Blood FOLR3 methylation dysregulations and heterogeneity in non-small lung cancer highlight its strong associations with lung squamous carcinoma
Non-small cell lung cancer (NSCLC) accounts for the vast majority of lung cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA methylation occurs early during carcinogenesi... (Source: Respiratory Research)
Source: Respiratory Research - January 25, 2024 Category: Respiratory Medicine Authors: Yunhui Qu, Xiuzhi Zhang, Rong Qiao, Feifei Di, Yakang Song, Jun Wang, Longtao Ji, Jie Zhang, Wanjian Gu, Yifei Fang, Baohui Han, Rongxi Yang, Liping Dai and Songyun Ouyang Tags: Research Source Type: research

Retraction Note: Activation of c-Src tyrosine kinase mediated the degradation of occludin in ventilator-induced lung injury
(Source: Respiratory Research)
Source: Respiratory Research - January 24, 2024 Category: Respiratory Medicine Authors: Tao Zhao, Mengjie Liu, Changping Gu, Xin Wang and Yuelan Wang Tags: Retraction Note Source Type: research

Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD —results from COSYCONET
MRproANP and COPAVP are prognostic markers for mortality in chronic obstructive pulmonary disease (COPD). Furthermore, these biomarkers predict mortality due to cardiovascular diseases, which are important pro... (Source: Respiratory Research)
Source: Respiratory Research - January 24, 2024 Category: Respiratory Medicine Authors: S. F ähndrich, C. Herr, S. Teuteberg, P. Alter, S. Söhler, D. Soriano, J. Classen, J. Adams, V. Weinhold, H. Watz, B. Waschki, T. Zeller, M. Eichenlaub, F. C. Trudzinski, J. D. Michels, A. Omlor & hellip; Tags: Research Source Type: research

Tobacco-derived and tobacco-free nicotine cause differential inflammatory cell influx and MMP-9 in mouse lung
Electronic nicotine delivery systems (ENDS) or electronic cigarettes (e-cigarettes) aerosolize an e-liquid composed of propylene glycol (PG) and vegetable glycerin (VG) as humectants, flavoring chemicals, and ... (Source: Respiratory Research)
Source: Respiratory Research - January 23, 2024 Category: Respiratory Medicine Authors: Thomas Lamb, Gagandeep Kaur and Irfan Rahman Tags: Research Source Type: research

Mucus plugs in the airways of asthmatic subjects and smoking status
Mucus plugs have been described in the airways of asthmatic subjects, particularly those with associated with type 2 inflammation and sputum eosinophilia. In the current study we addressed the question of whet... (Source: Respiratory Research)
Source: Respiratory Research - January 23, 2024 Category: Respiratory Medicine Authors: Camille Audousset, Sana Swaleh, Ron Olivenstein, Motahareh Vameghestahbanati, Miranda Kirby, Alexandre Semionov, Benjamin M. Smith and James G. Martin Tags: Research Source Type: research

Diagnostic accuracy of thoracic CT to differentiate transudative from exudative pleural effusion prior to thoracentesis
Computed tomography (CT) scan is commonly performed for pleural effusion diagnostis in the clinic. However, there are limited data assessing the accuracy of thoracic CT for the separation of transudative from ... (Source: Respiratory Research)
Source: Respiratory Research - January 23, 2024 Category: Respiratory Medicine Authors: Yan Zhang, Yang Zhang, Wei Wang, Xiaoyu Feng, Jiahuan Guo, Bo Chen, Fuyun Zhang, Huanhuan Wang, Mengnan Fan, Yingwei Zhu, Yuxia Sun, Tongsheng Wang, Yimin Mao and Pengfei Gao Tags: Research Source Type: research

Blood glucose and lipids are associated with sarcoidosis: findings from observational and mendelian randomization studies
Several researches have demonstrated that patients with sarcoidosis accompanied with the abnormality in blood glucose and/or lipids, however, the causal relationship between them remains uncertain. To elucidat... (Source: Respiratory Research)
Source: Respiratory Research - January 22, 2024 Category: Respiratory Medicine Authors: Yuan Zhan, Jiaheng Zhang, Ruonan Yang, Zhesong Deng, Shanshan Chen, Jie Feng, Jixing Wu, Qian Huang, Yiya Gu and Jungang Xie Tags: Research Source Type: research

Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air –liquid interface
Chronic obstructive pulmonary disease (COPD) has the highest increased risk due to household air pollution arising from biomass fuel burning. However, knowledge on COPD patho-mechanisms is mainly limited to to... (Source: Respiratory Research)
Source: Respiratory Research - January 20, 2024 Category: Respiratory Medicine Authors: Swapna Upadhyay, Mizanur Rahman, Selina Rinaldi, Jeremy Koelmel, Elizabeth Z. Lin, Padukudru Anand Mahesh, Johannes Beckers, Gunnar Johanson, Krystal J. Godri Pollitt, Lena Palmberg, Martin Irmler and Koustav Ganguly Tags: Research Source Type: research

Multi-omics analysis reveals overactive inflammation and dysregulated metabolism in severe community-acquired pneumonia patients
Severe community-acquired pneumonia (S-CAP) is a public health threat, making it essential to identify novel biomarkers and investigate the underlying mechanisms of disease severity. (Source: Respiratory Research)
Source: Respiratory Research - January 19, 2024 Category: Respiratory Medicine Authors: Jieqiong Li, Yawen Wang, Weichao Zhao, Tingyu Yang, Qianyu Zhang, Huqin Yang, Xuyan Li and Zhaohui Tong Tags: Research Source Type: research

The genetic etiology of body fluids on chronic obstructive airways disease
Numerous studies have documented significant alterations in the bodily fluids of Chronic Obstructive Pulmonary Disease (COPD) patients. However, existing literature lacks causal inference due to residual confo... (Source: Respiratory Research)
Source: Respiratory Research - January 19, 2024 Category: Respiratory Medicine Authors: Zhangkai J. Cheng, Haojie Wu, Zhenglin Chang, Jiahao Cheng, Suilin Wang, Changlian Liu, Yanxi Zhang, Shiliang Xu, Qiongqiong Wan, JinWen Ron, Kemin Liu and Baoqing Sun Tags: Research Source Type: research

Malignant pleural effusion: current understanding and therapeutic approach
Malignant pleural effusion (MPE) is a common complication of thoracic and extrathoracic malignancies and is associated with high mortality and elevated costs to healthcare systems. Over the last decades the un... (Source: Respiratory Research)
Source: Respiratory Research - January 19, 2024 Category: Respiratory Medicine Authors: Francesca Gonnelli, Wafa Hassan, Martina Bonifazi, Valentina Pinelli, Eihab O Bedawi, Jos é M. Porcel, Najib M Rahman and Federico Mei Tags: Review Source Type: research

What is the actual relationship between neutrophil extracellular traps and COVID-19 severity? A longitudinal study
Neutrophil extracellular traps (NETs) have repeatedly been related to COVID-19 severity and mortality. However, there is no consensus on their quantification, and there are scarce data on their evolution durin... (Source: Respiratory Research)
Source: Respiratory Research - January 19, 2024 Category: Respiratory Medicine Authors: Cristina de Diego, Ana Bel én Lasierra, Lucía López-Vergara, Laura Torralba, Pablo Ruiz de Gopegui, Raquel Lahoz, Claudia Abadía, Javier Godino, Alberto Cebollada, Beatriz Jimeno, Carlota Bello, Antonio Tejada and Salvador Bello Tags: Research Source Type: research

A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema
No single pulmonary function test captures the functional effect of emphysema in idiopathic pulmonary fibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. H... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Athol U. Wells, Joseph Jacob, Nicola Sverzellati, Gary Cross, Joseph Barnett, Angelo De Lauretis, Katerina Antoniou, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler and Vincent Cottin Tags: Research Source Type: research

Hospitalized acute exacerbation in chronic obstructive pulmonary disease – impact on long-term renal outcomes
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common and preventable event in patients with chronic obstructive pulmonary disease (COPD). Data regarding the impact of AECOPD on shor... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Wang Chun Kwok, Terence C. C. Tam, James C. M. Ho, David C. L. Lam, Mary S. M. Ip and Desmond Y. H. Yap Tags: Research Source Type: research

Remotely supervised spirometry versus laboratory-based spirometry during the COVID-19 pandemic: a retrospective analysis
The COVID-19 pandemic has constrained access to spirometry, and the inherent risk of infectious transmission during aerosol-generating procedures has necessitated the rapid development of Remotely Supervised S... (Source: Respiratory Research)
Source: Respiratory Research - January 18, 2024 Category: Respiratory Medicine Authors: Łukasz Kołtowski, Mikołaj Basza, Wojciech Bojanowicz, Piotr Dąbrowiecki, Mateusz Soliński, Katarzyna Górska, Piotr Korczyński and Lauren E. Eggert Tags: Research Source Type: research