Determination of optimum levels of binding antibody units (BAU) of new quantitative chemiluminescent immuno-assay (CLIA) in COVID-19 vaccinated volunteer blood donors
This study was undertaken to determine optimum levels of binding antibody units (BAU/ml) in new quantitative chemiluminescent assay (CLIA) that corresponded to neutralizing potential (30% inhibition) of sVNT assay. Methods: Ninety-one blood samples were analyzed by CLIA and sVNT assays. Test samples (n=75) were collected from blood donors post-2nd vaccination dose, while control samples (n=16) were archived pre-COVID donor samples. (Source: Transfusion and Apheresis Science)
Source: Transfusion and Apheresis Science - April 24, 2024 Category: Hematology Authors: Aseem Kumar Tiwari, Geet Aggarwal, Pratibha Kale, Neeti Yadav, Virendra Kumar, Gargi Singh, K. Cheirmaraj, K. Krishnan Source Type: research
Creating a Palliative Care Clinic for Patients with Cancer Pain and Substance Use Disorder
Opioids are a first-line treatment for severe cancer pain. However, clinicians may be reluctant to prescribe opioids for patients with concurrent substance use disorders (SUD) or clinical concerns about non-prescribed substance use. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 24, 2024 Category: Palliative Care Authors: Sachin S. Kale, Gennaro Di Tosto, Laura J. Rush, Justin Kullgren, Deborah Russell, Martin Fried, Blessing Igboeli, Julie Teater, Katie Fitzgerald Jones, Devon K. Check, Jessica Merlin, Ann Scheck McAlearney Tags: Brief Quality Improvement Report Source Type: research
Evidence on the inhibitory effect of Brassica plants against Acinetobacter baumannii lipases: phytochemical analysis, in vitro, and molecular docking studies
CONCLUSION: This study emphasizes the significance of Brassica vegetables as a novel natural source of potential inhibitors of lipase from A. baumannii.PMID:38641582 | PMC:PMC11027383 | DOI:10.1186/s12906-024-04460-y (Source: Molecular Medicine)
Source: Molecular Medicine - April 19, 2024 Category: Molecular Biology Authors: Manal M Sabry Ali M El-Halawany Walaa G Fahmy Basma M Eltanany Laura Pont Fernando Benavente Ahmed S Attia Farag F Sherbiny Rana M Ibrahim Source Type: research
Care for Patients with Substance Use: A Qualitative Study of Oncology Team Experiences and the Role of Palliative Care (RP106)
1. Illustrate challenges oncology teams may face when providing care for patients with concurrent substance use disorder and cancer2. Improve understanding of gaps in cancer care that may be addressed with collaboration between palliative care and oncology care teams to treat patients with substan ce use disorders to improve comprehensive cancer treatment for this patient population. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Sachin Kale, Jennifer Eramo, Laura Rush, Sadie Chen, Mireille Bitangacha, Elizabeth Mayers, AnnScheck McAlearney, Amanda V. Gusovsky Source Type: research
The Oral-Lung Microbiome Axis in Connective Tissue Disease-Related Interstitial Lung Disease
Semin Respir Crit Care Med. 2024 Apr 16. doi: 10.1055/s-0044-1785673. Online ahead of print.ABSTRACTConnective tissue disease-related interstitial lung disease (CTD-ILD) is a frequent and serious complication of CTD, leading to high morbidity and mortality. Unfortunately, its pathogenesis remains poorly understood; however, one intriguing contributing factor may be the microbiome of the mouth and lungs. The oral microbiome, which is a major source of the lung microbiome through recurrent microaspiration, is altered in ILD patients. Moreover, in recent years, several lines of evidence suggest that changes in the oral and lu...
Source: Respiratory Care - April 16, 2024 Category: Respiratory Medicine Authors: Kale S Bongers Angeline Massett David N O'Dwyer Source Type: research
Preparation of pH-sensitive porous polylactic acid-based medical dressing with self-pumping function
In this study, we fabricated a pH-sensitive colorimetric chronic wound dressing with self-pumping function using electrostatic spinning technology. It consisted of three layers: a polylactic acid-curcumin (PCPLLA) hydrophobic layer, a hydrolyzed polyacrylonitrile (HPAN) transfer layer, and a polyacrylonitrile-purple kale anthocyanin (PAN-PCA) hydrophilic layer. The results showed that the preparation of porous PLLA fiber membrane loaded with 0.2 % Cur was achieved by adjusting the spinning-related parameters, which could ensure that the composite dressing had sufficient anti-inflammatory, antibacterial and antioxidant prop...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Zijian Zhang Jianyong Li Yi Wang Xiaojie Wang Liming Wang Yinghua Qiu Fangyi Li Jianfeng Li Maocheng Ji Jia Man Source Type: research
The Oral-Lung Microbiome Axis in Connective Tissue Disease-Related Interstitial Lung Disease
Semin Respir Crit Care Med. 2024 Apr 16. doi: 10.1055/s-0044-1785673. Online ahead of print.ABSTRACTConnective tissue disease-related interstitial lung disease (CTD-ILD) is a frequent and serious complication of CTD, leading to high morbidity and mortality. Unfortunately, its pathogenesis remains poorly understood; however, one intriguing contributing factor may be the microbiome of the mouth and lungs. The oral microbiome, which is a major source of the lung microbiome through recurrent microaspiration, is altered in ILD patients. Moreover, in recent years, several lines of evidence suggest that changes in the oral and lu...
Source: Respiratory Care - April 16, 2024 Category: Respiratory Medicine Authors: Kale S Bongers Angeline Massett David N O'Dwyer Source Type: research
Preparation of pH-sensitive porous polylactic acid-based medical dressing with self-pumping function
In this study, we fabricated a pH-sensitive colorimetric chronic wound dressing with self-pumping function using electrostatic spinning technology. It consisted of three layers: a polylactic acid-curcumin (PCPLLA) hydrophobic layer, a hydrolyzed polyacrylonitrile (HPAN) transfer layer, and a polyacrylonitrile-purple kale anthocyanin (PAN-PCA) hydrophilic layer. The results showed that the preparation of porous PLLA fiber membrane loaded with 0.2 % Cur was achieved by adjusting the spinning-related parameters, which could ensure that the composite dressing had sufficient anti-inflammatory, antibacterial and antioxidant prop...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Zijian Zhang Jianyong Li Yi Wang Xiaojie Wang Liming Wang Yinghua Qiu Fangyi Li Jianfeng Li Maocheng Ji Jia Man Source Type: research
The Oral –Lung Microbiome Axis in Connective Tissue Disease-Related Interstitial Lung Disease
Semin Respir Crit Care Med DOI: 10.1055/s-0044-1785673Connective tissue disease-related interstitial lung disease (CTD-ILD) is a frequent and serious complication of CTD, leading to high morbidity and mortality. Unfortunately, its pathogenesis remains poorly understood; however, one intriguing contributing factor may be the microbiome of the mouth and lungs. The oral microbiome, which is a major source of the lung microbiome through recurrent microaspiration, is altered in ILD patients. Moreover, in recent years, several lines of evidence suggest that changes in the oral and lung microbiota modulate the pulmonary immune re...
Source: Seminars in Respiratory and Critical Care Medicine - April 16, 2024 Category: Respiratory Medicine Authors: Bongers, Kale S. Massett, Angeline O'Dwyer, David N. Tags: Review Article Source Type: research
Rh(III)-catalysed C-H annulation of cis-stilbene acids with 2-diazo-1,3-diketones: A facile access to 6,7-dihydrobenzofuran-4(5H)-one and α-pyrone scaffolds
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00151F, PaperShankaraiah Nagula, Mary Sravani Galla, Nandini B. Kale, Akshay Kumawat, Darshana Bora An efficient Rh(III)-catalysed C-H functionalization, tandem annulation of cis-stilbene acids using 2-diazo-1,3-diketones was devised. The protocol has solely afforded 6,7-dihydrobenzofuran-4(5H)-ones using alicyclic diazocarbonyls via decarbonylation and α-pyrones with aliphatic diazo... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - April 15, 2024 Category: Molecular Biology Authors: Shankaraiah Nagula Source Type: research
Elemental composition and potential health risk of vegetable cultivated in residential area situated close to abandoned gold mine dump: Characteristics of soil quality on the vegetables
This study mainly aimed to investigate the elemental distribution of both toxic and essential elements in soils and leafy vegetables (Brassica oleracea) collected from eight different sites around the Davidsonville residential area, located closer to the abandoned Princess gold mine dump, Johannesburg, South Africa. The nutritional value of vegetables in the human diet was determined to assess their value to their health. The vegetables contained metals in the following descending order: Ca > Mg > Ca > Sb > Pb > Fe > Mo > Cr > Se > As > V > Ni > Co > Cd. The bioaccumulation factor (BA...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 15, 2024 Category: Environmental Health Authors: Sihle Mngadi Philiswa Nosizo Nomngongo Shadung Moja Source Type: research
Elemental composition and potential health risk of vegetable cultivated in residential area situated close to abandoned gold mine dump: Characteristics of soil quality on the vegetables
This study mainly aimed to investigate the elemental distribution of both toxic and essential elements in soils and leafy vegetables (Brassica oleracea) collected from eight different sites around the Davidsonville residential area, located closer to the abandoned Princess gold mine dump, Johannesburg, South Africa. The nutritional value of vegetables in the human diet was determined to assess their value to their health. The vegetables contained metals in the following descending order: Ca > Mg > Ca > Sb > Pb > Fe > Mo > Cr > Se > As > V > Ni > Co > Cd. The bioaccumulation factor (BA...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 15, 2024 Category: Environmental Health Authors: Sihle Mngadi Philiswa Nosizo Nomngongo Shadung Moja Source Type: research
Elemental composition and potential health risk of vegetable cultivated in residential area situated close to abandoned gold mine dump: Characteristics of soil quality on the vegetables
This study mainly aimed to investigate the elemental distribution of both toxic and essential elements in soils and leafy vegetables (Brassica oleracea) collected from eight different sites around the Davidsonville residential area, located closer to the abandoned Princess gold mine dump, Johannesburg, South Africa. The nutritional value of vegetables in the human diet was determined to assess their value to their health. The vegetables contained metals in the following descending order: Ca > Mg > Ca > Sb > Pb > Fe > Mo > Cr > Se > As > V > Ni > Co > Cd. The bioaccumulation factor (BA...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 15, 2024 Category: Environmental Health Authors: Sihle Mngadi Philiswa Nosizo Nomngongo Shadung Moja Source Type: research
A cubic Sm@CdS Q-Dot glass as a photocatalyst for solar H2 generation
New J. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4NJ00050A, PaperVijay Autade, Rajendra Popat Panmand, Sandeep Annasaheb Arote, Reshma Ballal, Sonali D Naik, Milind Kulkarni, Bharat B Kale The cubic Sm@CdS quantum dots (QDs) are grown in the glass matrix with good thermal stability for the first time. The band gap of CdS particles embedded in glass is... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - April 12, 2024 Category: Chemistry Authors: Vijay Autade Source Type: research
Molecules, Vol. 29, Pages 1727: Studies on the Effects of Fermentation on the Phenolic Profile and Biological Activity of Three Cultivars of Kale
This study aimed to investigate how different treatments (spontaneous fermentation or fermentation with the use of starter culture) affect phenolic content, antioxidant potential, and cholinesterase inhibitory activity in different kale cultivars: ‘Halbhoner Grüner Krauser’, ‘Scarlet’, and ‘Nero di Toscana’. Chosen samples were further tested for their protective potential against the Caco-2 cell line. HPLC-MS analysis revealed that the fermentation affected the composition of polyphenolic compounds, leading to an increase in t...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Magdalena Michalak-Tomczyk Anna Rymuszka Wirginia Kukula-Koch Dominik Szwajgier Ewa Baranowska-W ójcik Jacek Jachu ła Agnieszka Welman-Styk Kinga K ędzierska Tags: Article Source Type: research
