Monthly variation of fatty acids, lipid quality index and metal content of Pontastacus leptodactylus (Eschscholtz, 1823) in Atikhisar Dam Lake (Çanakkale, Türkiye)
This study aims to investigate the metal content, fatty acid composition, lipid quality, and potential health risks of Pontastacus leptodactylus crayfish inhabiting Atikhisar Dam Lake. The research covers a 12-month period and includes both male and female individuals. The study investigated the metal content of crayfish specimens. In female individuals, the metal concentrations were ranked as Fe > Zn > Al > Cu > Mn > Se > As > Hg > Cd > Pb, while in male individuals, the ranking was Fe > Al > Zn > Cu > Mn > Se > As > Hg > Pb > Cd. The results demonstrate that Atherogen...
Source: Environmental Science and Pollution Research International - March 19, 2024 Category: Environmental Health Authors: Sel çuk Berber Sefa Acarl ı Bar ış Bayraklı Semih Kale Bayram K ızılkaya Pervin Vural Deniz Acarl ı Source Type: research
Reducing Salivary Toxicity with Adaptive Radiotherapy (ReSTART): A Randomized Controlled Trial comparing conventional IMRT to adaptive IMRT in head and neck Squamous Cell Carcinomas
The utility of Adaptive Radiotherapy (ART) in Head and Neck Squamous Cell Carcinoma (HNSCC) remains to be ascertained. While multiple retrospective and single-arm prospective studies have demonstrated its efficacy in decreasing parotid doses and reducing xerostomia, there is a lack of adequate randomized evidence. (Source: Clinical Oncology)
Source: Clinical Oncology - March 18, 2024 Category: Radiology Authors: Sarbani Ghosh-Laskar, Shwetabh Sinha, Anuj Kumar, Asesh Samanta, Samarpita Mohanty, Srikant Kale, Faizalam Khan, Shirley Lewis Salins, Vedang Murthy Tags: Original Article Source Type: research
Sensors, Vol. 24, Pages 1916: Investigation of Using Hyperspectral Vegetation Indices to Assess Brassica Downy Mildew
This study aims to evaluate different vegetation indices to assess different downy mildew infection levels in the Brassica variety Mildis using hyperspectral data. Artificial inoculation using H. brassicae sporangia suspension was conducted to induce different levels of downy mildew disease. Spectral measurements, spanning 350 nm to 1050 nm, were conducted on the leaves using an environmentally controlled setup, and the reflectance data were acquired and processed. The Successive Projections Algorithm (SPA) and signal sensitivity calculation were used to extract the most informative wavelengths that could be used to develo...
Source: Sensors - March 16, 2024 Category: Biotechnology Authors: Bo Liu Marco Antonio Fernandez Taryn Michelle Liu Shunping Ding Tags: Article Source Type: research
Revisiting the Mitochondrial Function and Communication in Neurodegenerative Diseases
Curr Pharm Des. 2024 Mar 12. doi: 10.2174/0113816128286655240304070740. Online ahead of print.ABSTRACTNeurodegenerative disorders are distinguished by the progressive loss of anatomically or physiologically relevant neural systems. Atypical mitochondrial morphology and metabolic malfunction are found in many neurodegenerative disorders. Alteration in mitochondrial function can occur as a result of aberrant mitochondrial DNA, altered nuclear enzymes that interact with mitochondria actively or passively, or due to unexplained reasons. Mitochondria are intimately linked to the Endoplasmic reticulum (ER), and ER-mitochondrial ...
Source: Current Pharmaceutical Design - March 14, 2024 Category: Drugs & Pharmacology Authors: Nitu L Wankhede Mayur B Kale Mohit D Umare Sanket Lokhande Aman B Upaganlawar Pranay Wal Brijesh G Taksande Milind J Umekar Prasanna Shama Khandige Bhupendra Singh Vandana Sadananda Seema Ramniwas Tapan Behl Source Type: research
Revisiting the Mitochondrial Function and Communication in Neurodegenerative Diseases
Curr Pharm Des. 2024 Mar 12. doi: 10.2174/0113816128286655240304070740. Online ahead of print.ABSTRACTNeurodegenerative disorders are distinguished by the progressive loss of anatomically or physiologically relevant neural systems. Atypical mitochondrial morphology and metabolic malfunction are found in many neurodegenerative disorders. Alteration in mitochondrial function can occur as a result of aberrant mitochondrial DNA, altered nuclear enzymes that interact with mitochondria actively or passively, or due to unexplained reasons. Mitochondria are intimately linked to the Endoplasmic reticulum (ER), and ER-mitochondrial ...
Source: Current Pharmaceutical Design - March 14, 2024 Category: Drugs & Pharmacology Authors: Nitu L Wankhede Mayur B Kale Mohit D Umare Sanket Lokhande Aman B Upaganlawar Pranay Wal Brijesh G Taksande Milind J Umekar Prasanna Shama Khandige Bhupendra Singh Vandana Sadananda Seema Ramniwas Tapan Behl Source Type: research
Comparative study of the quality indices, antioxidant substances, and mineral elements in different forms of cabbage
In this study, f... (Source: BMC Plant Biology)
Source: BMC Plant Biology - March 14, 2024 Category: Biology Authors: Zhibin Yue, Guobin Zhang, Jie Wang, Jue Wang, Shilei Luo, Bo Zhang, Zhaozhuang Li and Zeci Liu Tags: Research Source Type: research
Agmatine as a Novel Intervention for Alzheimer's Disease: Pathological Insights and Cognitive Benefits
Ageing Res Rev. 2024 Mar 11:102269. doi: 10.1016/j.arr.2024.102269. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by progressive cognitive decline and a significant societal burden. Despite extensive research and efforts of the multidisciplinary scientific community, to date, there is no cure for this debilitating disease. Moreover, the existing pharmacotherapy for AD only provides symptomatic support and does not modify the course of the illness or halt the disease progression. This is a significant limitation as the underlying pathology of the disease con...
Source: Ageing Research Reviews - March 13, 2024 Category: Genetics & Stem Cells Authors: Raj A Katariya Shivkumar S Sammeta Mayur B Kale Nandkishor R Kotagale Milind J Umekar Brijesh G Taksande Source Type: research
Agmatine as a Novel Intervention for Alzheimer's Disease: Pathological Insights and Cognitive Benefits
Ageing Res Rev. 2024 Mar 11:102269. doi: 10.1016/j.arr.2024.102269. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by progressive cognitive decline and a significant societal burden. Despite extensive research and efforts of the multidisciplinary scientific community, to date, there is no cure for this debilitating disease. Moreover, the existing pharmacotherapy for AD only provides symptomatic support and does not modify the course of the illness or halt the disease progression. This is a significant limitation as the underlying pathology of the disease con...
Source: Ageing Research Reviews - March 13, 2024 Category: Genetics & Stem Cells Authors: Raj A Katariya Shivkumar S Sammeta Mayur B Kale Nandkishor R Kotagale Milind J Umekar Brijesh G Taksande Source Type: research
Comprehensive study on the differential extraction and comparison of bioactive health potential of the Broccoli ( < em > Brassica oleracea < /em > )
Conclusions: Acetonitrile and aqueous extraction of broccoli might be an ideal choice for extraction methods, which show increased extraction yield and antioxidant and anti-inflammatory potentials. Utilization of phytomolecules from natural sources is a promising alternative approach to synthetic drug development.PMID:38464834 | PMC:PMC10920836 | DOI:10.7150/ijms.92456 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - March 11, 2024 Category: Biomedical Science Authors: Durga Uvaraj Naiyf S Alharbi Shine Kadaikunnan Muthu Thiruvengadam Baskar Venkidasamy Source Type: research
