Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis
Particulate matter (PM) is strongly linked to human health and has detrimental effects on the eye. Studies have, however, focused on the ocular surface, with limited research on the impact of PM2.5 on intraocular... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 4, 2021 Category: Toxicology Authors: Liping Li, Chao Xing, Ji Zhou, Liangliang Niu, Bin Luo, Maomao Song, Jingping Niu, Ye Ruan, Xinghuai Sun and Yuan Lei Tags: Research Source Type: research
Femtosecond pulsed laser microscopy: a new tool to assess the in vitro delivered dose of carbon nanotubes in cell culture experiments
In vitro models are widely used in nanotoxicology. In these assays, a careful documentation of the fraction of nanomaterials that reaches the cells, i.e. the in vitro delivered dose, is a critical element for ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 18, 2021 Category: Toxicology Authors: Dominique Lison, Saloua Ibouraadaten, Sybille van den Brule, Milica Todea, Adriana Vulpoi, Flaviu Turcu, Christina Ziemann, Otto Creutzenberg, James C. Bonner, Marcel Ameloot and Hannelore Bov é Tags: Methodology Source Type: research
The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs
Up to 44% of particulates of food-grade titanium dioxide (TiO2) are in nanoscale, while the effect and combined effect of which with other substances on intestinal barrier haven ’t been fully understood yet. This ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 17, 2021 Category: Toxicology Authors: Yongliang Zhang, Shumin Duan, Ying Liu and Yun Wang Tags: Research Source Type: research
Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice
Ambient air pollution by particulate matters, including diesel exhaust particles (DEP), is a major cause of cardiovascular and metabolic mortality worldwide. The mechanisms by which DEP cause these adverse out... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 9, 2021 Category: Toxicology Authors: Sybille van den Brule, Margaux Rappe, J érôme Ambroise, Caroline Bouzin, Chantal Dessy, Adrien Paquot, Giulio G. Muccioli and Dominique Lison Tags: Research Source Type: research
Macrophage autophagy protects mice from cerium oxide nanoparticle-induced lung fibrosis
Cerium (Ce) is a rare earth element, rapidly oxidizing to form CeO2, and currently used in numerous commercial applications, especially as nanoparticles (NP). The potential health effects of Ce remain uncertain, ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 1, 2021 Category: Toxicology Authors: Balasubramanyam Annangi, Zhuyi Lu, Jonathan Bruniaux, Audrey Ridoux, Vanessa Marques da Silva, Delphine Vantelon, Jorge Boczkowski and Sophie Lanone Tags: Research Source Type: research
Lung retention and particokinetics of silver and gold nanoparticles in rats following subacute inhalation co-exposure
Inhalation exposure to nanomaterials in workplaces can include a mixture of multiple nanoparticles. Such ambient nanoparticles can be of high dissolution or low dissolution in vivo and we wished to determine w... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 21, 2021 Category: Toxicology Authors: Jin Kwon Kim, Hoi Pin Kim, Jung Duck Park, Kangho Ahn, Woo Young Kim, Mary Gulumian, G ünter Oberdörster and Il Je Yu Tags: Research Source Type: research
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Depending on their distinct properties, titanium dioxide nanoparticles (TiO2-NPs) are manufactured extensively and widely present in our daily necessities, with growing environmental release and public concerns. ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 9, 2021 Category: Toxicology Authors: Yen-Ju Chan, Po-Lin Liao, Chi-Hao Tsai, Yu-Wen Cheng, Fan-Li Lin, Jau-Der Ho, Ching-Yi Chen and Ching-Hao Li Tags: Research Source Type: research
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet
Exposure to traffic-generated emissions is associated with the development and exacerbation of inflammatory lung disorders such as chronic obstructive pulmonary disorder (COPD) and idiopathic pulmonary fibrosi... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 8, 2021 Category: Toxicology Authors: Sarah Daniel, Danielle Phillippi, Leah J. Schneider, Kayla N. Nguyen, Julie Mirpuri and Amie K. Lund Tags: Research Source Type: research
Cardiovascular health impacts of wildfire smoke exposure
In recent years, wildland fires have occurred more frequently and with increased intensity in many fire-prone areas. In addition to the direct life and economic losses attributable to wildfires, the emitted sm... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 7, 2021 Category: Toxicology Authors: Hao Chen, James M. Samet, Philip A. Bromberg and Haiyan Tong Tags: Review Source Type: research
Cobalt oxide nanoparticles induce oxidative stress and alter electromechanical function in rat ventricular myocytes
Nanotoxicology is an increasingly relevant field and sound paradigms on how inhaled nanoparticles (NPs) interact with organs at the cellular level, causing harmful conditions, have yet to be established. This ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - January 6, 2021 Category: Toxicology Authors: Monia Savi, Leonardo Bocchi, Francesca Cacciani, Rocchina Vilella, Annamaria Buschini, Alessio Perotti, Serena Galati, Serena Montalbano, Silvana Pinelli, Caterina Frati, Emilia Corradini, Federico Quaini, Roberta Ruotolo, Donatella Stilli and Massimilian Tags: Research Source Type: research
Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities
Carbon nanotubes and nanofibers (CNT/F) have known toxicity but simultaneous comparative studies of the broad material class, especially those with a larger diameter, with computational analyses linking toxici... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 7, 2020 Category: Toxicology Authors: Kelly Fraser, Vamsi Kodali, Naveena Yanamala, M. Eileen Birch, Lorenzo Cena, Gary Casuccio, Kristin Bunker, Traci L. Lersch, Douglas E. Evans, Aleksandr Stefaniak, Mary Ann Hammer, Michael L. Kashon, Theresa Boots, Tracy Eye, John Hubczak, Sherri A. Frien Tags: Research Source Type: research
The critical role of endothelial function in fine particulate matter-induced atherosclerosis
Ambient and indoor air pollution contributes annually to approximately seven million premature deaths. Air pollution is a complex mixture of gaseous and particulate materials. In particular, fine particulate m... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - December 4, 2020 Category: Toxicology Authors: Shuang Liang, Jingyi Zhang, Ruihong Ning, Zhou Du, Jiangyan Liu, Joe Werelagi Batibawa, Junchao Duan and Zhiwei Sun Tags: Review Source Type: research
Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats
The objective of this study was to investigate the effects o... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 26, 2020 Category: Toxicology Authors: Hsiao-Chi Chuang, Hsin-Chang Chen, Pei-Jui Chai, Ho-Tang Liao, Chang-Fu Wu, Chia-Ling Chen, Ming-Kai Jhan, Hui-I Hsieh, Kuen-Yuh Wu, Ta-Fu Chen and Tsun-Jen Cheng Tags: Research Source Type: research
The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method
Inhalation of multi-walled carbon nanotubes (MWCNTs) poses a potential risk to human health. In order to safeguard workers and consumers, the toxic properties of MWCNTs need to be identified. Functionalization... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 26, 2020 Category: Toxicology Authors: Alexia J. Taylor-Just, Mark D. Ihrie, Katherine S. Duke, Ho Young Lee, Dorothy J. You, Salik Hussain, Vamsi K. Kodali, Christina Ziemann, Otto Creutzenberg, Adriana Vulpoi, Flaviu Turcu, Monica Potara, Milica Todea, Sybille van den Brule, Dominique Lison Tags: Research Source Type: research
Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults
Fine particulate matter (PM2.5) related mild inflammation, altered autonomic control of cardiovascular function, and changes to cell function have been observed in controlled human exposure studies. (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - November 16, 2020 Category: Toxicology Authors: Lauren H. Wyatt, Robert B. Devlin, Ana G. Rappold, Martin W. Case and David Diaz-Sanchez Tags: Research Source Type: research
