Traumatic brain injury and sight loss in military and veteran populations – a review
AbstractWar and combat exposure pose great risks to the vision system. More recently, vision related deficiencies and impairments have become common with the increased use of powerful explosive devices and the subsequent rise in incidence of traumatic brain injury (TBI). Studies have looked at the effects of injury severity, aetiology of injury and the stage at which visual problems become apparent. There was little discrepancy found between the frequencies or types of visual dysfunctions across blast and non-blast related groups, however complete sight loss appeared to occur only in those who had a blast-related injury. G...
Source: Military Medical Research - July 28, 2021 Category: International Medicine & Public Health Source Type: research
Is oxygen therapy beneficial for normoxemic patients with acute heart failure? A propensity score matched study
ConclusionRoutine use of supplemental oxygen in AHF patients without hypoxemia was not found to reduce all-cause in-hospital mortality or ICU mortality. (Source: Military Medical Research)
Source: Military Medical Research - July 9, 2021 Category: International Medicine & Public Health Source Type: research
Association of fluid balance trajectories with clinical outcomes in patients with septic shock: a prospective multicenter cohort study
ConclusionLatent subgroups of septic patients followed a similar FB progression. These latent fluid trajectories were associated with clinical outcomes. The decreasing FB trajectory was associated with a decreased risk of hospital mortality and MAKE. (Source: Military Medical Research)
Source: Military Medical Research - July 6, 2021 Category: International Medicine & Public Health Source Type: research
Meta-analysis with zero-event studies: a comparative study with application to COVID-19 data
ConclusionsWe recommend the new method to handle the zero-event studies when there are few studies in a meta-analysis, or instead use the GLMM when the number of studies is large. The double-zero-event studies may be informative, and so we suggest not excluding them. (Source: Military Medical Research)
Source: Military Medical Research - July 3, 2021 Category: International Medicine & Public Health Source Type: research
Clinical features, radiological profiles, pathological features and surgical outcomes of pituicytomas: a report of 11 cases and a pooled analysis of individual patient data
ConclusionsPituicytomas are more common in middle-aged people and the sellar region. The clinical manifestations of pituicytomas are different, but no diagnostic clinical features have been identified other than an abnormally abundant blood supply. Currently, GTR is the best approach for the treatment of pituicytomas. More patients and longer follow-up periods were needed to further elucidate the biological features of pituicytomas. (Source: Military Medical Research)
Source: Military Medical Research - July 2, 2021 Category: International Medicine & Public Health Source Type: research
RIG-I, a novel DAMPs sensor for myoglobin, activates NF- κB/caspase-3 signaling in CS-AKI model
ConclusionRIG-I is a novel damage-associated molecular patterns (DAMPs) sensor for myoglobin and participates in the NF- κB/caspase-3 signaling pathway in CS-AKI. In the development of CS-AKI, specific intervention in the RIG-I pathway might be a potential therapeutic strategy for CS-AKI. (Source: Military Medical Research)
Source: Military Medical Research - June 21, 2021 Category: International Medicine & Public Health Source Type: research
RIG-I, a novel DAMPs sensor for myoglobin activates NF- κB/caspase-3 signaling in CS-AKI model
ConclusionRIG-I is a novel damage-associated molecular patterns (DAMPs) sensor for myoglobin and participates in the NF- κB/caspase-3 signaling pathway in CS-AKI. In the development of CS-AKI, specific intervention in the RIG-I pathway might be a potential therapeutic strategy for CS-AKI. (Source: Military Medical Research)
Source: Military Medical Research - June 21, 2021 Category: International Medicine & Public Health Source Type: research
Bioelectrical impedance analysis-guided fluid management promotes primary fascial closure after open abdomen: a randomized controlled trial
ConclusionAmong postinjury OA patients in the ICU, the use of BIA-guided fluid resuscitation resulted in a higher PFC rate and fewer severe complications than the traditional fluid resuscitation strategy. (Source: Military Medical Research)
Source: Military Medical Research - June 7, 2021 Category: International Medicine & Public Health Source Type: research
Hydration status, body composition, and anxiety status in aeronautical military personnel from Spain: a cross-sectional study
ConclusionsThese findings all suggest a relationship between hydration status and body composition but also set the bases for future studies that relate hydration status and anxiety status. These results can be used to improve the hydration status and body composition of military personnel. (Source: Military Medical Research)
Source: Military Medical Research - June 2, 2021 Category: International Medicine & Public Health Source Type: research
Comparative study on the antituberculous effect and mechanism of the traditional Chinese medicines NiuBeiXiaoHe extract and JieHeWan
ConclusionsNBXH had therapeutic effects similar to those of JHW in improving lung histopathology, reducing lung colony counts, and regulating the levels of cytokines. NBXH restored significant changes in gene expression and repaired cell damage caused byM. tuberculosis infection by regulating immune-related pathways, which clarified the mechanism of action of NBXH. (Source: Military Medical Research)
Source: Military Medical Research - June 2, 2021 Category: International Medicine & Public Health Source Type: research
Intelligent prediction of RBC demand in trauma patients using decision tree methods
ConclusionsThe classification performance of the intelligent prediction model of red blood cell transfusion in trauma patients constructed by the decision tree algorithm is not inferior to that of the traditional LR method. It can be used as a technical support to assist doctors to make rapid and accurate blood transfusion decisions in emergency rescue environment, so as to improve the success rate of patient treatment. (Source: Military Medical Research)
Source: Military Medical Research - May 24, 2021 Category: International Medicine & Public Health Source Type: research
Preferences for pre-exposure prophylaxis among U.S. military men who have sex with men: results of an adaptive choice based conjoint analysis study
ConclusionA PrEP program consisting of daily tablet is preferred in military healthcare settings is preferred. Long-acting implants and injections are also desired. (Source: Military Medical Research)
Source: Military Medical Research - May 19, 2021 Category: International Medicine & Public Health Source Type: research
Predictive modelling for COVID-19 outbreak control: lessons from the navy cluster in Sri Lanka
AbstractIn response to an outbreak of coronavirus disease 2019 (COVID-19) within a cluster of Navy personnel in Sri Lanka commencing from 22nd April 2020, an aggressive outbreak management program was launched by the Epidemiology Unit of the Ministry of Health. To predict the possible number of cases within the susceptible population under four social distancing scenarios, the COVID-19 Hospital Impact Model for Epidemics (CHIME) was used. With increasing social distancing, the epidemiological curve flattened, and its peak shifted to the right. The observed or actually reported number of cases was above the projected number...
Source: Military Medical Research - May 18, 2021 Category: International Medicine & Public Health Source Type: research
Simulated aeromedical evacuation exacerbates burn induced lung injury: targeting mitochondrial DNA for reversal
ConclusionsOur results suggested that simulated aeromedical evacuation further increased burn-induced mtDNA release and exacerbated burn-induced inflammation and lung injury. DNase I reduced the release of mtDNA, limited mtDNA-induced systemic inflammation, and ameliorated burn-induced ALI. The intervening mtDNA level is thus a potential target to protect from burn-induced lung injury during aeromedical conditions and provides safer air evacuations for severely burned patients. (Source: Military Medical Research)
Source: Military Medical Research - May 13, 2021 Category: International Medicine & Public Health Source Type: research
Urinary bladder cancer as a late sequela of traumatic spinal cord injury
ConclusionsThe results showed that urinary bladder cancer in SCI patients differs considerably from that in able-bodied patients. The presented algorithm is an important aid in everyday clinical practice for assessing the correlation between SCI and bladder cancer. (Source: Military Medical Research)
Source: Military Medical Research - April 29, 2021 Category: International Medicine & Public Health Source Type: research
