[18 F] -FAPI-42 PET/CT assessment of Progressive right ventricle fibrosis under pressure overload
Right heart failure (RHF) is a complication of pulmonary hypertension (PH) and increases the mortality independently of the underlying disease. However, the process of RHF development and progression is not fu... (Source: Respiratory Research)
Source: Respiratory Research - November 6, 2023 Category: Respiratory Medicine Authors: Xiaohui Zeng, Ruiyue Zhao, Zhixiong Wu, Zhuoji Ma, Chunxian Cen, Shanshan Gao, Wanxian Hong, Yanrong Yao, Kexin Wen, Shangwei Ding, Jian Wang, Wenju Lu, Xinlu Wang and Tao Wang Tags: Research Source Type: research
Differentiating interstitial lung diseases from other respiratory diseases using electronic nose technology
Interstitial lung disease (ILD) may be difficult to distinguish from other respiratory diseases due to overlapping clinical presentation. Recognition of ILD is often late, causing delay which has been associat... (Source: Respiratory Research)
Source: Respiratory Research - November 6, 2023 Category: Respiratory Medicine Authors: Iris G. van der Sar, Marlies S. Wijsenbeek, Gert-Jan Braunstahl, Jason O. Loekabino, Anne-Marie C. Dingemans, Johannes C. C. M. In ‘t Veen and Catharina C. Moor Tags: Research Source Type: research
Plasma metabolomics and quantitative interstitial abnormalities in ever-smokers
Quantitative interstitial abnormalities (QIA) are an automated computed tomography (CT) finding of early parenchymal lung disease, associated with worse lung function, reduced exercise capacity, increased resp... (Source: Respiratory Research)
Source: Respiratory Research - November 4, 2023 Category: Respiratory Medicine Authors: Bina Choi, Ra úl San José Estépar, Suneeta Godbole, Jeffrey L. Curtis, Jennifer M. Wang, Rubén San José Estépar, Ivan O. Rosas, Jared R. Mayers, Brian D. Hobbs, Craig P. Hersh, Samuel Y. Ash, MeiLan K. Han, Russell P. Bowler, Kathleen A. Stringer, G Tags: Research Source Type: research
Correction to: Cigarette smoke exposed airway epithelial cells-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency
(Source: Respiratory Research)
Source: Respiratory Research - November 4, 2023 Category: Respiratory Medicine Authors: Nazli Khodayari, Regina Oshins, Borna Mehrad, Jorge E Lascano, Xiao Qiang, Jesse R West, L Shannon Holliday, Jungnam Lee, Gayle Wiesemann, Soroush Eydgahi and Mark Brantly Tags: Correction Source Type: research
Human airway tuft cells influence the mucociliary clearance through cholinergic signalling
Airway tuft cells, formerly called brush cells have long been described only morphologically in human airways. More recent RNAseq studies described a chemosensory cell population, which includes tuft cells, by... (Source: Respiratory Research)
Source: Respiratory Research - November 4, 2023 Category: Respiratory Medicine Authors: Monika I. Hollenhorst, Thomas Husnik, Malin Zylka, Nele Duda, Veit Flockerzi, Thomas Tschernig, Stephan Maxeiner and Gabriela Krasteva-Christ Tags: Research Source Type: research
Differential airway resistome and its correlations with clinical characteristics in Haemophilus- or Pseudomonas-predominant microbial subtypes of bronchiectasis
The prevalence and clinical correlates of antibiotic resistance genes (ARGs) in bronchiectasis are not entirely clear. We aimed to profile the ARGs in sputum from adults with bronchiectasis, and explore the as... (Source: Respiratory Research)
Source: Respiratory Research - November 2, 2023 Category: Respiratory Medicine Authors: Xin-zhu Yi, Jun-hao Yang, Yan Huang, Xiao-rong Han, Hui-min Li, Lai-jian Cen, Zhen-hong Lin, Cui-xia Pan, Zhang Wang and Wei-jie Guan Tags: Research Source Type: research
Prostaglandin and prostaglandin receptors: present and future promising therapeutic targets for pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH), Group 1 pulmonary hypertension (PH), is a type of pulmonary vascular disease characterized by abnormal contraction and remodeling of the pulmonary arterioles, manifested ... (Source: Respiratory Research)
Source: Respiratory Research - November 1, 2023 Category: Respiratory Medicine Authors: Cheng Zeng, Jing Liu, Xialei Zheng, Xinqun Hu and Yuhu He Tags: Review Source Type: research
Do alternative tobacco products induce less adverse respiratory risk than cigarettes?
Due to the relatively short existence of alternative tobacco products, gaps exist in our current understanding of their long-term respiratory health effects. We therefore undertook the first-ever side-by-side ... (Source: Respiratory Research)
Source: Respiratory Research - October 31, 2023 Category: Respiratory Medicine Authors: Tariq A. Bhat, Suresh G. Kalathil, Noel Leigh, Alan Hutson, Maciej L. Goniewicz and Yasmin M. Thanavala Tags: Research Source Type: research
Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways
The standard therapy for bronchial asthma consists of combinations of acute (short-acting ß2-sympathomimetics) and, depending on the severity of disease, additional long-term treatment (including inhaled glucocor... (Source: Respiratory Research)
Source: Respiratory Research - October 31, 2023 Category: Respiratory Medicine Authors: Paulina Hempel, Virag Klein, Anna Michely, Svenja B öll, Annette D. Rieg, Jan Spillner, Till Braunschweig, Saskia von Stillfried, Norbert Wagner, Christian Martin, Klaus Tenbrock and Eva Verjans Tags: Research Source Type: research
Exogenous IL-25 ameliorates airway neutrophilia via suppressing macrophage M1 polarization and the expression of IL-12 and IL-23 in asthma
Severe asthma is associated with substantial mortality and has unmet therapeutic need. A subset of severe asthma is characterized by neutrophilic airway inflammation. Classically activated (or M1) macrophages ... (Source: Respiratory Research)
Source: Respiratory Research - October 28, 2023 Category: Respiratory Medicine Authors: Chenli Chang, Gongqi Chen, Wenliang Wu, Dian Chen, Shengchong Chen, Jiali Gao, Yuchen Feng and Guohua Zhen Tags: Research Source Type: research
Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study
The diaphragm function assessed by ultrasound has been well-studied in COPD, asthma, and intensive care. However, there are only a few studies on diffuse interstitial lung disease, while dyspnea and quality of... (Source: Respiratory Research)
Source: Respiratory Research - October 28, 2023 Category: Respiratory Medicine Authors: Jules Milesi, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, St éphane Delliaux, Fabienne Bregeon and Benjamin Coiffard Tags: Study Protocol Source Type: research
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma
Emerging evidence indicates that circular RNAs (circRNAs) play vital roles in tumor progression, including lung adenocarcinomas (LUAD). However, the mechanisms by which circRNAs promote the progression of LUAD... (Source: Respiratory Research)
Source: Respiratory Research - October 25, 2023 Category: Respiratory Medicine Authors: Haoran Li, Haifa Guo, Qi Huang, Shaodong Wang, Xiao Li and Mantang Qiu Tags: Research Source Type: research
Silencing of CD147 inhibits cell proliferation, migration, invasion, lipid metabolism dysregulation and promotes apoptosis in lung adenocarcinoma via blocking the Rap1 signaling pathway
This study aims to explore the specific function of CD147 in lung adenocarcinoma (LUAD) and to reveal related downstr... (Source: Respiratory Research)
Source: Respiratory Research - October 25, 2023 Category: Respiratory Medicine Authors: Ning Zhang, Zhouzhong Liu, Xuwang Lai, Shubin Liu and Yuli Wang Tags: Research Source Type: research
Usefulness of FAP α assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic pulmonary fibrosis
Fibroblast activation protein- α (FAPα) is a marker of activated fibroblasts that can be selectively targeted by an inhibitor (FAPI) and visualised by PET/CT imaging. We evaluated whether the measurement of FAP... (Source: Respiratory Research)
Source: Respiratory Research - October 25, 2023 Category: Respiratory Medicine Authors: Philom ène Lavis, Julien Pingitore, Gilles Doumont, Ani Garabet, Gaetan Van Simaeys, Simon Lacroix, Nicolas Passon, Christophe Van Heymbeek, Coraline De Maeseneire, Justine Allard, Amandine Collin, François Huaux, Christine Decaestecker, Isabelle Salmon Tags: Research Source Type: research
Mechanical thrombectomy in intermediate- and high-risk acute pulmonary embolism: hemodynamic outcomes at three months
Mechanical thrombectomy has been shown to reduce thrombus burden and pulmonary artery pressure (PAP) and to improve right ventricular (RV) function in patients with high-risk or intermediate-high-risk pulmonar... (Source: Respiratory Research)
Source: Respiratory Research - October 25, 2023 Category: Respiratory Medicine Authors: Lucas Lauder, Patricia P érez Navarro, Felix Götzinger, Sebastian Ewen, Hussam Al Ghorani, Bernhard Haring, Philipp M. Lepper, Saarraaken Kulenthiran, Michael Böhm, Andreas Link, Bruno Scheller and Felix Mahfoud Tags: Research Source Type: research
