The Clinical Utility of 18F-Fluciclovine PET/CT in Biochemically Recurrent Prostate Cancer: an Academic Center Experience Post FDA Approval
Conclusion18F-Fluciclovine PET/CT remains a useful diagnostic tool in the workup of patients with BCR PC, changing clinical management in 62 % of participants in our cohort. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
Evaluation of Optimal Post-Injection Timing of Hypoxic Imaging with 18F-Fluoromisonidazole-PET/CT
ConclusionsWe observed a high correlation between the quantitative values at 2 h and 4 h. When using a combined high-quality PET/CT, the total examination time for FMISO-PET can be shortened by skipping the 4-h scan. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
Selective Imaging of Matrix Metalloproteinase-13 to Detect Extracellular Matrix Remodeling in Atherosclerotic Lesions
ConclusionsWhile both radiotracers successfully identified atherosclerotic plaques, [18F]FMBP showed superior specificity and sensitivity for lesions possessing features of destructive plaque remodeling. The detection of ECM remodeling by selective targeting of MMP-13 may enable characterization of high-risk atherosclerosis featuring elevated collagenase activity. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 6, 2021 Category: Molecular Biology Source Type: research
Biodistribution of 18F-AlF-NOTA-octreotide in Different Organs and Characterization of Uptake in Neuroendocrine Neoplasms
ConclusionsThe results obtained from the majority of the samples in this study show the biodistribution of18F-OC in normal organs and have significance as a reference. Although some benign lesions show variable uptake, the uptake by these lesions is still different from that of NENs. NENs of different grades have differences in18F-OC uptake levels. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 6, 2021 Category: Molecular Biology Source Type: research
Mixing Matrix-corrected Whole-body Pharmacokinetic Modeling Using Longitudinal Micro-computed Tomography and Fluorescence-mediated Tomography
ConclusionsThe mixing matrix correction improves pharmacokinetic modeling and thus enables a more accurate assessment of the biodistribution of fluorescently labeled pharmaceuticals by μCT-FMT. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 6, 2021 Category: Molecular Biology Source Type: research
