Local heterogeneity of normal lung parenchyma and small airways disease are associated with COPD severity and progression
Small airways disease (SAD) is a major cause of airflow obstruction in COPD patients and has been identified as a precursor to emphysema. Although the amount of SAD in the lungs can be quantified using our Par... (Source: Respiratory Research)
Source: Respiratory Research - February 28, 2024 Category: Respiratory Medicine Authors: Alexander J. Bell, Ravi Pal, Wassim W. Labaki, Benjamin A. Hoff, Jennifer M. Wang, Susan Murray, Ella A. Kazerooni, Stefanie Galban, David A. Lynch, Stephen M. Humphries, Fernando J. Martinez, Charles R. Hatt, MeiLan K. Han, Sundaresh Ram and Craig J. Gal Tags: Research Source Type: research
FGF18 alleviates sepsis-induced acute lung injury by inhibiting the NF- κB pathway
Acute lung injury (ALI) is a devastating clinical disorder with a high mortality rate, and there is an urgent need for more effective therapies. Fibroblast growth factor 18 (FGF18) has potent anti-inflammatory... (Source: Respiratory Research)
Source: Respiratory Research - February 28, 2024 Category: Respiratory Medicine Authors: Zhenyu Hu, Jindan Dai, Tianpeng Xu, Hui Chen, Guoxiu Shen, Jie Zhou, Hongfang Ma, Yang Wang and Litai Jin Tags: Research Source Type: research
Psoriasis may increase the risk of idiopathic pulmonary fibrosis: a two-sample Mendelian randomization study
Although some studies have indicated that Psoriasis could contribute to the risk of idiopathic pulmonary fibrosis (IPF), no study has reported a clear causal association between them. Our aim was to explore th... (Source: Respiratory Research)
Source: Respiratory Research - February 26, 2024 Category: Respiratory Medicine Authors: Lingli Chen, Yujie Wei, Mengjin Hu, Yile Liu and Xiangrong Zheng Tags: Research Source Type: research
Intra-breath changes in respiratory mechanics are sensitive to history of respiratory illness in preschool children: the SEPAGES cohort
Intra-breath oscillometry has been proposed as a sensitive means of detecting airway obstruction in young children. We aimed to assess the impact of early life wheezing and lower respiratory tract illness on l... (Source: Respiratory Research)
Source: Respiratory Research - February 24, 2024 Category: Respiratory Medicine Authors: Val érie Siroux, Anne Boudier, Sarah Lyon-Caen, Joane Quentin, Yoann Gioria, Zoltán Hantos, Rémy Slama, Isabelle Pin and Sam Bayat Tags: Research Source Type: research
Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) as common life-threatening lung diseases with high mortality rates are mostly associated with acute and severe infla... (Source: Respiratory Research)
Source: Respiratory Research - February 24, 2024 Category: Respiratory Medicine Authors: Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu and Zhenshun Cheng Tags: Research Source Type: research
Correction to: Association between cigar use, with and without cigarettes, and incident diagnosed COPD: a longitudinal cohort study
(Source: Respiratory Research)
Source: Respiratory Research - February 23, 2024 Category: Respiratory Medicine Authors: Steven Cook, James H. Buszkiewicz, David T. Levy, Rafael Meza and Nancy L. Fleischer Tags: Correction Source Type: research
Atorvastatin for reduction of 28-day mortality in severe and critical COVID-19 patients: a randomized controlled trial
COVID-19 is an abnormal host response to the SARS-CoV-2 infection, which is associated with endothelial dysfunction and multi-organ failure. Atorvastatin has been proposed to reduce COVID-19 severity and morta... (Source: Respiratory Research)
Source: Respiratory Research - February 22, 2024 Category: Respiratory Medicine Authors: Naglaa Hamdi Eltahan, Neamat Hamdy Elsawy, Kholoud M. Abdelaaty, Amal Salah Elhamaky, Ahmed H. Hassan and Moataz Maher Emara Tags: Research Source Type: research
Impact of preexisting interstitial lung disease on mortality in COVID-19 patients from the early pandemic to the delta variant epidemic: a nationwide population-based study
COVID-19 patients with preexisting interstitial lung disease (ILD) were reported to have a high mortality rate; however, this was based on data from the early stages of the pandemic. It is uncertain how their ... (Source: Respiratory Research)
Source: Respiratory Research - February 21, 2024 Category: Respiratory Medicine Authors: Koichi Miyashita, Hironao Hozumi, Kazuki Furuhashi, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Toshiyuki Ojima and Takafumi Suda Tags: Research Source Type: research
Distinct impacts of radiological appearance on lymph node metastasis and prognosis based on solid size in clinical T1 non-small cell lung cancer
This study aimed to evaluate the specific impacts of nodule radiological appearance (SN vs. PSN) on lymph n... (Source: Respiratory Research)
Source: Respiratory Research - February 21, 2024 Category: Respiratory Medicine Authors: Zhihua Li, Cheng Pan, Wenzheng Xu, Chen Zhao, Xianglong Pan, Zhibo Wang, Weibing Wu and Liang Chen Tags: Research Source Type: research
Assessing the acceptability and feasibility of remote spirometric monitoring for rural patients with interstitial lung disease: a multimethod approach
Interstitial lung disease encompasses a group of rare lung conditions causing inflammation and scarring of lung tissue. The typical method of monitoring disease activity is through pulmonary function tests per... (Source: Respiratory Research)
Source: Respiratory Research - February 20, 2024 Category: Respiratory Medicine Authors: Ryan D. Boente, Sydney Schacht, Rebecca Borton, Joseph Vincent, Lilian Golzarri-Arroyo and Nicholas Rattray Tags: Research Source Type: research
MiR-23a-5p alleviates chronic obstructive pulmonary disease through targeted regulation of RAGE-ROS pathway
This study aimed to investigate miRNA regulation of Receptor for Advanced... (Source: Respiratory Research)
Source: Respiratory Research - February 20, 2024 Category: Respiratory Medicine Authors: Chenli Chang, Ke Huang, Xia Xu, Ruirui Duan, Tao Yu, Xu Chu, Chen Chen, Baicun Li and Ting Yang Tags: Research Source Type: research
Causal relationships of metabolites with allergic diseases: a trans-ethnic Mendelian randomization study
This study ... (Source: Respiratory Research)
Source: Respiratory Research - February 20, 2024 Category: Respiratory Medicine Authors: Junhao Tu, Jinyang Wen, Qing Luo, Xin Li, Deyun Wang and Jing Ye Tags: Research Source Type: research
Association of blood cadmium concentration with chronic obstructive pulmonary disease progression: a prospective cohort study
Prior studies in patients with chronic obstructive pulmonary disease (COPD) had indicated a potential correlation between cadmium (Cd) exposure and reduction in lung function. Nevertheless, the influence of Cd... (Source: Respiratory Research)
Source: Respiratory Research - February 17, 2024 Category: Respiratory Medicine Authors: Jing Sun, You-Peng Deng, Juan Xu, Feng-Min Zhu, Qi-Yuan He, Min-Min Tang, Ying Liu, Jin Yang, Hong-Yan Liu, Lin Fu and Hui Zhao Tags: Research Source Type: research
Fine particulate matter 2.5 induces susceptibility to Pseudomonas aeruginosa infection via expansion of PD-L1high neutrophils in mice
Exposure to PM2.5 has been implicated in a range of detrimental health effects, particularly affecting the respiratory system. However, the precise underlying mechanisms remain elusive. (Source: Respiratory Research)
Source: Respiratory Research - February 14, 2024 Category: Respiratory Medicine Authors: Li Luo, Manling Jiang, Ying Xiong, Anying Xiong, Lei Zhang, Dehong Wu, Yao Liu, Qin Ran, Jiliu Liu, Yi Zhang, Jiahuan Li, Xiang He, Junyi Wang and Guoping Li Tags: Research Source Type: research
A simple clinical risk score (ABCDMP) for predicting mortality in patients with AECOPD and cardiovascular diseases
The morbidity and mortality among hospital inpatients with AECOPD and CVDs remains unacceptably high. Currently, no risk score for predicting mortality has been specifically developed in patients with AECOPD a... (Source: Respiratory Research)
Source: Respiratory Research - February 10, 2024 Category: Respiratory Medicine Authors: Jiarui Zhang, Qun Yi, Chen Zhou, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Jianchu Zhang, Xianhua Li, Xiufang Xie, Pinhua Pan, Mengqiu Yi, Lina Cheng, Hui Zhou, Liang Liu, Adila Aili & hellip; Tags: Research Source Type: research
