Effects of subchronic dietary exposure to the engineered nanomaterials SiO2 and CeO2 in C57BL/6J and 5xFAD Alzheimer model mice
There is an increasing concern about the neurotoxicity of engineered nanomaterials (NMs). To investigate the effects of subchronic oral exposures to SiO2 and CeO2 NMs on Alzheimer ’s disease (AD)-like pathology, 5... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 25, 2022 Category: Toxicology Authors: Adriana Sofranko, Tina Wahle, Julia Kolling, Harm J. Heusinkveld, Burkhard Stahlmecke, Martin Rosenbruch, Catrin Albrecht and Roel P. F. Schins Tags: Research Source Type: research
Nitrogen-doped graphene quantum dots induce ferroptosis through disrupting calcium homeostasis in microglia
Along with the wild applications of nitrogen-doped graphene quantum dots (N-GQDs) in the fields of biomedicine and neuroscience, their increasing exposure to the public and potential biosafety problem has gain... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 24, 2022 Category: Toxicology Authors: Tianshu Wu, Xinyu Wang, Jin Cheng, Xue Liang, Yimeng Li, Min Chen, Lu Kong and Meng Tang Tags: Research Source Type: research
Gut microbiome and plasma metabolome changes in rats after oral gavage of nanoparticles: sensitive indicators of possible adverse health effects
The oral uptake of nanoparticles is an important route of human exposure and requires solid models for hazard assessment. While the systemic availability is generally low, ingestion may not only affect gastroi... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 23, 2022 Category: Toxicology Authors: Robert Landsiedel, Daniela Hahn, Rainer Ossig, Sabrina Ritz, Lydia Sauer, Roland Buesen, Sascha Rehm, Wendel Wohlleben, Sibylle Groeters, Volker Strauss, Saskia Sperber, Haleluya Wami, Ulrich Dobrindt, Karola Prior, Dag Harmsen, Bennard van Ravenzwaay & h Tags: Research Source Type: research
Circulatory metabolites trigger ex vivo arterial endothelial cell dysfunction in population chronically exposed to diesel exhaust
Chronic exposure to diesel exhaust has a causal link to cardiovascular diseases in various environmental and occupational settings. Arterial endothelial cell function plays an important role in ensuring proper... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 22, 2022 Category: Toxicology Authors: Wenting Cheng, Huanhuan Pang, Matthew J. Campen, Jianzhong Zhang, Yanting Li, Jinling Gao, Dunqiang Ren, Xiaoya Ji, Nathaniel Rothman, Qing Lan, Yuxin Zheng, Shuguang Leng, Zeping Hu and Jinglong Tang Tags: Research Source Type: research
Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils
Cellulose nanofibrils (CNFs) have emerged as a sustainable and environmentally friendly option for a broad range of applications. The fibrous nature and high biopersistence of CNFs call for a thorough toxicity... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 16, 2022 Category: Toxicology Authors: Kukka Aimonen, Monireh Imani, Mira Hartikainen, Satu Suhonen, Esa Vanhala, Carlos Moreno, Orlando J. Rojas, Hannu Norppa and Julia Catal án Tags: Research Source Type: research
Nano-titanium dioxide inhalation exposure during gestation drives redox dysregulation and vascular dysfunction across generations
Pregnancy is associated with many rapid biological adaptations that support healthy development of the growing fetus. One of which is critical to fetal health and development is the coordination between matern... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 9, 2022 Category: Toxicology Authors: Elizabeth C. Bowdridge, Evan DeVallance, Krista L. Garner, Julie A. Griffith, Kallie Schafner, Madison Seaman, Kevin J. Engels, Kimberley Wix, Thomas P. Batchelor, William T. Goldsmith, Salik Hussain and Timothy R. Nurkiewicz Tags: Research Source Type: research
A novel insight into mechanism of derangement of coagulation balance: interactions of quantum dots with coagulation-related proteins
Quantum dots (QDs) have gained increased attention for their extensive biomedical and electronic products applications. Due to the high priority of QDs in contacting the circulatory system, understanding the h... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 8, 2022 Category: Toxicology Authors: Lingyan Zhang, Yingting Wu, Xingling Luo, Tianjiang Jia, Kexin Li, Lihong Zhou, Zhen Mao and Peili Huang Tags: Research Source Type: research
Controlled human exposure to diesel exhaust: a method for understanding health effects of traffic-related air pollution
Diesel exhaust (DE) is a major component of air pollution in urban centers. Controlled human exposure (CHE) experiments are commonly used to investigate the acute effects of DE inhalation specifically and also... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 25, 2022 Category: Toxicology Authors: Erin Long, Carley Schwartz and Christopher Carlsten Tags: Review Source Type: research
Malondialdehyde and anion patterns in exhaled breath condensate among subway workers
Underground transportation systems can contribute to the daily particulates and metal exposures for both commuter and subway workers. The redox and metabolic changes in workers exposed to such metal-rich parti... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 25, 2022 Category: Toxicology Authors: Jean-Jacques Sauvain, Maud Hemmendinger, Guillaume Su árez, Camille Creze, Nancy B. Hopf, Valérie Jouannique, Amélie Debatisse, Jacques A. Pralong, Pascal Wild and Irina Guseva Canu Tags: Research Source Type: research
The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells
People are exposed to ambient particulate matter (PM) from multiple sources simultaneously in both environmental and occupational settings. However, combinatory effects of particles from different sources have... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 21, 2022 Category: Toxicology Authors: Vegard S æter Grytting, Prem Chand, Marit Låg, Johan Øvrevik and Magne Refsnes Tags: Research Source Type: research
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway
Microplastics (MPs), which are smaller in size and difficult to degrade, can be easily ingested by marine life and enter mammals through the food chain. Our previous study demonstrated that following acute exp... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 17, 2022 Category: Toxicology Authors: Haibo Jin, Minghao Yan, Chun Pan, Zhenyu Liu, Xiaoxuan Sha, Chengyue Jiang, Luxi Li, Mengge Pan, Dongmei Li, Xiaodong Han and Jie Ding Tags: Research Source Type: research
Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice
The gut microbiota plays a vital role in host homeostasis and is associated with inflammation and cardiovascular disease (CVD) risk. Exposure to particulate matter (PM) is a known mediator of inflammation and ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 9, 2022 Category: Toxicology Authors: Danielle T. Phillippi, Sarah Daniel, Vaidehi Pusadkar, Victoria L. Youngblood, Kayla N. Nguyen, Rajeev K. Azad, Brian K. McFarlin and Amie K. Lund Tags: Research Source Type: research
Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions
Air pollution is an issue of increasing interest due to its globally relevant impacts on morbidity and mortality. Controlled human exposure (CHE) studies are often employed to investigate the impacts of pollut... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 9, 2022 Category: Toxicology Authors: Erin Long and Christopher Carlsten Tags: Review Source Type: research
Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution
Exposure to air pollution is associated with elevated cardiovascular risk. Evidence shows that omega-3 polyunsaturated fatty acids (omega-3 PUFA) may attenuate the adverse cardiovascular effects of exposure to... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 9, 2022 Category: Toxicology Authors: Hao Chen, Siqi Zhang, Wan Shen, Claudia Salazar, Alexandra Schneider, Lauren H. Wyatt, Ana G. Rappold, David Diaz-Sanchez, Robert B. Devlin, James M. Samet and Haiyan Tong Tags: Research Source Type: research
Lung function and self-rated symptoms in healthy volunteers after exposure to hydrotreated vegetable oil (HVO) exhaust with and without particles
Diesel engine exhaust causes adverse health effects. Meanwhile, the impact of renewable diesel exhaust, such as hydrotreated vegetable oil (HVO), on human health is less known. Nineteen healthy volunteers were... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 24, 2022 Category: Toxicology Authors: Louise Gren, Katrin Dierschke, Fredrik Mattsson, Eva Assarsson, Annette M. Krais, Monica K åredal, Karin Lovén, Jakob Löndahl, Joakim Pagels, Bo Strandberg, Martin Tunér, Yiyi Xu, Per Wollmer, Maria Albin, Jörn Nielsen, Anders Gudmundsson & hellip; Tags: Research Source Type: research
