In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT
Multi-walled carbon nanotubes (MWCNT) have received attention due to extraordinary properties, resulting in concerns for occupational health and safety. Costs and ethical concerns of animal testing drive a nee... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - July 23, 2021 Category: Toxicology Authors: Emilio Di Ianni, Johanna Samulin Erdem, Peter M øller, Nicklas Mønster Sahlgren, Sarah Søs Poulsen, Kristina Bram Knudsen, Shan Zienolddiny, Anne Thoustrup Saber, Håkan Wallin, Ulla Vogel and Nicklas Raun Jacobsen Tags: Research Source Type: research
Prolonged exposure to traffic-related particulate matter and gaseous pollutants implicate distinct molecular mechanisms of lung injury in rats
In this study, we investigated the effect... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - June 25, 2021 Category: Toxicology Authors: Yu-Teng Jheng, Denise Utami Putri, Hsiao-Chi Chuang, Kang-Yun Lee, Hsiu-Chu Chou, San-Yuan Wang and Chia-Li Han Tags: Research Source Type: research
Size and surface modification of silica nanoparticles affect the severity of lung toxicity by modulating endosomal ROS generation in macrophages
As the application of silica nanomaterials continues to expand, increasing chances of its exposure to the human body and potential harm are anticipated. Although the toxicity of silica nanomaterials is assumed... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - June 17, 2021 Category: Toxicology Authors: Masahide Inoue, Koji Sakamoto, Atsushi Suzuki, Shinya Nakai, Akira Ando, Yukihiko Shiraki, Yoshio Nakahara, Mika Omura, Atsushi Enomoto, Ikuhiko Nakase, Makoto Sawada and Naozumi Hashimoto Tags: Research Source Type: research
Repeated oral administration of low doses of silver in mice: tissue distribution and effects on central nervous system
Widespread use of silver in its different forms raises concerns about potential adverse effects after ingestion, the main exposure route for humans. The aim of this study was to investigate in CD-1 (ICR) male ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - June 16, 2021 Category: Toxicology Authors: Camilla Recordati, Marcella De Maglie, Claudia Cella, Simona Argentiere, Saverio Paltrinieri, Silvia Bianchessi, Marco Losa, Fabio Fiordaliso, Alessandro Corbelli, Gianpaolo Milite, Federica Aureli, Marilena D ’Amato, Andrea Raggi, Francesco Cubadda, Sa Tags: Research Source Type: research
Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: a crossover study
Air pollution derived from combustion is associated with considerable cardiorespiratory morbidity and mortality in addition to environmental effects. Replacing petrodiesel with biodiesel may have ecological be... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - June 14, 2021 Category: Toxicology Authors: Jon Unosson, Mikael Kab éle, Christoffer Boman, Robin Nyström, Ioannis Sadiktsis, Roger Westerholm, Ian S. Mudway, Esme Purdie, Jennifer Raftis, Mark R. Miller, Nicholas L. Mills, David E. Newby, Anders Blomberg, Thomas Sandström and Jenny A. Bosson Tags: Research Source Type: research
Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis
Micro- and nanoplastic pollution has become a global environmental problem. Nanoplastics in the environment are still hard to detect because of analysis technology limitations. It is believed that when micropl... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - June 7, 2021 Category: Toxicology Authors: Boxuan Liang, Yizhou Zhong, Yuji Huang, Xi Lin, Jun Liu, Li Lin, Manjiang Hu, Junying Jiang, Mingzhu Dai, Bo Wang, Bingli Zhang, Hao Meng, Jesse Justin J. Lelaka, Haixia Sui, Xingfen Yang and Zhenlie Huang Tags: Research Source Type: research
Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation
Although airborne fine particulate matter (PM) pollution has been demonstrated as an independent risk factor for pulmonary and cardiovascular diseases, their currently-available toxicological data is still far... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - May 13, 2021 Category: Toxicology Authors: Xiaoting Jin, Hongyan Yu, Baoqiang Wang, Zhendong Sun, Ze Zhang, Qian S. Liu, Yuxin Zheng, Qunfang Zhou and Guibin Jiang Tags: Research Source Type: research
Respirable stone particles differ in their ability to induce cytotoxicity and pro-inflammatory responses in cell models of the human airways
Respirable stone- and mineral particles may be a major constituent in occupational and ambient air pollution and represent a possible health hazard. However, with exception of quartz and asbestos, little is kn... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - May 6, 2021 Category: Toxicology Authors: Vegard S æter Grytting, Magne Refsnes, Johan Øvrevik, Marit Sigrid Halle, Jasmin Schönenberger, Roelant van der Lelij, Brynhild Snilsberg, Tonje Skuland, Richard Blom and Marit Låg Tags: Research Source Type: research
Biotransformation of rare earth oxide nanoparticles eliciting microbiota imbalance
Disruption of microbiota balance may result in severe diseases in animals and phytotoxicity in plants. While substantial concerns have been raised on engineered nanomaterial (ENM) induced hazard effects (e.g., lu... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 26, 2021 Category: Toxicology Authors: Huizhen Zheng, Zonglin Gu, Yanxia Pan, Jie Chen, Qianqian Xie, Shujuan Xu, Meng Gao, Xiaoming Cai, Shengtang Liu, Weili Wang, Wei Li, Xi Liu, Zaixing Yang, Ruhong Zhou and Ruibin Li Tags: Research Source Type: research
Respiratory and systemic impacts following MWCNT inhalation in B6C3F1/N mice
A very pure multi-walled carbon nanotube (MWCNT) that was shown to have very low toxicity in vitro, was evaluated for lung and systemic effects and distribution following inhalation exposure. (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 26, 2021 Category: Toxicology Authors: Christopher T. Migliaccio, Raymond F. Hamilton Jr, Pamela K. Shaw, Joseph F. Rhoderick, Sanghamitra Deb, Rohit Bhargava, Jack R. Harkema and Andrij Holian Tags: Research Source Type: research
Chronic exposure to PM2.5 aggravates SLE manifestations in lupus-prone mice
Air pollution causes negative impacts on health. Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical manifestations and multifactorial etiology. Recent studies suggest that air po... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 25, 2021 Category: Toxicology Authors: Victor Yuji Yariwake, Jana ína Iannicelli Torres, Amandda Rakell Peixoto dos Santos, Sarah Cristina Ferreira Freitas, Kátia De Angelis, Sylvia Costa Lima Farhat, Niels Olsen Saraiva Câmara and Mariana Matera Veras Tags: Research Source Type: research
Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen narrowing: a quantitative computerized tomography study in Chinese diesel engine testers
Diesel exhaust (DE) is a major source of ultrafine particulate matters (PM) in ambient air and contaminates many occupational settings. Airway remodeling assessed using computerized tomography (CT) correlates ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 25, 2021 Category: Toxicology Authors: Hong Liu, Jianyu Li, Qianli Ma, Jinglong Tang, Menghui Jiang, Xue Cao, Li Lin, Nan Kong, Shanfa Yu, Akshay Sood, Yuxin Zheng, Shuguang Leng and Wei Han Tags: Research Source Type: research
Effects of metal nanoparticles on tight junction-associated proteins via HIF-1 α/miR-29b/MMPs pathway in human epidermal keratinocytes
The increasing use of metal nanoparticles in industry and biomedicine raises the risk for unintentional exposure. The ability of metal nanoparticles to penetrate the skin ranges from stopping at the stratum co... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 19, 2021 Category: Toxicology Authors: Jiali Yuan, Yue Zhang, Yuanbao Zhang, Yiqun Mo and Qunwei Zhang Tags: Research Source Type: research
Differential effects of intense exercise and pollution on the airways in a murine model
Exercise-induced bronchoconstriction (EIB) is a transient airway narrowing, occurring during or shortly after intensive exercise. It is highly prevalent in non-asthmatic outdoor endurance athletes suggesting a... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 15, 2021 Category: Toxicology Authors: Tatjana Decaesteker, Eliane Vanhoffelen, Kristel Trekels, Anne-Charlotte Jonckheere, Jonathan Cremer, Arno Vanstapel, Ellen Dilissen, Dominique Bullens, Lieven J. Dupont and Jeroen A. Vanoirbeek Tags: Research Source Type: research
Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19
Air pollution exposure and idiopathic pulmonary fibrosis (IPF) cause a poor prognosis after SARS-CoV-2 infection, but the underlying mechanisms are not well explored. Angiotensin-converting enzyme 2 (ACE2) and... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 11, 2021 Category: Toxicology Authors: Hsin-Hsien Li, Chen-Chi Liu, Tien-Wei Hsu, Jiun-Han Lin, Jyuan-Wei Hsu, Anna Fen-Yau Li, Yi-Chen Yeh, Shih-Chieh Hung and Han-Shui Hsu Tags: Research Source Type: research
