedure with excellent outcomes and low complication rates. There is still confusion amongst surgeons on the technique of the operation. The purpose of this paper is to review and describe the technique of MGB by its originators. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 23, 2018 Category: Surgery Authors: Robert Rutledge, Kuldeepak Kular, Naveen Manchanda Tags: Original Research Source Type: research

Intraoperative carbon nanoparticles mapping in secondary total thyroidectomy for recurrent thyroid nodules: Results of a 8-criterion case-match study (case control study)
In this study, we aimed to evaluate the efficacy and safety of intraoperative carbon nanoparticle (CN) mapping in patients undergoing secondary total thyroidectomy. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 22, 2018 Category: Surgery Authors: Xi Cheng, Haoran Feng, Lingxie Chen, Zhijian Jin, Tanglei Shao, Yue Wang, Juyong Liang, Hanxin Sun, Weiping Yang, Ren Zhao, Baiyong Shen, Jie Kuang, Jiqi Yan, Weihua Qiu Tags: Original Research Source Type: research

Effects of three common lumbar interbody fusion procedures for degenerative disc disease: A network meta-analysis of prospective studies
This study evaluated the pain and function caused by the LIF procedures for the treatment of patients with DDD. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 21, 2018 Category: Surgery Authors: En-Yuan Lin, Yu-Kai Kuo, Yi-No Kang Tags: Review Source Type: research

Man against the Machine - Differences in Surgical Risk Evaluation. A Cohort Prospective Study
The aim of this study was to compare the assessment provided by the ACS Surgical Risk Calculator with the assessments provided by senior and resident anesthesiologists. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 21, 2018 Category: Surgery Authors: Amir Hacohen Solovitz, Shimon Ivry, Ohad Ronen Tags: Original Research Source Type: research

Efficacy and safety of limb position on blood loss and range of motion after total knee arthroplasty without tourniquet: A randomized clinical trial
The purpose of this study was to investigate the effect of postoperative limb position on blood loss and knee function after primary total knee arthroplasty without tourniquet. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 20, 2018 Category: Surgery Authors: Yuangang Wu, Xiaoxi Lu, Yimei Ma, Yi Zeng, Huazhang Xiong, Xianchao Bao, Bin Shen Tags: Original Research Source Type: research

A propensity score-matched comparison of laparoscopic distal versus total gastrectomy for middle-third advanced gastric cancer
This study aimed to assess the long-term oncologic outcomes of laparoscopy-assisted distal gastrectomy (LADG) versus laparoscopy-assisted total gastrectomy (LATG) for middle-third AGC. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 20, 2018 Category: Surgery Authors: Wen-Jie Wang, Hong-Tao Li, Peng Chen, Jian-Ping Yu, Zuo-Yi Jiao, Xiao-Peng Han, Lin Su, Rui-Yu Tao, Lin Xu, Yan-Long Kong, Yu-Min Li, Hong-Bin Liu Tags: Original Research Source Type: research

Postoperative complications in elderly patients following pancreaticoduodenectomy lead to increased postoperative mortality and costs. A retrospective cohort study
Complications frequently occur after pancreaticoduodenectomy. Patients undergoing pancreaticoduodenectomy tend to be older; age and postoperative complication may be associated. To clarify this association, we compared postoperative outcomes in patients undergoing pancreaticoduodenectomy based on age group. We aimed to determine whether we could identify an age cutoff where the incidence and cost of postoperative complications starts increasing and potentially outweigh the potential benefits of pancreaticoduodenectomy. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 20, 2018 Category: Surgery Authors: Fang Yuan, Yasmin Essaji, Emilie P. Belley-Cote, Amiram Gafni, Lekhini Latchupatula, Leyo Ruo, Pablo E. Serrano Tags: Original Research Source Type: research

Risk factors for postoperative severe morbidity after pheochromocytoma surgery: a single center retrospective analysis of 262 patients
Surgical resection is the primary treatment strategy for pheochromocytoma; however, it carries a high risk of morbidity and mortality. The risk factors for severe morbidity remain unclear and require further exploration. We aimed to identify the risk factors for severe morbidity after pheochromocytoma surgery in Chinese patients. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 20, 2018 Category: Surgery Authors: Song Bai, Zichuan Yao, Xianqing Zhu, Zidong Li, Yunzhong Jiang, Rongzhi Wang, Bin Wu Tags: Original Research Source Type: research

Prognostic role of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in prostate cancer: a meta-analysis of results from multivariate analysis
The prognostic role of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with prostate cancer (PCa) remains inconsistent. Here we quantify the prognostic impact of these biomarkers and assess their consistency in PCa. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 20, 2018 Category: Surgery Authors: Jinan Guo, Jiequn Fang, Xiangjiang Huang, Yanfeng Liu, Yeqing Yuan, Xueqi Zhang, Chang Zou, Kefeng Xiao, Jianhong Wang Tags: Review Source Type: research

Factors predictive of the development of surgical site infection in thyroidectomy – An analysis of NSQIP database
Surgical Site Infection (SSI) is an uncommon but serious complication of thyroidectomy when encountered. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 16, 2018 Category: Surgery Authors: David Myssiorek, Yasmina Ahmed, Afshin Parsikia, Maria Castaldi, John McNelis Tags: Review Source Type: research

Analysis of the first 2645 registrations at the Research Registry ®: a global repository for all study types involving human participants
The Declaration of Helsinki has called for the registration of all research studies involving human participants. Despite this, prior registries did not allow registration certain study types, or retrospective registration. The Research Registry ® (www.researchregistry.com) was established in 2015 to provide a venue of registration for any study involving human participants. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 15, 2018 Category: Surgery Authors: Alexander J. Fowler, Naeem Dowlut, Richard Limb, Martinique Vella Baldacchino, Vinay Sonagara, Natalie George, Rachel Thavayogan, Buket Gundogan, Christopher Limb, Daniyal J. Jafree, Riaz A. Agha Tags: Original Research Source Type: research

Is opening-wedge high tibial osteotomy superior to closing-wedge high tibial osteotomy in treatment of unicompartmental osteoarthritis? A meta-analysis of randomized controlled trials
High tibial osteotomy (HTO) is an effective surgical technique that can stop or inhibit progression of knee osteoarthritis (OA) and avoid or postpone the need for knee arthroplasty. This meta-analysis determined whether opening-wedge high tibial osteotomy (OWHTO) was superior to closing-wedge high tibial osteotomy (CWHTO) in treatment of unicompartmental OA. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 13, 2018 Category: Surgery Authors: Zhan Wang, Yihua Zeng, Wei She, Xiangli Luo, Liyang Cai Tags: Review Source Type: research

Title: Comparison of effects of four treatment methods for unstable intertrochanteric fractures:a network meta-analysis
The optimal internal fixation device for unstable intertrochanteric fracture remains a matter of controversy. By performing network meta-analysis, we developed a ranking of the following four surgical methods: proximal femoral nail antirotation, InterTan nail, gamma nail (GN) and sliding hip screws. We compare the complication rates in patients with unstable intertrochanteric fractures. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 13, 2018 Category: Surgery Authors: Wu-Bin Shu, Xiao-bo Zhang, Hua-ya Lu, He-Hui Wang, Guan-Hua Lan Tags: Review Source Type: research

Clinical utility of radioactive seed localization in nonpalpable breast cancer: A Retrospective single institutional cohort study
In this study, we compared WL and RSL, focusing on the relationship between the techniques and in-breast recurrence or margin positivity. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 12, 2018 Category: Surgery Authors: Badria Aljohani, Klaudia Jumaa, Anat Kornecki, Muriel Brackstone Tags: Original Research Source Type: research

Safe Laparoscopic Cholecystectomy: A Systematic Review of Bile Duct Injury Prevention
Since the introduction of laparoscopic cholecystectomy (LC), a substantial increase in bile duct injury (BDI) incidence was noted. Multiple methods to prevent this complication have been developed and investigated. The most suitable method however is subject to debate. In this systematic review, the different modalities to aid in the safe performance of LC and prevent BDI are delineated. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 12, 2018 Category: Surgery Authors: Floyd W. van de Graaf, Ina Za ïmi, Laurents P.S. Stassen, Johan F. Lange Tags: Review Source Type: research

Comparison of suture button fixation and syndesmotic screw fixation in the treatment of distal tibiofibular syndesmosis injury: a systematic review and meta-analysis
This systematic review and meta-analysis was performed to investigate the outcomes of syndesmotic screw fixation versus suture button fixation in the treatment of distal tibiofibular syndesmosis injury from the current literatures. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 12, 2018 Category: Surgery Authors: Linzhen Xie, Huanguang Xie, Jinwu Wang, Chunhui Chen, Chuanxu Zhang, Hua Chen, Wenhao Zheng Tags: Review Source Type: research

Comparison of OnabotulinumtoxinA versus Sacral neuromodulation for refractory urinary urge incontinence: a systematic review and meta-analysis of randomized controlled trials
Both intradetrusor OnabotulinumtoxinA (BTX) and Sacral neuromodulation (SNM) as third-line therapies for urgency urinary incontinence (UUI) are increasingly being utilized. However, there are differences in preference between patients and medical personnel in clinical practice. This meta-analysis was designed to compare BTX versus SNM in treatment of UUI. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 8, 2018 Category: Surgery Authors: Heng-Li Niu, Yun-Hai Ma, Cheng-Jun Zhang Tags: Review Source Type: research

Trans-anal or Trans-abdominal total mesorectal excision? A systematic review and meta-analysis of recent comparative studies on perioperative outcomes and pathological result
Trans-anal total mesorectal resection (TaTME) is a novel approach for rectal cancer. However, the perioperative and pathological outcomes of this procedure remain controversial. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 8, 2018 Category: Surgery Authors: PuRun Lei, Ying Ruan, Xiaofeng Yang, Jiafeng Fang, Tufeng Chen Tags: Review Source Type: research

Management of distal radius fracture: a comparison of actual and theoretical treatments
The objective of this study was to explore whether there were any differences between the theoretical operative treatment of distal radius fractures according to AAOS guideline on basis of measurement of radiographs and the treatment they actually received in our institution. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 8, 2018 Category: Surgery Authors: Linzhen Xie, Chunhui Chen, Xianbin Yu, Wei Hu, Hua Chen, Liaojun Sun Tags: Original Research Source Type: research

Increasing the participation of medical students in surgical research: The Italian case and the role of research collaboratives
Research collaboratives represent an innovative and effective platform to deliver multicentric prospective studies that impact clinical practice. Over the past 10 years, student- and trainee-led surgical research collaboratives have flourished in the UK and allowed the completion of high-quality multicentre studies, with rapid recruitment of large numbers of patients [1]. Following this model, the first pan-European student- and trainee-led surgical research collaborative (EuroSurg) was established in 2015. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 7, 2018 Category: Surgery Authors: A. Sgr ò, A. Simioni, V. Farina, S. Pasquali, G. Pellino, F. Pata Tags: Letter to the Editor Source Type: research

Evaluation of Fowler –Stephens orchiopexy for high-level intra-abdominal cryptorchidism: A systematic review and meta-analysis
What Is Already Known On This Topic: Laparoscopy is the gold standard for accurate diagnosis of undescended intra-abdominal testes (IATs). Laparoscopy or primary orchiopexy, performed in a single stage, are both acceptable for low-level IATs. However, the surgical strategy for high-level IATs remains controversial. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 5, 2018 Category: Surgery Authors: Chengjun Yu, Chunlan Long, Yi Wei, Xiangliang Tang, Bin Liu, Lianju Shen, Xueyi Dong, Tao Lin, Dawei He, Shengde Wu, Guanghui Wei Tags: Review Source Type: research

Relationship between Clavien –Dindo classification and long-term survival outcomes after curative resection for gastric cancer: a propensity score-matched analysis
The impact of postoperative complications (POCs) on the long-term survival outcomes after curative resection for gastric cancer has seldom been reported. The purpose of this study was to evaluate the relationship between the severity of POCs and long-term survival outcomes after curative resection for gastric cancer. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 3, 2018 Category: Surgery Authors: Zhengyan Li, Bin Bai, Gang Ji, Jipeng Li, Qingchuan Zhao Tags: Original Research Source Type: research

Development of a Malawi Intensive care Mortality risk Evaluation (MIME) Model, a Prospective Cohort Study
Intensive care medicine can contribute to population health in low-income countries by reducing premature mortality related to surgery, trauma, obstetrical and other medical emergencies. Quality improvement is guided by risk stratification models, which are developed primarily within high-income settings. Models validated for use in low-income countries are needed. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 2, 2018 Category: Surgery Authors: Meghan Prin, Stephanie Pan, Clement Kadyaudzu, Guohua Li, Anthony Charles Tags: Original Research Source Type: research

#1 Reinforcement of Closure of Stoma Site (ROCSS) randomized controlled trial: A multicentre, international evaluation of biological mesh reinforcement of stoma (oral presentation)
Background: Closure of complex and contaminated abdominal wounds is challenging, with high complication rates, including wound dehiscence and incisional hernias. Stoma closure is a controlled example of such a wound. The Reinforcement of Closure of Stoma Site (ROCSS) trial aimed to assess whether a biologic mesh (collagen tissue matrix) safely reduces the incidence of stoma closure incisional hernias. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: J. Glasbey, the Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and the West Midlands Research Collaborative Source Type: research

#2 Let ’s not talk about it: a conceptual study of surgical innovation (oral presentation)
Background: Effective evaluation and governance of surgical innovation is impeded by difficulties in defining surgical innovation. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: G. Birchley, R. Huxtable, J. Ives, J.M. Blazeby Source Type: research

#3 PIRRIST: A patient and public involvement (PPI) intervention to enhance recruitment and retention in surgical trials (oral presentation)
Background: Poor recruitment and retention are common challenges to the successful delivery of surgical trials. Patient and public involvement (PPI) has the potential to improve recruitment and retention in surgical trials but there have been few attempts to investigate this. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: J. Crocker, S. Rees, L. Locock, S. Petit-Zeman, A. Chant, S. Treweek, J. Cook, N. Farrar, K. Woolfall, J. Bostock, R. Harmston, A. Ferrey, R. Bulbulia Source Type: research

#4 Development and delivery of a standardised investigator training package for an IDEAL phase 3 multicentre interventional trial across low and middle income settings (oral presentation)
This study describes the development and delivery of a standardised investigator training package for an IDEAL phase 3 interventional surgical randomised trial across low and middle income countries (LMICs). (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: J. Glasbey Source Type: research

#5 Scottish Health Technologies Group Experience of Using IDEAL (oral presentation)
Background: The Scottish Health Technologies Group (SHTG) provides evidence-based advice to the Scottish NHS on the clinical and cost-effectiveness of health technologies, which are defined to include devices, diagnostics, medical and surgical procedures and organizational systems used in health and social care. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: J. Hislop, L. Gaianu, J. Harbour, J. Kelly, K. MacPherson, L. Thompson, E. Clifton Source Type: research

#6 Learning curve bias can significantly influence results of high quality surgical RCTs: the case of the Dutch D1-D2 trial (oral presentation)
Background: Learning curves are often observed after introduction of innovative surgical techniques, but it is currently unknown whether learning curves can influence the outcome of high quality surgical randomised controlled trials (RCTs). (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: F. Van Workum, G. Hannink, J.J. Bonenkamp, C. Van de Velde, I. Nagtegaal, M. Rovers, C. Rosman Source Type: research

#7 A systematic review of the ethical, legal and regulatory issues pertaining to surgical innovation (oral presentation)
Background: There are a number of ethical concerns when discussing surgical innovation including accountability, harms to patients and conflicts of interest. Whilst some preliminary research has been undertaken to conceptualise surgical innovation, and its identifiable ethical issues, and some discussion has arisen as a result of new surgical procedures going wrong, it is unclear if innovation has been discussed in sufficient detail. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: A. Toms Source Type: research

#8 Introducing innovative invasive procedures and devices into clinical practice: an in-depth analysis of NHS Trusts ’ New Invasive Procedure governance (oral presentation)
Background: The introduction of pharmaceutical products into clinical practice is strictly governed, however regulation surrounding new invasive procedures and devices is less clear. Invasive procedures and devices may be introduced with research approvals, and NHS Trusts may also allow introduction using local Trust policies. The latter have not been previously studied. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: S. Cousins, H. Richards, J. Zahra, D. Elliott, K. Avery, H. Robertson, S. Paramasivan, N. Wilson, J. Mathews, Z. Tolkein, B. Main, N.S. Blencowe, R. Hinchliffe, J.M. Blazeby Source Type: research

#9 An in-depth analysis and cohort study of the techniques used to repair complex incisional hernias after abdominal surgery (oral presentation)
Rationale: Incisional hernias develop in approximately 15% of patients following midline incisions for abdominal surgery. Midline fascial reconstruction with mesh reinforcement is the recommended technique, but often requires separation of the abdominal wall layers (component separation). Anterior component separation has been used, but recently posterior component separation (PCS) has been introduced to improve outcomes. However, the PCS technique is still developing and has not been widely implemented. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: S. Pathak, N. Smart, J. Rees, J.M. Blazeby, D. Messenger Source Type: research

#10 Portuguese Inguinal Hernia Cohort Study (oral presentation)
Rationale: Inguinal hernia repair with mesh has been documented to be associated with chronic pain in a minority of patients. However, the individual prediction of the development of chronic pain is still not possible and different countries expressed differences in the incidence of this complication. The factors leading to these differences have still not been identified. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: Portuguese Surgical Research Collaborative:, A.S. Soares, A.A. Jo ão, J. Simões, M. Peyroteo, J.M. Azevedo Source Type: research

#11 The Pre-Bra Study (oral presentation)
Rationale: Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive technique worldwide. Pre-pectoral reconstruction in which the implant, wrapped in mesh, is placed on top of the muscle is the latest innovation but subcutaneous IBBR was previously abandoned due to high complication rates. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: K. Harvey, S. Potter, N. Mills, C. Holcombe Source Type: research

#12 Proposed randomised controlled feasibility trial of a novel polyvinylideneflouride (PVDF) mesh (Dynamesh ®-HIATUS) cruroplasty versus suture-only repair of large hiatus hernia: the DYNAMIC Study (oral presentation)
Background: Gastro-oesophageal reflux disease (GORD) is a significant health problem affecting up to 25% of adults. Keyhole surgical treatment of chronic GORD has become an alternative to medical treatment over the past 20 years. However, patients with large hiatus hernias more than 5cm in size appear to have poorer results with recurrence in up to half of the patients. The use of mesh reinforcement has been considered to improve this, as this has been efficacious in other hernia repairs. However, with hiatal hernia repair there have been concerns about risks of mesh erosion and infection, and results to date have been equ...
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: S. Toh, B. Knight, C. Fogg, E. Baddesley, A. Higginson, R. Beable, S. Babu, E. Hawes, M. Moon, J. Shoebridge, P. Meredith, M. Amos-Lyons, P. May-Miller Source Type: research

#13 A systematic review to assess the reporting of surgical innovation: a case study of the Subdural Evacuating Port System (SEPS) (poster presentation)
Background: The evaluation and reporting of innovations in surgery are often to a poor standard. In response to this, the IDEAL framework (Idea, Development, Exploration, Assessment, Long-term follow-up) was developed, aiming to improve the developmental process and outcome reporting of surgical innovations. The Subdural Evacuating Port System (SEPS) is a new approach for the evacuation of chronic and subacute haematomas. A novel variant of the twist-drill craniotomy, the SEPS poses several advantages to current management options, including a reduced pneumocephalus risk and the need for only local anaesthesia. (Source: In...
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: A.T. Storrar, B.G. Main, J.M. Blazeby, A. Kolias, N.S. Blencowe Source Type: research