Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
Together with poor biodegradability and insufficient recycling, the massive production and use of plastics have led to widespread environmental contamination by nano- and microplastics. These particles accumul... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 12, 2020 Category: Toxicology Authors: Nell Hirt and Mathilde Body-Malapel Tags: Review Source Type: research
Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies
Fetal development is a crucial window of susceptibility in which exposure may lead to detrimental health outcomes at birth and later in life. The placenta serves as a gatekeeper between mother and fetus. Knowl... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 2, 2020 Category: Toxicology Authors: Eva Bongaerts, Tim S. Nawrot, Thessa Van Pee, Marcel Ameloot and Hannelore Bov é Tags: Review Source Type: research
Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy
Plastic is everywhere. It is used in food packaging, storage containers, electronics, furniture, clothing, and common single-use disposable items. Microplastic and nanoplastic particulates are formed from bulk... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 24, 2020 Category: Toxicology Authors: Sara B. Fournier, Jeanine N. D ’Errico, Derek S. Adler, Stamatina Kollontzi, Michael J. Goedken, Laura Fabris, Edward J. Yurkow and Phoebe A. Stapleton Tags: Research Source Type: research
Even lobar deposition of poorly soluble gold nanoparticles (AuNPs) is similar to that of soluble silver nanoparticles (AgNPs)
Information on particle deposition, retention, and clearance is important when evaluating the risk of inhaled nanomaterials to human health. The revised Organization Economic Cooperation and Development (OECD)... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 20, 2020 Category: Toxicology Authors: Hoi Pin Kim, Jin Kwon Kim, Mi Seong Jo, Jung Duck Park, Kangho Ahn, Mary Gulumian, G ünter Oberdörster and Il Je Yu Tags: Research Source Type: research
Nanomaterial-mediated autophagy: coexisting hazard and health benefits in biomedicine
Widespread biomedical applications of nanomaterials (NMs) bring about increased human exposure risk due to their unique physicochemical properties. Autophagy, which is of great importance for regulating the ph... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 16, 2020 Category: Toxicology Authors: Xiaoli Feng, Yaqing Zhang, Chao Zhang, Xuan Lai, Yanli Zhang, Junrong Wu, Chen Hu and Longquan Shao Tags: Review Source Type: research
Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat
Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80–90 nm in diameter) are straight-type MWCNTs, and similarly to asbestos,... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 15, 2020 Category: Toxicology Authors: Dina Mourad Saleh, William T. Alexander, Takamasa Numano, Omnia Hosny Mohamed Ahmed, Sivagami Gunasekaran, David B. Alexander, Mohamed Abdelgied, Ahmed M. El-Gazzar, Hiroshi Takase, Jiegou Xu, Aya Naiki-Ito, Satoru Takahashi, Akihiko Hirose, Makoto Ohnish Tags: Research Source Type: research
Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin
While exposure to diesel exhaust particles has been linked to aberrant immune responses in allergic diseases such as asthma, little attention has been paid to their effects on the airway epithelial barrier. In... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 15, 2020 Category: Toxicology Authors: Timothy Smyth, Janelle Veazey, Sophia Eliseeva, David Chalupa, Alison Elder and Steve N. Georas Tags: Research Source Type: research
Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model
Titanium dioxide (TiO2) is broadly used in common consumer goods, including as a food additive (E171 in Europe) for colouring and opacifying properties. The E171 additive contains TiO2 nanoparticles (NPs), part o... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 7, 2020 Category: Toxicology Authors: A. Guillard, E. Gaultier, C. Cartier, L. Devoille, J. Noireaux, L. Chevalier, M. Morin, F. Grandin, M. Z. Lacroix, C. Com éra, A. Cazanave, A. de Place, V. Gayrard, V. Bach, K. Chardon, N. Bekhti & hellip; Tags: Research Source Type: research
Controlled human exposures to wood smoke: a synthesis of the evidence
Exposure to particulate matter (PM) from wood combustion represents a global health risk, encompassing diverse exposure sources; indoor exposures due to cooking in developing countries, ambient PM exposures fr... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 2, 2020 Category: Toxicology Authors: Carley Schwartz, Anette Kocbach B ølling and Christopher Carlsten Tags: Review Source Type: research
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE −/− mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage
The biosafety concern of silica nanoparticles (SiNPs) is rapidly expanding alongside with its mass production and extensive applications. The cardiovascular effects of SiNPs exposure have been gradually confir... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - October 2, 2020 Category: Toxicology Authors: Ru Ma, Yi Qi, Xinying Zhao, Xueyan Li, Xuejing Sun, Piye Niu, Yanbo Li, Caixia Guo, Rui Chen and Zhiwei Sun Tags: Research Source Type: research
Occupational exposure to carbon black nanoparticles increases inflammatory vascular disease risk: an implication of an ex vivo biosensor assay
Among manufactured or engineered nanoparticles, carbon black (CB) has largest production worldwide and is also an occupational respiratory hazard commonly seen in rubber industry. Few studies have assessed the... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - September 29, 2020 Category: Toxicology Authors: Jinglong Tang, Wenting Cheng, Jinling Gao, Yanting Li, Ruyong Yao, Nathaniel Rothman, Qing Lan, Matthew J. Campen, Yuxin Zheng and Shuguang Leng Tags: Research Source Type: research
NanoPASS: an easy-to-use user interface for nanoparticle dosimetry with the 3DSDD model
Nanoparticles exhibit a specific diffusion and sedimentation behavior under cell culture conditions as used in nantoxicological in vitro testing. How a particular particle suspension behaves depends on the par... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - September 18, 2020 Category: Toxicology Authors: Falko Frenzel, Laura K önig-Mattern, Valerie Stock, Linn Voss, Maxi B. Paul, Holger Sieg, Albert Braeuning, Andreas Voigt and Linda Böhmert Tags: Short report Source Type: research
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation
With the development of zinc oxide nanoparticles (ZnO NPs) in the field of nanotechnology, their toxicological effects are attracting increasing attention, and the mechanisms for ZnO NPs neurotoxicity remain o... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - September 18, 2020 Category: Toxicology Authors: Zixuan Liu, Xuying Lv, Lei Xu, Xuting Liu, Xiangyu Zhu, Erqun Song and Yang Song Tags: Research Source Type: research
Quartz crystal microbalances (QCM) are suitable for real-time dosimetry in nanotoxicological studies using VITROCELL ®Cloud cell exposure systems
Accurate knowledge of cell −/tissue-delivered dose plays a pivotal role in inhalation toxicology studies, since it is the key parameter for hazard assessment and translation of in vitro to in vivo dose-response... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - September 16, 2020 Category: Toxicology Authors: Yaobo Ding, Patrick Weindl, Anke-Gabriele Lenz, Paula Mayer, Tobias Krebs and Otmar Schmid Tags: Methodology Source Type: research
Carbon nanomaterial-derived lung burden analysis using UV-Vis spectrophotometry and proteinase K digestion
The quantification of nanomaterials accumulated in various organs is crucial in studying their toxicity and toxicokinetics. However, some types of nanomaterials, including carbon nanomaterials (CNMs), are diff... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - September 11, 2020 Category: Toxicology Authors: Dong-Keun Lee, Soyeon Jeon, Jiyoung Jeong, Kyung Seuk Song and Wan-Seob Cho Tags: Research Source Type: research
