Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation
Some organic chemicals are known to cause allergic disorders such as bronchial asthma and hypersensitivity pneumonitis, and it has been considered that they do not cause irreversible pulmonary fibrosis. It has... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 21, 2022 Category: Toxicology Authors: Chinatsu Nishida, Taisuke Tomonaga, Hiroto Izumi, Ke-Yong Wang, Hidenori Higashi, Toru Ishidao, Jun-ichi Takeshita, Ryohei Ono, Kazuki Sumiya, Shota Fujii, Shinichi Mochizuki, Kazuo Sakurai, Kei Yamasaki, Kazuhiro Yatera and Yasuo Morimoto Tags: Research Source Type: research
Coal dust exposure triggers heterogeneity of transcriptional profiles in mouse pneumoconiosis and Vitamin D remedies
Coal dust particles (CDP), an inevitable by-product of coal mining for the environment, mainly causes coal workers ’ pneumoconiosis (CWP). Long-term exposure to coal dust leads to a complex alternation of biolo... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 20, 2022 Category: Toxicology Authors: Min Mu, Bing Li, Yuanjie Zou, Wenyang Wang, Hangbing Cao, Yajun Zhang, Qixian Sun, Haoming Chen, Deyong Ge, Huihui Tao, Dong Hu, Liang Yuan, Xinrong Tao and Jianhua Wang Tags: Research Source Type: research
Use of an in silico knowledge discovery approach to determine mechanistic studies of silver nanoparticles-induced toxicity from in vitro to in vivo
Silver nanoparticles (AgNPs) are considered a double-edged sword that demonstrates beneficial and harmful effects depending on their dimensions and surface coating types. However, mechanistic understanding of ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 14, 2022 Category: Toxicology Authors: Bin-Hsu Mao, Yi-Kai Luo, Bour-Jr Wang, Chun-Wan Chen, Fong-Yu Cheng, Yu-Hsuan Lee, Shian-Jang Yan and Ying-Jan Wang Tags: Research Source Type: research
Exposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review
Autoimmunity can result from the interplay between genetic background and effects of environmental and/or occupational exposure to hazardous materials. Several compounds, including silica dust, have been linke... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 7, 2022 Category: Toxicology Authors: Lisa M. F. Janssen, Manosij Ghosh, Frauke Lemaire, K. Michael Pollard and Peter H. M. Hoet Tags: Review Source Type: research
Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E null mice
Fine particulate matter (PM2.5) exposure accelerates atherosclerosis and contains known ovotoxic chemicals. However, effects of exposure to PM2.5 on the finite ovarian follicle pool have hardly been investigated,... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 7, 2022 Category: Toxicology Authors: Ulrike Luderer, Jinhwan Lim, Laura Ortiz, Johnny D. Nguyen, Joyce H. Shin, Barrett D. Allen, Lisa S. Liao, Kelli Malott, Veronique Perraud, Lisa M. Wingen, Rebecca J. Arechavala, Bishop Bliss, David A. Herman and Michael T. Kleinman Tags: Research Source Type: research
Skin damage induced by zinc oxide nanoparticles combined with UVB is mediated by activating cell pyroptosis via the NLRP3 inflammasome –autophagy–exosomal pathway
Zinc oxide nanoparticles (ZnONPs) are widely used nanomaterial in personal cosmetics, such as skin creams and sunscreens, due to their whitening properties and strong UV light absorption. However, the safety i... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 5, 2022 Category: Toxicology Authors: Yu-Ying Chen, Yu-Hsuan Lee, Bour-Jr Wang, Rong-Jane Chen and Ying-Jan Wang Tags: Research Source Type: research
Oral administration of TiO2 nanoparticles during early life impacts cardiac and neurobehavioral performance and metabolite profile in an age- and sex-related manner
Nanoparticles (NPs) are increasingly incorporated in everyday products. To investigate the effects of early life exposure to orally ingested TiO2 NP, male and female Sprague –Dawley rat pups received four consecut... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 5, 2022 Category: Toxicology Authors: Ninell P. Mortensen, Wimal Pathmasiri, Rodney W. Snyder, Maria Moreno Caffaro, Scott L. Watson, Purvi R. Patel, Lakshmi Beeravalli, Sharmista Prattipati, Shyam Aravamudhan, Susan J. Sumner and Timothy R. Fennell Tags: Research Source Type: research
Rounded atelectasis after exposure to refractory ceramic fibres (RCF)
Refractory Ceramic fibres (RCF) are man-made mineral fibres used in high performance thermal insulation applications. Analogous to asbestos fibres, RCF are respirable, show a pleural drift and can persist in h... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 29, 2021 Category: Toxicology Authors: Ulrike Brueckner, Anne S. Schulze, Dirk Walter, Marian Kampschulte and Joachim Schneider Tags: Research Source Type: research
Histopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model
Multi-walled carbon nanotubes and nanofibers (CNT/F) have been previously investigated for their potential toxicities; however, comparative studies of the broad material class are lacking, especially those wit... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 20, 2021 Category: Toxicology Authors: Kelly Fraser, Ann Hubbs, Naveena Yanamala, Robert R. Mercer, Todd A. Stueckle, Jake Jensen, Tracy Eye, Lori Battelli, Sidney Clingerman, Kara Fluharty, Tiana Dodd, Gary Casuccio, Kristin Bunker, Traci L. Lersch, Michael L. Kashon, Marlene Orandle & hellip Tags: Research Source Type: research
Chemistry, lung toxicity and mutagenicity of burn pit smoke-related particulate matter
Open burning of anthropogenic sources can release hazardous emissions and has been associated with increased prevalence of cardiopulmonary health outcomes. Exposure to smoke emitted from burn pits in military ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 16, 2021 Category: Toxicology Authors: Yong Ho Kim, Sarah H. Warren, Ingeborg Kooter, Wanda C. Williams, Ingrid J. George, Samuel A. Vance, Michael D. Hays, Mark A. Higuchi, Stephen H. Gavett, David M. DeMarini, Ilona Jaspers and M. Ian Gilmour Tags: Research Source Type: research
Competitive and/or cooperative interactions of graphene-family materials and benzo[a]pyrene with pulmonary surfactant: a computational and experimental study
Airborne nanoparticles can be inhaled and deposit in human alveoli, where pulmonary surfactant (PS) molecules lining at the alveolar air –water interface act as the first barrier against inhaled nanoparticles e... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 16, 2021 Category: Toxicology Authors: Tongtao Yue, Rujie Lv, Dongfang Xu, Yan Xu, Lu Liu, Yanhui Dai, Jian Zhao and Baoshan Xing Tags: Research Source Type: research
Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction
We examined transcript... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 15, 2021 Category: Toxicology Authors: Quincy A. Hathaway, Nairrita Majumder, William T. Goldsmith, Amina Kunovac, Mark V. Pinti, Jack R. Harkema, Vince Castranova, John M. Hollander and Salik Hussain Tags: Research Source Type: research
Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production
Particulate matter (PM) containing environmentally persistent free radicals (EPFRs) are formed during various combustion processes, including the thermal remediation of hazardous wastes. Exposure to PM adverse... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 14, 2021 Category: Toxicology Authors: Avinash Kumar, Vivek S. Patel, Jeffrey N. Harding, Dahui You and Stephania A. Cormier Tags: Research Source Type: research
Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics
Nanoparticles have been utilized in brain research and therapeutics, including imaging, diagnosis, and drug delivery, owing to their versatile properties compared to bulk materials. However, exposure to nanopa... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 25, 2021 Category: Toxicology Authors: Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee, Shaherin Basith, Chan Seo, Man Jeong Paik, Sang-Wook Kim, Haewoon Seo, Ju Yeon Lee, Jin Young Kim, A Young Kim, Jee Min Chung, Eun Joo Baik, Seong Ho Kang, Dong-Kug Choi, Yup Kang & hellip; Tags: Research Source Type: research
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers
Engineered stone silicosis is an emerging disease in many countries worldwide produced by the inhalation of respirable dust of engineered stone. This silicosis has a high incidence among young workers, with a ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 22, 2021 Category: Toxicology Authors: Antonio Le ón-Jiménez, José M. Mánuel, Marcial García-Rojo, Marina G. Pintado-Herrera, José Antonio López-López, Antonio Hidalgo-Molina, Rafael García, Pedro Muriel-Cueto, Nieves Maira-González, Daniel Del Castillo-Otero and Francisco M. Morales Tags: Research Source Type: research
