The airway neuro-immune axis as a therapeutic target in allergic airway diseases
Recent evidence has increasingly underscored the importance of the neuro-immune axis in mediating allergic airway diseases, such as allergic asthma and allergic rhinitis. The intimate spatial relationship betw... (Source: Respiratory Research)
Source: Respiratory Research - February 8, 2024 Category: Respiratory Medicine Authors: Wanhua Wu, Jianing Li, Su Chen and Suidong Ouyang Tags: Review Source Type: research

The role of extracellular vesicles in COPD and potential clinical value
Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease and a major health burden worldwide. Extracellular vesicles (EVs) are nanosized vesicles which possess a lipid bilayer structure tha... (Source: Respiratory Research)
Source: Respiratory Research - February 8, 2024 Category: Respiratory Medicine Authors: Shasha Liu, Xiaowu Tan and Sha Liu Tags: Review Source Type: research

Elevated pulmonary vascular resistance is associated with increased lung transplant waitlist mortality among patients with chronic obstructive pulmonary disease and pulmonary hypertension: a retrospective cohort analysis
The latest European Society of Cardiology and European Respiratory Society guidelines have changed the definition of both pre-capillary pulmonary hypertension (PH) and severe PH in chronic lung disease. The cl... (Source: Respiratory Research)
Source: Respiratory Research - February 7, 2024 Category: Respiratory Medicine Authors: Shameek K. Gayen, Mary Zulty and Gerard J. Criner Tags: Research Source Type: research

Retraction Note: Protective role of p120-catenin in maintaining the integrity of adherens and tight junctions in ventilator-induced lung injury
(Source: Respiratory Research)
Source: Respiratory Research - February 7, 2024 Category: Respiratory Medicine Authors: Changping Gu, Mengjie Liu, Tao Zhao, Dong Wang and Yuelan Wang Tags: Retraction Note Source Type: research

Circular RNAs and their roles in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited treatment options. Circular RNAs (circRNAs) have emerged as a novel class of non-coding RNAs with diverse functions in c... (Source: Respiratory Research)
Source: Respiratory Research - February 6, 2024 Category: Respiratory Medicine Authors: Akshaya Surendran, Chaoqun Huang and Lin Liu Tags: Review Source Type: research

Interstitial lung abnormality evaluated by an automated quantification system: prevalence and progression rate
Despite the importance of recognizing interstitial lung abnormalities, screening methods using computer-based quantitative analysis are not well developed, and studies on the subject with an Asian population a... (Source: Respiratory Research)
Source: Respiratory Research - February 6, 2024 Category: Respiratory Medicine Authors: Ju Hyun Oh, Grace Hyun J. Kim and Jin Woo Song Tags: Research Source Type: research

Using cryoprobes of different sizes combined with cone-beam computed tomography-derived augmented fluoroscopy and endobronchial ultrasound to diagnose peripheral pulmonary lesions: a propensity-matched study
Endobronchial ultrasound (EBUS) and cone-beam computed tomography-derived augmented fluoroscopy (CBCT-AF) are utilized for the diagnosis of peripheral pulmonary lesions (PPLs). Combining them with transbronchi... (Source: Respiratory Research)
Source: Respiratory Research - February 5, 2024 Category: Respiratory Medicine Authors: Ching-Kai Lin, Sheng-Yuan Ruan, Hung-Jen Fan, Hao-Chun Chang, Yen-Ting Lin and Chao-Chi Ho Tags: Research Source Type: research

MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
Chronic obstructive pulmonary disease (COPD) is a leading aging related cause of global mortality. Small airway narrowing is recognized as an early and significant factor for COPD development. Senescent fibrob... (Source: Respiratory Research)
Source: Respiratory Research - February 5, 2024 Category: Respiratory Medicine Authors: Fang Lu, Li-peng Yao, Dan-dan Gao, Tahereh Alinejad, Xin-qing Jiang, Qi Wu, Qiao-cheng Zhai, Ming Liu, Sheng-mei Zhu, Mao-xiang Qian, Li-feng Xu, Cheng-shui Chen and Feng Zhang Tags: Research Source Type: research

Role of multidrug-resistant bacteria in weaning from invasive mechanical ventilation
Although multidrug-resistant bacteria (MDR) are common in patients undergoing prolonged weaning, there is little data on their impact on weaning and patient outcomes. (Source: Respiratory Research)
Source: Respiratory Research - February 5, 2024 Category: Respiratory Medicine Authors: Julia D. Michels-Zetsche, Vicky Gassmann, Jasmin K. Jasuja, Benjamin Neetz, Philipp H öger, Jan Meis, Simone Britsch, Urte Sommerwerck, Sebastian Fähndrich, Florian Bornitz, Michael M. Müller, Felix J.F. Herth and Franziska C. Trudzinski Tags: Research Source Type: research

Viral coinfection in hospitalized patients during the COVID-19 pandemic in Southern Brazil: a retrospective cohort study
Since the worldwide spread of SARS-CoV-2, different strategies have been followed to combat the pandemic and limit virus transmission. In the meantime, other respiratory viruses continued to circulate, though ... (Source: Respiratory Research)
Source: Respiratory Research - February 5, 2024 Category: Respiratory Medicine Authors: Jaqueline Rhoden, Andressa Ta íz Hoffmann, Janaína Franciele Stein, Bruna Seixas da Rocha, Vinícius Monteagudo de Barros, Eduardo Viegas da Silva, Juliane Deise Fleck and Caroline Rigotto Tags: Research Source Type: research

Impact of ambient temperature on respiratory disease: a case-crossover study in Seoul
Respiratory diseases contribute to global morbidity and mortality, and temperature is a significant factor. We investigated the association between ambient temperature and emergency department (ED) visits for ... (Source: Respiratory Research)
Source: Respiratory Research - February 5, 2024 Category: Respiratory Medicine Authors: Hyewon Lee and Hee-Young Yoon Tags: Research Source Type: research

Upregulated microRNA-125b-5p in patients with asthma-COPD overlap mediates oxidative stress and late apoptosis via targeting IL6R/TRIAP1 signaling
Among patients with chronic obstructive pulmonary disease (COPD), some have features of both asthma and COPD —a condition categorized as asthma-COPD overlap (ACO). Our aim was to determine whether asthma- or CO... (Source: Respiratory Research)
Source: Respiratory Research - February 1, 2024 Category: Respiratory Medicine Authors: Yu-Ping Chang, Yi-Hsuan Tsai, Yu-Mu Chen, Kuo-Tung Huang, Chiu-Ping Lee, Po-Yuan Hsu, Hung-Chen Chen, Meng-Chih Lin and Yung-Che Chen Tags: Research Source Type: research

Role and intervention of PAD4 in NETs in acute respiratory distress syndrome
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Acute respiratory distress syndrome (ARDS) is a common sepsis-associated injury that can increase postoperative... (Source: Respiratory Research)
Source: Respiratory Research - January 30, 2024 Category: Respiratory Medicine Authors: Xiaojie Liu, Tianjun Li, Huailong Chen, Li Yuan and Hushan Ao Tags: Review Source Type: research

Circ-phkb promotes cell apoptosis and inflammation in LPS-induced alveolar macrophages via the TLR4/MyD88/NF-kB/CCL2 axis
Circular RNAs (CircRNAs) have been associated with acute lung injury (ALI), but their molecular mechanisms remain unclear. (Source: Respiratory Research)
Source: Respiratory Research - January 29, 2024 Category: Respiratory Medicine Authors: Xuxia Wei, Xiaomeng Yi, Jianrong Liu, Xin Sui, Lijuan Li, Mei Li, Haijin Lv and Huimin Yi Tags: Research Source Type: research

Risk factors for long-term invasive mechanical ventilation: a longitudinal study using German health claims data
Long-term invasive mechanical ventilation (IMV) is a major burden for those affected and causes high costs for the health care system. Early risk assessment is a prerequisite for the best possible support of h... (Source: Respiratory Research)
Source: Respiratory Research - January 27, 2024 Category: Respiratory Medicine Authors: Franziska C. Trudzinski, Julia D. Michels-Zetsche, Benjamin Neetz, Jan Meis, Michael M üller, Axel Kempa, Claus Neurohr, Armin Schneider, Felix J. F. Herth, Joachim Szecsenyi, Elena Biehler, Thomas Fleischauer, Michel Wensing, Simone Britsch, Janina Schu Tags: Research Source Type: research