Comparison of acute pneumonia caused by SARS-COV-2 and other respiratory viruses in children: a retrospective multi-center cohort study during COVID-19 outbreak
ConclusionThe symptoms and severity of COVID-19 pneumonia in children were no more severe than those in children with other viral pneumonia. Lopinavir-ritonavir, ribavirin and arbidol do not shorten the duration of positive PCR results from pharyngeal swabs in children with COVID-19. During the COVID-19 outbreak, attention also must be given to children with infection by other pathogens infection. (Source: Military Medical Research)
Source: Military Medical Research - February 16, 2021 Category: International Medicine & Public Health Source Type: research
Association between medical resources and the proportion of oldest-old in the Chinese population
AbstractThe potential association between medical resources and the proportion of oldest-old (90 years of age and above) in the Chinese population was examined, and we found that the higher proportion of oldest-old was associated with the higher number of beds in hospitals and health centers. (Source: Military Medical Research)
Source: Military Medical Research - February 16, 2021 Category: International Medicine & Public Health Source Type: research
Correction to: Combating an invisible enemy: the American military response to global pandemics
An amendment to this paper has been published and can be accessed via the original article. (Source: Military Medical Research)
Source: Military Medical Research - February 4, 2021 Category: International Medicine & Public Health Source Type: research
Development of rapid advice guideline and standard and continuous updating guideline: experiences and practice
AbstractWe published rapid advice guidelines and updated guidelines for coronavirus disease 2019 (COVID-19) management on February 6, 2020, and September 4, 2020, respectively. These two guidelines vary widely in their developmental background, type of evidence, grade of recommendation and so on. We shared our experience for the development of these two guidelines to help clinical practitioners better understand and implement guidelines and to help guideline developers facilitate communication and discussion for guideline development during the pandemic. (Source: Military Medical Research)
Source: Military Medical Research - February 3, 2021 Category: International Medicine & Public Health Source Type: research
Immunotherapeutic strategies targeting B cell maturation antigen in multiple myeloma
AbstractMultiple myeloma (MM) is the second most common hematologic malignancy, and is characterized by the clonal expansion of malignant plasma cells. Despite the recent improvement in patient outcome due to the use of novel therapeutic agents and stem cell transplantation, all patients eventually relapse due to clone evolution. B cell maturation antigen (BCMA) is highly expressed in and specific for MM cells, and has been implicated in the pathogenesis as well as treatment development for MM. In this review, we will summarize representative anti-BCMA immune therapeutic strategies, including BCMA-targeted vaccines, anti-B...
Source: Military Medical Research - January 27, 2021 Category: International Medicine & Public Health Source Type: research
Combating an invisible enemy: the American military response to global pandemics
AbstractThe present moment is not the first time that America has found itself at war with a pathogen during a time of international conflict. Between crowded barracks at home and trenches abroad, wartime conditions helped enable the spread of influenza in the fall of 1918 during World War I such that an estimated 20 –40% of U.S. military members were infected. While the coronavirus disease 2019 (COVID-19) pandemic is unparalleled for most of today’s population, it is essential to not view it as unprecedented lest the lessons of past pandemics and their effect on the American military be forgotten. This arti cle provid...
Source: Military Medical Research - January 25, 2021 Category: International Medicine & Public Health Source Type: research
A practical approach to imaging characteristics and standardized reporting of COVID-19: a radiologic review
AbstractNovel coronavirus (2019-nCoV), also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a pathogen that has caused a rapidly spreading pandemic all over the world. The primary mean of transmission is inhalation with a predilection for respiratory system involvement, especially in the distal airways. The disease that arises from this novel coronavirus is named coronavirus disease 2019 (COVID-19). COVID-19 may have a rapid and devastating course in some cases leading to severe complications and death. Radiological imaging methods have an invaluable role in diagnosis, follow-up, and treatment. In...
Source: Military Medical Research - January 24, 2021 Category: International Medicine & Public Health Source Type: research
Research progress of heat stroke during 1989 –2019: a bibliometric analysis
ConclusionsCorresponding to this important field, while the contributions of the publications from the United States were significant, the mismatch between the quantity and quality of publications from China must be examined. Moreover, it is hypothesized that clinical and epidemiological studies may become hotspots in the near future. (Source: Military Medical Research)
Source: Military Medical Research - January 21, 2021 Category: International Medicine & Public Health Source Type: research
Expert consensus on the prevention, diagnosis and treatment of cold injury in China, 2020
AbstractCold injury refers to local or systemic injury caused by a rapid, massive loss of body heat in a cold environment. The incidence of cold injury is high. However, the current situation regarding the diagnosis and treatment of cold injury in our country is not ideal. To standardize and improve the level of clinical diagnosis and treatment of cold injury in China, it is necessary to make a consensus that is practical and adapted to the conditions in China. We used the latest population-level epidemiological and clinical research data, combined with relevant literature from China and foreign countries. The consensus wa...
Source: Military Medical Research - January 21, 2021 Category: International Medicine & Public Health Source Type: research
Correction to: Extremity soft tissue coverage in the combat zone: use of pedicled flap transfers by the deployed orthopedic surgeon
An amendment to this paper has been published and can be accessed via the original article. (Source: Military Medical Research)
Source: Military Medical Research - January 21, 2021 Category: International Medicine & Public Health Source Type: research
Preparing for a “dirty bomb” attack: the optimum mix of medical countermeasure resources
ConclusionTo achieve economic efficiency a high daily screening capacity is of major importance to substantially decrease the required amount of antidote doses. Among the determinants of the number of equipment units needed, the fraction of the potentially contaminated victims that actually needs treatment is the most difficult to assess. Judging cost-effectiveness of the preparedness for “dirty bomb” attacks is an issue of principle that must be dealt with by political leaders. (Source: Military Medical Research)
Source: Military Medical Research - January 17, 2021 Category: International Medicine & Public Health Source Type: research
Repair cell first, then regenerate the tissues and organs
AbstractWound healing, tissue repair and regenerative medicine are in great demand, and great achievements in these fields have been made. The traditional strategy of tissue repair and regeneration has focused on the level of tissues and organs directly; however, the basic process of repair at the cell level is often neglected. Because the cell is the basic unit of organism structure and function; cell damage is caused first by ischemia or ischemia-reperfusion after severe trauma and injury. Then, damage to tissues and organs occurs with massive cell damage, apoptosis and even cell death. Thus, how to achieve the aim of pe...
Source: Military Medical Research - January 15, 2021 Category: International Medicine & Public Health Source Type: research
SARS-CoV-2: vaccines in the pandemic era
AbstractCoronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused millions of infections and deaths worldwide since its emergence in December 2019. As there is little or no natural immunity in the human population or specific anti-COVID-19 drugs, researchers from the government, academia and industry are developing vaccines at an unprecedented speed to halt the pandemic. In this review, the results of animal experiments and clinical trials on several vaccine technical platforms are summarized, and several challenges are also discussed to further promote the ...
Source: Military Medical Research - January 6, 2021 Category: International Medicine & Public Health Source Type: research
Spine system changes in soldiers after load carriage training in a plateau environment: a prediction model research
ConclusionThe spinal system encountered increased muscle volume, muscle congestion, tissue edema, IVD compression, decreased effective intervertebral foramen area, and increased lumbar curvature after LCT, which revealed important pathophysiological mechanisms of lumbar spinal disorders in soldiers following short-term and high-load weight training. The injury prediction model of the spinal system confirmed that a load weight < 60% of soldiers’ weight cannot cause acute pathological injury after short-term LCT, providing a reference supporting the formulation of the load weight standard for LCT. (Source: Military Medical Research)
Source: Military Medical Research - December 21, 2020 Category: International Medicine & Public Health Source Type: research
Impact of adolescent complex regional pain syndrome on the psychopathology of young men ahead of military service: a retrospective cohort analysis of Korean conscription data
ConclusionsPain duration is associated with psychopathology in adolescents with CRPS. Psychopathologic features increased as the disease duration increased. A comprehensive understanding of time-dependent psychopathological factors could support the planning of multimodal approaches for managing adolescent CRPS. (Source: Military Medical Research)
Source: Military Medical Research - December 21, 2020 Category: International Medicine & Public Health Source Type: research
