Exogenous IL-25 ameliorates airway neutrophilia via suppressing macrophage M1 polarization and the expression of IL-12 and IL-23 in asthma

Severe asthma is associated with substantial mortality and has unmet therapeutic need. A subset of severe asthma is characterized by neutrophilic airway inflammation. Classically activated (or M1) macrophages ...

Source: Respiratory Research - October 28, 2023 Category: Respiratory Medicine Authors: Chenli Chang, Gongqi Chen, Wenliang Wu, Dian Chen, Shengchong Chen, Jiali Gao, Yuchen Feng and Guohua Zhen Tags: Research Source Type: research