Decidual derived exosomal miR-99a-5p targets Ppp2r5a to inhibit trophoblast invasion in response to CeO2NPs exposure
The biological effects of cerium dioxide nanoparticles (CeO2NPs), a novel material in the biomedical field, have attracted widespread attention. Our previous study confirmed that exposure to CeO2NPs during pregna... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 20, 2023 Category: Toxicology Authors: Hangtian Zhong, Yanqing Geng, Rufei Gao, Jun Chen, Zhuxiu Chen, Xinyi Mu, Yan Zhang, Xuemei Chen and Junlin He Tags: Research Source Type: research
Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation
Synthetic amorphous silica nanoparticles (SAS-NPs) are widely employed in pharmaceutics, cosmetics, food and concretes. Workers and the general population are exposed daily via diverse routes of exposure. SAS-... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 19, 2023 Category: Toxicology Authors: Éléonore Guillet, Émilie Brun, Céline Ferard, Kévin Hardonnière, Myriam Nabhan, François-Xavier Legrand, Marc Pallardy and Armelle Biola-Vidamment Tags: Research Source Type: research
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study
Pre-existing metabolic diseases may predispose individuals to particulate matter (PM)-induced adverse health effects. However, the differences in susceptibility of various metabolic diseases to PM-induced lung... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 17, 2023 Category: Toxicology Authors: Shen Chen, Miao Li, Rui Zhang, Lizhu Ye, Yue Jiang, Xinhang Jiang, Hui Peng, Ziwei Wang, Zhanyu Guo, Liping Chen, Rong Zhang, Yujie Niu, Michael Aschner, Daochuan Li and Wen Chen Tags: Research Source Type: research
Maternal exposure to ultrafine particles enhances influenza infection during pregnancy
Interactions between air pollution and infectious agents are increasingly recognized and critical to identify, especially to protect vulnerable populations. Pregnancy represents a vulnerable period for influen... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 17, 2023 Category: Toxicology Authors: Nicholas L. Drury, Toriq Mustapha, Ross A. Shore, Jiayun Zhao, Gus A. Wright, Aline Rodrigues Hoffmann, Susanne U. Talcott, Annette Regan, Robert M. Tighe, Renyi Zhang and Natalie M. Johnson Tags: Research Source Type: research
Biokinetics of subacutely co-inhaled same size gold and silver nanoparticles
Toxicokinetics of nanomaterials, including studies on the absorption, distribution, metabolism, and elimination of nanomaterials, are essential in assessing their potential health effects. The fate of nanomate... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 31, 2023 Category: Toxicology Authors: Philku Lee, Jin Kwon Kim, Mi Seong Jo, Hoi Pin Kim, Kangho Ahn, Jung Duck Park, Mary Gulumian, G ünter Oberdörster and Il Je Yu Tags: Research Source Type: research
ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo
Montmorillonite (Mt) and its derivatives are now widely used in industrial and biomedical fields. Therefore, safety assessments of these materials are critical to protect human health after exposure; however, ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 10, 2023 Category: Toxicology Authors: Jia Liu, Shubin Yang, Laien Zhao, Feng Jiang, Jianchao Sun, Shengjun Peng, Ruikang Zhao, Yanmei Huang, Xiaoxuan Fu, Rongrui Luo, Yu Jiang, Zelin Li, Nan Wang, Tengzheng Fang and Zhuhong Zhang Tags: Research Source Type: research
Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice
Air pollution has emerged as an unexpected risk factor for diabetes. However, the mechanism behind remains ill-defined. So far, the lung has been considered as the main target organ of air pollution. In contra... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 9, 2023 Category: Toxicology Authors: Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Lena Keller, Zora Baumann, Neena Parayil, Marc Stawiski, Leila Rachid, Thomas Dervos, Sandra Mitrovic, Daniel T. Meier and Claudia Cavelti-Weder Tags: Research Source Type: research
Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammation
A recent epidemiological study showed that air pollution is closely involved in the prognosis of ischemic stroke. We and others have reported that microglial activation in ischemic stroke plays an important ro... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 16, 2023 Category: Toxicology Authors: Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F. A. Vogel and Yasuhiro Ishihara Tags: Research Source Type: research
Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis
Toxicity assessment for regulatory purposes is starting to move away from traditional in vivo methods and towards new approach methodologies (NAM) such as high-throughput in vitro models and computational tool... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 9, 2023 Category: Toxicology Authors: Polly McLean, William Mueller, Ilse Gosens, Flemming R. Cassee, Barbara Rothen-Rutishauser, Matthew Boyles and Lang Tran Tags: Research Source Type: research
Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice
Acute phase response (APR) is characterized by a change in concentration of different proteins, including C-reactive protein and serum amyloid A (SAA) that can be linked to both exposure to metal oxide nanomat... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 17, 2023 Category: Toxicology Authors: Claudia Torero Gutierrez, Charis Loizides, Iosif Hafez, Anders Brostr øm, Henrik Wolff, Józef Szarek, Trine Berthing, Alicja Mortensen, Keld Alstrup Jensen, Martin Roursgaard, Anne Thoustrup Saber, Peter Møller, George Biskos and Ulla Vogel Tags: Research Source Type: research
Short- and long-term polystyrene nano- and microplastic exposure promotes oxidative stress and divergently affects skin cell architecture and Wnt/beta-catenin signaling
Nano- and microplastic particles (NMP) are strong environmental contaminants affecting marine ecosystems and human health. The negligible use of biodegradable plastics and the lack of knowledge about plastic u... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 16, 2023 Category: Toxicology Authors: Anke Schmidt, Walison Augusto da Silva Brito, Debora Singer, Melissa M ühl, Julia Berner, Fariba Saadati, Christina Wolff, Lea Miebach, Kristian Wende and Sander Bekeschus Tags: Research Source Type: research
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF- κB pathway due to mitochondrial damage
Polypropylene (PP) is used in various products such as disposable containers, spoons, and automobile parts. The disposable masks used for COVID-19 prevention mainly comprise PP, and the disposal of such masks ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 10, 2023 Category: Toxicology Authors: Jong-Hwan Woo, Hyeon Jin Seo, Jun-Young Lee, Iljung Lee, Kisoo Jeon, Bumseok Kim and Kyuhong Lee Tags: Research Source Type: research
Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review
Adverse outcome pathways (AOPs) are conceptual frameworks that organize knowledge about biological interactions and toxicity mechanisms. They present a sequence of events commencing with initial interaction(s)... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 5, 2023 Category: Toxicology Authors: Ozge Kose, Paride Mantecca, Anna Costa and Marie Carri ère Tags: Research Source Type: research
Correction: a systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective
(Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 28, 2022 Category: Toxicology Authors: Kirsi M. Siivola, Michael J. Burgum, Blanca Su árez-Merino, Martin J. D. Clift, Shareen H. Doak and Julia Catalán Tags: Correction Source Type: research
Pulmonary effects of exposure to indium and its compounds: cross-sectional survey of exposed workers and experimental findings in rodents
Many studies have shown that occupational exposure to indium and its compounds could induce lung disease. Although animal toxicological studies and human epidemiological studies suggest indium exposure may cau... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 20, 2022 Category: Toxicology Authors: Nan Liu, Yi Guan, Yan Yu, Gai Li, Ling Xue, Weikang Li, Xiaoyu Qu, Ning Li and Sanqiao Yao Tags: Research Source Type: research
