A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema
No single pulmonary function test captures the functional effect of emphysema in idiopathic pulmonary fibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. H... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Athol U. Wells, Joseph Jacob, Nicola Sverzellati, Gary Cross, Joseph Barnett, Angelo De Lauretis, Katerina Antoniou, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler and Vincent Cottin Tags: Research Source Type: research

Hospitalized acute exacerbation in chronic obstructive pulmonary disease – impact on long-term renal outcomes
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common and preventable event in patients with chronic obstructive pulmonary disease (COPD). Data regarding the impact of AECOPD on shor... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Wang Chun Kwok, Terence C. C. Tam, James C. M. Ho, David C. L. Lam, Mary S. M. Ip and Desmond Y. H. Yap Tags: Research Source Type: research

Remotely supervised spirometry versus laboratory-based spirometry during the COVID-19 pandemic: a retrospective analysis
The COVID-19 pandemic has constrained access to spirometry, and the inherent risk of infectious transmission during aerosol-generating procedures has necessitated the rapid development of Remotely Supervised S... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Łukasz Kołtowski, Mikołaj Basza, Wojciech Bojanowicz, Piotr Dąbrowiecki, Mateusz Soliński, Katarzyna Górska, Piotr Korczyński and Lauren E. Eggert Tags: Research Source Type: research

Phenotypic subtypes of fibrotic hypersensitivity pneumonitis identified by machine learning consensus clustering analysis
Patients with fibrotic hypersensitivity pneumonitis (f-HP) have varied clinical and radiologic presentations whose associated phenotypic outcomes have not been previously described. We conducted a study to eva... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Tananchai Petnak, Wisit Cheungpasitporn, Charat Thongprayoon, Tulaton Sodsri, Supawit Tangpanithandee and Teng Moua Tags: Research Source Type: research

Eligibility of patients with chronic obstructive pulmonary disease for inclusion in randomised control trials investigating triple therapy: a study using routinely collected data
We described the proportion of people with chronic obstructive pulmonary ... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Hannah R. Whittaker, Aria Torkpour and Jennifer Quint Tags: Research Source Type: research

Advancing accuracy in breath testing for lung cancer: strategies for improving diagnostic precision in imbalanced data
Breath testing using an electronic nose has been recognized as a promising new technique for the early detection of lung cancer. Imbalanced data are commonly observed in electronic nose studies, but methods to... (Source: Respiratory Research)
Source: Respiratory Research - January 16, 2024 Category: Respiratory Medicine Authors: Ke-Cheng Chen, Shuenn-Wen Kuo, Ruei-Hao Shie and Hsiao-Yu Yang Tags: Research Source Type: research

Identification of kynurenine and quinolinic acid as promising serum biomarkers for drug-induced interstitial lung diseases
Drug-induced interstitial lung disease (DILD) is a lung injury caused by various types of drugs and is a serious problem in both clinical practice and drug development. Clinical management of the condition wou... (Source: Respiratory Research)
Source: Respiratory Research - January 14, 2024 Category: Respiratory Medicine Authors: Yuchen Sun, Kosuke Saito, Atsuhito Ushiki, Mitsuhiro Abe, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Kazuhisa Takemoto, Rika Ishikawa, Toshiko Momiyama, Shin-ichiro Matsuyama, Nori Tags: Research Source Type: research

Microbes little helpers and suppliers for therapeutic asthma approaches
Bronchial asthma is a prevalent and increasingly chronic inflammatory lung disease affecting over 300 million people globally. Initially considered an allergic disorder driven by mast cells and eosinophils, as... (Source: Respiratory Research)
Source: Respiratory Research - January 13, 2024 Category: Respiratory Medicine Authors: Sebastian Reuter, Jonas Raspe and Christian Taube Tags: Review Source Type: research

Signaling pathways and potential therapeutic targets in acute respiratory distress syndrome (ARDS)
Acute respiratory distress syndrome (ARDS) is a common condition associated with critically ill patients, characterized by bilateral chest radiographical opacities with refractory hypoxemia due to noncardiogen... (Source: Respiratory Research)
Source: Respiratory Research - January 13, 2024 Category: Respiratory Medicine Authors: Qianrui Huang, Yue Le, Shusheng Li and Yi Bian Tags: Review Source Type: research

Airway disease decreases the therapeutic potential of epithelial stem cells
Tissue-engineered tracheal grafts (TETG) can be recellularized by the host or pre-seeded with host-derived cells. However, the impact of airway disease on the recellularization process is unknown. (Source: Respiratory Research)
Source: Respiratory Research - January 12, 2024 Category: Respiratory Medicine Authors: Lisa Zhang, Natalie Kelly, Kimberly M Shontz, Cynthia L. Hill, Jacob T. Stack, Jazmin Calyeca, Laura Matrka, Audrey Miller, Susan D Reynolds and Tendy Chiang Tags: Research Source Type: research

Hemoadsorption in acute respiratory distress syndrome patients requiring venovenous extracorporeal membrane oxygenation: a systematic review
Venovenous extracorporeal membrane oxygenation (VV ECMO) has been widely used for severe acute respiratory distress syndrome (ARDS) in recent years. However, the role of hemoadsorption in ARDS patients requiri... (Source: Respiratory Research)
Source: Respiratory Research - January 12, 2024 Category: Respiratory Medicine Authors: Wenli Li, Yuansen Chen, Duo Li, Xiangyan Meng, Ziquan Liu, Yanqing Liu and Haojun Fan Tags: Review Source Type: research

Tobacco and menthol flavored nicotine-free electronic cigarettes induced inflammation and dysregulated repair in lung fibroblast and epithelium
Electronic cigarette (e-cig) vaping has increased in the past decade in the US, and e-cig use is misleadingly marketed as a safe cessation for quitting smoking. The main constituents in e-liquid are humectants... (Source: Respiratory Research)
Source: Respiratory Research - January 10, 2024 Category: Respiratory Medicine Authors: Qixin Wang, Joseph H Lucas, Cortney Pang, Ruogang Zhao and Irfan Rahman Tags: Research Source Type: research

Artificial intelligence-based analysis of the spatial distribution of abnormal computed tomography patterns in SARS-CoV-2 pneumonia: association with disease severity
The substantial heterogeneity of clinical presentations in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia still requires robust chest computed tomography analysis to ident... (Source: Respiratory Research)
Source: Respiratory Research - January 10, 2024 Category: Respiratory Medicine Authors: Yusuke Kataoka, Naoya Tanabe, Masahiro Shirata, Nobuyoshi Hamao, Issei Oi, Tomoki Maetani, Yusuke Shiraishi, Kentaro Hashimoto, Masatoshi Yamazoe, Hiroshi Shima, Hitomi Ajimizu, Tsuyoshi Oguma, Masahito Emura, Kazuo Endo, Yoshinori Hasegawa, Tadashi Mio & Tags: Research Source Type: research

Pan-cancer assessment of antineoplastic therapy-induced interstitial lung disease in patients receiving subsequent therapy immediately following immune checkpoint blockade therapy
Drug-induced interstitial lung disease (DIILD) is a serious adverse event potentially induced by any antineoplastic agent. Whether cancer patients are predisposed to a higher risk of DIILD after receiving immu... (Source: Respiratory Research)
Source: Respiratory Research - January 10, 2024 Category: Respiratory Medicine Authors: Yoshihiro Kitahara, Yusuke Inoue, Hideki Yasui, Masato Karayama, Yuzo Suzuki, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Kazuhito Funai, Tetsuya Honda, Kiyoshi Misawa, Hideaki Miyake, Hiroya Takeuchi, Naoki Inui and Takafumi Su Tags: Research Source Type: research

The use of cultured human alveolar basal cells to mimic honeycomb formation in idiopathic pulmonary fibrosis
Honeycomb cysts (HC) within the alveolar region are distinct histopathological features in the lungs of idiopathic pulmonary fibrosis (IPF) patients. HC are lined with a single-or stratified layer of basal cel... (Source: Respiratory Research)
Source: Respiratory Research - January 10, 2024 Category: Respiratory Medicine Authors: Sabrina Blumer, Petra Khan, Nataliia Artysh, Linda Plappert, Spasenija Savic, Lars Knudsen, Danny Jonigk, Mark P. Kuehnel, Antje  Prasse and Katrin E. Hostettler Tags: Research Source Type: research