Correction to: Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB ® Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models
(Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - August 16, 2021 Category: Molecular Biology Source Type: research
GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[18F]F-FDG-PET
ConclusionsMetabolic changes during doxorubicin treatment can be predicted by glucoCEST imaging that appears more sensitive than [18F]F-FDG-PET in reporting on therapeutic response. These findings support the view that glucoCEST may be a sensitive technique for monitoring metabolic response, but future studies are needed to explore the accuracy of this approach in other tumor types and treatments. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - August 12, 2021 Category: Molecular Biology Source Type: research
Translational Development of a Zr-89-Labeled Inhibitor of Prostate-specific Membrane Antigen for PET Imaging in Prostate Cancer
Conclusion[89Zr]Zr-PSMA-DFO is a promising PSMA PET tracer for detection of tumor areas with lower PSMA expression and thus warrants further clinical evaluation. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - August 9, 2021 Category: Molecular Biology Source Type: research
Correction to: High-Yielding Radiosynthesis of [68 Ga]Ga-PSMA-11 Using a Low-Cost Microfluidic Device
(Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - August 2, 2021 Category: Molecular Biology Source Type: research
Letter to the Editor: “Integration of PET/CT Radiomics and Semantic Features for Differentiation Between Active Pulmonary Tuberculosis and Lung Cancer”
(Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 28, 2021 Category: Molecular Biology Source Type: research
Molecular Imaging Reveals a High Degree of Cross-Seeding of Spontaneous Metastases in a Novel Mouse Model of Synchronous Bilateral Breast Cancer
ConclusionsA high degree of metastatic cross-seeding of cancer cells derived from bilateral tumors may contribute to faster metastatic growth and intratumoral heterogeneity. We posit that our work will help understand treatment resistance and optimal planning of SBBC treatment. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 26, 2021 Category: Molecular Biology Source Type: research
Reply to Letter to Editor RE: “Integration of PET/CT Radiomics and Semantic Features for Differentiation Between Active Pulmonary Tuberculosis and Lung Cancer”
(Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 26, 2021 Category: Molecular Biology Source Type: research
Correction to: Cross-Modality Imaging of Murine Tumor Vasculature —a Feasibility Study
(Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 23, 2021 Category: Molecular Biology Source Type: research
Examining the Feasibility of Quantifying Receptor Availability Using Cross-Modality Paired-Agent Imaging
ConclusionThese results suggest that cross-modality paired-agent imaging for quantifying receptor availability is feasible. Ultimately, cross-modality paired-agent imaging could facilitate rapid, noninvasive receptor availability quantification in humans using hybrid clinical imaging modalities. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 20, 2021 Category: Molecular Biology Source Type: research
Molecular Imaging, How Close to Clinical Precision Medicine in Lung, Brain, Prostate and Breast Cancers
AbstractPrecision medicine is playing a pivotal role in strategies of cancer therapy. Unlike conventional one-size-fits-all chemotherapy or radiotherapy modalities, precision medicine could customize an individual treatment plan for cancer patients to acquire superior efficacy, while minimizing side effects. Precision medicine in cancer therapy relies on precise and timely tumor biological information. Traditional tissue biopsies, however, are often inadequate in meeting this requirement due to cancer heterogeneity, poor tolerance, and invasiveness. Molecular imaging could detect tumor biology characterization in a noninva...
Source: Molecular Imaging and Biology - July 16, 2021 Category: Molecular Biology Source Type: research
Synthesis and Initial Characterization of a Reversible, Selective 18F-Labeled Radiotracer for Human Butyrylcholinesterase
ConclusionsThe reversibly acting, selective radiotracer is synthetically easily accessible and retains promising activity and binding potential onhBChE. Radiosynthesis with18F labeling of tosylates was feasible in a reasonable time frame and good radiochemical yield. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
Spectrum of [18F]FDG-PET/CT Findings in Benign Lymph Node Pathology
AbstractDiffuse lymphadenopathy has a long differential diagnosis that includes both malignant and benign causes. As part of the lymphadenopathy work-up, many patients undergo [18F]FDG-PET/CT for purposes of ruling out malignancy. FDG-avid lymph nodes, however, are not specific for malignancy. This review will illustrate the spectrum of nodal findings on FDG-PET/CT with correlation to other cross-sectional imaging and clinical history in patients with representative infectious, inflammatory, and benign lymphoproliferative disorders. These findings are important for the nuclear medicine radiologist to understand, as they ca...
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
Effect of Shortening the Scan Duration on Quantitative Accuracy of [18F]Flortaucipir Studies
ConclusionsThis study demonstrated that [18F]flortaucipir PET scan can be acquired with sufficient quantitative accuracy using only 50 min of dual-time-window scanning time. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
Synthesis and Characterization of [18F]JNJ-46356479 as the First 18F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2
Conclusions[18F]8 readily crosses the blood-brain barrier and demonstrates fast and reversible kinetics both in rodents and in a non-human primate. Further investigation of [18F]8 on its binding specificity would warrant translational study in human. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
The Clinical Utility of 18F-Fluciclovine PET/CT in Biochemically Recurrent Prostate Cancer: an Academic Center Experience Post FDA Approval
Conclusion18F-Fluciclovine PET/CT remains a useful diagnostic tool in the workup of patients with BCR PC, changing clinical management in 62 % of participants in our cohort. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - July 14, 2021 Category: Molecular Biology Source Type: research
